{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T11:34:27Z","timestamp":1789299267733,"version":"build-2803163510"},"reference-count":90,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T00:00:00Z","timestamp":1739836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018607","name":"Henan Province Science and Technology Innovation Talent Program","doi-asserted-by":"publisher","award":["244200510010"],"award-info":[{"award-number":["244200510010"]}],"id":[{"id":"10.13039\/501100018607","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005045","name":"Ministry of Finance","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005045","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011798","name":"Ministry of Agriculture and Rural Affairs of the People's Republic of China","doi-asserted-by":"publisher","award":["CARS-34"],"award-info":[{"award-number":["CARS-34"]}],"id":[{"id":"10.13039\/501100011798","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.psj.2025.104925","type":"journal-article","created":{"date-parts":[[2025,2,20]],"date-time":"2025-02-20T02:59:43Z","timestamp":1740020383000},"page":"104925","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Zinc Glycine supplementation improves bone quality in meat geese by modulating gut microbiota, SCFA's, and gut barrier function through Wnt10b\/NF-\u03baB axis"],"prefix":"10.1016","volume":"104","author":[{"given":"Zeshan","family":"Zulfiqar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Arslan","family":"Asif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid reza Rafieian","family":"Naeini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yalei","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boshuai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinghua","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2025.104925_bib0001","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1007\/s00198-013-2313-x","article-title":"NF-\u03bab signaling and bone resorption","volume":"24","author":"Abu-Amer","year":"2013","journal-title":"Osteoporos Int."},{"key":"10.1016\/j.psj.2025.104925_bib0002","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.livsci.2019.03.008","article-title":"Effect of different sources and contents of zinc on growth performance, carcass characteristics, humoral immunity and antioxidant status of broiler chickens exposed to high environmental temperatures","volume":"223","author":"Akhavan-Salamat","year":"2019","journal-title":"Livestock Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0003","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1041070","article-title":"Pasture intake protects against commercial diet-induced lipopolysaccharide production facilitated by gut microbiota through activating intestinal alkaline phosphatase enzyme in meat geese","volume":"13","author":"Ali","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2025.104925_bib0004","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.3390\/ani10091482","article-title":"Bioavailability of methionine-coated zinc nanoparticles as a dietary supplement leads to improved performance and bone strength in broiler chicken production","volume":"10","author":"Alkhtib","year":"2020","journal-title":"Animals"},{"key":"10.1016\/j.psj.2025.104925_bib0005","doi-asserted-by":"crossref","first-page":"27285","DOI":"10.1074\/jbc.M702810200","article-title":"Skeletal involution by age-associated oxidative stress and its acceleration by loss of sex steroids","volume":"282","author":"Almeida","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.psj.2025.104925_bib0006","doi-asserted-by":"crossref","first-page":"001","DOI":"10.1590\/1806-9061-2019-1245","article-title":"Comparative effect of zinc concentration and sources on growth performance, accumulation in tissues, tibia status, mineral excretion and immunity of broiler chickens","volume":"22","author":"Azad","year":"2020","journal-title":"Braz. J. Poult. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0007","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1002\/jbmr.1766","article-title":"Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia","volume":"28","author":"Barros","year":"2013","journal-title":"J. Bone Mineral Res."},{"key":"10.1016\/j.psj.2025.104925_bib0008","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2024.1392418","article-title":"The short-chain fatty acid receptors Gpr41\/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells","volume":"15","author":"Behler-Janbeck","year":"2024","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.psj.2025.104925_bib0009","doi-asserted-by":"crossref","first-page":"3324","DOI":"10.1073\/pnas.0408742102","article-title":"Regulation of osteoblastogenesis and bone mass by Wnt10b","volume":"102","author":"Bennett","year":"2005","journal-title":"Proc. Natl. Acad. Sci. USA."},{"key":"10.1016\/j.psj.2025.104925_bib0010","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1359\/jbmr.070810","article-title":"Wnt10b Increases postnatal bone formation by enhancing osteoblast differentiation","volume":"22","author":"Bennett","year":"2007","journal-title":"J. Bone Mineral Res."},{"key":"10.1016\/j.psj.2025.104925_bib0011","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1152\/physrev.00004.2015","article-title":"Histone deacetylases in bone development and skeletal disorders","volume":"95","author":"Bradley","year":"2015","journal-title":"Physiolog. Rev."},{"key":"10.1016\/j.psj.2025.104925_bib0012","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.4049\/jimmunol.1301261","article-title":"Differential regulation of TLR-dependent MyD88 and TRIF signaling pathways by free zinc ions","volume":"191","author":"Brieger","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.psj.2025.104925_bib0013","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.bone.2011.08.010","article-title":"Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a \u03b2-catenin-dependent mechanism","volume":"50","author":"Cawthorn","year":"2012","journal-title":"Bone"},{"key":"10.1016\/j.psj.2025.104925_bib0014","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.849067","article-title":"Effect of dietary zinc methionine supplementation on growth performance, immune function and intestinal health of Cherry Valley ducks challenged with avian pathogenic Escherichia coli","volume":"13","author":"Chang","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2025.104925_bib0015","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40104-023-00962-w","article-title":"Zinc glycine chelate ameliorates DSS-induced intestinal barrier dysfunction via attenuating TLR4\/NF-\u03bab pathway in meat ducks","volume":"15","author":"Chang","year":"2024","journal-title":"J. Animal Sci. Biotechnol."},{"key":"10.1016\/j.psj.2025.104925_bib0016","doi-asserted-by":"crossref","first-page":"skad279","DOI":"10.1093\/jas\/skad279","article-title":"Organic zinc glycine chelate is better than inorganic zinc in improving growth performance of cherry valley ducks by regulating intestinal morphology, barrier function, and the gut microbiome","volume":"101","author":"Chang","year":"2023","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0017","doi-asserted-by":"crossref","first-page":"5175","DOI":"10.1016\/j.psj.2020.08.047","article-title":"The application of micro-CT in egg-laying hen bone analysis: introducing an automated bone separation algorithm","volume":"99","author":"Chen","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102135","article-title":"Requirement of digestible calcium at different dietary concentrations of digestible phosphorus for broiler chickens. 2. Broiler growers (d 11 to 24 post-hatch)","volume":"101","author":"David","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0019","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3382\/ps\/pez525","article-title":"Dietary zinc source impacts intestinal morphology and oxidative stress in young broilers","volume":"99","author":"De Grande","year":"2020","journal-title":"Poult Sci"},{"key":"10.1016\/j.psj.2025.104925_bib0020","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1080\/07315724.2014.929511","article-title":"Effect of Zinc supplementation on GH, IGF1, IGFBP3, OCN, and ALP in non-zinc-deficient children","volume":"34","author":"De Medeiros Rocha","year":"2015","journal-title":"J. Am. College Nutrition"},{"key":"10.1016\/j.psj.2025.104925_bib0021","doi-asserted-by":"crossref","first-page":"5617","DOI":"10.1038\/s41467-022-33313-w","article-title":"Lactobacillus supports Clostridiales to restrict gut colonization by multidrug-resistant Enterobacteriaceae","volume":"13","author":"Djukovic","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.psj.2025.104925_bib0022","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1177\/1535370217693322","article-title":"Dietary 2-oxoglutarate prevents bone loss caused by neonatal treatment with maximal dexamethasone dose","volume":"242","author":"Dobrowolski","year":"2017","journal-title":"Exp. Biol. Med. (Maywood)"},{"key":"10.1016\/j.psj.2025.104925_bib0023","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.3390\/ijms22041568","article-title":"Critical role of estrogens on bone homeostasis in both male and female: from physiology to medical implications","volume":"22","author":"Emmanuelle","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0024","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1007\/s12275-020-0056-x","article-title":"Chitosan-chelated zinc modulates cecal microbiota and attenuates inflammatory response in weaned rats challenged with Escherichia coli","volume":"58","author":"Feng","year":"2020","journal-title":"J. Microbiol."},{"key":"10.1016\/j.psj.2025.104925_bib0025","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.720728","article-title":"Bone phenotyping approaches in human, mice and zebrafish \u2013 expert overview of the EU cost action GEMSTONE (\u201cGEnomics of MusculoSkeletal traits TranslatiOnal NEtwork\u201d)","volume":"12","author":"Foessl","year":"2021","journal-title":"Front. Endocrinol"},{"key":"10.1016\/j.psj.2025.104925_bib0026","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s00223-015-9961-0","article-title":"Glutathione, N-acetylcysteine and lipoic acid down-regulate starvation-induced apoptosis, RANKL\/OPG ratio and sclerostin in osteocytes: involvement of JNK and ERK1\/2 signalling","volume":"96","author":"Fontani","year":"2015","journal-title":"Calcif. Tissue Int."},{"key":"10.1016\/j.psj.2025.104925_bib0027","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s13018-020-01585-x","article-title":"Zinc promotes cell apoptosis via activating the wnt-3a\/\u03b2-catenin signaling pathway in osteosarcoma","volume":"15","author":"Gao","year":"2020","journal-title":"J. Orthop. Surg. Res."},{"key":"10.1016\/j.psj.2025.104925_bib0028","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1177\/9.2.141","article-title":"Distribution of zinc in bone tissue","volume":"9","author":"Haumont","year":"1961","journal-title":"J. Histochem. Cytochem"},{"key":"10.1016\/j.psj.2025.104925_bib0029","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/s41413-024-00342-8","article-title":"Wnt\/\u03b2-catenin signaling components and mechanisms in bone formation, homeostasis, and disease","volume":"12","author":"Hu","year":"2024","journal-title":"Bone Res"},{"key":"10.1016\/j.psj.2025.104925_bib0030","doi-asserted-by":"crossref","unstructured":"Huang, S., Y. He, L. Lin, T. Xu, and A. Shaukat. 2022. Targeting gut microbiota in bone health of livestock and poultry: roles of short-chain fatty acids. Available at https:\/\/www.researchsquare.com\/article\/rs-2019685\/v1 (verified 29 November 2024).","DOI":"10.21203\/rs.3.rs-2019685\/v1"},{"key":"10.1016\/j.psj.2025.104925_bib0031","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1038\/nm1197-1285","article-title":"Osteopetrosis in mice lacking NF-\u03baB1 and NF-\u03baB2","volume":"3","author":"Iotsova","year":"1997","journal-title":"Nat. Med."},{"key":"10.1016\/j.psj.2025.104925_bib0032","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s10787-017-0309-4","article-title":"Antioxidant and anti-inflammatory effects of zinc. Zinc-dependent NF-\u03bab signaling","volume":"25","author":"Jarosz","year":"2017","journal-title":"Inflammopharmacol"},{"key":"10.1016\/j.psj.2025.104925_bib0033","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.bone.2012.11.038","article-title":"Osteocyte apoptosis","volume":"54","author":"Jilka","year":"2013","journal-title":"Bone"},{"key":"10.1016\/j.psj.2025.104925_bib0034","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1080\/00071660903421159","article-title":"Environment and management factors affecting Pekin duck production and welfare on commercial farms in the UK","volume":"51","author":"Jones","year":"2010","journal-title":"British Poultry Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0035","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/j.1600-079X.2006.00353.x","article-title":"Effects of melatonin and zinc on lipid profile and renal function in type 2 diabetic patients poorly controlled with metformin","volume":"41","author":"Kadhim","year":"2006","journal-title":"J. Pineal Res."},{"key":"10.1016\/j.psj.2025.104925_bib0036","doi-asserted-by":"crossref","first-page":"277","DOI":"10.4110\/in.2014.14.6.277","article-title":"Gut microbiota-derived short-chain fatty acids, T cells, and inflammation","volume":"14","author":"Kim","year":"2014","journal-title":"Immune Netw."},{"key":"10.1016\/j.psj.2025.104925_bib0037","first-page":"307","article-title":"Zinc nutritional status modulates the 1,25-(OH)2D. Response in uremic rats","volume":"17","author":"Kimmel","year":"1991","journal-title":"Miner. Electrolyte Metab."},{"key":"10.1016\/j.psj.2025.104925_bib0038","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s40261-019-00868-4","article-title":"Influence of prevalent vertebral fracture on the correlation between change in lumbar spine bone mineral density and risk of new vertebral fracture: a meta-analysis of randomized clinical trials","volume":"40","author":"Kobayashi","year":"2020","journal-title":"Clin. Drug Investig."},{"key":"10.1016\/j.psj.2025.104925_bib0039","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/j.cell.2016.05.041","article-title":"From dietary fiber to host physiology: short-chain fatty acids as key bacterial metabolites","volume":"165","author":"Koh","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.psj.2025.104925_bib0040","series-title":"Page 16 in First International Electronic Conference on Nutrients, Microbiota and Chronic Disease","article-title":"Chronic dietary zinc deficiency alters gut microbiota composition and function","author":"Koren","year":"2020"},{"key":"10.1016\/j.psj.2025.104925_bib0041","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.livsci.2016.07.005","article-title":"Effects of zinc glycine chelate on growth performance, carcass characteristics, bone quality, and mineral content in bone of broiler chicken","volume":"191","author":"Kwiecie\u0144","year":"2016","journal-title":"Livestock Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0042","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1172\/JCI11176","article-title":"TNF-\u03b1 induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand","volume":"106","author":"Lam","year":"2000","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.psj.2025.104925_bib0043","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/9156285","article-title":"Critical role of zinc as either an antioxidant or a prooxidant in cellular systems","volume":"2018","author":"Lee","year":"2018","journal-title":"Oxidative Med. Cellular Longevity"},{"key":"10.1016\/j.psj.2025.104925_bib0044","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1038\/4441022a","article-title":"Human gut microbes associated with obesity","volume":"444","author":"Ley","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.psj.2025.104925_bib0045","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2021.1968257","article-title":"Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel disease","volume":"13","author":"Li","year":"2021","journal-title":"Gut Microb."},{"key":"10.1016\/j.psj.2025.104925_bib0046","article-title":"Roles of the RANKL\u2013RANK axis in immunity\u2014Implications for pathogenesis and treatment of bone metastasis","volume":"13","author":"Li","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2025.104925_bib0047","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.3382\/ps\/pev124","article-title":"Bacillus amyloliquefaciens supplementation alleviates immunological stress in lipopolysaccharide-challenged broilers at early age","volume":"94","author":"Li","year":"2015","journal-title":"Poultry Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0048","doi-asserted-by":"crossref","first-page":"11200","DOI":"10.1096\/fj.202000786R","article-title":"The relationship between gut microbiota and short chain fatty acids in the renal calcium oxalate stones disease","volume":"34","author":"Liu","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.psj.2025.104925_bib0049","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2021.736739","article-title":"Biological function of short-chain fatty acids and its regulation on intestinal health of poultry","volume":"8","author":"Liu","year":"2021","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0050","doi-asserted-by":"crossref","first-page":"138","DOI":"10.22358\/jafs\/157475\/2023","article-title":"25-hydroxycholecalciferol affects growth performance,bone calcium content and intestinal calcium transportergene expression in broiler chickens","volume":"32","author":"Liu","year":"2023","journal-title":"J. Anim. Feed Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0051","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.psj.2025.104925_bib0052","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41467-017-02490-4","article-title":"Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss","volume":"9","author":"Lucas","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.psj.2025.104925_bib0053","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s12011-014-9910-1","article-title":"Chitosan-Zn chelate increases antioxidant enzyme activity and improves immune function in weaned piglets","volume":"158","author":"Ma","year":"2014","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2025.104925_bib0055","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3906\/vet-1405-79","article-title":"Effect of organic zinc supplementation on growth, nutrient utilization,and plasma zinc status in lambs","volume":"39","author":"Mallaki","year":"2015","journal-title":"Turk J. Vet Anim. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0056","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.tem.2022.01.002","article-title":"Gut barrier disruption and chronic disease","volume":"33","author":"Martel","year":"2022","journal-title":"Trend. Endocrinol. Metabol."},{"key":"10.1016\/j.psj.2025.104925_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101254","article-title":"Zinc hydroxychloride supplementation improves tibia bone development and intestinal health of broiler chickens","volume":"100","author":"Nguyen","year":"2021","journal-title":"Poultry Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0058","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.3390\/ma13102211","article-title":"Zinc as a therapeutic agent in bone regeneration","volume":"13","author":"O'Connor","year":"2020","journal-title":"Materials"},{"key":"10.1016\/j.psj.2025.104925_bib0059","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.3390\/ma13102211","article-title":"Zinc as a therapeutic agent in bone regeneration","volume":"13","author":"O'Connor","year":"2020","journal-title":"Materials"},{"key":"10.1016\/j.psj.2025.104925_bib0060","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1515\/aoas-2016-0055","article-title":"Effects of dietary supplementation of inorganic, organic or nano zinc forms on performance, eggshell quality, and bone characteristics in laying hens","volume":"17","author":"Olgun","year":"2017","journal-title":"Annal. Animal Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0061","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1038\/s41396-020-0730-3","article-title":"Concentration and chemical form of dietary zinc shape the porcine colon microbiome, its functional capacity and antibiotic resistance gene repertoire","volume":"14","author":"Pieper","year":"2020","journal-title":"ISME J."},{"key":"10.1016\/j.psj.2025.104925_bib0062","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1093\/ps\/79.7.1024","article-title":"Factors regulating bone maturity and strength in poultry","volume":"79","author":"Rath","year":"2000","journal-title":"Poultry Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0063","doi-asserted-by":"crossref","first-page":"6291","DOI":"10.1021\/acs.jafc.8b01481","article-title":"Alterations in the gut (Gallus gallus) microbiota following the consumption of zinc biofortified wheat (Triticum aestivum)-based diet","volume":"66","author":"Reed","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.psj.2025.104925_bib0064","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1002\/ajpa.1330360211","article-title":"Metatarsal robusticity in bipedal rats","volume":"36","author":"Riesenfeld","year":"1972","journal-title":"American J Phys Anthropol"},{"key":"10.1016\/j.psj.2025.104925_bib0065","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1111\/febs.12075","article-title":"Role of GSH \/GSSG redox couple in osteogenic activity and osteoclastogenic markers of human osteoblast-like Sa OS -2 cells","volume":"280","author":"Romagnoli","year":"2013","journal-title":"FEBS J."},{"key":"10.1016\/j.psj.2025.104925_bib0066","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1038\/nri2515","article-title":"The gut microbiota shapes intestinal immune responses during health and disease","volume":"9","author":"Round","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.psj.2025.104925_bib0067","doi-asserted-by":"crossref","first-page":"G229","DOI":"10.1152\/ajpgi.00092.2018","article-title":"Zinc ameliorates intestinal barrier dysfunctions in shigellosis by reinstating claudin-2 and -4 on the membranes","volume":"316","author":"Sarkar","year":"2019","journal-title":"Am. J. Physiol.-Gastroint. Liver Physiol."},{"key":"10.1016\/j.psj.2025.104925_bib0068","doi-asserted-by":"crossref","first-page":"9452","DOI":"10.3390\/ijms22179452","article-title":"The Human gut microbiota: a key mediator of osteoporosis and osteogenesis","volume":"22","author":"Seely","year":"2021","journal-title":"IJMS"},{"key":"10.1016\/j.psj.2025.104925_bib0069","doi-asserted-by":"crossref","first-page":"356","DOI":"10.4162\/nrp.2010.4.5.356","article-title":"Zinc may increase bone formation through stimulating cell proliferation, alkaline phosphatase activity and collagen synthesis in osteoblastic MC3T3-E1 cells","volume":"4","author":"Seo","year":"2010","journal-title":"Nutr. Res. Pract."},{"key":"10.1016\/j.psj.2025.104925_bib0070","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jnutbio.2017.01.013","article-title":"Zinc enhances intestinal epithelial barrier function through the PI3K\/AKT\/mTOR signaling pathway in Caco-2 cells","volume":"43","author":"Shao","year":"2017","journal-title":"J. Nutrit. Biochem."},{"key":"10.1016\/j.psj.2025.104925_bib0071","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3390\/ani12020181","article-title":"Influence of the zinc and fibre addition in the diet on biomechanical bone properties in weaned piglets","volume":"12","author":"Skiba","year":"2022","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.psj.2025.104925_bib0072","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1080\/00071660310001643750","article-title":"The effect of dietary fibre on the small intestines and apparent digestion in the turkey","volume":"44","author":"Sklan","year":"2003","journal-title":"British Poult. Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0073","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.3390\/nu14193921","article-title":"Zinc supplementation partially decreases the harmful effects of a cafeteria diet in rats but does not prevent intestinal dysbiosis","volume":"14","author":"Squizani","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.psj.2025.104925_bib0074","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1530\/JOE-12-0143","article-title":"The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling","volume":"214","author":"Staines","year":"2012","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.psj.2025.104925_bib0075","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jtemb.2017.12.005","article-title":"The beneficial effects of Zn on Akt-mediated insulin and cell survival signaling pathways in diabetes","volume":"46","author":"Sun","year":"2018","journal-title":"J. Trace Element. Med. Biol."},{"key":"10.1016\/j.psj.2025.104925_bib0076","doi-asserted-by":"crossref","first-page":"16817","DOI":"10.1074\/jbc.R117.800169","article-title":"Stress-sensing mechanisms and the physiological roles of the Keap1\u2013Nrf2 system during cellular stress","volume":"292","author":"Suzuki","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.psj.2025.104925_bib0077","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1002\/JLB.3MR0321-755R","article-title":"The microbiota-gut-bone axis and bone health","volume":"110","author":"Tu","year":"2021","journal-title":"J. Leukoc Biol."},{"key":"10.1016\/j.psj.2025.104925_bib0078","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.immuni.2018.10.013","article-title":"The microbial metabolite butyrate stimulates bone formation via T regulatory cell-mediated regulation of WNT10B expression","volume":"49","author":"Tyagi","year":"2018","journal-title":"Immunity"},{"key":"10.1016\/j.psj.2025.104925_bib0079","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1007\/s12011-022-03207-5","article-title":"Dietary zinc glycine supplementation improves Tibia quality of meat ducks by modulating the intestinal barrier and bone resorption","volume":"201","author":"Wang","year":"2023","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2025.104925_bib0080","article-title":"Effects of Icariin on modulating gut microbiota and regulating metabolite alterations to prevent bone loss in ovariectomized rat model","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Endocrinol. (Lausanne)"},{"key":"10.1016\/j.psj.2025.104925_bib0081","article-title":"Effect of bifidobacterium on osteoclasts: tNF-\u03b1\/NF-\u03bab inflammatory signal pathway-mediated mechanism","volume":"14","author":"Wu","year":"2023","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.psj.2025.104925_bib0082","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2024.116111","article-title":"Zinc glycinate alleviates LPS-induced inflammation and intestinal barrier disruption in chicken embryos by regulating zinc homeostasis and TLR4\/NF-\u03bab pathway","volume":"272","author":"Xiao","year":"2024","journal-title":"Ecotoxicol. Environ. Safety"},{"key":"10.1016\/j.psj.2025.104925_bib0083","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s11010-009-0358-0","article-title":"Role of nutritional zinc in the prevention of osteoporosis","volume":"338","author":"Yamaguchi","year":"2010","journal-title":"Mol. Cell Biochem."},{"key":"10.1016\/j.psj.2025.104925_bib0084","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s11010-011-0852-z","article-title":"Zinc stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-\u03bab activation","volume":"355","author":"Yamaguchi","year":"2011","journal-title":"Mol. Cell Biochem."},{"key":"10.1016\/j.psj.2025.104925_bib0085","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.918283","article-title":"Effects of zinc methionine hydroxy analog chelate on laying performance, serum hormone levels, and expression of reproductive axis related Genes in Aged Broiler Breeders","volume":"9","author":"Yang","year":"2022","journal-title":"Front. Vet Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0086","doi-asserted-by":"crossref","first-page":"156","DOI":"10.15252\/embr.201744421","article-title":"Regulatory T cells are expanded by Teriparatide treatment in humans and mediate intermittent PTH -induced bone anabolism in mice","volume":"19","author":"Yu","year":"2018","journal-title":"EMBO Repor."},{"key":"10.1016\/j.psj.2025.104925_bib0087","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/jpn.12255","article-title":"Zinc glycine chelate absorption characteristics in S prague D awley rat","volume":"99","author":"Yue","year":"2015","journal-title":"Animal Physiol. Nutr."},{"key":"10.1016\/j.psj.2025.104925_bib0088","doi-asserted-by":"crossref","first-page":"skz373","DOI":"10.1093\/jas\/skz373","article-title":"Dietary pterostilbene supplementation attenuates intestinal damage and immunological stress of broiler chickens challenged with lipopolysaccharide","volume":"98","author":"Zhang","year":"2020","journal-title":"J. Animal Sci."},{"key":"10.1016\/j.psj.2025.104925_bib0089","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s40104-021-00627-6","article-title":"25-hydroxycholecalciferol reverses heat induced alterations in bone quality in finisher broilers associated with effects on intestinal integrity and inflammation","volume":"12","author":"Zhang","year":"2021","journal-title":"J. Animal Sci. Biotechnol."},{"key":"10.1016\/j.psj.2025.104925_bib0090","article-title":"Dietary resistant starch from potato regulates bone mass by modulating gut microbiota and concomitant short-chain fatty acids production in meat ducks","volume":"9","author":"Zhang","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.psj.2025.104925_bib0091","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1017\/S0007114518002556","article-title":"Effect of graded calcium supplementation in low-nutrient density feed on tibia composition and bone turnover in meat ducks","volume":"120","author":"Zhang","year":"2018","journal-title":"Br J. Nutr."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125001646?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125001646?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:58:02Z","timestamp":1762217882000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125001646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":90,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["S0032579125001646"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.104925","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zinc Glycine supplementation improves bone quality in meat geese by modulating gut microbiota, SCFA's, and gut barrier function through Wnt10b\/NF-\u03baB axis","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.104925","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"104925"}}