{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T20:07:21Z","timestamp":1780085241387,"version":"3.54.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012438","name":"Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System","doi-asserted-by":"publisher","award":["SCCXTD-2020-18"],"award-info":[{"award-number":["SCCXTD-2020-18"]}],"id":[{"id":"10.13039\/501100012438","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003459","name":"Guizhou University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003459","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011798","name":"Ministry of Agriculture and Rural Affairs of the People's Republic of China","doi-asserted-by":"publisher","award":["CARS-42-17"],"award-info":[{"award-number":["CARS-42-17"]}],"id":[{"id":"10.13039\/501100011798","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.psj.2025.105092","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T14:46:26Z","timestamp":1742913986000},"page":"105092","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Duck plague virus UL47 gene affects the release and cell-to-cell spread of the virus and its deletion strains can provide strong protection for ducks"],"prefix":"10.1016","volume":"104","author":[{"given":"Yuxi","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingshu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xumin","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaqiu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dekang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mafeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renyong","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6093-353X","authenticated-orcid":false,"given":"Anchun","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2025.105092_bib0001","doi-asserted-by":"crossref","first-page":"4889","DOI":"10.1128\/JVI.00017-16","article-title":"VP8, the major tegument protein of Bovine Herpesvirus 1, interacts with cellular STAT1 and inhibits interferon beta signaling","volume":"90","author":"Afroz","year":"2016","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0002","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.virusres.2018.12.006","article-title":"The Bovine herpesvirus-1 major tegument protein, VP8, interacts with host HSP60 concomitant with deregulation of mitochondrial function","volume":"261","author":"Afroz","year":"2019","journal-title":"Virus Res"},{"issue":"15","key":"10.1016\/j.psj.2025.105092_bib0003","doi-asserted-by":"crossref","first-page":"e00773","DOI":"10.1128\/JVI.00773-18","article-title":"The major tegument protein of Bovine Herpesvirus 1, VP8, interacts with DNA damage response proteins and induces apoptosis","volume":"92","author":"Afroz","year":"2018","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0004","doi-asserted-by":"crossref","first-page":"17401","DOI":"10.1016\/S0021-9258(17)32453-5","article-title":"An amino acid sequence shared by the Herpes Simplex Virus 1 alpha regulatory proteins 0, 4, 22, and 27 predicts the nucleotidylylation of the UL21, UL31, UL47, and UL49 gene products","volume":"269","author":"Blaho","year":"1994","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.psj.2025.105092_bib0005","doi-asserted-by":"crossref","first-page":"e01645","DOI":"10.1128\/JVI.01645-20","article-title":"The tegument protein pUL47 of Marek\u2019s Disease Virus is necessary for horizontal transmission and is important for expression of glycoprotein gC","volume":"95","author":"Chuard","year":"2020","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0006","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/01652176.2017.1298885","article-title":"Duck virus enteritis (duck plague) - a comprehensive update","volume":"37","author":"Dhama","year":"2017","journal-title":"Vet. Q."},{"key":"10.1016\/j.psj.2025.105092_bib0007","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1128\/JVI.75.6.2566-2574.2001","article-title":"Nuclear localization and shuttling of herpes simplex virus tegument protein VP13\/14","volume":"75","author":"Donnelly","year":"2001","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0008","doi-asserted-by":"crossref","first-page":"12891","DOI":"10.1128\/JVI.77.23.12891-12900.2003","article-title":"A pseudorabies virus recombinant simultaneously lacking the major tegument proteins encoded by the UL46, UL47, UL48, and UL49 genes is viable in cultured cells","volume":"77","author":"Fuchs","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0009","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.virusres.2014.09.003","article-title":"A novel inactivated gE\/gI deleted pseudorabies virus (PRV) vaccine completely protects pigs from an emerged variant PRV challenge","volume":"195","author":"Gu","year":"2015","journal-title":"Virus Res"},{"key":"10.1016\/j.psj.2025.105092_bib0010","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1743-422X-6-71","article-title":"Development of TaqMan MGB fluorescent real-time PCR assay for the detection of anatid herpesvirus 1","volume":"6","author":"Guo","year":"2009","journal-title":"Virol. J."},{"key":"10.1016\/j.psj.2025.105092_bib0011","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12985-018-0928-4","article-title":"Molecular characterization of duck enteritis virus UL41 protein","volume":"15","author":"He","year":"2018","journal-title":"Virol. J."},{"key":"10.1016\/j.psj.2025.105092_bib0012","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s13567-020-00859-w","article-title":"Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-\u03b2 signalling by interacting with STAT1","volume":"51","author":"He","year":"2020","journal-title":"Vet. Res."},{"key":"10.1016\/j.psj.2025.105092_bib0013","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1099\/vir.0.82533-0","article-title":"The UL47 gene of avian infectious laryngotracheitis virus is not essential for in vitro replication but is relevant for virulence in chickens","volume":"88","author":"Helferich","year":"2007","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0014","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1128\/CVI.00605-13","article-title":"An attenuated duck plague virus (DPV) vaccine induces both systemic and mucosal immune responses to protect ducks against virulent DPV infection","volume":"21","author":"Huang","year":"2014","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.psj.2025.105092_bib0015","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.virusres.2014.12.017","article-title":"Interaction of VP8 with mRNAs of bovine herpesvirus-1","volume":"197","author":"Islam","year":"2015","journal-title":"Virus Res"},{"key":"10.1016\/j.psj.2025.105092_bib0016","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.virol.2015.06.012","article-title":"Differential expression of Marek's disease virus (MDV) late proteins during in vitro and in situ replication: role for pUL47 in regulation of the MDV UL46-UL49 gene locus","volume":"484","author":"Jarosinski","year":"2015","journal-title":"Virology"},{"key":"10.1016\/j.psj.2025.105092_bib0017","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.979368","article-title":"Pathogenicity and transmissibility studies on live attenuated duck enteritis virus vaccine in non-target species","volume":"13","author":"Kong","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2025.105092_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102365","article-title":"Duck plague virus infection alter the microbiota composition and intestinal functional activity in Muscovy ducks","volume":"102","author":"Kong","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.105092_bib0019","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.1099\/vir.0.013532-0","article-title":"Major tegument protein VP8 of bovine herpesvirus 1 is phosphorylated by viral US3 and cellular CK2 protein kinases","volume":"90","author":"Labiuk","year":"2009","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0020","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s13567-017-0456-z","article-title":"RNA-seq comparative analysis of Peking ducks spleen gene expression 24 h post-infected with duck plague virulent or attenuated virus","volume":"48","author":"Liu","year":"2017","journal-title":"Vet. Res."},{"key":"10.1016\/j.psj.2025.105092_bib0021","doi-asserted-by":"crossref","first-page":"4657","DOI":"10.1128\/JVI.00137-14","article-title":"Herpes simplex virus 1 UL47 interacts with viral nuclear egress factors UL31, UL34, and Us3 and regulates viral nuclear egress","volume":"88","author":"Liu","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetmic.2021.109104","article-title":"Pathogenicity and immunogenicity of a gI\/gE\/TK\/UL13-gene-deleted variant pseudorabies virus strain in swine","volume":"258","author":"Lv","year":"2021","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.psj.2025.105092_bib0023","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1128\/jvi.68.3.1750-1757.1994","article-title":"An 85-kilodalton herpes simplex virus type 1 alpha trans-induction factor (VP16)-VP13\/14 fusion protein retains the transactivation and structural properties of the wild-type molecule during virus infection","volume":"68","author":"McKnight","year":"1994","journal-title":"J. Virol."},{"issue":"Pt 11","key":"10.1016\/j.psj.2025.105092_bib0024","doi-asserted-by":"crossref","first-page":"2771","DOI":"10.1099\/0022-1317-72-11-2771","article-title":"Post-translational modification of the tegument proteins (VP13 and VP14) of herpes simplex virus type 1 by glycosylation and phosphorylation","volume":"72","author":"Meredith","year":"1991","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0025","article-title":"Evaluation of the safety and immunogenicity of duck-plague virus gE mutants","volume":"13","author":"Ning","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2025.105092_bib0026","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s13567-024-01398-4","article-title":"N-glycosylation of the envelope glycoprotein I is essential for the proliferation and virulence of the duck plague virus","volume":"55","author":"Ning","year":"2024","journal-title":"Vet. Res."},{"key":"10.1016\/j.psj.2025.105092_bib0027","doi-asserted-by":"crossref","first-page":"19","DOI":"10.3390\/cells2010019","article-title":"CD8+ T lymphocyte epitopes from the herpes simplex virus type 2 ICP27, VP22 and VP13\/14 proteins to facilitate vaccine design and characterization","volume":"2","author":"Platt","year":"2013","journal-title":"Cells"},{"key":"10.1016\/j.psj.2025.105092_bib0028","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1128\/MMBR.00011-08","article-title":"Comparative genomics and molecular dynamics of DNA repeats in eukaryotes","volume":"72","author":"Richard","year":"2008","journal-title":"Microbiol. Mol. Biol. Rev."},{"issue":"2","key":"10.1016\/j.psj.2025.105092_bib0029","doi-asserted-by":"crossref","first-page":"e01793","DOI":"10.1128\/JVI.01793-16","volume":"91","author":"Srivastava","year":"2017","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0030","doi-asserted-by":"crossref","first-page":"5965","DOI":"10.1128\/JVI.00529-12","article-title":"Complete genomic sequence of Chinese virulent duck enteritis virus","volume":"86","author":"Wu","year":"2012","journal-title":"J. Virol."},{"key":"10.1016\/j.psj.2025.105092_bib0031","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1637\/9766-042111-Reg.1","article-title":"Serologic detection of duck enteritis virus using an indirect ELISA based on recombinant UL55 protein","volume":"55","author":"Wu","year":"2011","journal-title":"Avian Dis"},{"key":"10.1016\/j.psj.2025.105092_bib0032","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00983-23","article-title":"A recombinant duck plague virus containing the ICP27 deletion marker provides robust protection in ducks","volume":"11","author":"Wu","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.psj.2025.105092_bib0033","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.01140-22","article-title":"Deletion of double copies of the US1 gene reduces the infectivity of recombinant duck plague virus in vitro and in vivo","volume":"10","author":"Wu","year":"2022","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.psj.2025.105092_bib0034","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2023.2284301","article-title":"Recombinant duck enteritis virus bearing the hemagglutinin genes of H5 and H7 influenza viruses is an ideal multivalent live vaccine in ducks","volume":"13","author":"Zhao","year":"2024","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.psj.2025.105092_bib0035","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1128\/JVI.72.1.847-852.1998","article-title":"Gene arrangement within the unique long genome region of infectious laryngotracheitis virus is distinct from that of other alphaherpesviruses","volume":"72","author":"Ziemann","year":"1998","journal-title":"J. Virol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125003311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125003311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T00:57:45Z","timestamp":1762217865000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125003311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0032579125003311"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.105092","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Duck plague virus UL47 gene affects the release and cell-to-cell spread of the virus and its deletion strains can provide strong protection for ducks","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.105092","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"105092"}}