{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:08:55Z","timestamp":1791256135837,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:00:00Z","timestamp":1747180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011798","name":"Ministry of Agriculture and Rural Affairs of the People's Republic of China","doi-asserted-by":"publisher","award":["CARS-41"],"award-info":[{"award-number":["CARS-41"]}],"id":[{"id":"10.13039\/501100011798","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32372915"],"award-info":[{"award-number":["32372915"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005196","name":"Chinese Academy of Agricultural Sciences","doi-asserted-by":"publisher","award":["Y2023QC10"],"award-info":[{"award-number":["Y2023QC10"]}],"id":[{"id":"10.13039\/501100005196","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFD1800300"],"award-info":[{"award-number":["2024YFD1800300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFD1300703"],"award-info":[{"award-number":["2022YFD1300703"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.psj.2025.105296","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T11:40:39Z","timestamp":1747309239000},"page":"105296","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Fusion with CTB enhances the immunogenicity and protective efficacy of MIC2 subunit vaccine against Eimeria tenella"],"prefix":"10.1016","volume":"104","author":[{"given":"Hanbing","family":"Wei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sixuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huoqing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyun","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingguo","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiabo","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0127-1235","authenticated-orcid":false,"given":"Xinming","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiying","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6822-5359","authenticated-orcid":false,"given":"Honglian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.psj.2025.105296_bib0009","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1128\/CMR.15.1.58-65.2002","article-title":"Recent advances in biology and immunobiology of Eimeria species and in diagnosis and control of infection with these coccidian parasites of poultry","volume":"15","author":"Allen","year":"2002","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.psj.2025.105296_bib0010","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.3389\/fimmu.2018.02212","article-title":"The nontoxic cholera B subunit is a potent adjuvant for intradermal DC-targeted vaccination","volume":"9","author":"Antonio-Herrera","year":"2018","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.psj.2025.105296_bib0011","doi-asserted-by":"crossref","DOI":"10.3390\/toxins16030133","article-title":"The mutagenic plasticity of the cholera toxin B-subunit surface residues: stability and affinity","volume":"16","author":"Au","year":"2024","journal-title":"Toxins. (Basel)"},{"issue":"3","key":"10.1016\/j.psj.2025.105296_bib0012","doi-asserted-by":"crossref","first-page":"974","DOI":"10.3390\/toxins7030974","article-title":"Cholera toxin B: one subunit with many pharmaceutical applications","volume":"7","author":"Baldauf","year":"2015","journal-title":"Toxins. (Basel)"},{"issue":"7","key":"10.1016\/j.psj.2025.105296_bib0013","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0020-7519(02)00011-5","article-title":"Biochemical characterisation of the 56 and 82 kDa immunodominant gametocyte antigens from Eimeria maxima","volume":"32","author":"Belli","year":"2002","journal-title":"Int. J. Parasitol."},{"issue":"31-32","key":"10.1016\/j.psj.2025.105296_bib0001","doi-asserted-by":"crossref","first-page":"4316","DOI":"10.1016\/j.vaccine.2004.04.019","article-title":"Characterisation of the antigenic and immunogenic properties of bacterially expressed, sexual stage antigens of the coccidian parasite, Eimeria maxima","volume":"22","author":"Belli","year":"2004","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2025.105296_bib0002","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.meegid.2017.10.009","article-title":"Recombinant anticoccidial vaccines - a cup half full?","volume":"55","author":"Blake","year":"2017","journal-title":"Infect. Genet. Evol."},{"issue":"3","key":"10.1016\/j.psj.2025.105296_bib0014","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1080\/03079457.2024.2441180","article-title":"Eimeria of chickens: the changing face of an old foe","volume":"54","author":"Blake","year":"2025","journal-title":"Avian Pathol."},{"issue":"9","key":"10.1016\/j.psj.2025.105296_bib0003","article-title":"Immunogenic eimeria tenella glycosylphosphatidylinositol-anchored surface antigens (SAGs) induce inflammatory responses in avian macrophages","volume":"6","author":"Braga","year":"2011","journal-title":"PLoS. One"},{"issue":"1","key":"10.1016\/j.psj.2025.105296_bib0015","article-title":"Molecular identification of eimeria species in broiler chickens in Trinidad, West Indies","volume":"5","author":"Brown Jordan","year":"2018","journal-title":"Vet. Sci."},{"issue":"2","key":"10.1016\/j.psj.2025.105296_bib0016","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0166-6851(00)00280-2","article-title":"Induction of secretion and surface capping of microneme proteins in Eimeria tenella","volume":"110","author":"Bumstead","year":"2000","journal-title":"Mol. Biochem. Parasitol."},{"issue":"1","key":"10.1016\/j.psj.2025.105296_bib0004","first-page":"1","article-title":"Research progress of the avian coccidiosis vaccine","author":"Cai","year":"2022","journal-title":"Vet. Vaccine"},{"issue":"18","key":"10.1016\/j.psj.2025.105296_bib0017","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1016\/j.vaccine.2018.03.046","article-title":"Improving the immunogenicity and protective efficacy of the EtMIC2 protein against Eimeria tenella infection through random mutagenesis","volume":"36","author":"Chen","year":"2018","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.psj.2025.105296_bib0018","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1007\/s12010-012-0004-2","article-title":"Expression of cholera toxin B-lumbrokinase fusion protein in Pichia pastoris\u2013the use of transmucosal carriers in the delivery of therapeutic proteins to protect rats against thrombosis","volume":"169","author":"Chunfeng","year":"2013","journal-title":"Appl. Biochem. Biotechnol."},{"issue":"1","key":"10.1016\/j.psj.2025.105296_bib0019","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molbiopara.2012.08.007","article-title":"The molecular basis for the distinct host and tissue tropisms of coccidian parasites","volume":"186","author":"Cowper","year":"2012","journal-title":"Mol. Biochem. Parasitol."},{"issue":"2","key":"10.1016\/j.psj.2025.105296_bib0020","first-page":"89","article-title":"Production of pentameric cholera toxin B subunit in Escherichia coli","volume":"4","author":"Dakterzada","year":"2012","journal-title":"Avicenna J. Med. Biotechnol."},{"issue":"7","key":"10.1016\/j.psj.2025.105296_bib0021","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1111\/pbi.13060","article-title":"Cold chain and virus-free oral polio booster vaccine made in lettuce chloroplasts confers protection against all three poliovirus serotypes","volume":"17","author":"Daniell","year":"2019","journal-title":"Plant Biotechnol. J."},{"issue":"28","key":"10.1016\/j.psj.2025.105296_bib0022","doi-asserted-by":"crossref","first-page":"3733","DOI":"10.1016\/j.vaccine.2005.01.144","article-title":"In ovo vaccination with the Eimeria tenella EtMIC2 gene induces protective immunity against coccidiosis","volume":"23","author":"Ding","year":"2005","journal-title":"Vaccine"},{"issue":"4","key":"10.1016\/j.psj.2025.105296_bib0023","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1128\/IAI.71.4.1740-1747.2003","article-title":"Cholera toxin and its B subunit promote dendritic cell vaccination with different influences on Th1 and Th2 development","volume":"71","author":"Eriksson","year":"2003","journal-title":"Infect. Immun."},{"issue":"2","key":"10.1016\/j.psj.2025.105296_bib0024","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.cvsm.2017.10.002","article-title":"Recent advances in vaccine technologies","volume":"48","author":"Francis","year":"2018","journal-title":"Vet Clin. North Am. Small Anim. Pr."},{"key":"10.1016\/j.psj.2025.105296_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.vaccine.2024.02.050","article-title":"WITHDRAWN: PIRES2-EGFP\/CTB-UreI vaccination activated a mixed Th1\/Th2\/Th17 immune system defense towards Helicobacter pylori infection in the BALB\/c mice model","author":"Ghasemifar","year":"2024","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2025.105296_bib0026","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.jconrel.2022.01.050","article-title":"A potential delivery system based on cholera toxin: a macromolecule carrier with multiple activities","volume":"343","author":"He","year":"2022","journal-title":"J. Control Release"},{"key":"10.1016\/j.psj.2025.105296_bib0005","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.exppara.2014.04.015","article-title":"Analysis of humoral immune response and cytokines in chickens vaccinated with Eimeria brunetti apical membrane antigen-1 (EbAMA1) DNA vaccine","volume":"144","author":"Hoan","year":"2014","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.psj.2025.105296_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.exppara.2020.107901","article-title":"A potential vaccine candidate towards chicken coccidiosis mediated by recombinant Lactobacillus plantarum with surface displayed EtMIC2 protein","volume":"215","author":"Huang","year":"2020","journal-title":"Exp. Parasitol."},{"issue":"1","key":"10.1016\/j.psj.2025.105296_bib0028","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.molbiopara.2004.12.002","article-title":"Eimeria tenella microneme protein EtMIC3: identification, localisation and role in host cell infection","volume":"140","author":"Labb\u00e9","year":"2005","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.psj.2025.105296_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.fsi.2023.108659","article-title":"Oral vaccination with recombinant Lactobacillus casei with surface displayed OmpK fused to CTB as an adjuvant against Vibrio mimicus infection in Carassius auratus","volume":"135","author":"Li","year":"2023","journal-title":"Fish. Shellfish. Immunol."},{"issue":"3","key":"10.1016\/j.psj.2025.105296_bib0030","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1645\/GE-3476","article-title":"Embryo vaccination against Eimeria tenella and E. acervulina infections using recombinant proteins and cytokine adjuvants","volume":"91","author":"Lillehoj","year":"2005","journal-title":"J. Parasitol."},{"issue":"3","key":"10.1016\/j.psj.2025.105296_bib0031","doi-asserted-by":"crossref","DOI":"10.1111\/1751-7915.14447","article-title":"Recombinant production of SAG1 fused with xylanase in Pichia pastoris induced higher protective immunity against Eimeria tenella infection in chicken","volume":"17","author":"Liu","year":"2024","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.psj.2025.105296_bib0032","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1051\/parasite\/2021047","article-title":"Understanding the interactions between Eimeria infection and gut microbiota, towards the control of chicken coccidiosis: a review","volume":"28","author":"Madlala","year":"2021","journal-title":"Parasite"},{"issue":"9","key":"10.1016\/j.psj.2025.105296_bib0033","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-004709","article-title":"Peptide emulsions in incomplete Freund's adjuvant create effective nurseries promoting egress of systemic CD4(+) and CD8(+) T cells for immunotherapy of cancer","volume":"10","author":"Melssen","year":"2022","journal-title":"J. ImmunOther Cancer"},{"issue":"1-2","key":"10.1016\/j.psj.2025.105296_bib0034","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0264-410X(01)00270-5","article-title":"Adjuvant effects of IL-1beta, IL-2, IL-8, IL-15, IFN-alpha, IFN-gamma TGF-beta4 and lymphotactin on DNA vaccination against Eimeria acervulina","volume":"20","author":"Min","year":"2001","journal-title":"Vaccine"},{"key":"10.1016\/j.psj.2025.105296_bib0035","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s11250-025-04441-4","article-title":"Effects of replacing antibiotics with probiotics and antimicrobial peptides on performance, gut health, carcass traits, meat quality, and welfare in broilers infected with Eimeria and Clostridium perfringens","volume":"57","author":"Muneeb","year":"2025","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.psj.2025.105296_bib0036","doi-asserted-by":"crossref","DOI":"10.1007\/s12011-024-04399-8","article-title":"Use of metallic nanoparticles against eimeria-the coccidiosis-causing agents: a comprehensive review","author":"Mustafa","year":"2024","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2025.105296_bib0037","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/2657981","article-title":"Herbal remedies for coccidiosis control: a review of plants, compounds, and anticoccidial actions","volume":"2016","author":"Muthamilselvan","year":"2016","journal-title":"Evid Based Complement Altern. Med"},{"issue":"2","key":"10.1016\/j.psj.2025.105296_bib0006","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.ijpara.2012.10.024","article-title":"The rhoptry proteome of Eimeria tenella sporozoites","volume":"43","author":"Oakes","year":"2013","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.psj.2025.105296_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2024.122946","article-title":"Rapid and efficient immune response induced by a designed modular cholera toxin B subunit (CTB)-based self-assembling nanoparticle","volume":"315","author":"Pan","year":"2025","journal-title":"Biomaterials"},{"issue":"5","key":"10.1016\/j.psj.2025.105296_bib0039","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.vaccine.2017.12.045","article-title":"Development of an FHbp-CTB holotoxin-like chimera and the elicitation of bactericidal antibodies against serogroup B Neisseria meningitidis","volume":"36","author":"Price","year":"2018","journal-title":"Vaccine"},{"issue":"6","key":"10.1016\/j.psj.2025.105296_bib0040","doi-asserted-by":"crossref","first-page":"2281","DOI":"10.1007\/s00436-013-3389-0","article-title":"Partial protective of chickens against Eimeria tenella challenge with recombinant EtMIC-1 antigen","volume":"112","author":"Qi","year":"2013","journal-title":"Parasitol. Res."},{"issue":"6","key":"10.1016\/j.psj.2025.105296_bib0041","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1645\/GE-1558.1","article-title":"Characterization of monoclonal antibodies that recognize the Eimeria tenella microneme protein MIC2","volume":"94","author":"Sasai","year":"2008","journal-title":"J. Parasitol."},{"issue":"30","key":"10.1016\/j.psj.2025.105296_bib0042","doi-asserted-by":"crossref","first-page":"4460","DOI":"10.1016\/j.vaccine.2012.04.076","article-title":"Plant expressed coccidial antigens as potential vaccine candidates in protecting chicken against coccidiosis","volume":"30","author":"Sathish","year":"2012","journal-title":"Vaccine"},{"issue":"2","key":"10.1016\/j.psj.2025.105296_bib0007","article-title":"Genetic mapping identifies novel highly protective antigens for an apicomplexan parasite","volume":"7","author":"Sibley","year":"2011","journal-title":"PLoS Pathog."},{"issue":"3-4","key":"10.1016\/j.psj.2025.105296_bib0008","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.vetpar.2015.08.026","article-title":"Partial protection against four species of chicken coccidia induced by multivalent subunit vaccine","volume":"212","author":"Song","year":"2015","journal-title":"Vet. Parasitol."},{"issue":"3","key":"10.1016\/j.psj.2025.105296_bib0043","doi-asserted-by":"crossref","first-page":"579","DOI":"10.3390\/vaccines3030579","article-title":"Cholera toxin subunit B as adjuvant\u2013an accelerator in protective immunity and a break in autoimmunity","volume":"3","author":"Stratmann","year":"2015","journal-title":"Vaccines. (Basel)"},{"issue":"2","key":"10.1016\/j.psj.2025.105296_bib0044","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1002\/btpr.1846","article-title":"Display of heterologous proteins on the Saccharomyces cerevisiae surface display system using a single constitutive expression vector","volume":"30","author":"Sun","year":"2014","journal-title":"Biotechnol. Prog."},{"key":"10.1016\/j.psj.2025.105296_bib0045","article-title":"Bacillus subtilis spores displaying toxoplasma gondii GRA12 induce immunity against acute toxoplasmosis","volume":"16","author":"Sun","year":"2025","journal-title":"Front. Immunol."},{"key":"10.1016\/j.psj.2025.105296_bib0046","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1362289","article-title":"The cholera toxin B subunit induces trained immunity in dendritic cells and promotes CD8 T cell antitumor immunity","volume":"15","author":"Tepale-Segura","year":"2024","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.psj.2025.105296_bib0047","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S0020-7519(01)00255-7","article-title":"EtMIC4: a microneme protein from Eimeria tenella that contains tandem arrays of epidermal growth factor-like repeats and thrombospondin type-I repeats","volume":"31","author":"Tomley","year":"2001","journal-title":"Int. J. Parasitol."},{"issue":"1","key":"10.1016\/j.psj.2025.105296_bib0048","doi-asserted-by":"crossref","first-page":"4305","DOI":"10.1038\/s41598-023-30834-2","article-title":"Characterization and utility of two monoclonal antibodies to cholera toxin B subunit","volume":"13","author":"Verjan Garcia","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2025.105296_bib0049","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2025.1516944","article-title":"The Mycoplasma hyopneumoniae protein Mhp274 elicits mucosal and systemic immune responses in mice","volume":"15","author":"Xie","year":"2025","journal-title":"Front. Cell Infect. Microbiol."},{"key":"10.1016\/j.psj.2025.105296_bib0050","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1051\/parasite\/2018061","article-title":"Molecular characterization and protective efficacy of the microneme 2 protein from Eimeria tenella","volume":"25","author":"Yan","year":"2018","journal-title":"Parasite"},{"issue":"10","key":"10.1016\/j.psj.2025.105296_bib0051","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1007\/s00436-022-07612-6","article-title":"Vaccines against chicken coccidiosis with particular reference to previous decade: progress, challenges, and opportunities","volume":"121","author":"Zaheer","year":"2022","journal-title":"Parasitol. Res."},{"issue":"3-4","key":"10.1016\/j.psj.2025.105296_bib0052","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.vetpar.2012.03.025","article-title":"Eimeria tenella heat shock protein 70 enhances protection of recombinant microneme protein MIC2 subunit antigen vaccination against E. tenella challenge","volume":"188","author":"Zhang","year":"2012","journal-title":"Vet. Parasitol."},{"issue":"9","key":"10.1016\/j.psj.2025.105296_bib0054","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1007\/s00436-020-06745-w","article-title":"Immunological evaluation of invasive Lactobacillus plantarum co-expressing EtMIC2 and chicken interleukin-18 against Eimeria tenella","volume":"119","author":"Zhang","year":"2020","journal-title":"Parasitol. Res."},{"issue":"8","key":"10.1016\/j.psj.2025.105296_bib0053","doi-asserted-by":"crossref","DOI":"10.3390\/nano14080728","article-title":"Efficient production of self-assembled bioconjugate nanovaccines against Klebsiella pneumoniae O2 serotype in engineered Escherichia coli","volume":"14","author":"Zhang","year":"2024","journal-title":"Nanomaterials (Basel)"},{"issue":"1","key":"10.1016\/j.psj.2025.105296_bib0056","doi-asserted-by":"crossref","DOI":"10.1128\/Spectrum.00228-21","article-title":"Identification and characterization of Eimeria tenella microneme protein (EtMIC8)","volume":"9","author":"Zhao","year":"2021","journal-title":"Microbiol. Spectr."},{"issue":"12","key":"10.1016\/j.psj.2025.105296_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.104246","article-title":"Innovative prevention and control of coccidiosis: targeting sporogony for new control agent development","volume":"103","author":"Zhao","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.105296_bib0057","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.1042143","article-title":"Combined oral immunization with probiotics entercoccus faecalis delivering surface-anchored Eimeria tenella proteins provide protective efficacies against homologous infection in chickens","volume":"13","author":"Zhi","year":"2022","journal-title":"Front. Immunol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125005383?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125005383?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T14:45:35Z","timestamp":1756305935000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125005383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":57,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S0032579125005383"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.105296","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fusion with CTB enhances the immunogenicity and protective efficacy of MIC2 subunit vaccine against Eimeria tenella","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.105296","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"105296"}}