{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:48:20Z","timestamp":1786996100649,"version":"build-2736575974"},"reference-count":40,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T00:00:00Z","timestamp":1749081600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012438","name":"Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System","doi-asserted-by":"publisher","award":["SCCXTD-2020-18"],"award-info":[{"award-number":["SCCXTD-2020-18"]}],"id":[{"id":"10.13039\/501100012438","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011798","name":"Ministry of Agriculture and Rural Affairs of the People's Republic of China","doi-asserted-by":"publisher","award":["CARS-42-17"],"award-info":[{"award-number":["CARS-42-17"]}],"id":[{"id":"10.13039\/501100011798","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.psj.2025.105399","type":"journal-article","created":{"date-parts":[[2025,6,6]],"date-time":"2025-06-06T02:38:55Z","timestamp":1749177535000},"page":"105399","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Duck plague virus gG is secreted, nonstructural glycoprotein, not essential for viral replication and responsible for the virulence"],"prefix":"10.1016","volume":"104","author":[{"given":"Jie","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingshu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6093-353X","authenticated-orcid":false,"given":"Anchun","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xumin","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Di","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaqiu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"XinXin","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dekang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renyong","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mafeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2025.105399_bib0001","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s11262-011-0677-6","article-title":"vitro characterization of EHV-4 gG-deleted mutant","volume":"44","author":"AZAB","year":"2012","journal-title":"Virus Genes [J],"},{"key":"10.1016\/j.psj.2025.105399_bib0002","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.immuni.2023.04.004","article-title":"The Spleen in Local and Systemic Regulation of Immunity","volume":"56","author":"BRONTE","year":"2023","journal-title":"Immunity [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0003","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1093\/emboj\/cdg092","article-title":"Glycoprotein G isoforms from some alphaherpesviruses function as broad-spectrum chemokine binding proteins","volume":"22","author":"BRYANT","year":"2003","journal-title":"Embo j [J],"},{"key":"10.1016\/j.psj.2025.105399_bib0004","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1038\/s41423-023-00974-6","article-title":"The chemokines CXCL8 and CXCL12: molecular and functional properties, role in disease and efforts towards pharmacological intervention","volume":"20","author":"CAMBIER","year":"2023","journal-title":"Cell Mol Immunol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0005","doi-asserted-by":"crossref","first-page":"3084","DOI":"10.1096\/fj.201700013R","article-title":"Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric modulation of CXCR4","volume":"31","author":"COLLINS P","year":"2017","journal-title":"Faseb j [J],"},{"key":"10.1016\/j.psj.2025.105399_bib0006","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/s41579-020-00448-w","article-title":"The structural basis of herpesvirus entry","volume":"19","author":"CONNOLLY","year":"2021","journal-title":"Nat Rev Microbiol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0007","first-page":"92","article-title":"Infectious Laryngotracheitis Virus Viral Chemokine-Binding Protein Glycoprotein G Alters Transcription of Key Inflammatory Mediators In Vitro and In Vivo","author":"COPPO","year":"2018","journal-title":"J Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0008","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1099\/vir.0.81388-0","article-title":"Both soluble and membrane-anchored forms of Felid herpesvirus 1 glycoprotein G function as a broad-spectrum chemokine-binding protein","volume":"86","author":"COSTES","year":"2005","journal-title":"J Gen Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0009","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1016\/j.micinf.2006.07.014","article-title":"Felid herpesvirus 1 glycoprotein G is a structural protein that mediates the binding of chemokines on the viral envelope","volume":"8","author":"COSTES","year":"2006","journal-title":"Microbes Infect [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0010","doi-asserted-by":"crossref","first-page":"10856","DOI":"10.1128\/JVI.75.22.10856-10869.2001","article-title":"Insertions in the gG gene of pseudorabies virus reduce expression of the upstream Us3 protein and inhibit cell-to-cell spread of virus infection","volume":"75","author":"DEMMIN","year":"2001","journal-title":"J Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0011","doi-asserted-by":"crossref","first-page":"2839","DOI":"10.1099\/vir.0.82194-0","article-title":"Glycoprotein G is a virulence factor in infectious laryngotracheitis virus","volume":"87","author":"DEVLIN","year":"2006","journal-title":"J Gen Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0012","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.vaccine.2009.11.013","article-title":"Evaluation of immunological responses to a glycoprotein G deficient candidate vaccine strain of infectious laryngotracheitis virus","volume":"28","author":"DEVLIN","year":"2010","journal-title":"Vaccine [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0013","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1080\/01652176.2017.1298885","article-title":"Duck virus enteritis (duck plague) - a comprehensive update","volume":"37","author":"DHAMA","year":"2017","journal-title":"Vet Q [J]"},{"issue":"Pt 5","key":"10.1016\/j.psj.2025.105399_bib0014","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1099\/0022-1317-79-5-1205","article-title":"Equine herpesvirus-4 glycoprotein G is secreted as a disulphide-linked homodimer and is present as two homodimeric species in the virion","volume":"79","author":"DRUMMER","year":"1998","journal-title":"J Gen Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0015","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.cytogfr.2016.02.007","article-title":"Chemokine binding proteins: An immunomodulatory strategy going viral","volume":"30","author":"GONZ\u00c1LEZ-MOTOS","year":"2016","journal-title":"Cytokine Growth Factor Rev [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0016","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12985-018-0928-4","article-title":"Molecular characterization of duck enteritis virus UL41 protein","volume":"15","author":"HE","year":"2018","journal-title":"Virol J [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0017","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1186\/s13567-020-00859-w","article-title":"Duck enteritis virus pUL47, as a late structural protein localized in the nucleus, mainly depends on residues 40 to 50 and 768 to 777 and inhibits IFN-\u03b2 signalling by interacting with STAT1","volume":"51","author":"HE","year":"2020","journal-title":"Vet Res [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0018","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1099\/vir.0.82532-0","article-title":"Identification of transcripts and protein products of the UL31, UL37, UL46, UL47, UL48, UL49 and US4 gene homologues of avian infectious laryngotracheitis virus","volume":"88","author":"HELFERICH","year":"2007","journal-title":"J Gen Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0019","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1099\/vir.0.82533-0","article-title":"The UL47 gene of avian infectious laryngotracheitis virus is not essential for in vitro replication but is relevant for virulence in chickens","volume":"88","author":"HELFERICH","year":"2007","journal-title":"J Gen Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0020","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/cmi.2017.107","article-title":"The unique structural and functional features of CXCL12","volume":"15","author":"JANSSENS","year":"2018","journal-title":"Cell Mol Immunol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0021","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.3389\/fimmu.2019.01008","article-title":"Bovine Herpesvirus 1 Counteracts Immune Responses and Immune-Surveillance to Enhance Pathogenesis and Virus Transmission","volume":"10","author":"JONES","year":"2019","journal-title":"Front Immunol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0022","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1891\/0730-0832.34.5.279","article-title":"Herpes Simplex Virus: Beyond the Basics","volume":"34","author":"KOBTY","year":"2015","journal-title":"Neonatal Netw [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0023","article-title":"Duck plague virus infection alter the microbiota composition and intestinal functional activity in Muscovy ducks","volume":"102","author":"KONG","year":"2023","journal-title":"Poult Sci [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0024","first-page":"12","article-title":"Identification of the Cleavage Domain within Glycoprotein G of Herpes Simplex Virus Type 2","author":"KROPP","year":"2020","journal-title":"Viruses [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0025","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3389\/fcimb.2019.00463","article-title":"Duplicate US1 Genes of Duck Enteritis Virus Encode a Non-essential Immediate Early Protein Localized to the Nucleus","volume":"9","author":"LI","year":"2019","journal-title":"Front Cell Infect Microbiol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0026","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s00705-023-05727-4","article-title":"Equid herpesvirus type 3 infection produces membrane-associated and secreted forms of glycoprotein G that are not required for efficient cell-to-cell spread of the virus in vitro","volume":"168","author":"LOSINNO","year":"2023","journal-title":"Arch Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0027","doi-asserted-by":"crossref","first-page":"3007","DOI":"10.1099\/jgv.0.000616","article-title":"Herpes simplex virus particles interact with chemokines and enhance cell migration","volume":"97","author":"MART\u00cdNEZ-MART\u00cdN","year":"2016","journal-title":"J Gen Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0028","doi-asserted-by":"crossref","first-page":"5084","DOI":"10.3390\/v7092861","article-title":"Tegument Assembly and Secondary Envelopment of Alphaherpesviruses","volume":"7","author":"OWEN","year":"2015","journal-title":"Viruses [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0029","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1128\/jvi.57.2.647-655.1986","article-title":"Identification of a new glycoprotein of herpes simplex virus type 1 and genetic mapping of the gene that codes for it","volume":"57","author":"RICHMAN","year":"1986","journal-title":"J Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0030","article-title":"Characterization of a Unique Novel LORF3 Protein of Duck Plague Virus and Its Potential Pathogenesis","volume":"97","author":"SHEN","year":"2023","journal-title":"J Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0031","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1128\/jvi.61.5.1735-1737.1987","article-title":"Processing of the herpes simplex virus type 2 glycoprotein gG-2 results in secretion of a 34,000-Mr cleavage product","volume":"61","author":"SU","year":"1987","journal-title":"J Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0032","doi-asserted-by":"crossref","first-page":"6090","DOI":"10.1128\/JVI.00098-08","article-title":"Alphaherpesviruses and chemokines: pas de deux not yet brought to perfection","volume":"82","author":"VAN DE WALLE","year":"2008","journal-title":"J Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0033","doi-asserted-by":"crossref","first-page":"4161","DOI":"10.4049\/jimmunol.179.6.4161","article-title":"Herpesvirus chemokine-binding glycoprotein G (gG) efficiently inhibits neutrophil chemotaxis in vitro and in vivo","volume":"179","author":"VAN DE WALLE","year":"2007","journal-title":"J Immunol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0034","article-title":"Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses","volume":"8","author":"VIEJO-BORBOLLA","year":"2012","journal-title":"PLoS Pathog [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0035","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1099\/vir.0.011940-0","article-title":"Glycoprotein G from pseudorabies virus binds to chemokines with high affinity and inhibits their function","volume":"91","author":"VIEJO-BORBOLLA","year":"2010","journal-title":"J Gen Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0036","doi-asserted-by":"crossref","first-page":"5965","DOI":"10.1128\/JVI.00529-12","article-title":"Complete genomic sequence of Chinese virulent duck enteritis virus","volume":"86","author":"WU","year":"2012","journal-title":"J Virol [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0037","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12985-017-0748-y","article-title":"Preliminary study of the UL55 gene based on infectious Chinese virulent duck enteritis virus bacterial artificial chromosome clone","volume":"14","author":"WU","year":"2017","journal-title":"Virol J [J]"},{"key":"10.1016\/j.psj.2025.105399_bib0038","series-title":"[C]\/\/2010 3rd International Conference on Biomedical Engineering and Informatics","first-page":"2159","article-title":"Bioinformatics analysis and characteristics of glycoprotein G encoded by the newly identified Us4 gene of duck enteritis virus","author":"YANG","year":"2010"},{"key":"10.1016\/j.psj.2025.105399_bib0039","series-title":"[C]\/\/2010 3rd International Conference on Biomedical Engineering and Informatics","first-page":"2221","article-title":"Molecular cloning and sequence analysis of the duck enteritis virus Us4 gene","author":"YANG","year":"2010"},{"key":"10.1016\/j.psj.2025.105399_bib0040","doi-asserted-by":"crossref","first-page":"369","DOI":"10.17219\/acem\/58802","article-title":"The Thymus: A Forgotten, But Very Important Organ","volume":"25","author":"ZDROJEWICZ","year":"2016","journal-title":"Adv Clin Exp Med [J],"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003257912500642X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S003257912500642X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T02:54:57Z","timestamp":1756436097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S003257912500642X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["S003257912500642X"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.105399","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Duck plague virus gG is secreted, nonstructural glycoprotein, not essential for viral replication and responsible for the virulence","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.105399","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"105399"}}