{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:50:34Z","timestamp":1777711834649,"version":"3.51.4"},"reference-count":52,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019415","name":"H Wilhelm Schaumann Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019415","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023561","name":"Government of Spain Ministry of Universities","doi-asserted-by":"publisher","award":["RD 289\/2021"],"award-info":[{"award-number":["RD 289\/2021"]}],"id":[{"id":"10.13039\/501100023561","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["UP2021-035"],"award-info":[{"award-number":["UP2021-035"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.psj.2025.105517","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T12:16:35Z","timestamp":1751544995000},"page":"105517","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Influence of Pleurotus sapidus fruiting bodies on the performance, cecal microbiome, and gene expression in the liver and breast muscle of broilers"],"prefix":"10.1016","volume":"104","author":[{"given":"Lea","family":"Sch\u00e4fer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2958-2422","authenticated-orcid":false,"given":"Sarah M.","family":"Grundmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verena","family":"Hepp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4243-1717","authenticated-orcid":false,"given":"Javier","family":"Herrero-Encinas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"R\u00fchl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erika","family":"Most","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1321-4820","authenticated-orcid":false,"given":"Robert","family":"Ringseis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Eder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2025.105517_bib0001","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s40093-019-00317-4","article-title":"Upcycling of food industry side streams by basidiomycetes for production of a vegan protein source","volume":"8","author":"Ahlborn","year":"2019","journal-title":"Int. J. Recycl. Org. Waste Agricult."},{"key":"10.1016\/j.psj.2025.105517_bib0002","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2024.121978","article-title":"An overview on mushroom polysaccharides: health-promoting properties, prebiotic and gut microbiota modulation effects and structure-function correlation","volume":"333","author":"Ara\u00fajo-Rodrigues","year":"2024","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.psj.2025.105517_bib0003","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s13668-023-00468-x","article-title":"Nutritional quality and biological application of mushroom protein as a novel protein alternative","volume":"12","author":"Ayimbila","year":"2023","journal-title":"Curr. Nutr. Rep."},{"key":"10.1016\/j.psj.2025.105517_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.103635","article-title":"Effect of replacing soybean meal with Hermetia illucens meal on cecal microbiota, liver transcriptome and plasma metabolome of broilers","volume":"103","author":"Beller","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0005","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1038\/s41587-019-0209-9","article-title":"Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2","volume":"37","author":"Bolyen","year":"2019","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.psj.2025.105517_bib0006","doi-asserted-by":"crossref","first-page":"6689","DOI":"10.3168\/jds.2016-12406","article-title":"Effect of endoplasmic reticulum stress on metabolic and stress signaling and kidney-specific functions in Madin-Darby bovine kidney cells","volume":"100","author":"Chiappisi","year":"2017","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0007","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.3390\/ani13132236","article-title":"Characterization of \u03b2-glucans from cereal and microbial sources and their roles in feeds for intestinal health and growth of nursery pigs","volume":"13","author":"Choi","year":"2023","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.psj.2025.105517_bib0008","unstructured":"Cobb-Vantress. Cobb 500 broiler performance & nutrition supplement 2022."},{"key":"10.1016\/j.psj.2025.105517_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2021.104543","article-title":"\u03b2-glucan release from fungal and plant cell walls after simulated gastrointestinal digestion","volume":"83","author":"Colosimo","year":"2021","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.psj.2025.105517_bib0010","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.tifs.2021.02.001","article-title":"Comparison of the behavior of fungal and plant cell wall during gastrointestinal digestion and resulting health effects: a review","volume":"110","author":"Colosimo","year":"2021","journal-title":"Trends Food Sci. Technol."},{"key":"10.1016\/j.psj.2025.105517_bib0011","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1017\/S0043933909000294","article-title":"Phytate and microbial phytase: implications for endogenous nitrogen losses and nutrient availability","volume":"65","author":"Cowieson","year":"2009","journal-title":"World\u2019s Poult. Sci. J."},{"key":"10.1016\/j.psj.2025.105517_bib0012","first-page":"992","volume":"63","author":"De Oliveira Silva","year":"2015"},{"key":"10.1016\/j.psj.2025.105517_bib0013","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1093\/nar\/30.1.207","article-title":"Gene Expression Omnibus: NCBI gene expression and hybridization array data repository","volume":"30","author":"Edgar","year":"2002","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.psj.2025.105517_bib0014","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0149820","article-title":"Prawn shell chitosan exhibits anti-obesogenic potential through alterations to appetite, affecting feeding behaviour and satiety signals In Vivo","volume":"11","author":"Egan","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.psj.2025.105517_bib0016","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1186\/s12917-014-0196-5","article-title":"Effects of dietary polyphenol-rich plant products from grape or hop on pro-inflammatory gene expression in the intestine, nutrient digestibility and faecal microbiota of weaned pigs","volume":"10","author":"Fiesel","year":"2014","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.psj.2025.105517_bib0017","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.2527\/jas1989.6751293x","article-title":"Effect of pelleting and beta-glucanase supplementation on the ileal and fecal digestibility of a barley-based diet in the pig","volume":"67","author":"Graham","year":"1989","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0018","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang","year":"2009","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.psj.2025.105517_bib0019","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/j.foodchem.2007.10.015","article-title":"Extraction yield of isoflavones from soybean meal as affected by solvent and supercritical carbon dioxide","volume":"107","author":"Kao","year":"2008","journal-title":"Food Chem"},{"key":"10.1016\/j.psj.2025.105517_bib0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/fib8010001","article-title":"Structural features, modification, and functionalities of beta-glucan","volume":"8","author":"Kaur","year":"2019","journal-title":"Fibers"},{"key":"10.1016\/j.psj.2025.105517_bib0021","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1002\/pmic.200800571","article-title":"Plasma proteome analysis for anti-obesity and anti-diabetic potentials of chitosan oligosaccharides in ob\/ob mice","volume":"9","author":"Kumar","year":"2009","journal-title":"Proteomics"},{"key":"10.1016\/j.psj.2025.105517_bib0022","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.3382\/ps\/pev114","article-title":"Poultry enteric inflammation model with dextran sodium sulfate mediated chemical induction and feed restriction in broilers","volume":"94","author":"Kuttappan","year":"2015","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0023","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.202000591","article-title":"Characterization of the nutritional composition of a biotechnologically produced oyster mushroom and its physiological effects in obese Zucker rats","volume":"64","author":"Maheshwari","year":"2020","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.psj.2025.105517_bib0024","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/nrendo.2017.56","article-title":"Hepatokines: linking nonalcoholic fatty liver disease and insulin resistance","volume":"13","author":"Meex","year":"2017","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.psj.2025.105517_bib0025","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201801305","article-title":"The antisteatotic and hypolipidemic effect of insect meal in obese Zucker rats is accompanied by profound changes in hepatic phospholipid and 1-carbon metabolism","volume":"63","author":"Meyer","year":"2019","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.psj.2025.105517_bib0026","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s40694-020-00095-z","article-title":"Growing a circular economy with fungal biotechnology: a white paper","volume":"7","author":"Meyer","year":"2020","journal-title":"Fungal Biol. Biotechnol."},{"key":"10.1016\/j.psj.2025.105517_bib0027","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.129492","article-title":"The hepatokine Tsukushi is released in response to NAFLD and impacts cholesterol homeostasis","volume":"4","author":"Mouchiroud","year":"2019","journal-title":"JCI Insight"},{"key":"10.1016\/j.psj.2025.105517_bib0028","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.foodchem.2017.09.149","article-title":"Anti-inflammatory properties of edible mushrooms: a review","volume":"243","author":"Muszy\u0144ska","year":"2018","journal-title":"Food Chem."},{"key":"10.1016\/j.psj.2025.105517_bib0029","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.foodchem.2010.12.149","article-title":"A new colorimetric method to quantify \u03b2-1,3-1,6-glucans in comparison with total \u03b2-1,3-glucans in edible mushrooms","volume":"127","author":"Nitschke","year":"2011","journal-title":"Food Chem."},{"key":"10.1016\/j.psj.2025.105517_bib0030","doi-asserted-by":"crossref","unstructured":"OECD\/FAO (2024) OECD-FAO agricultural Outlook 2024-2033, Paris and Rome. URL: https:\/\/doi.org\/10.1787\/4c5d2cfb-en.","DOI":"10.1787\/4c5d2cfb-en"},{"key":"10.1016\/j.psj.2025.105517_bib0031","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1097\/PHM.0b013e31822dea3c","article-title":"Joint inflammation alters gene and protein expression and leads to atrophy in the tibialis anterior muscle in rats","volume":"90","author":"Ram\u00edrez","year":"2011","journal-title":"Am. J. Phys. Med. Rehabil."},{"key":"10.1016\/j.psj.2025.105517_bib0032","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1079\/BJN19940029","article-title":"Effect of chitin and chitosan on nutrient digestibility and plasma lipid concentrations in broiler chickens","volume":"72","author":"Razdan","year":"1994","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.psj.2025.105517_bib0033","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/s40104-022-00783-3","article-title":"Heat stress in pigs and broilers: role of gut dysbiosis in the impairment of the gut-liver axis and restoration of these effects by probiotics, prebiotics and synbiotics","volume":"13","author":"Ringseis","year":"2022","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2025.105517_bib0034","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1146\/annurev-animal-021419-083852","article-title":"The gut-liver axis in the control of energy metabolism and food intake in animals","volume":"8","author":"Ringseis","year":"2020","journal-title":"Annu. Rev. Anim. Biosci."},{"key":"10.1016\/j.psj.2025.105517_bib0035","series-title":"Wood Production, Wood Technology, and Biotechnological Impacts","first-page":"555","article-title":"Mushroom production","author":"R\u00fchl","year":"2007"},{"key":"10.1016\/j.psj.2025.105517_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.103975","article-title":"Effects of a biotechnologically produced Pleurotus sapidus mycelium on gut microbiome, liver transcriptome and plasma metabolome of broilers","volume":"103","author":"Sch\u00e4fer","year":"2024","journal-title":"Poult Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.104450","article-title":"Research note: effect of a biotechnologically produced Pleurotus sapidus mycelium on expression of genes involved in protein synthesis and degradation in breast muscle of broilers","volume":"103","author":"Sch\u00e4fer","year":"2024","journal-title":"Poult Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0038","doi-asserted-by":"crossref","first-page":"3560","DOI":"10.3390\/molecules26123560","article-title":"Review: \u03b2-glucans as effective antibiotic alternatives in poultry","volume":"26","author":"Schwartz","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.psj.2025.105517_bib0039","doi-asserted-by":"crossref","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.psj.2025.105517_bib0040","doi-asserted-by":"crossref","first-page":"181","DOI":"10.3390\/ani11010181","article-title":"Effects of dietary fiber on nutrients utilization and gut health of poultry: a review of challenges and opportunities","volume":"11","author":"Singh","year":"2021","journal-title":"Animals"},{"key":"10.1016\/j.psj.2025.105517_bib0041","series-title":"Food Composition and Nutrition Tables. 8th Revised and Completed Edition - 8., Revidierte und Erg\u00e4nzte Auflage - 8e \u00c9dition, Revue Et Compl\u00e9t\u00e9e","author":"Souci","year":"2016"},{"key":"10.1016\/j.psj.2025.105517_bib0042","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.3390\/molecules26071832","article-title":"On the identification and quantification of ergothioneine and lovastatin in various mushroom species: assets and challenges of different analytical approaches","volume":"26","author":"Tsiantas","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.psj.2025.105517_bib0043","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/376387","article-title":"Edible mushrooms: improving human health and promoting quality life","volume":"2015","author":"Valverde","year":"2015","journal-title":"Int. J. Microbiol."},{"key":"10.1016\/j.psj.2025.105517_bib0044","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-7-research0034","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","author":"Vandesompele","year":"2002","journal-title":"Genome Biol."},{"key":"10.1016\/j.psj.2025.105517_bib0045","series-title":"Die Chemische Untersuchung von Futtermitteln. Dritte Auflage","year":"2012"},{"key":"10.1016\/j.psj.2025.105517_bib0046","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.3382\/ps\/pev111","article-title":"Dose titration of FITC-D for optimal measurement of enteric inflammation in broiler chicks","volume":"94","author":"Vicu\u00f1a","year":"2015","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0047","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053828","article-title":"Multi-functional roles of Chitosan as a potential protective agent against obesity","volume":"8","author":"Walsh","year":"2013","journal-title":"Plos One"},{"key":"10.1016\/j.psj.2025.105517_bib0048","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1093\/jn\/122.11.2292","article-title":"Barley beta-glucans alter intestinal viscosity and reduce plasma cholesterol concentrations in chicks","volume":"122","author":"Wang","year":"1992","journal-title":"J. Nutr."},{"key":"10.1016\/j.psj.2025.105517_bib0049","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/s42255-018-0020-9","article-title":"The hepatokine tsukushi gates energy expenditure via brown fat sympathetic innervation","volume":"1","author":"Wang","year":"2019","journal-title":"Nat. Metab."},{"key":"10.1016\/j.psj.2025.105517_bib0050","article-title":"Genome-wide association study and selective sweep analysis reveal the genetic architecture of body weights in a chicken f2 resource population","volume":"9","author":"Wang","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0051","first-page":"181","article-title":"The prediction of apparent metabolizable energy values for poultry in compound feeds","volume":"40","year":"1984","journal-title":"World\u2019s Poult. Sci. J."},{"key":"10.1016\/j.psj.2025.105517_bib0052","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/nyas.12500","article-title":"Production and supply of high-quality food protein for human consumption: sustainability, challenges, and innovations","volume":"1321","author":"Wu","year":"2014","journal-title":"Ann. New York Acad. Sci."},{"key":"10.1016\/j.psj.2025.105517_bib0053","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1073\/pnas.2637002100","article-title":"Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41","volume":"101","author":"Xiong","year":"2004","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125007606?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125007606?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T10:03:07Z","timestamp":1777456987000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125007606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":52,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0032579125007606"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.105517","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of Pleurotus sapidus fruiting bodies on the performance, cecal microbiome, and gene expression in the liver and breast muscle of broilers","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.105517","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"105517"}}