{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,11]],"date-time":"2026-01-11T11:59:52Z","timestamp":1768132792631,"version":"3.49.0"},"reference-count":53,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T00:00:00Z","timestamp":1751414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32360827-31760663"],"award-info":[{"award-number":["32360827-31760663"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.psj.2025.105520","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T22:22:42Z","timestamp":1751581362000},"page":"105520","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["The inositol 1,4,5-trisphosphate receptor type 2 protein domains regulate calcium levels and Ion transport gene expression in laying ducks' uterus"],"prefix":"10.1016","volume":"104","author":[{"given":"Yong","family":"Zhao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guanghui","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmei","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yijie","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingchen","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-4611-4704","authenticated-orcid":false,"given":"Yiyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2025.105520_bib0001","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/00019606-200603000-00009","article-title":"Validation of the 2(-Delta Delta Ct) calculation as an alternate method of data analysis for quantitative pcr of bcr-Abl P210 transcripts","volume":"15","author":"Arocho","year":"2006","journal-title":"Diagn. Mol. Pathol."},{"issue":"6410","key":"10.1016\/j.psj.2025.105520_bib0002","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1038\/361315a0","article-title":"Inositol trisphosphate and calcium signalling","volume":"361","author":"Berridge","year":"1993","journal-title":"Nature"},{"issue":"7","key":"10.1016\/j.psj.2025.105520_bib0003","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1038\/nrm1155","article-title":"Calcium signalling: dynamics, homeostasis and remodelling","volume":"4","author":"Berridge","year":"2003","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"11","key":"10.1016\/j.psj.2025.105520_bib0004","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1161\/HYPERTENSIONAHA.121.18513","article-title":"Rare variants in genes encoding subunits of the epithelial Na(+) channel are associated with blood pressure and kidney function","volume":"79","author":"Blobner","year":"2022","journal-title":"Hypertension"},{"key":"10.1016\/j.psj.2025.105520_bib0005","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1186\/1471-2164-15-220","article-title":"Hen uterine gene expression profiling during eggshell formation reveals putative proteins involved in the supply of minerals or in the shell mineralization process","volume":"15","author":"Brionne","year":"2014","journal-title":"BMC Genom."},{"issue":"8","key":"10.1016\/j.psj.2025.105520_bib0006","doi-asserted-by":"crossref","first-page":"a3947","DOI":"10.1101\/cshperspect.a003947","article-title":"Voltage-gated calcium channels","volume":"3","author":"Catterall","year":"2011","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"5626","key":"10.1016\/j.psj.2025.105520_bib0007","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1126\/science.1085371","article-title":"Evolution of the protein repertoire","volume":"300","author":"Chothia","year":"2003","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0008","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0014-5793(01)03289-6","article-title":"Protein domain analysis in the era of complete genomes","volume":"513","author":"Copley","year":"2002","journal-title":"FEBS. Lett."},{"key":"10.1016\/j.psj.2025.105520_bib0009","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2023.1215645","article-title":"Characterization of the TRPV6 calcium channel-specific phenotype by RNA-seq in castration-resistant human prostate cancer cells","volume":"14","author":"Cordier","year":"2023","journal-title":"Front. Genet."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0010","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.abb.2008.02.026","article-title":"The plasma membrane Ca2+ ATPase of animal cells: structure, function and regulation","volume":"476","author":"Di Leva","year":"2008","journal-title":"Arch. Biochem. Biophys."},{"issue":"3","key":"10.1016\/j.psj.2025.105520_bib0011","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1095\/biolreprod19.3.493","article-title":"On the control of calcium secretion in the avian shell gland (uterus)","volume":"19","author":"Eastin","year":"1978","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.psj.2025.105520_bib0012","first-page":"2","article-title":"Protein structural domains: definition and prediction","volume":"2","author":"Ezkurdia","year":"2011","journal-title":"Curr. Protoc. Protein Sci."},{"key":"10.1016\/j.psj.2025.105520_bib0013","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.aninu.2023.03.004","article-title":"Uterine inflammation status modulates eggshell mineralization via calcium transport and matrix protein synthesis in laying hens","volume":"13","author":"Feng","year":"2023","journal-title":"Anim. Nutr."},{"issue":"11","key":"10.1016\/j.psj.2025.105520_bib0014","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1038\/nrm2272","article-title":"Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology","volume":"8","author":"Forgac","year":"2007","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0015","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s40104-023-00986-2","article-title":"Decreased eggshell strength caused by impairment of uterine calcium transport coincide with higher bone minerals and quality in aged laying hens","volume":"15","author":"Fu","year":"2024","journal-title":"J. Anim. Sci. Biotechnol."},{"issue":"5744","key":"10.1016\/j.psj.2025.105520_bib0016","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1126\/science.1114110","article-title":"IP3 receptor types 2 and 3 mediate exocrine secretion underlying energy metabolism","volume":"309","author":"Futatsugi","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.psj.2025.105520_bib0017","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.aninu.2024.04.026","article-title":"Methionine supplementation regulates eggshell quality and uterine transcriptome in late-stage broiler breeders","volume":"19","author":"Gao","year":"2024","journal-title":"Anim. Nutr."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0018","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12860-021-00350-0","article-title":"Avian eggshell biomineralization: an update on its structure, mineralogy and protein tool kit","volume":"22","author":"Gautron","year":"2021","journal-title":"BMC Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0019","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1152\/physrev.00021.2009","article-title":"Inwardly rectifying potassium channels: their structure, function, and physiological roles","volume":"90","author":"Hibino","year":"2010","journal-title":"Physiol. Rev."},{"issue":"4","key":"10.1016\/j.psj.2025.105520_bib0020","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1053\/gast.2002.32363","article-title":"The type II inositol 1,4,5-trisphosphate receptor can trigger Ca2+ waves in rat hepatocytes","volume":"122","author":"Hirata","year":"2002","journal-title":"Gastroenterology"},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0021","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1152\/physrev.00003.2004","article-title":"Calcium absorption across epithelia","volume":"85","author":"Hoenderop","year":"2005","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.psj.2025.105520_bib0022","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1146\/annurev.immunol.021908.132550","article-title":"Molecular basis of calcium signaling in lymphocytes: STIM and ORAI","volume":"28","author":"Hogan","year":"2010","journal-title":"Annu. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.psj.2025.105520_bib0023","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0099205","article-title":"Mice lacking inositol 1,4,5-trisphosphate receptors exhibit dry eye","volume":"9","author":"Inaba","year":"2014","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.psj.2025.105520_bib0024","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1080\/15548627.2020.1732161","article-title":"TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium","volume":"17","author":"Kim","year":"2021","journal-title":"Autophagy"},{"issue":"5","key":"10.1016\/j.psj.2025.105520_bib0025","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1002\/hep.24548","article-title":"Type 2 inositol 1,4,5-trisphosphate receptor modulates bile salt export pump activity in rat hepatocytes","volume":"54","author":"Kruglov","year":"2011","journal-title":"Hepatology"},{"issue":"Pt 1","key":"10.1016\/j.psj.2025.105520_bib0026","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1042\/BJ20051094","article-title":"The forkhead transcription factor Foxi1 directly activates the AE4 promoter","volume":"393","author":"Kurth","year":"2006","journal-title":"Biochem. J."},{"issue":"11","key":"10.1016\/j.psj.2025.105520_bib0027","doi-asserted-by":"crossref","first-page":"a3996","DOI":"10.1101\/cshperspect.a003996","article-title":"Ryanodine receptors: structure, expression, molecular details, and function in calcium release","volume":"2","author":"Lanner","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0028","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0896-6273(91)90120-O","article-title":"Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons","volume":"6","author":"Mattson","year":"1991","journal-title":"Neuron"},{"issue":"182","key":"10.1016\/j.psj.2025.105520_bib0029","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2021.0502","article-title":"How much calcium to shell out? Eggshell calcium carbonate content is greater in birds with thinner shells, larger clutches and longer lifespans","volume":"18","author":"McClelland","year":"2021","journal-title":"J. R. Soc. Interface"},{"key":"10.1016\/j.psj.2025.105520_bib0030","article-title":"Use of fluo-3 to measure cytosolic Ca-2+ in platelets and neutrophils - loading cells with the dye, calibration of traces, measurements in the presence of plasma, and buffering of cytosolic Ca-2+","volume":"269","author":"Merritt","year":"1990","journal-title":"Biochem. J."},{"issue":"2","key":"10.1016\/j.psj.2025.105520_bib0031","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/nrm729","article-title":"The vacuolar (H+)-ATPases-nature's most versatile proton pumps","volume":"3","author":"Nishi","year":"2002","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0032","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/glia.23531","article-title":"Inositol 1,4,5-trisphosphate receptor type 2-independent Ca (2+) release from the endoplasmic reticulum in astrocytes","volume":"67","author":"Okubo","year":"2019","journal-title":"Glia"},{"issue":"26","key":"10.1016\/j.psj.2025.105520_bib0033","doi-asserted-by":"crossref","first-page":"18776","DOI":"10.1016\/S0021-9258(19)37028-0","article-title":"Isolation, characterization, and localization of the inositol 1,4,5-trisphosphate receptor protein in Xenopus laevis oocytes","volume":"267","author":"Parys","year":"1992","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.psj.2025.105520_bib0034","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/ar.1092160203","article-title":"Calcium-binding protein (28,000 Mr calbindin-D28k) in kidneys of the bullfrog Rana catesbeiana during metamorphosis","volume":"216","author":"Rhoten","year":"1986","journal-title":"Anat. Rec. (Hoboken)"},{"issue":"11","key":"10.1016\/j.psj.2025.105520_bib53","doi-asserted-by":"crossref","first-page":"4316","DOI":"10.1172\/JCI84937","article-title":"Calcium release channel RyR2 regulates insulin release and glucose homeostasis","volume":"125","author":"Santulli","year":"2015","journal-title":"J. Clin. Invest."},{"issue":"3","key":"10.1016\/j.psj.2025.105520_bib0035","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1002\/humu.9266","article-title":"Carbonic anhydrase II deficiency syndrome (osteopetrosis with renal tubular acidosis and brain calcification): novel mutations in CA2 identified by direct sequencing expand the opportunity for genotype-phenotype correlation","volume":"24","author":"Shah","year":"2004","journal-title":"Hum. Mutat."},{"issue":"4","key":"10.1016\/j.psj.2025.105520_bib0036","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1016\/S0016-5085(03)01201-0","article-title":"Loss of inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis","volume":"125","author":"Shibao","year":"2003","journal-title":"Gastroenterology"},{"issue":"4","key":"10.1016\/j.psj.2025.105520_bib0037","first-page":"283","article-title":"Plasma membrane Ca2+ pumps and Na+\/Ca2+ exchangers","volume":"1","author":"Strehler","year":"1990","journal-title":"Semin Cell Biol"},{"key":"10.1016\/j.psj.2025.105520_bib0038","doi-asserted-by":"crossref","DOI":"10.1186\/s12864-015-1795-7","article-title":"Genome-wide association study revealed a promising region and candidate genes for eggshell quality in an F2 resource population","volume":"16","author":"Sun","year":"2015","journal-title":"BMC Genomics"},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0039","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1249\/JES.0000000000000348","article-title":"Intracellular Ca 2+ after eccentric muscle contractions: key role for ryanodine receptors","volume":"53","author":"Tabuchi","year":"2025","journal-title":"Exerc. Sport Sci. Rev."},{"issue":"12","key":"10.1016\/j.psj.2025.105520_bib0040","doi-asserted-by":"crossref","first-page":"a4010","DOI":"10.1101\/cshperspect.a004010","article-title":"IP(3) receptors: toward understanding their activation","volume":"2","author":"Taylor","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"13","key":"10.1016\/j.psj.2025.105520_bib0041","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1096\/fasebj.10.13.8940296","article-title":"Spatial and temporal aspects of cellular calcium signaling","volume":"10","author":"Thomas","year":"1996","journal-title":"FASEB J."},{"issue":"16","key":"10.1016\/j.psj.2025.105520_bib0042","doi-asserted-by":"crossref","DOI":"10.3390\/nano13162299","article-title":"Hydrothermal transformation of eggshell calcium carbonate into apatite micro-nanoparticles: cytocompatibility and osteoinductive properties","volume":"13","author":"Torres-Mansilla","year":"2023","journal-title":"Nanomaterials"},{"issue":"9","key":"10.1016\/j.psj.2025.105520_bib0043","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1016\/j.bbamcr.2014.12.006","article-title":"The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca(2)(+)-release channel","volume":"1853","author":"Vervloessem","year":"2015","journal-title":"Biochim. Biophys. Acta."},{"issue":"3","key":"10.1016\/j.psj.2025.105520_bib0044","first-page":"lqad84","article-title":"Most protein domains exist as variants with distinct functions across cells, tissues and diseases","volume":"5","author":"Vitting-Seerup","year":"2023","journal-title":"NAR Genom. Bioinform."},{"issue":"11","key":"10.1016\/j.psj.2025.105520_bib0045","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1113\/JP271140","article-title":"Proteolytic fragmentation of inositol 1,4,5-trisphosphate receptors: a novel mechanism regulating channel activity?","volume":"594","author":"Wang","year":"2016","journal-title":"J. Physiol."},{"issue":"4","key":"10.1016\/j.psj.2025.105520_bib0046","doi-asserted-by":"crossref","first-page":"C1242","DOI":"10.1152\/ajpcell.00106.2002","article-title":"Inhibition of muscle carbonic anhydrase slows the Ca(2+) transient in rat skeletal muscle fibers","volume":"283","author":"Wetzel","year":"2002","journal-title":"Am. J. Physiol. Cell Physiol."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0047","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1152\/physrev.00033.2020","article-title":"Calcium-release channels: structure and function of IP(3) receptors and ryanodine receptors","volume":"102","author":"Woll","year":"2022","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.psj.2025.105520_bib0048","doi-asserted-by":"crossref","first-page":"e72559","DOI":"10.7554\/eLife.72559","article-title":"Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder","volume":"10","author":"Wu","year":"2021","journal-title":"Elife"},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0049","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1186\/s12917-022-03387-1","article-title":"Correlation analysis of serum reproductive hormones and metabolites during multiple ovulation in sheep","volume":"18","author":"Xu","year":"2022","journal-title":"BMC Vet. Res."},{"issue":"1","key":"10.1016\/j.psj.2025.105520_bib0050","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1186\/s12864-019-6017-2","article-title":"The differences of gonadal hormones and uterine transcriptome during shell calcification of hens laying hard or weak-shelled eggs","volume":"20","author":"Zhang","year":"2019","journal-title":"BMC Genom."},{"issue":"14","key":"10.1016\/j.psj.2025.105520_bib0051","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202316777","article-title":"Sortase-catalyzed protein domain inversion","volume":"63","author":"Zhou","year":"2024","journal-title":"Angew. Chem. Int. Ed."},{"issue":"Pt 2","key":"10.1016\/j.psj.2025.105520_bib0052","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1113\/jphysiol.2007.140731","article-title":"IP3-dependent nuclear Ca2+ signalling in the mammalian heart","volume":"584","author":"Zima","year":"2007","journal-title":"J. Physiol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125007631?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125007631?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T05:53:16Z","timestamp":1759211596000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125007631"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":53,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0032579125007631"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.105520","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The inositol 1,4,5-trisphosphate receptor type 2 protein domains regulate calcium levels and Ion transport gene expression in laying ducks' uterus","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.105520","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"105520"}}