{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T16:57:42Z","timestamp":1776963462261,"version":"3.51.4"},"reference-count":25,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T00:00:00Z","timestamp":1758499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2023AFB354"],"award-info":[{"award-number":["2023AFB354"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.psj.2025.105886","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T07:50:58Z","timestamp":1758613858000},"page":"105886","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Dietary supplementary with soya saponins alleviates the poor intestinal health of broilers challenged with coccidia via reshaping the structure of the intestinal microbiota"],"prefix":"10.1016","volume":"104","author":[{"given":"Peng","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaochen","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhui","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengjun","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuangshuang","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bingying","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongqing","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1086","key":"10.1016\/j.psj.2025.105886_bib0001","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1136\/postgradmedj-2015-133715","article-title":"Evaluation of abnormal liver function tests","volume":"92","author":"Agrawal","year":"2016","journal-title":"Postgr. Med. J."},{"issue":"2","key":"10.1016\/j.psj.2025.105886_bib0002","doi-asserted-by":"crossref","first-page":"325","DOI":"10.5194\/aab-63-325-2020","article-title":"Physiological, antimicrobial, intestine morphological, and immunological effects of fructooligosaccharides in pigs","volume":"63","author":"Csernus","year":"2020","journal-title":"Arch. Anim. Breed."},{"issue":"1","key":"10.1016\/j.psj.2025.105886_bib0003","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2420765","article-title":"How important are fatty acids in human health and can they be used in treating diseases?","volume":"16","author":"Dicks","year":"2024","journal-title":"Gut. Microbes."},{"issue":"4","key":"10.1016\/j.psj.2025.105886_bib0004","doi-asserted-by":"crossref","first-page":"3459","DOI":"10.3892\/mmr.2016.4978","article-title":"Impaired function of the intestinal barrier in a novel sub-health rat model","volume":"13","author":"Feng","year":"2016","journal-title":"Mol. Med. Rep."},{"issue":"11","key":"10.1016\/j.psj.2025.105886_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.103018","article-title":"Evaluating a Salmonella Typhimurium, Eimeria maxima, and Clostridium perfringens coinfection necrotic enteritis model in broiler chickens: repeatability, dosing, and immune outcomes","volume":"102","author":"Fries-Craft","year":"2023","journal-title":"Poult. Sci."},{"issue":"7","key":"10.1016\/j.psj.2025.105886_bib0006","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.jnutbio.2009.11.007","article-title":"Statistics and bioinformatics in nutritional sciences: analysis of complex data in the era of systems biology","volume":"21","author":"Fu","year":"2010","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.psj.2025.105886_bib0007","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.fsi.2018.04.004","article-title":"Soya-saponins induce intestinal inflammation and barrier dysfunction in juvenile turbot (Scophthalmus maximus)","volume":"77","author":"Gu","year":"2018","journal-title":"Fish. Shellfish. Immunol."},{"issue":"22","key":"10.1016\/j.psj.2025.105886_bib0008","doi-asserted-by":"crossref","DOI":"10.3390\/ijms222212394","article-title":"Uric acid in inflammation and the pathogenesis of atherosclerosis","volume":"22","author":"Kimura","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.psj.2025.105886_bib0009","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/nyas.14798","article-title":"Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival","volume":"1514","author":"Kuo","year":"2022","journal-title":"Ann. N Acad. Sci."},{"key":"10.1016\/j.psj.2025.105886_bib0010","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.1025677","article-title":"Dietary Lactobacillus fermentum and Lactobacillus paracasei improve the intestinal health of broilers challenged with coccidia and Clostridium perfringens","volume":"9","author":"Li","year":"2022","journal-title":"Front. Vet. Sci."},{"issue":"8","key":"10.1016\/j.psj.2025.105886_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.101921","article-title":"Soya saponin fails to improve the antioxidation and immune function of laying hens with antibiotics treated","volume":"101","author":"Li","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.105886_bib0012","article-title":"Fecal microbiota transplantation reshapes the physiological function of the intestine in antibiotic-treated specific pathogen-free birds","volume":"13","author":"Li","year":"2022","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.psj.2025.105886_bib0013","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101663","article-title":"Dietary soya saponin improves the lipid metabolism and intestinal health of laying hens","volume":"101","author":"Li","year":"2022","journal-title":"Poult. Sci."},{"issue":"12","key":"10.1016\/j.psj.2025.105886_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.104429","article-title":"Dietary supplementary with ellagic acid improves the intestinal barrier function and microbiota structure of broiler chicken challenged with E. coli K88","volume":"103","author":"Li","year":"2024","journal-title":"Poult. Sci."},{"issue":"1","key":"10.1016\/j.psj.2025.105886_bib0015","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/s40104-021-00647-2","article-title":"Soya saponin improves egg-laying performance and immune function of laying hens","volume":"12","author":"Li","year":"2022","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2025.105886_bib26","doi-asserted-by":"crossref","first-page":"1082500","DOI":"10.3389\/fnut.2022.1082500","article-title":"The relationship between nutrition and the immune system","volume":"9","author":"Munteanu","year":"2022","journal-title":"Front. Nutr."},{"issue":"1","key":"10.1016\/j.psj.2025.105886_bib0016","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s11259-023-10199-7","article-title":"Protective effects of feed additives on broiler chickens exposed to aflatoxins-contaminated feed: a systematic review and meta-analysis","volume":"48","author":"Putra","year":"2024","journal-title":"Vet. Res. Commun."},{"issue":"4","key":"10.1016\/j.psj.2025.105886_bib0017","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1093\/jas\/sky036","article-title":"Immunomodulatory potential of dietary soybean-derived isoflavones and saponins in pigs","volume":"96","author":"Smith","year":"2018","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2025.105886_bib0018","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.aninu.2024.05.009","article-title":"Dietary sanguinarine supplementation improves the growth performance and intestinal immunity of broilers","volume":"19","author":"Su","year":"2024","journal-title":"Anim. Nutr."},{"issue":"4","key":"10.1016\/j.psj.2025.105886_bib0019","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.101746","article-title":"Quantifying the effect of coccidiosis on broiler performance and infection outcomes in the presence and absence of control methods","volume":"101","author":"Taylor","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.105886_bib0020","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/bs.vh.2021.06.009","article-title":"Blood glucose regulation in context of infection","volume":"117","author":"Wensveen","year":"2021","journal-title":"Vitam. Horm."},{"key":"10.1016\/j.psj.2025.105886_bib0021","doi-asserted-by":"crossref","first-page":"skae349","DOI":"10.1093\/jas\/skae349","article-title":"Immunomodulatory potential of dietary soybean-derived saponins","volume":"102","author":"White","year":"2024","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2025.105886_bib0022","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.coph.2021.11.001","article-title":"The regulatory roles of dietary fibers on host health via gut microbiota-derived short chain fatty acids","volume":"62","author":"Xu","year":"2022","journal-title":"Curr. Opin. Pharmacol."},{"issue":"48","key":"10.1016\/j.psj.2025.105886_bib0023","doi-asserted-by":"crossref","first-page":"14387","DOI":"10.1021\/acs.jafc.1c04819","article-title":"Bridging the gaps between plant and human health: a systematic review of soyasaponins","volume":"69","author":"Yates","year":"2021","journal-title":"J. Agric. Food Chem."},{"issue":"10","key":"10.1016\/j.psj.2025.105886_bib0024","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1007\/s00436-022-07612-6","article-title":"Vaccines against chicken coccidiosis with particular reference to previous decade: progress, challenges, and opportunities","volume":"121","author":"Zaheer","year":"2022","journal-title":"Parasitol. Res."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125011277?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125011277?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T11:43:56Z","timestamp":1765539836000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125011277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":25,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S0032579125011277"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.105886","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dietary supplementary with soya saponins alleviates the poor intestinal health of broilers challenged with coccidia via reshaping the structure of the intestinal microbiota","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.105886","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"105886"}}