{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:13:03Z","timestamp":1792671183475,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:00:00Z","timestamp":1760659200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","award":["2021YFYZ0031"],"award-info":[{"award-number":["2021YFYZ0031"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.psj.2025.105977","type":"journal-article","created":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T14:12:13Z","timestamp":1760796733000},"page":"105977","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Integrated lipidomics and transcriptomics to elucidate heterogeneity between intramuscular and abdominal fat and identify serum and liver markers for their differential deposition in chickens"],"prefix":"10.1016","volume":"104","author":[{"given":"Zhongzhen","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6537-268X","authenticated-orcid":false,"given":"Chaowu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingqian","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunlin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2554-3269","authenticated-orcid":false,"given":"Yiping","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2025.105977_bib0001","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/nn.4201","article-title":"Astrocyte calcium signaling: the third wave","volume":"19","author":"Bazargani","year":"2016","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.psj.2025.105977_bib0002","doi-asserted-by":"crossref","first-page":"5229","DOI":"10.1021\/jf063372l","article-title":"New indicators of beef sensory quality revealed by expression of specific genes","volume":"55","author":"Bernard","year":"2007","journal-title":"J. Agric. Food. Chem"},{"key":"10.1016\/j.psj.2025.105977_bib0003","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1079\/PNS19750007","article-title":"Lipid metabolism in the fowl under normal and abnormal circumstances","volume":"34","author":"Butler","year":"1975","journal-title":"Proc. Nutr. Soc."},{"key":"10.1016\/j.psj.2025.105977_bib0004","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.meatsci.2017.05.001","article-title":"Selection for intramuscular fat and lean meat yield will improve the bloomed colour of Australian lamb loin meat","volume":"131","author":"Calnan","year":"2017","journal-title":"Meat. Sci"},{"key":"10.1016\/j.psj.2025.105977_bib0005","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1186\/s12864-024-10537-2","article-title":"ALKBH5 regulates chicken adipogenesis by mediating LCAT mRNA stability depending on m6A modification","volume":"25","author":"Chao","year":"2024","journal-title":"Bmc. Genom."},{"key":"10.1016\/j.psj.2025.105977_bib0006","doi-asserted-by":"crossref","first-page":"3479","DOI":"10.1007\/s11033-011-1120-8","article-title":"Liver dominant expression of fatty acid synthase (FAS) gene in two chicken breeds during intramuscular-fat development","volume":"39","author":"Cui","year":"2012","journal-title":"Mol. Biol. Rep"},{"key":"10.1016\/j.psj.2025.105977_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.jfca.2022.105082","article-title":"Antibiotic residues in chicken meat in China: occurrence and cumulative health risk assessment","volume":"116","author":"Fei","year":"2023","journal-title":"J. Food. Compos. Anal."},{"key":"10.1016\/j.psj.2025.105977_bib0008","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.5713\/ajas.2013.13702","article-title":"Nutritional factors affecting abdominal fat deposition in poultry: a review","volume":"27","author":"Fouad","year":"2014","journal-title":"Asian. Australas. J. Anim. Sci"},{"key":"10.1016\/j.psj.2025.105977_bib0009","doi-asserted-by":"crossref","first-page":"699","DOI":"10.5851\/kosfa.2016.36.6.699","article-title":"Consumer acceptability of intramuscular fat","volume":"36","author":"Frank","year":"2016","journal-title":"Korean. J. Food. Sci. Anim. Resour"},{"key":"10.1016\/j.psj.2025.105977_bib0010","doi-asserted-by":"crossref","first-page":"3649","DOI":"10.1039\/D1FO03391C","article-title":"Dihydromyricetin improves meat quality and promotes skeletal muscle fiber type transformations via AMPK signaling in growing-finishing pigs","volume":"13","author":"Guo","year":"2022","journal-title":"Food. Funct"},{"key":"10.1016\/j.psj.2025.105977_bib0011","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/nrm3311","article-title":"AMPK: a nutrient and energy sensor that maintains energy homeostasis","volume":"13","author":"Hardie","year":"2012","journal-title":"Nat. Rev. Mol. Cell. Biol."},{"key":"10.1016\/j.psj.2025.105977_bib0012","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4161\/adip.28546","article-title":"Intermuscular and intramuscular adipose tissues: bad vs. good adipose tissues","volume":"3","author":"Hausman","year":"2014","journal-title":"Adipocyte"},{"key":"10.1016\/j.psj.2025.105977_bib0013","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1017\/S1751731109991091","article-title":"Intramuscular fat content in meat-producing animals: development, genetic and nutritional control, and identification of putative markers","volume":"4","author":"Hocquette","year":"2010","journal-title":"Animal"},{"key":"10.1016\/j.psj.2025.105977_bib0014","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1111\/jbg.12204","article-title":"Selection against abdominal fat percentage may increase intramuscular fat content in broilers","volume":"133","author":"Leng","year":"2016","journal-title":"J. Anim. Breed. Genet"},{"key":"10.1016\/j.psj.2025.105977_bib0015","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.3382\/ps.0541075","article-title":"Lipid biosynthesis in the chick. A consideration of site of synthesis, influence of diet and possible regulatory mechanisms","volume":"54","author":"Leveille","year":"1975","journal-title":"Poult. Sci"},{"key":"10.1016\/j.psj.2025.105977_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2022.113611","article-title":"LC\/MS-based lipidomics to characterize breed-specific and tissue-specific lipid composition of chicken meat and abdominal fat","volume":"163","author":"Li","year":"2022","journal-title":"LWT-Food. Sci. Technol"},{"key":"10.1016\/j.psj.2025.105977_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2022.111171","article-title":"Integration analysis of metabolome and transcriptome profiles revealed the age-dependent dynamic change in chicken meat","volume":"156","author":"Li","year":"2022","journal-title":"Food. Res. Int."},{"key":"10.1016\/j.psj.2025.105977_bib0018","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1017\/S175173111900209X","article-title":"Review: enhancing intramuscular fat development via targeting fibro-adipogenic progenitor cells in meat animals","volume":"14","author":"Li","year":"2020","journal-title":"Animal"},{"key":"10.1016\/j.psj.2025.105977_bib0019","doi-asserted-by":"crossref","first-page":"12910","DOI":"10.1021\/acs.jafc.3c03178","article-title":"Lipid deposition and progesterone synthesis are increased by miR-181b-5p through RAP1B\/ERK1\/2 pathway in chicken granulosa cells","volume":"71","author":"Lin","year":"2023","journal-title":"J. Agric. Food. Chem"},{"key":"10.1016\/j.psj.2025.105977_bib0020","doi-asserted-by":"crossref","first-page":"635","DOI":"10.3390\/genes13040635","article-title":"miR-24-3p dominates the proliferation and differentiation of chicken intramuscular preadipocytes by blocking ANXA6 expression","volume":"13","author":"Lin","year":"2022","journal-title":"Genes"},{"key":"10.1016\/j.psj.2025.105977_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102900","article-title":"Age-associated changes in the growth development of abdominal fat and their correlations with cecal gut microbiota in broiler chickens","volume":"102","author":"Liu","year":"2023","journal-title":"Poult. Sci"},{"key":"10.1016\/j.psj.2025.105977_bib0022","doi-asserted-by":"crossref","first-page":"134805","DOI":"10.1016\/j.foodchem.2022.134805","article-title":"A proteomic approach to identify biomarkers of foal meat quality: a focus on tenderness, color and intramuscular fat traits","volume":"405","author":"Lopez-Pedrouso","year":"2023","journal-title":"Food. Chem"},{"key":"10.1016\/j.psj.2025.105977_bib0023","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1186\/s12864-022-08538-0","article-title":"Differential regulation of intramuscular fat and abdominal fat deposition in chickens","volume":"23","author":"Luo","year":"2022","journal-title":"Bmc. Genom."},{"key":"10.1016\/j.psj.2025.105977_bib0024","doi-asserted-by":"crossref","first-page":"414","DOI":"10.3390\/genes12030414","article-title":"Molecular regulation of lipogenesis, adipogenesis and fat deposition in chicken","volume":"12","author":"Nematbakhsh","year":"2021","journal-title":"Genes"},{"key":"10.1016\/j.psj.2025.105977_bib0025","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1038\/s43587-023-00521-y","article-title":"Refeeding-associated AMPK\u03b31 complex activity is a hallmark of health and longevity","volume":"3","author":"Ripa","year":"2023","journal-title":"Nat. Aging"},{"key":"10.1016\/j.psj.2025.105977_bib0026","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.782268","article-title":"Chromatin interaction responds to breast muscle development and intramuscular fat deposition between Chinese indigenous chicken and fast-growing broiler","volume":"9","author":"Tian","year":"2021","journal-title":"Front. Cell. Dev. Biol."},{"key":"10.1016\/j.psj.2025.105977_bib0027","doi-asserted-by":"crossref","first-page":"1030485","DOI":"10.3389\/fnut.2022.1030485","article-title":"Lactobacillus improves meat quality in Sunit sheep by affecting mitochondrial biogenesis through the AMPK pathway","volume":"9","author":"Wang","year":"2022","journal-title":"Front. Nutr"},{"key":"10.1016\/j.psj.2025.105977_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2023.113083","article-title":"Integrated LC\/MS-based lipidomics and transcriptomics analyses revealed lipid composition heterogeneity between pectoralis intramuscular fat and abdominal fat and its regulatory mechanism in chicken","volume":"172","author":"Wang","year":"2023","journal-title":"Food. Res. Int."},{"key":"10.1016\/j.psj.2025.105977_bib0029","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1248\/bpb.b17-00724","article-title":"AMPK-mediated regulation of lipid metabolism by phosphorylation","volume":"41","author":"Wang","year":"2018","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.psj.2025.105977_bib0030","article-title":"Effects of dietary supplementation of fermented Artemisia argyi on growth performance, slaughter performance, and meat quality in broilers","volume":"103","author":"Wang","year":"2024","journal-title":"Poult. Sci"},{"key":"10.1016\/j.psj.2025.105977_bib0031","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.meatsci.2007.07.019","article-title":"Fat deposition, fatty acid composition and meat quality: a review","volume":"78","author":"Wood","year":"2008","journal-title":"Meat. Sci"},{"key":"10.1016\/j.psj.2025.105977_bib0032","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1186\/s12864-019-6116-0","article-title":"Identification of differentially expressed genes and pathways between intramuscular and abdominal fat-derived preadipocyte differentiation of chickens in vitro","volume":"20","author":"Zhang","year":"2019","journal-title":"Bmc. Genom."},{"key":"10.1016\/j.psj.2025.105977_bib0033","doi-asserted-by":"crossref","first-page":"893","DOI":"10.3390\/ani12070893","article-title":"Intramuscular fat selection in rabbits modifies the fatty acid composition of muscle and liver tissues","volume":"12","author":"Zubiri-Gaitan","year":"2022","journal-title":"Animals"},{"key":"10.1016\/j.psj.2025.105977_bib0034","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1038\/s42003-023-05266-3","article-title":"Plasma metabolomic profiling in two rabbit lines divergently selected for intramuscular fat content","volume":"6","author":"Zubiri-Gaitan","year":"2023","journal-title":"Commun. Biol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125012180?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125012180?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T20:42:41Z","timestamp":1776458561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125012180"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":34,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0032579125012180"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.105977","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Integrated lipidomics and transcriptomics to elucidate heterogeneity between intramuscular and abdominal fat and identify serum and liver markers for their differential deposition in chickens","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.105977","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"105977"}}