{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T22:36:40Z","timestamp":1780612600929,"version":"3.54.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004481","name":"University of Tehran","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004481","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.psj.2025.106058","type":"journal-article","created":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T22:57:32Z","timestamp":1762124252000},"page":"106058","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Central injection of epidermal growth factor (EGF) induces hypophagia via D\u2081 dopaminergic and \u03b2\u2082 adrenergic receptors in broiler chickens"],"prefix":"10.1016","volume":"104","author":[{"given":"Zahra","family":"Jafari-Ardakan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8252-9423","authenticated-orcid":false,"given":"Morteza","family":"Zendehdel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8023-8251","authenticated-orcid":false,"given":"Kimia","family":"Mahdavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2025.106058_bib0001","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s00359-010-0507-7","article-title":"Intralateral hypothalamic area injection of isoproterenol and propranolol affects food and water intake in broilers","volume":"196","author":"Baghbanzadeh","year":"2010","journal-title":"J. Comp. Physiol. A."},{"key":"10.1016\/j.psj.2025.106058_bib0002","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/s00213-008-1390-6","article-title":"Involvement of dopamine and opioids in the motivation to eat: influence of palatability, homeostatic state, and behavioral paradigms","volume":"203","author":"Barbano","year":"2009","journal-title":"Psychopharmacology"},{"issue":"1\u20132","key":"10.1016\/j.psj.2025.106058_bib0003","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0091-3057(01)00659-1","article-title":"DMSO as a vehicle for central injections: tests with feeding elicited by norepinephrine injected into the paraventricular nucleus","volume":"71","author":"Blevins","year":"2002","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.psj.2025.106058_bib0004","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.20892\/j.issn.2095-3941.2022.0540","article-title":"Targeting the EGF receptor family in non-small cell lung cancer\u2014Increased complexity and future perspectives","volume":"19","author":"Boch","year":"2022","journal-title":"Cancer Biol. Med."},{"key":"10.1016\/j.psj.2025.106058_bib0005","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0006-8993(99)01299-8","article-title":"Induction of food intake by a noradrenergic system using clonidine and fusaric acid in the neonatal chick","volume":"826","author":"Bungo","year":"1999","journal-title":"Brain Res."},{"key":"10.1016\/j.psj.2025.106058_bib0006","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1080\/08977190903137736","article-title":"Acute and chronic adrenergic stimulation of submandibular salivary glands. Effects on the endocrine function of epidermal growth factor in mice","volume":"27","author":"Campreci\u00f3s","year":"2009","journal-title":"Growth Factors"},{"key":"10.1016\/j.psj.2025.106058_bib0007","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1152\/physrev.00030.2015","article-title":"Expression and function of the epidermal growth factor receptor in physiology and disease","volume":"96","author":"Chen","year":"2016","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.psj.2025.106058_bib0008","doi-asserted-by":"crossref","first-page":"2446","DOI":"10.1016\/j.ajpath.2018.07.016","article-title":"Heparin-binding epidermal growth factor\u2013like growth factor as a critical mediator of tissue repair and regeneration","volume":"188","author":"Dao","year":"2018","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.psj.2025.106058_bib0009","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/0031-9384(79)90233-6","article-title":"Autoradiographic distribution of L-proline in chicks after intracerebral injection","volume":"22","author":"Davis","year":"1979","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.psj.2025.106058_bib0010","doi-asserted-by":"crossref","DOI":"10.1111\/jne.13133","article-title":"An appetite for growth: the role of the hypothalamic\u2013pituitary\u2013growth hormone axis in energy balance","volume":"34","author":"Dumbell","year":"2022","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.psj.2025.106058_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2024.115383","article-title":"Interaction between central cholecystokinin and dopaminergic system in layer-type chickens' food intake","volume":"480","author":"Ebrahimnejad","year":"2025","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.psj.2025.106058_bib0012","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0014-2999(97)01391-5","article-title":"The central corticotropin-releasing factor and glucagon-like peptide-1 in food intake of the neonatal chick","volume":"339","author":"Furuse","year":"1997","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.psj.2025.106058_bib0013","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1210\/endo.138.6.5183","article-title":"Interaction between adrenaline and epidermal growth factor in the control of liver glycogenolysis in mouse","volume":"138","author":"Grau","year":"1997","journal-title":"Endocrinology"},{"key":"10.1016\/j.psj.2025.106058_bib0014","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.yjmcc.2014.02.009","article-title":"\u03b2-adrenergic receptor-mediated transactivation of epidermal growth factor receptor decreases cardiomyocyte apoptosis through differential subcellular activation of ERK1\/2 and Akt","volume":"72","author":"Grisanti","year":"2014","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.psj.2025.106058_bib0015","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1080\/00207454.2017.1383908","article-title":"Interaction between central GABAA receptor and dopaminergic system on food intake in neonatal chicks: role of D1 and GABAA receptors","volume":"128","author":"Hashemzadeh","year":"2018","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.psj.2025.106058_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2022.101791","article-title":"Implicative role of epidermal growth factor receptor and its associated signaling partners in the pathogenesis of Alzheimer\u2019s disease","volume":"83","author":"Jayaswamy","year":"2023","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.psj.2025.106058_bib0017","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1590\/S0100-879X2011007500127","article-title":"Involvement of \u03b23-adrenergic receptors in the control of food intake in rats","volume":"44","author":"Kanzler","year":"2011","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.psj.2025.106058_bib0018","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.3390\/molecules26041076","article-title":"Molecular targeting of epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR)","volume":"26","author":"Kaufman","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.psj.2025.106058_bib0019","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1038\/nrn.2018.8","article-title":"Signalling from the periphery to the brain that regulates energy homeostasis","volume":"19","author":"Kim","year":"2018","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.psj.2025.106058_bib0020","first-page":"1970","article-title":"Chicken epidermal growth factor (EGF) receptor: cDNA cloning, expression in mouse cells, and differential binding of EGF and transforming growth factor alpha","volume":"8","author":"Lax","year":"1988","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.psj.2025.106058_bib0021","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1007\/s11259-024-10312-4","article-title":"The role of central neurotransmitters in appetite regulation of broilers and layers: similarities and differences","volume":"48","author":"Mahdavi","year":"2024","journal-title":"Vet. Res. Commun."},{"key":"10.1016\/j.psj.2025.106058_bib0022","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1097\/WNR.0b013e32834d2f65","article-title":"Dopamine stimulates epidermal growth factor release from adult neural precursor cells derived from the subventricular zone by a disintegrin and metalloprotease","volume":"22","author":"O\u2019Keeffe","year":"2011","journal-title":"Neuroreport"},{"key":"10.1016\/j.psj.2025.106058_bib0023","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0304-3940(88)90288-1","article-title":"Food intake suppression by growth factors and platelet peptides by direct action in the central nervous system","volume":"94","author":"Plata-Salam\u00e1n","year":"1988","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.psj.2025.106058_bib0024","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1146\/annurev-animal-030117-014740","article-title":"Nutrient-sensing biology in mammals and birds","volume":"6","author":"Roura","year":"2018","journal-title":"Annu. Rev. Anim. Biosci."},{"key":"10.1016\/j.psj.2025.106058_bib0025","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3390\/biom13020372","article-title":"Schizophrenia animal modeling with epidermal growth factor and its homologs: their connections to the inflammatory pathway and the dopamine system","volume":"13","author":"Sotoyama","year":"2023","journal-title":"Biomolecules"},{"key":"10.1016\/j.psj.2025.106058_bib0026","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/j.1742-4658.2009.07450.x","article-title":"EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors","volume":"277","author":"Takeuchi","year":"2010","journal-title":"FEBS J"},{"key":"10.1016\/j.psj.2025.106058_bib0027","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0899-9007(00)00415-9","article-title":"Norepinephrine and the control of food intake","volume":"16","author":"Wellman","year":"2000","journal-title":"Nutrition"},{"key":"10.1016\/j.psj.2025.106058_bib0028","doi-asserted-by":"crossref","first-page":"28435","DOI":"10.1074\/jbc.M113.461202","article-title":"Dopamine D2 receptor-mediated epidermal growth factor receptor transactivation through a disintegrin and metalloprotease regulates dopaminergic neuron development via extracellular signal-related kinase activation","volume":"288","author":"Yoon","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.psj.2025.106058_bib0031","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s12576-014-0330-y","article-title":"Ghrelin-induced hypophagia is mediated by the \u03b22 adrenergic receptor in chicken","volume":"64","author":"Zendehdel","year":"2014","journal-title":"J. Physiol. Sci."},{"key":"10.1016\/j.psj.2025.106058_bib0032","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s11259-013-9581-y","article-title":"Dopamine-induced hypophagia is mediated by D1 and 5HT-2c receptors in chicken","volume":"38","author":"Zendehdel","year":"2014","journal-title":"Vet. Res. Commun."},{"key":"10.1016\/j.psj.2025.106058_bib0033","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s10989-015-9486-4","article-title":"Interaction between opioidergic and dopaminergic systems on food intake in neonatal layer type chicken","volume":"22","author":"Zendehdel","year":"2016","journal-title":"Int. J. Pept. Res. Ther."},{"key":"10.1016\/j.psj.2025.106058_bib0034","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1080\/00071668.2017.1278626","article-title":"Serotonin-induced hypophagia is mediated via \u03b12 and \u03b22 adrenergic receptors in neonatal layer-type chickens","volume":"58","author":"Zendehdel","year":"2017","journal-title":"Br. Poult. Sci."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125013008?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125013008?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T20:37:52Z","timestamp":1776458272000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125013008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":32,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0032579125013008"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.106058","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Central injection of epidermal growth factor (EGF) induces hypophagia via D\u2081 dopaminergic and \u03b2\u2082 adrenergic receptors in broiler chickens","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.106058","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"106058"}}