{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T06:15:30Z","timestamp":1774419330296,"version":"3.50.1"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,25]],"date-time":"2025-12-25T00:00:00Z","timestamp":1766620800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011789","name":"Department of Science and Technology of Jilin Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011789","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.psj.2025.106339","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T15:59:12Z","timestamp":1766764752000},"page":"106339","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Inhibitory effect of Cnidium monnieri aqueous extract on Eimeria tenella infection in chicks"],"prefix":"10.1016","volume":"105","author":[{"given":"Yanchun","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haixia","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baihui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingjuan","family":"Lan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.psj.2025.106339_bib0001","first-page":"1927","article-title":"Effects of anticoccidial vaccination and taraxacum officinale extract on the growth performance, biochemical parameters, immunity, and intestinal morphology of Eimeria-challenged chickens","volume":"13","author":"Arczewska-W\u0142osek","year":"2023","journal-title":"Life (Basel)"},{"key":"10.1016\/j.psj.2025.106339_bib0002","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.811428","article-title":"Single and combined effects of Clostridium butyricum and coccidiosis vaccine on growth performance and the intestinal microbiome of broiler chickens","volume":"13","author":"Cai","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2025.106339_bib0003","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s13567-023-01253-y","article-title":"Protective efficacy of multiepitope vaccines constructed from common antigens of Eimeria species in chickens","volume":"54","author":"Chen","year":"2023","journal-title":"Vet. Res."},{"issue":"4","key":"10.1016\/j.psj.2025.106339_bib0004","first-page":"585","article-title":"Schisandra chinensis bee pollen ameliorates colitis in mice by modulating gut microbiota and regulating treg\/Th17 balance","volume":"13","author":"Cheng","year":"2024","journal-title":"Foods (Basel, Switzerland)"},{"issue":"3","key":"10.1016\/j.psj.2025.106339_bib0005","article-title":"Drivers of antibiotic use in semi-intensive poultry farms: evidence from a survey in Senegal","volume":"12","author":"Emes","year":"2023","journal-title":"Antibiotics. (Basel)"},{"key":"10.1016\/j.psj.2025.106339_bib0006","doi-asserted-by":"crossref","first-page":"3711","DOI":"10.1007\/s11259-024-10512-y","article-title":"Antioxidant properties of D-limonene and its nanoemulsion form enhance its anticoccidial efficiency in experimentally infected broilers with Eimeria tenella: an in vitro and in vivo study","volume":"48","author":"Ewais","year":"2024","journal-title":"Vet. Res. Commun."},{"key":"10.1016\/j.psj.2025.106339_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.103019","article-title":"Dietary alfalfa hay or lipid-soluble alfalfa extract may improve broiler growth, but fiber presence may be detrimental during Eimeria vaccine challenge","volume":"102","author":"Fries-Craft","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.vetpar.2023.110107","article-title":"Effects of natural extract from medicinal herbs on broilers experimentally infected with Eimeria tenella","volume":"327","author":"Jiang","year":"2024","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.psj.2025.106339_bib0009","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s40104-024-00995-9","article-title":"Two intestinal microbiota-derived metabolites, deoxycholic acid and butyrate, synergize to enhance host defense peptide synthesis and alleviate necrotic enteritis","volume":"15","author":"Kim","year":"2024","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2025.106339_bib0010","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13567-020-00885-8","article-title":"Activation of ChTLR15\/ChNF-\u03bab-ChNLRP3\/ChIL-1\u03b2 signaling transduction pathway mediated inflammatory responses to E. tenella infection","volume":"52","author":"Li","year":"2021","journal-title":"Vet. Res."},{"key":"10.1016\/j.psj.2025.106339_bib0011","doi-asserted-by":"crossref","first-page":"6400","DOI":"10.3382\/ps\/pez478","article-title":"Protective effects of \u03b3-irradiated Astragalus polysaccharides on intestinal development and mucosal immune function of immunosuppressed broilers","volume":"98","author":"Li","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2024.1375026","article-title":"Epidemiological investigation of coccidiosis and associated risk factors in broiler chickens immunized with live anticoccidial vaccines in China","volume":"11","author":"Liao","year":"2024","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0013","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1142\/S0192415X24500678","article-title":"Osthole, a Coumarin from Cnidium monnieri: A review on its pharmacology, pharmacokinetics, safety, and innovative drug delivery platforms","volume":"52","author":"Lin","year":"2024","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.psj.2025.106339_bib0014","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/5918587","article-title":"Baicalein restores the balance of Th17\/treg cells via aryl hydrocarbon receptor to attenuate colitis","volume":"2020","author":"Liu","year":"2020","journal-title":"Mediators. Inflamm."},{"key":"10.1016\/j.psj.2025.106339_bib0015","article-title":"Chlorogenic acid ameliorates intestinal inflammation by inhibiting NF-\u03bab and endoplasmic reticulum stress in lipopolysaccharide-challenged broilers","volume":"103","author":"Liu","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0016","doi-asserted-by":"crossref","first-page":"eadh1641","DOI":"10.1126\/scisignal.adh1641","article-title":"The NF-\u03bab signaling system in the immunopathogenesis of inflammatory bowel disease","volume":"17","author":"Mukherjee","year":"2024","journal-title":"Sci. Signal."},{"issue":"8","key":"10.1016\/j.psj.2025.106339_bib0017","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25084223","article-title":"Vasorelaxant and blood pressure-lowering effects of Cnidium monnieri fruit ethanol extract in Sprague Dawley and spontaneously hypertensive rats","volume":"25","author":"Park","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102582","article-title":"Hydroxytyrosol mitigates Mycoplasma gallisepticum-induced pulmonary injury through downregulation of the NF-\u03bab\/NLRP3\/IL-1\u03b2 signaling pathway in chicken","volume":"102","author":"Shan","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0019","first-page":"42","article-title":"Potential efficacy and mechanism of eight mild-natured and bitter-flavored TCMs based on gut microbiota: A review","volume":"16","author":"Su","year":"2024","journal-title":"Chin. Herb. Med."},{"key":"10.1016\/j.psj.2025.106339_bib0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102845","article-title":"Pathogenicity and drug resistance of the Eimeria tenella isolate from Yiwu, Zhejiang province, eastern China","volume":"102","author":"Sun","year":"2023","journal-title":"Poult. Sci."},{"issue":"3","key":"10.1016\/j.psj.2025.106339_bib0021","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21031006","article-title":"Phytochemistry, ethnopharmacology, pharmacokinetics and toxicology of Cnidium monnieri (L.) Cusson","volume":"21","author":"Sun","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0022","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/ame2.12463","article-title":"Histopathologic observations in a coccidiosis model of Eimeria tenella","volume":"7","author":"Sun","year":"2024","journal-title":"Animal. Model. Exp. Med."},{"key":"10.1016\/j.psj.2025.106339_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122612","article-title":"Gut microbiota as a key regulator of intestinal mucosal immunity","volume":"345","author":"Wang","year":"2024","journal-title":"Life Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.116879","article-title":"Traditional Chinese Medicine: A promising strategy to regulate the imbalance of bacterial flora, impaired intestinal barrier and immune function attributed to ulcerative colitis through intestinal microecology","volume":"318","author":"Wang","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.psj.2025.106339_bib0025","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/s41597-024-03523-6","article-title":"Chromosome-level genome assembly of cnidium monnieri, a highly demanded traditional Chinese medicine","volume":"11","author":"Wang","year":"2024","journal-title":"Sci. Data"},{"key":"10.1016\/j.psj.2025.106339_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155375","article-title":"Cnidii Fructus: A traditional Chinese medicine herb and source of antiosteoporotic drugs","volume":"128","author":"Xu","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.psj.2025.106339_bib0027","first-page":"181","article-title":"Chinese herbal medicines for treating ulcerative colitis via regulating gut microbiota-intestinal immunity axis","volume":"15","author":"Yang","year":"2023","journal-title":"Chin. Herb. Med."},{"key":"10.1016\/j.psj.2025.106339_bib0028","article-title":"Molecular characterization and immune protective efficacy of 3 Eimeria tenella antigens","volume":"103","author":"Zhang","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2025.106339_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.102530","article-title":"Prevention and control of chicken coccidiosis construction of recombinant lactococcus lactis expressing chicken IL-4 and IL-2 fusion protein and its immune synergistic effect on chicken coccidia live vaccine","volume":"102","author":"Zheng","year":"2023","journal-title":"Poult. Sci."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125015792?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579125015792?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T15:46:46Z","timestamp":1771861606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579125015792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S0032579125015792"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2025.106339","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibitory effect of Cnidium monnieri aqueous extract on Eimeria tenella infection in chicks","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2025.106339","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"106339"}}