{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T16:48:02Z","timestamp":1788281282387,"version":"build-2803163510"},"reference-count":41,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T00:00:00Z","timestamp":1768608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.psj.2026.106485","type":"journal-article","created":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T15:41:11Z","timestamp":1768750871000},"page":"106485","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Synergistic roles of follicle-stimulating hormone and testosterone in Sertoli cell proliferation and testicular function in roosters"],"prefix":"10.1016","volume":"105","author":[{"given":"Haishan","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuxiang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoshan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhunan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenting","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangtao","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2141-913X","authenticated-orcid":false,"given":"Guirong","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.psj.2026.106485_bib0001","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1365-2605.1987.tb00222.x","article-title":"Development of the blood-testis barrier in the domestic fowl (Gallus domesticus)","volume":"10","author":"Bergmann","year":"1987","journal-title":"Int. J. Androl"},{"key":"10.1016\/j.psj.2026.106485_bib0002","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jri.2016.06.008","article-title":"The macrophages in testis function","volume":"119","author":"Bhushan","year":"2017","journal-title":"J. Reprod. Immunol."},{"key":"10.1016\/j.psj.2026.106485_bib0003","doi-asserted-by":"crossref","first-page":"R159","DOI":"10.1530\/REP-14-0481","article-title":"Regulation of spermatogonial stem cell self-renewal and spermatocyte meiosis by Sertoli cell signaling","volume":"149","author":"Chen","year":"2015","journal-title":"Reproduction"},{"key":"10.1016\/j.psj.2026.106485_bib0004","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/978-3-319-31973-5_9","article-title":"Biology of the Sertoli cell in the fetal, pubertal, and adult mammalian testis","volume":"58","author":"Chojnacka","year":"2016","journal-title":"Results Probl. Cell Differ."},{"issue":"5","key":"10.1016\/j.psj.2026.106485_bib0005","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1194\/jlr.M025403","article-title":"FSH stimulates lipid biosynthesis in chicken adipose tissue by upregulating the expression of its receptor FSHR","volume":"53","author":"Cui","year":"2012","journal-title":"J. Lipid Res"},{"key":"10.1016\/j.psj.2026.106485_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2024.112403","article-title":"FSH increases lipid droplet content by regulating the expression of genes related to lipid storage in rat Sertoli cells","volume":"595","author":"Dasso","year":"2025","journal-title":"Mol. Cell Endocrinol."},{"key":"10.1016\/j.psj.2026.106485_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101158","article-title":"Rearing system influences the testicular development, semen quality and spermatogenic cell apoptosis of layer roosters","volume":"100","author":"Du","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106485_bib0008","doi-asserted-by":"crossref","first-page":"ozaf012","DOI":"10.1093\/mam\/ozaf012","article-title":"Dynamics of the posthatching testicular development in Japanese quail (Coturnix coturnix japonica): histological and ultrastructural study","volume":"31","author":"Eldesoky","year":"2025","journal-title":"Microsc. Microanal."},{"key":"10.1016\/j.psj.2026.106485_bib0009","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1111\/andr.12165","article-title":"The Sertoli cell: one hundred fifty years of beauty and plasticity","volume":"4","author":"Fran\u00e7a","year":"2016","journal-title":"Andrology"},{"key":"10.1016\/j.psj.2026.106485_bib0010","first-page":"35","article-title":"Regulation of germ line stem cell homeostasis","volume":"12","author":"Garcia","year":"2015","journal-title":"Anim. Reprod."},{"key":"10.1016\/j.psj.2026.106485_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2021.145531","article-title":"The role of different compounds on the integrity of blood-testis barrier: a concise review based on in vitro and in vivo studies","volume":"780","author":"Ghafouri-Fard","year":"2021","journal-title":"Gene"},{"key":"10.1016\/j.psj.2026.106485_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.852661","article-title":"The role of testosterone in spermatogenesis: lessons from proteome profiling of human spermatozoa in testosterone deficiency","volume":"13","author":"Grande","year":"2022","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"6","key":"10.1016\/j.psj.2026.106485_bib0013","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.3382\/ps.2010-01081","article-title":"Characterization of chicken sertoli cells in vitro","volume":"90","author":"Guibert","year":"2011","journal-title":"Poult Sci"},{"key":"10.1016\/j.psj.2026.106485_bib0014","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1186\/s12864-025-11944-9","article-title":"Single-cell RNA sequencing uncovers dynamic roadmap during chicken spermatogenesis","volume":"26","author":"Guo","year":"2025","journal-title":"BMC Genomics"},{"key":"10.1016\/j.psj.2026.106485_bib0015","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.mce.2008.04.012","article-title":"Gdnf signaling pathways within the mammalian spermatogonial stem cell niche","volume":"288","author":"Hofmann","year":"2008","journal-title":"Mol. Cell Endocrinol."},{"key":"10.1016\/j.psj.2026.106485_bib0016","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1095\/biolreprod.114.126326","article-title":"Processive pulses of retinoic acid propel asynchronous and continuous murine sperm production","volume":"92","author":"Hogarth","year":"2015","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.psj.2026.106485_bib0017","doi-asserted-by":"crossref","first-page":"3403","DOI":"10.1093\/humrep\/des340","article-title":"Integrity of the blood-testis barrier in healthy men after suppression of spermatogenesis with testosterone and levonorgestrel","volume":"27","author":"Ilani","year":"2012","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.psj.2026.106485_bib0018","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1210\/en.2003-1055","article-title":"Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse","volume":"145","author":"Johnston","year":"2004","journal-title":"Endocrinology"},{"key":"10.1016\/j.psj.2026.106485_bib0019","doi-asserted-by":"crossref","DOI":"10.1111\/ahe.12978","article-title":"Distributions and expressions of Aquaporin-5 and 7 in the testes of developing male chicks","volume":"53","author":"Kara","year":"2024","journal-title":"Anat. Histol. Embryol."},{"key":"10.1016\/j.psj.2026.106485_bib0020","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202100902R","article-title":"DMRT1 gene disruption alone induces incomplete gonad feminization in chicken","volume":"35","author":"Lee","year":"2021","journal-title":"FASEB J"},{"key":"10.1016\/j.psj.2026.106485_bib0021","doi-asserted-by":"crossref","first-page":"5805","DOI":"10.3390\/ijms25115805","article-title":"Hormone regulation in testicular development and function","volume":"25","author":"Li","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2026.106485_bib0022","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1055\/s-2007-991167","article-title":"Diverse FSH and testosterone signaling pathways in the Sertoli cell","volume":"39","author":"Loss","year":"2007","journal-title":"Horm. Metab. Res."},{"key":"10.1016\/j.psj.2026.106485_bib0023","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mce.2018.04.001","article-title":"Testosterone and FSH modulate Sertoli cell extracellular secretion: proteomic analysis","volume":"476","author":"Mancuso","year":"2018","journal-title":"Mol. Cell Endocrinol."},{"key":"10.1016\/j.psj.2026.106485_bib0024","first-page":"485","article-title":"Morpho-histology and morphometry of chicken testes and seminiferous tubules among yellow-feathered broilers of different ages","volume":"9","author":"Mfoundou","year":"2022","journal-title":"Vet. Sci."},{"key":"10.1016\/j.psj.2026.106485_bib0025","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/s41419-019-1782-z","article-title":"Multiple signaling pathways in Sertoli cells: recent findings in spermatogenesis","volume":"10","author":"Ni","year":"2019","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.psj.2026.106485_bib0026","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.semcdb.2021.06.016","article-title":"Sertoli cells as key drivers of testis function","volume":"121","author":"O'Donnell","year":"2022","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.psj.2026.106485_bib0027","doi-asserted-by":"crossref","first-page":"R95","DOI":"10.1530\/REP-18-0239","article-title":"Regulation of GDNF expression in Sertoli cells","volume":"157","author":"Parekh","year":"2019","journal-title":"Reproduction"},{"key":"10.1016\/j.psj.2026.106485_bib0028","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1210\/me.2012-1258","article-title":"An essential role for insulin and IGF1 receptors in regulating Sertoli cell proliferation, testis size, and FSH action in mice","volume":"27","author":"Pitetti","year":"2013","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.psj.2026.106485_bib0029","doi-asserted-by":"crossref","first-page":"R151","DOI":"10.1530\/REP-16-0588","article-title":"Role of the testis interstitial compartment in spermatogonial stem cell function","volume":"153","author":"Potter","year":"2017","journal-title":"Reproduction"},{"key":"10.1016\/j.psj.2026.106485_bib0030","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.tem.2007.09.004","article-title":"Non-classical actions of testosterone: an update","volume":"18","author":"Rahman","year":"2007","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.psj.2026.106485_bib0031","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.phymed.2017.12.036","article-title":"Berberine reinforces Sertoli cells niche and accelerates spermatogonial stem cells renewal in experimentally-induced varicocele condition in rats","volume":"40","author":"Rashtbari","year":"2018","journal-title":"Phytomedicine"},{"key":"10.1016\/j.psj.2026.106485_bib0032","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1210\/en.2017-00196","article-title":"Sertoli cell number defines and predicts germ and leydig cell population sizes in the adult mouse testis","volume":"158","author":"Rebourcet","year":"2017","journal-title":"Endocrinology"},{"key":"10.1016\/j.psj.2026.106485_bib0033","doi-asserted-by":"crossref","DOI":"10.1242\/dev.151555","article-title":"Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis","volume":"145","author":"Sharma","year":"2018","journal-title":"Development"},{"key":"10.1016\/j.psj.2026.106485_bib0034","doi-asserted-by":"crossref","first-page":"3090","DOI":"10.1016\/j.yexcr.2007.05.002","article-title":"Common and distinct factors regulate expression of mRNA for ETV5 and GDNF, sertoli cell proteins essential for spermatogonial stem cell maintenance","volume":"313","author":"Simon","year":"2007","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.psj.2026.106485_bib0035","doi-asserted-by":"crossref","first-page":"4182","DOI":"10.3382\/ps\/pez208","article-title":"Differences in semen quality, testicular histomorphology, fertility, reproductive hormone levels, and expression of candidate genes according to sperm motility in Beijing-You chickens","volume":"98","author":"Sun","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106485_bib0036","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0925-4773(02)00004-7","article-title":"Homeostatic regulation of germinal stem cell proliferation by the GDNF\/FSH pathway","volume":"113","author":"Tadokoro","year":"2002","journal-title":"Mech. Dev."},{"key":"10.1016\/j.psj.2026.106485_bib0037","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.repbio.2013.07.005","article-title":"Estradiol and testosterone inhibit rat seminiferous tubule development in a hormone-specific way","volume":"13","author":"Walczak-J\u0119drzejowska","year":"2013","journal-title":"Reprod. Biol."},{"key":"10.1016\/j.psj.2026.106485_bib0038","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1530\/rep.1.00358","article-title":"FSH and testosterone signaling in Sertoli cells","volume":"130","author":"Walker","year":"2005","journal-title":"Reproduction"},{"key":"10.1016\/j.psj.2026.106485_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2021.146112","article-title":"Boosting effect of testosterone on GDNF expression in Sertoli cell line (TM4); comparison between TM3 cells-produced and exogenous testosterone","volume":"812","author":"Zaker","year":"2022","journal-title":"Gene"},{"key":"10.1016\/j.psj.2026.106485_bib0040","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1038\/aja.2011.94","article-title":"Identification of testosterone-\/androgen receptor-regulated genes in mouse Sertoli cells","volume":"14","author":"Zhang","year":"2012","journal-title":"Asian J. Androl."},{"key":"10.1016\/j.psj.2026.106485_bib0041","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.32604\/biocell.2023.030379","article-title":"The effects of hormone-mediated PI3K\/AKT signaling on spermatogenesis in Sertoli cells","volume":"47","author":"Zhao","year":"2023","journal-title":"Biocell"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126001124?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126001124?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T07:43:22Z","timestamp":1774770202000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579126001124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":41,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S0032579126001124"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2026.106485","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synergistic roles of follicle-stimulating hormone and testosterone in Sertoli cell proliferation and testicular function in roosters","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2026.106485","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"106485"}}