{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:13:05Z","timestamp":1793193185549,"version":"4.5.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:00:00Z","timestamp":1770940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010203","name":"Agriculture Research System of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010203","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.psj.2026.106640","type":"journal-article","created":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T07:28:07Z","timestamp":1771054087000},"page":"106640","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Oligomeric ultranano hydrogen water improves flock uniformity, antioxidant capacity and intestinal health in growth phase layer-type chickens"],"prefix":"10.1016","volume":"105","author":[{"given":"Lin","family":"Dai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1415-7953","authenticated-orcid":false,"given":"Baowei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenlei","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaokun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingchen","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhigang","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanzhao","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Binghan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2026.106640_bib0001","article-title":"Qualitative assessment of groundwater for livestock and poultry watering: a case study of water wells in Hamdaniya district. Nineveh governorate","volume":"735","author":"Al-Saffawi","year":"2021","journal-title":"Iraq. IOP Conf. Ser. Earth Environ. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0002","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s10096-020-04075-4","article-title":"Bloodstream infection due to herbaspirillum sp.: case series and review of literature","volume":"40","author":"Bloise","year":"2021","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis."},{"key":"10.1016\/j.psj.2026.106640_bib0003","doi-asserted-by":"crossref","first-page":"156","DOI":"10.3390\/antiox7110156","article-title":"Superoxide dismutases (SODs) and SOD mimetics","volume":"7","author":"Borgstahl","year":"2018","journal-title":"Antioxidants"},{"key":"10.1016\/j.psj.2026.106640_bib0004","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/jsfa.8494","article-title":"Effects of dietary supplementation of red pepper (Schinus terebinthifolius Raddi) essential oil on performance, small intestinal morphology and microbial counts of weanling pigs","volume":"98","author":"Cairo","year":"2018","journal-title":"J. Sci. Food Agric."},{"key":"10.1016\/j.psj.2026.106640_bib0005","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2025.1678499","article-title":"Effects of bitter almond on production performance, antioxidant capacity and immune function of Rongde black-feathered small-sized layer strain","volume":"12","author":"Chen","year":"2025","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0006","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.3382\/ps\/pey090","article-title":"Effect of dietary non-phytate phosphorus levels on the diversity and structure of cecal microbiota in meat duck from 1 to 21 d of age","volume":"97","author":"Dai","year":"2018","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0007","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.1022783","article-title":"Early life microbiota transplantation from highly feed-efficient broiler improved weight gain by reshaping the gut microbiota in laying chicken","volume":"13","author":"Elokil","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psj.2026.106640_bib0009","doi-asserted-by":"crossref","first-page":"2230","DOI":"10.1016\/j.jid.2019.03.1165","article-title":"Molecular hydrogen protects human melanocytes from oxidative stress by activating Nrf2 signaling","volume":"140","author":"Fang","year":"2020","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.psj.2026.106640_bib43","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.cplett.2010.07.100","article-title":"Lifetime of low-density water domains in salt solutions by time-resolved Delayed Luminescence","volume":"497","author":"Gulino","year":"2010","journal-title":"Chem. Phys. Lett."},{"key":"10.1016\/j.psj.2026.106640_bib0010","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2024.1515092","article-title":"Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer\u2019s disease: targeting oxidative stress, inflammation, and the gut-brain axis","volume":"16","author":"He","year":"2025","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.psj.2026.106640_bib0011","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.3390\/nano15151193","article-title":"Effects of ultrafine bubble water on gut microbiota composition and health markers in rats","volume":"15","author":"Jackowetz","year":"2025","journal-title":"Nanomaterials"},{"key":"10.1016\/j.psj.2026.106640_bib0012","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s40104-019-0320-2","article-title":"Morphological and molecular response of small intestine to lactulose and hydrogen-rich water in female piglets fed fusarium mycotoxins contaminated diet","volume":"10","author":"Ji","year":"2019","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2026.106640_bib0013","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.aninu.2024.04.029","article-title":"Dietary supplementation with 25-hydroxyvitamin D3 regulates productive performance, lipid metabolism and gut microbiota in aged laying ducks","volume":"19","author":"Jin","year":"2024","journal-title":"Anim. Nutr."},{"key":"10.1016\/j.psj.2026.106640_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2025.105550","article-title":"Enhancing key broiler welfare indicators, meat quality, and gut microbiome composition using oxygen-enriched drinking water under commercially relevant housing conditions","volume":"104","author":"Khattak","year":"2025","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0015","first-page":"298","article-title":"Identifying risk factors for eggshell contamination by Bacillus cereus group bacteria in French laying farms","volume":"54","author":"Kone","year":"2013","journal-title":"Br. Poult. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0016","doi-asserted-by":"crossref","first-page":"869","DOI":"10.5713\/ab.21.0318","article-title":"Bacillus amyloliquefaciens and saccharomyces cerevisiae feed supplements improve growth performance and gut mucosal architecture with modulations on cecal microbiota in red-feathered native chickens","volume":"35","author":"Lee","year":"2022","journal-title":"Anim. Biosci."},{"key":"10.1016\/j.psj.2026.106640_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.104244","article-title":"Metabolomic analysis reveals altered amino acid metabolism and mechanisms underlying Eimeria infection in laying hens","volume":"103","author":"Lee","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2025.106009","article-title":"Effects of hydrogen-rich hypochlorous acid water on broiler drinking water bacterial level, growth performance, antioxidant capacity, and intestinal environment","volume":"104","author":"Li","year":"2025","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0019","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.3390\/antiox12061245","article-title":"Hydrogen-rich water ameliorates metabolic disorder via modifying gut microbiota in impaired fasting glucose patients: a randomized controlled study","volume":"12","author":"Liang","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.psj.2026.106640_bib0020","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.aninu.2021.09.012","article-title":"The interaction among gut microbes, the intestinal barrier and short chain fatty acids","volume":"9","author":"Ma","year":"2022","journal-title":"Anim. Nutr."},{"key":"10.1016\/j.psj.2026.106640_bib0021","doi-asserted-by":"crossref","first-page":"4093","DOI":"10.3390\/ijms21114093","article-title":"Fatty acid diets: regulation of gut microbiota composition and obesity and its related metabolic dysbiosis","volume":"21","author":"Machate","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0022","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/s41577-024-01014-8","article-title":"Short-chain fatty acids: linking diet, the microbiome and immunity","volume":"24","author":"Mann","year":"2024","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.psj.2026.106640_bib0023","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0377-8401(03)00163-9","article-title":"A review of interactions between dietary fibre and the intestinal mucosa, and their consequences on digestive health in young non-ruminant animals","volume":"108","author":"Montagne","year":"2003","journal-title":"Anim. Feed Sci. Technol."},{"key":"10.1016\/j.psj.2026.106640_bib44","doi-asserted-by":"crossref","first-page":"164002","DOI":"10.1088\/1361-648X\/ac5198","article-title":"Molecular dynamics simulations of structural and dynamical aspects of DNA hydration water","volume":"34","author":"Netz","year":"2022","journal-title":"J. Phys. Condens. Matter"},{"key":"10.1016\/j.psj.2026.106640_bib0024","doi-asserted-by":"crossref","DOI":"10.1063\/5.0098259","article-title":"The stability and morphology of nanobubbles on homogeneous surfaces with different wettability","volume":"34","author":"Pan","year":"2022","journal-title":"Phys. Fluids."},{"key":"10.1016\/j.psj.2026.106640_bib0025","doi-asserted-by":"crossref","first-page":"4035","DOI":"10.1016\/j.fct.2012.08.029","article-title":"Curcumin ameloriates heat stress via inhibition of oxidative stress and modulation of Nrf2\/HO-1 pathway in quail","volume":"50","author":"Sahin","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.psj.2026.106640_bib0026","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3390\/hydrogen4030031","article-title":"Hydrogen-nano-bubble-rich water in bucket\/bathtub improves intractable skin roughness","volume":"4","author":"Saitoh","year":"2023","journal-title":"Hydrogen."},{"key":"10.1016\/j.psj.2026.106640_bib0027","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.3382\/ps\/pew237","article-title":"Effects of oxygenated or hydrogenated water on growth performance, blood parameters, and antioxidant enzyme activity of broiler chickens","volume":"95","author":"Shin","year":"2016","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0028","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.advms.2021.10.002","article-title":"Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice","volume":"67","author":"Song","year":"2022","journal-title":"Adv. Med. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0029","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1017\/S0043933918000260","article-title":"Glutathione peroxidases in poultry biology: part 2. Modulation of enzymatic activities","volume":"74","author":"Surai","year":"2018","journal-title":"World Poult. Sci. J."},{"key":"10.1016\/j.psj.2026.106640_bib0030","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1186\/s42523-025-00446-4","article-title":"Linarin alleviates enterotoxigenic Escherichia coli-induced small intestinal mucosal barrier damage in a piglet model by modulating the gut microbiota","volume":"7","author":"Wang","year":"2025","journal-title":"Anim. Microbiome."},{"key":"10.1016\/j.psj.2026.106640_bib0031","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2025.1672217","article-title":"Isochlorogenic acid derived from stevia improves antioxidant capacity, immune function and intestinal microbiota in weaned piglets","volume":"12","author":"Wang","year":"2025","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0032","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/jpn.13299","article-title":"The relationship between villous height and growth performance, small intestinal mucosal enzymes activities and nutrient transporters expression in weaned piglets","volume":"104","author":"Wang","year":"2020","journal-title":"J. Anim. Physiol. Anim. Nutr."},{"key":"10.1016\/j.psj.2026.106640_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2025.104981","article-title":"Multi-omics reveal the effects and regulatory mechanism of dietary echinocystic acid supplementation on abdominal fat and liver steatosis in broiler chickens","volume":"104","author":"Xiao","year":"2025","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106640_bib0034","doi-asserted-by":"crossref","first-page":"7231","DOI":"10.1038\/s41598-022-11091-1","article-title":"Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status","volume":"12","author":"Xie","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2026.106640_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.173885","article-title":"The relevance of DHA with modulating of host-gut microbiome signatures alterations and repairing of lipids metabolism shifts","volume":"895","author":"Yu","year":"2021","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.psj.2026.106640_bib0036","doi-asserted-by":"crossref","first-page":"210","DOI":"10.3390\/fishes9060210","article-title":"The effects of different concentrations of hydrogen-rich water on the growth performance, digestive ability, antioxidant capacity, glucose metabolism pathway, mTOR signaling pathway, and gut microbiota of Largemouth Bass (Micropterus salmoides)","volume":"9","author":"Yuan","year":"2024","journal-title":"Fishes."},{"key":"10.1016\/j.psj.2026.106640_bib0037","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.jss.2018.03.024","article-title":"Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway","volume":"228","author":"Yuan","year":"2018","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.psj.2026.106640_bib0038","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/s12964-024-01540-x","article-title":"Metabolism of asparagine in the physiological state and cancer","volume":"22","author":"Yuan","year":"2024","journal-title":"Cell Commun. Signal."},{"key":"10.1016\/j.psj.2026.106640_bib0039","doi-asserted-by":"crossref","DOI":"10.1016\/j.japr.2022.100244","article-title":"Drinking with electrolyzed reduced hydrogen-rich water alters egg quality, intestinal morphology, and antioxidant activities in heat-stressed layers","volume":"31","author":"Zhang","year":"2022","journal-title":"J. Appl. Poult. Res."},{"key":"10.1016\/j.psj.2026.106640_bib0040","doi-asserted-by":"crossref","first-page":"997","DOI":"10.3390\/biology14080997","article-title":"Hydrogen-rich water attenuates diarrhea in weaned piglets via oxidative stress alleviation","volume":"14","author":"Zhang","year":"2025","journal-title":"Biology"},{"key":"10.1016\/j.psj.2026.106640_bib0041","doi-asserted-by":"crossref","first-page":"12369","DOI":"10.1021\/acs.jafc.3c04582","article-title":"Hydrogen nanobubble water: a good assistant for improving the water environment and agricultural production","volume":"71","author":"Zhao","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.psj.2026.106640_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2024.116802","article-title":"Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease","volume":"176","author":"Zheng","year":"2024","journal-title":"Biomed. Pharmacother."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126002671?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126002671?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:11:52Z","timestamp":1782601912000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579126002671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0032579126002671"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2026.106640","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oligomeric ultranano hydrogen water improves flock uniformity, antioxidant capacity and intestinal health in growth phase layer-type chickens","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2026.106640","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"106640"}}