{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:49:26Z","timestamp":1788482966609,"version":"build-2803163510"},"reference-count":57,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:00:00Z","timestamp":1773446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010814","name":"Anhui Provincial Department of Education","doi-asserted-by":"publisher","award":["2023AH040282"],"award-info":[{"award-number":["2023AH040282"]}],"id":[{"id":"10.13039\/501100010814","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31702306"],"award-info":[{"award-number":["31702306"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012554","name":"Foundation for Distinguished Young Talents in Higher Education of Henan","doi-asserted-by":"publisher","award":["DKYJ202403"],"award-info":[{"award-number":["DKYJ202403"]}],"id":[{"id":"10.13039\/501100012554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012554","name":"Foundation for Distinguished Young Talents in Higher Education of Henan","doi-asserted-by":"publisher","award":["gxyq2020038"],"award-info":[{"award-number":["gxyq2020038"]}],"id":[{"id":"10.13039\/501100012554","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007847","name":"Jilin Provincial Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007847","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012269","name":"Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003995","name":"Natural Science Foundation of Anhui Province","doi-asserted-by":"publisher","award":["1908085QC145"],"award-info":[{"award-number":["1908085QC145"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.psj.2026.106797","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T15:55:58Z","timestamp":1774367758000},"page":"106797","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Total saponins of Gynostemma pentaphyllum mitigate chronic heat stress-induced thymus and spleen inflammation in broilers via NF-\u03baB pathway activation"],"prefix":"10.1016","volume":"105","author":[{"given":"Jinxue","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjie","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feiyang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2026.106797_bib0036","article-title":"Influence of heat stress on poultry growth performance, intestinal inflammation, and immune function and potential mitigation by","volume":"12","author":"Ahmad","year":"2022","journal-title":"Probiotics, Anim. (Basel)"},{"key":"10.1016\/j.psj.2026.106797_bib0026","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s00484-023-02568-3","article-title":"Production performance, haematological parameters, serum biochemistry, and expression of HSP-70 in broiler chickens fed dietary ascorbic acid during heat stress","volume":"68","author":"Biswas","year":"2024","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.psj.2026.106797_bib0009","article-title":"Mechanistic studies of gypenosides in microglial State transition and its implications in depression-like behaviors: role of TLR4\/MyD88\/NF-\u03bab signaling","volume":"13","author":"Cao","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.psj.2026.106797_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101515","article-title":"Chitosan oligosaccharides alleviate acute heat stress-induced oxidative damage by activating ERK1\/2-mediated HO-1 and GSH-px gene expression in breast muscle of broilers","volume":"101","author":"Chang","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0015","article-title":"Chronic heat stress induces oxidative stress and induces inflammatory injury in broiler spleen via TLRs\/MyD88\/NF-\u03bab signaling pathway in broilers","volume":"11","author":"Chen","year":"2024","journal-title":"Vet. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0051","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/8061823","article-title":"Hydrogen sulfide gas exposure induces necroptosis and promotes inflammation through the MAPK\/NF- \u03ba B pathway in Broiler Spleen","volume":"2019","author":"Chi","year":"2019","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.psj.2026.106797_bib0020","article-title":"Embryonic thermal manipulation affects body performance parameters and cecum microbiome in broiler chickens in response to post-hatch chronic heat stress challenge","volume":"15","author":"Dahadha","year":"2025","journal-title":"Anim. (Basel)"},{"key":"10.1016\/j.psj.2026.106797_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2022.114411","article-title":"Resveratrol relieves chronic heat stress-induced liver oxidative damage in broilers by activating the Nrf2-Keap1 signaling pathway","volume":"249","author":"Ding","year":"2023","journal-title":"Ecotoxicol Env. Saf"},{"key":"10.1016\/j.psj.2026.106797_bib0044","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-47356-6","article-title":"Assessing different oil sources efficacy in reducing environmental heat-stress effects via improving performance, digestive enzymes, antioxidant status, and meat quality","volume":"13","author":"Elbaz","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.psj.2026.106797_bib0049","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s40104-020-00523-5","article-title":"Regulation of gene expression in chickens by heat stress","volume":"12","author":"Goel","year":"2021","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2026.106797_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.rvsc.2025.105782","article-title":"Heat stress relief for broiler chickens: dietary Rutin improved growth performance, immunity, antioxidant capacity, histopathologic picture and gene expression profile","volume":"193","author":"Hafez","year":"2025","journal-title":"Res. Vet. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0028","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1111\/jpn.13113","article-title":"Effect of dietary nutmeg oil on heat-stress tolerance-related parameters in Korean native chicken reared under hot temperature","volume":"103","author":"Hartanto","year":"2019","journal-title":"J. Anim. Physiol. Anim. Nutr. (Berl)"},{"key":"10.1016\/j.psj.2026.106797_bib0013","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3389\/fvets.2020.00046","article-title":"Heat stress causes immune abnormalities via massive damage to effect proliferation and differentiation of lymphocytes in broiler chickens","volume":"7","author":"Hirakawa","year":"2020","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2025.140133","article-title":"Chlorogenic acid mitigates heat stress-induced oxidative damage in bovine mammary epithelial cells by inhibiting NF-\u03bab-mediated NLRP3 inflammasome activation via upregulating the Nrf2 signaling pathway","volume":"301","author":"Huang","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.psj.2026.106797_bib0041","article-title":"The active constituent from Gynostemma Pentaphyllum prevents liver fibrosis through regulation of the TGF-\u03b21\/NDRG2\/MAPK axis","author":"Hui","year":"2020","journal-title":"Front. Genet."},{"key":"10.1016\/j.psj.2026.106797_bib0030","article-title":"Effects of feeding different postbiotics produced by Lactobacillus plantarum on growth performance, carcass yield, intestinal morphology","volume":"9","author":"Humam","year":"2019","journal-title":"Gut Microbiota Compos. Immune Status Growth Gene Expr. Broilers under Heat Stress, Anim. (Basel)"},{"key":"10.1016\/j.psj.2026.106797_bib0024","doi-asserted-by":"crossref","DOI":"10.36380\/jwpr.2019.6","article-title":"Effect of different bedding materials on the hematological and serum biochemical parameters of broiler chickens","author":"James","year":"2019","journal-title":"J. World s Poult. Res."},{"key":"10.1016\/j.psj.2026.106797_bib0058","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.132574","article-title":"Glycoprotein from Sargassum fusiforme exhibiting anti-inflammatory responses in vitro and in vivo via modulation of TLR4\/MyD88 and NF-\u03bab signaling","volume":"272","author":"Javed","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.psj.2026.106797_bib0007","doi-asserted-by":"crossref","DOI":"10.3390\/nu16111782","article-title":"Gynostemma pentaphyllum extract alleviates NASH in mice: exploration of inflammation and gut microbiota","volume":"16","author":"Jiang","year":"2024","journal-title":"Nutrients."},{"key":"10.1016\/j.psj.2026.106797_bib0043","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1007\/s12011-017-1094-z","article-title":"Dietary supplementation of selenium-enriched probiotics enhances meat quality of broiler chickens (Gallus gallus domesticus) raised under high ambient temperature","volume":"182","author":"Khan","year":"2018","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psj.2026.106797_bib0045","doi-asserted-by":"crossref","first-page":"9215","DOI":"10.3390\/cimb46080544","article-title":"Effects of heat-induced oxidative stress and astaxanthin on the NF-kB , NFE2L2 and PPAR\u03b1 transcription factors and cytoprotective capacity in the Thymus of broilers","volume":"46","author":"Kuehu","year":"2024","journal-title":"Curr. Issues. Mol. Biol."},{"key":"10.1016\/j.psj.2026.106797_bib0050","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1186\/s12864-016-3291-0","article-title":"Liver transcriptome response to hyperthermic stress in three distinct chicken lines","volume":"17","author":"Lan","year":"2016","journal-title":"BMC Genom."},{"key":"10.1016\/j.psj.2026.106797_bib0031","first-page":"356","article-title":"Impact of heat stress on poultry production","volume":"3","author":"Lara","year":"2013","journal-title":"Anim. (Basel)"},{"key":"10.1016\/j.psj.2026.106797_bib0056","doi-asserted-by":"crossref","first-page":"309","DOI":"10.5713\/ajas.18.0538","article-title":"Potential crosstalk of oxidative stress and immune response in poultry through phytochemicals - A review","volume":"32","author":"Lee","year":"2019","journal-title":"Asian-Australas. J. Anim. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0004","article-title":"Exploring the anti-inflammatory activity of the heat-processed gynostemma pentaphyllum extract (Actiponin \u00ae ) in RAW264.7 cells and carrageenan-induced rat models","volume":"26","author":"Lee","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2026.106489","article-title":"Dietary fucoidan supplementation ameliorates heat stress-induced liver injury in broilers via modulating peroxidation, lipid metabolism, and ferroptosis","volume":"105","author":"Liang","year":"2026","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0038","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1080\/03079457.2024.2380420","article-title":"Very virulent infectious bursal disease virus infection triggered microscopic changes, apoptosis, and inflammatory cytokines imbalance in chicken spleen and thymus","volume":"54","author":"Liu","year":"2025","journal-title":"Avian Pathol."},{"key":"10.1016\/j.psj.2026.106797_bib0022","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3382\/ps.2013-03423","article-title":"Resveratrol induces antioxidant and heat shock protein mRNA expression in response to heat stress in black-boned chickens","volume":"93","author":"Liu","year":"2014","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0019","doi-asserted-by":"crossref","first-page":"6205","DOI":"10.1016\/j.psj.2020.08.019","article-title":"Heat stress impacts on broiler performance: a systematic review and meta-analysis","volume":"99","author":"Liu","year":"2020","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0048","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101139","article-title":"Algae-derived polysaccharides supplementation ameliorates heat stress-induced impairment of bursa of Fabricius via modulating NF-\u03bab signaling pathway in broilers","volume":"100","author":"Liu","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0027","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1007\/s11250-022-03380-8","article-title":"Interactive effects of high temperature and crude protein levels on growth performance, nitrogen excretion, and fecal characteristics of broilers","volume":"54","author":"Liu","year":"2022","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.psj.2026.106797_bib0052","doi-asserted-by":"crossref","DOI":"10.3390\/md20060358","article-title":"Seaweed-derived polysaccharides attenuate heat stress-induced splenic oxidative stress and inflammatory response via regulating Nrf2 and NF-\u03bab signaling pathways","volume":"20","author":"Liu","year":"2022","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.psj.2026.106797_bib0039","article-title":"Effect of penthorum chinense pursh compound on AFB1-induced immune imbalance via JAK\/STAT signaling pathway in spleen of broiler chicken","volume":"10","author":"Lu","year":"2023","journal-title":"Vet. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2023.117350","article-title":"Viola yedoensis Makino alleviates heat stress-induced inflammation, oxidative stress, and cell apoptosis in the spleen and thymus of broilers","volume":"319","author":"Mao","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.psj.2026.106797_bib0053","doi-asserted-by":"crossref","DOI":"10.3389\/fnut.2022.821272","article-title":"Protective effects and potential mechanisms of dietary resveratrol supplementation on the spleen of broilers under heat stress","volume":"9","author":"Meng","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.psj.2026.106797_bib0018","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1631\/jzus.B1400341","article-title":"Effects of heat stress on serum insulin, adipokines, AMP-activated protein kinase, and heat shock signal molecules in dairy cows","volume":"16","author":"Min","year":"2015","journal-title":"J. Zhejiang. Univ. Sci. B"},{"key":"10.1016\/j.psj.2026.106797_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2022.103332","article-title":"Biomarkers of heat stress and mechanism of heat stress response in Avian species: current insights and future perspectives from poultry science","volume":"110","author":"Oladokun","year":"2022","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.psj.2026.106797_bib0046","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a041707","article-title":"Oxidative stress and DNA damage at telomeres","volume":"17","author":"Opresko","year":"2025","journal-title":"Cold. Spring. Harb. Perspect. Biol."},{"key":"10.1016\/j.psj.2026.106797_bib0025","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1007\/s11250-023-03842-7","article-title":"Tryptophan alleviates chronic heat stress-induced impairment of antioxidant capacities, inflammatory response, and mitochondrial function in broilers","volume":"55","author":"Ouyang","year":"2023","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.psj.2026.106797_bib0021","doi-asserted-by":"crossref","first-page":"5444","DOI":"10.2527\/jas.2014-8407","article-title":"Short-term exposure to heat stress attenuates appetite and intestinal integrity in growing pigs","volume":"92","author":"Pearce","year":"2014","journal-title":"J. Anim. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2025.178175","article-title":"Protective efficacy and mechanism of gypenosides against diabetic cataracts via the ferroptosis pathway: a study based on network pharmacology","volume":"1007","author":"Pei","year":"2025","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.psj.2026.106797_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2024.111077","article-title":"Gypenoside XLIX alleviates intestinal injury by inhibiting sepsis-induced inflammation, oxidative stress, apoptosis, and autophagy","volume":"397","author":"Ping","year":"2024","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.psj.2026.106797_bib0037","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.3382\/ps.2010-00812","article-title":"Heat stress impairs performance parameters, induces intestinal injury, and decreases macrophage activity in broiler chickens","volume":"89","author":"Quinteiro-Filho","year":"2010","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0002","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/s12917-025-04583-5","article-title":"Sodium butyrate alleviates high ambient temperature-induced oxidative stress, intestinal structural disruption, and barrier integrity for growth and production in growing layer chickens","volume":"21","author":"Sarker","year":"2025","journal-title":"BMC Vet. Res."},{"key":"10.1016\/j.psj.2026.106797_bib0057","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1749-8546-5-37","article-title":"Anti-cancer and potential chemopreventive actions of ginseng by activating Nrf2 (NFE2L2) anti-oxidative stress\/anti-inflammatory pathways","volume":"5","author":"Saw","year":"2010","journal-title":"Chin. Med."},{"key":"10.1016\/j.psj.2026.106797_bib0017","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2022.809648","article-title":"Meta-analysis and systematic review of the thermal stress response: gallus gallus domesticus show low immune responses during heat stress","volume":"13","author":"Siddiqui","year":"2022","journal-title":"Front. Physiol."},{"key":"10.1016\/j.psj.2026.106797_bib0034","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0171414","article-title":"Unique genetic responses revealed in RNA-seq of the spleen of chickens stimulated with lipopolysaccharide and short-term heat","volume":"12","author":"Van Goor","year":"2017","journal-title":"PLoS. One"},{"key":"10.1016\/j.psj.2026.106797_bib0003","article-title":"The effects of 1-deoxynojirimycin from Mulberry on oxidative stress and inflammation in laying hens and the direct effects on intestine epithelium cells In vitro","volume":"13","author":"Wang","year":"2023","journal-title":"Anim. (Basel)"},{"key":"10.1016\/j.psj.2026.106797_bib0035","article-title":"Effects of chicken hemoglobin antimicrobial peptides on intestinal mucosal immunity under chronic heat stress and vaccination responses in broilers","volume":"12","author":"Wang","year":"2025","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2023.103658","article-title":"Cold stimulation causes oxidative stress, inflammatory response and apoptosis in broiler heart via regulating Nrf2\/HO-1 and NF-\u03bab pathway","volume":"116","author":"Wei","year":"2023","journal-title":"J. Therm. Biol."},{"key":"10.1016\/j.psj.2026.106797_bib0040","article-title":"Gynostemma pentaphyllum saponins attenuate inflammation in vitro and in vivo by inhibition of NF-\u03bab and STAT3 signaling","author":"Wing-Yan","year":"2017","journal-title":"Oncotarget."},{"key":"10.1016\/j.psj.2026.106797_bib0006","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2024.118066","article-title":"Hypolipidemic effect and gut microbiota regulation of gypenoside aglycones in rats fed a high-fat diet","volume":"328","author":"Xie","year":"2024","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.psj.2026.106797_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2023.111420","article-title":"Gypenoside XLIX attenuates sepsis-induced splenic injury through inhibiting inflammation and oxidative stress","volume":"127","author":"Xu","year":"2024","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.psj.2026.106797_bib0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/01652176.2023.2228360","article-title":"The immune system of chicken and its response to H9N2 avian influenza virus","volume":"43","author":"Yang","year":"2023","journal-title":"Vet. Q."},{"key":"10.1016\/j.psj.2026.106797_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2023.115434","article-title":"Hsp90 protected chicken primary myocardial cells from heat-stress injury by inhibiting oxidative stress and calcium overload in mitochondria","volume":"209","author":"Yao","year":"2023","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.psj.2026.106797_bib0033","article-title":"Epigenomic insights into the immune regulatory mechanism of GBP4L in poultry","volume":"104","author":"Zhang","year":"2025","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.106797_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtherbio.2026.104429","article-title":"Gypenoside improves the cecal development and redox status by regulating the microbial community in heat-stressed broilers","volume":"136","author":"Zhang","year":"2026","journal-title":"J. Therm. Biol."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126004256?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126004256?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:02:53Z","timestamp":1782601373000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579126004256"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":57,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0032579126004256"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2026.106797","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Total saponins of Gynostemma pentaphyllum mitigate chronic heat stress-induced thymus and spleen inflammation in broilers via NF-\u03baB pathway activation","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2026.106797","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"106797"}}