{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T01:11:30Z","timestamp":1792545090333,"version":"4.5.0"},"reference-count":62,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010226","name":"Department of Education of Guangdong Province","doi-asserted-by":"publisher","award":["2024KTSCX198"],"award-info":[{"award-number":["2024KTSCX198"]}],"id":[{"id":"10.13039\/501100010226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010226","name":"Department of Education of Guangdong Province","doi-asserted-by":"publisher","award":["2025KCXTD021"],"award-info":[{"award-number":["2025KCXTD021"]}],"id":[{"id":"10.13039\/501100010226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007162","name":"Department of Science and Technology of Guangdong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011711","name":"Guangdong Province Department of Agriculture and Rural Affairs","doi-asserted-by":"publisher","award":["2024CXTD14"],"award-info":[{"award-number":["2024CXTD14"]}],"id":[{"id":"10.13039\/501100011711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515012201"],"award-info":[{"award-number":["2024A1515012201"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.psj.2026.107022","type":"journal-article","created":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T23:37:57Z","timestamp":1777333077000},"page":"107022","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Fucoidan alleviates spleen damage in heat-stressed broilers by suppressing oxidative stress, ferroptosis and inflammation"],"prefix":"10.1016","volume":"105","author":[{"given":"Qian-Qian","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi-Hao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan-Zi","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-Hua","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue-Qing","family":"Ye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psj.2026.107022_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102215","article-title":"Effects of brown seaweed products on growth performance, plasma biochemistry, immune response, and antioxidant capacity of broiler chickens challenged with heat stress","volume":"101","author":"Akinyemi","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0002","doi-asserted-by":"crossref","first-page":"55","DOI":"10.30539\/1y9y3h89","article-title":"Responses of poultry to heat stress and mitigation strategies during summer in tropical countries: a review","volume":"48","author":"Avi","year":"2024","journal-title":"Iraqi J. Vet. Med."},{"key":"10.1016\/j.psj.2026.107022_bib0003","doi-asserted-by":"crossref","DOI":"10.1128\/MCB.00099-20","article-title":"The molecular mechanisms regulating the KEAP1-NRF2 pathway","volume":"40","author":"Baird","year":"2020","journal-title":"Mol. Cell Biol."},{"key":"10.1016\/j.psj.2026.107022_bib0004","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.3390\/antibiotics10111285","article-title":"Heat stress-mediated activation of immune\u2013inflammatory pathways","volume":"10","author":"Cantet","year":"2021","journal-title":"Antibiotics"},{"key":"10.1016\/j.psj.2026.107022_bib0005","doi-asserted-by":"crossref","first-page":"6897","DOI":"10.3390\/ijms21186897","article-title":"Phlorotannins from fucus vesiculosus: modulation of inflammatory response by blocking NF-\u03bab signaling pathway","volume":"21","author":"Catarino","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0006","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3390\/vetsci11070293","article-title":"Chronic heat stress induces oxidative stress and induces inflammatory injury in broiler spleen via TLRs\/MyD88\/NF-\u03bab signaling pathway in broilers","volume":"11","author":"Chen","year":"2024","journal-title":"Vet. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib61","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s13045-024-01564-3","article-title":"Ferroptosis: principles and significance in health and disease","volume":"17","author":"Chen","year":"2024","journal-title":"J. Hematol. Oncol.J Hematol. Oncol."},{"key":"10.1016\/j.psj.2026.107022_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.fitote.2025.106779","article-title":"Low-molecular-weight fucoidan ameliorates ferroptosis in diabetic kidney disease through SLC7A11\/GSH\/GPX4 activation","volume":"185","author":"Chen","year":"2025","journal-title":"Fitoterapia"},{"key":"10.1016\/j.psj.2026.107022_bib0008","doi-asserted-by":"crossref","first-page":"841","DOI":"10.3390\/life15060841","article-title":"Sheng Mai San modulates the heart-gut-microbiota axis to mitigate heat stress-induced damage in rats","volume":"15","author":"Dong","year":"2025","journal-title":"Life"},{"key":"10.1016\/j.psj.2026.107022_bib0009","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.3390\/md9101731","article-title":"Therapies from Fucoidan; multifunctional marine polymers","volume":"9","author":"Fitton","year":"2011","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.psj.2026.107022_bib0010","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2025.1507152","article-title":"Climate-smart livestock nutrition in semi-arid southern african agricultural systems","volume":"12","author":"Fushai","year":"2025","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0011","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.13397","article-title":"Acute heat stress activated inflammatory signaling in porcine oxidative skeletal muscle","volume":"5","author":"Ganesan","year":"2017","journal-title":"Physiol. Rep."},{"key":"10.1016\/j.psj.2026.107022_bib0012","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1007\/s00484-019-01769-z","article-title":"Cellular antioxidant enzyme activity and biomarkers for oxidative stress are affected by heat stress","volume":"63","author":"Habashy","year":"2019","journal-title":"Int. J. Biometeorol."},{"key":"10.1016\/j.psj.2026.107022_bib0013","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1101\/gad.183434.111","article-title":"NF-\u03baB, the first quarter-century: remarkable progress and outstanding questions","volume":"26","author":"Hayden","year":"2012","journal-title":"Genes Dev."},{"key":"10.1016\/j.psj.2026.107022_bib0014","doi-asserted-by":"crossref","first-page":"6378","DOI":"10.3382\/ps\/pez471","article-title":"Dietary resveratrol supplementation inhibits heat stress-induced high-activated innate immunity and inflammatory response in spleen of yellow-feather broilers","volume":"98","author":"He","year":"2019","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0015","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ijbiomac.2020.02.315","article-title":"An insight into anti-inflammatory effects of natural polysaccharides","volume":"153","author":"Hou","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.psj.2026.107022_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2022.104976","article-title":"Effect of fucoidan on kidney injury in type 2 diabetic rats based on PI3K\/AKT\/Nrf2","volume":"90","author":"Huang","year":"2022","journal-title":"J. Funct. Foods."},{"key":"10.1016\/j.psj.2026.107022_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.103554","article-title":"Metabolomic analysis reveals biogenic selenium nanoparticles improve the meat quality of thigh muscle in heat-stressed broilers is related to the regulation of ferroptosis pathway","volume":"103","author":"Huang","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0018","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/5555796","article-title":"Regulation of laminaria polysaccharides with different degrees of sulfation during the growth of calcium oxalate crystals and their protective effects on renal epithelial cells","volume":"2021","author":"Huang","year":"2021","journal-title":"Oxid. Med. Cell Longev."},{"key":"10.1016\/j.psj.2026.107022_bib0019","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.mam.2011.10.006","article-title":"Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation","volume":"32","author":"Hybertson","year":"2011","journal-title":"Mol. Aspects. Med."},{"issue":"176","key":"10.1016\/j.psj.2026.107022_bib0020","first-page":"2765","article-title":"Oxidative stress promotes polarization of human T cell differentiation toward a T helper 2 phenotype","volume":"1950","author":"King","year":"2006","journal-title":"J. Immunol. Baltim. Md"},{"key":"10.1016\/j.psj.2026.107022_bib0021","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.carbpol.2012.03.056","article-title":"Molecular characteristics and anti-inflammatory activity of the fucoidan extracted from ecklonia cava","volume":"89","author":"Lee","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.psj.2026.107022_bib62","article-title":"System xc-\/GSH\/GPX4 axis: an important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy","volume":"13, 910292","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.psj.2026.107022_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2025.130319","article-title":"Natural products targeting the NF-\u03bab signaling pathway:potential therapeutic drug candidates","volume":"128","author":"Li","year":"2025","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.psj.2026.107022_bib0023","first-page":"1341","article-title":"Fucoidan ameliorates ferroptosis in ischemia-reperfusion-induced liver injury through Nrf2\/HO-1\/GPX4 activation","volume":"11","author":"Li","year":"2023","journal-title":"J. Clin. Transl. Hepatol."},{"key":"10.1016\/j.psj.2026.107022_bib0024","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.chemosphere.2017.09.099","article-title":"The inflammatory responses in cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in gallus gallus heart","volume":"189","author":"Li","year":"2017","journal-title":"Chemosphere"},{"key":"10.1016\/j.psj.2026.107022_bib0025","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3390\/md23080324","article-title":"Unraveling of seaweed bioactive substances and their nutritional regulation functions for poultry","volume":"23","author":"Li","year":"2025","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.psj.2026.107022_bib0026","doi-asserted-by":"crossref","first-page":"15462","DOI":"10.1007\/s11356-018-1757-0","article-title":"Alterations of antioxidant indexes and inflammatory cytokine expression aggravated hepatocellular apoptosis through mitochondrial and death receptor-dependent pathways in gallus gallus exposed to arsenic and copper","volume":"25","author":"Liu","year":"2018","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.psj.2026.107022_bib0027","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102389","article-title":"Signal amplification in the KEAP1-NRF2-ARE antioxidant response pathway","volume":"54","author":"Liu","year":"2022","journal-title":"Redox. Biol."},{"key":"10.1016\/j.psj.2026.107022_bib0028","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101139","article-title":"Algae-derived polysaccharides supplementation ameliorates heat stress-induced impairment of bursa of fabricius via modulating NF-\u03bab signaling pathway in broilers","volume":"100","author":"Liu","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0029","doi-asserted-by":"crossref","first-page":"358","DOI":"10.3390\/md20060358","article-title":"Seaweed-derived polysaccharides attenuate heat stress-induced splenic oxidative stress and inflammatory response via regulating Nrf2 and NF-\u03bab signaling pathways","volume":"20","author":"Liu","year":"2022","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.psj.2026.107022_bib0030","doi-asserted-by":"crossref","first-page":"6461","DOI":"10.3390\/ijms24076461","article-title":"Hydroxy-selenomethionine mitigated chronic heat stress-induced porcine splenic damage via activation of Nrf2\/Keap1 signal and suppression of nf\u03bab and STAT signal","volume":"24","author":"Liu","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0031","doi-asserted-by":"crossref","first-page":"5746","DOI":"10.1039\/C9NR08958F","article-title":"Nanoparticle formulated vaccines: opportunities and challenges","volume":"12","author":"Lung","year":"2020","journal-title":"Nanoscale"},{"key":"10.1016\/j.psj.2026.107022_bib0049","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.jprot.2019.01.012","article-title":"iTRAQ-based quantitative proteomics analysis of the spleen reveals innate immunity and cell death pathways associated with heat stress in broilers (Gallus gallus)","volume":"196","author":"Ma","year":"2019","journal-title":"J. Prot."},{"key":"10.1016\/j.psj.2026.107022_bib0032","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1080\/1828051X.2020.1861993","article-title":"Hepatic acute-phase response, antioxidant biomarkers and DNA fragmentation of two rabbit breeds subjected to acute heat stress","volume":"19","author":"Madkour","year":"2020","journal-title":"Ital. J. Anim. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0033","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.103790","article-title":"High-energy and high-amino acid diet enhances production performance and antioxidant capacity in yellow-feathered broilers under heat stress","volume":"103","author":"Mao","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0034","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/nri1669","article-title":"Structure and function of the spleen","volume":"5","author":"Mebius","year":"2005","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.psj.2026.107022_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2023.103141","article-title":"Heat stress and poultry production: a comprehensive review","volume":"102","author":"Oluwagbenga","year":"2023","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0036","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.3382\/ps.2010-00812","article-title":"Heat stress impairs performance parameters, induces intestinal injury, and decreases macrophage activity in broiler chickens","volume":"89","author":"Quinteiro-Filho","year":"2010","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0037","doi-asserted-by":"crossref","first-page":"7719","DOI":"10.1007\/s11356-017-1042-7","article-title":"Arsenic and\/or copper caused inflammatory response via activation of inducible nitric oxide synthase pathway and triggered heat shock protein responses in testis tissues of chicken","volume":"25","author":"Shao","year":"2018","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.psj.2026.107022_bib0038","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2020.101469","article-title":"Ferrous but not ferric iron sulfate kills photoreceptors and induces photoreceptor-dependent RPE autofluorescence","volume":"34","author":"Shu","year":"2020","journal-title":"Redox. Biol."},{"key":"10.1016\/j.psj.2026.107022_bib0039","article-title":"Chicken market will grow at a cagr of 6.00% from 2024 to 2031","author":"Mali","year":"2025","journal-title":"Cogn. Mark. Res."},{"key":"10.1016\/j.psj.2026.107022_bib0040","first-page":"404","article-title":"Heat stress, cytokines, and the immune response to exercise","volume":"19","author":"Starkie","year":"2005","journal-title":"Brain. Behav. Immun., Phys. Act., Behav., Immun. Health"},{"key":"10.1016\/j.psj.2026.107022_bib0041","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101302","article-title":"Chai hu oral liquid enhances the immune functions of both spleen and bursa of fabricius in heat-stressed broilers through strengthening TLR4-TBK1 signaling pathway","volume":"100","author":"Tang","year":"2021","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0042","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e24444","article-title":"Sulfated polysaccharides from caulerpa lentillifera: optimizing the process of extraction, structural characteristics, antioxidant capabilities, and anti-glycation properties","volume":"10","author":"Tesvichian","year":"2024","journal-title":"Heliyon."},{"key":"10.1016\/j.psj.2026.107022_bib0043","first-page":"1671","article-title":"An introduction to bioactivity of Fucoidan","volume":"14","author":"Tutuncu","year":"2019","journal-title":"Biomed. J. Sci. Tech. Res."},{"key":"10.1016\/j.psj.2026.107022_bib0044","doi-asserted-by":"crossref","first-page":"32447","DOI":"10.1021\/acsomega.0c04591","article-title":"Structure and biological activity analysis of fucoidan isolated from sargassum siliquosum","volume":"5","author":"Wang","year":"2020","journal-title":"ACS. Omega"},{"key":"10.1016\/j.psj.2026.107022_bib0045","doi-asserted-by":"crossref","first-page":"4050","DOI":"10.3390\/ijms19124050","article-title":"Fucoidan alleviates acetaminophen-induced hepatotoxicity via oxidative stress inhibition and Nrf2 translocation","volume":"19","author":"Wang","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0046","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.fsi.2020.06.031","article-title":"Zinc exerts its renal protection effect on arsenic-exposed common carp: a signaling network comprising Nrf2, NF-\u03bab and MAPK pathways","volume":"104","author":"Wang","year":"2020","journal-title":"Fish. Shellfish. Immunol."},{"key":"10.1016\/j.psj.2026.107022_bib0047","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102064","article-title":"Enteromorpha polysaccharide and yeast glycoprotein mixture improves growth, antioxidant activity, serum lipid profile and regulates lipid metabolism in broiler chickens","volume":"101","author":"Wassie","year":"2022","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0048","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2023.1151241","article-title":"Candidate genes associated with heat stress and breeding strategies to relieve its effects in dairy cattle: a deeper insight into the genetic architecture and immune response to heat stress","volume":"10","author":"Worku","year":"2023","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0050","first-page":"1553","article-title":"Research of Angelica sinensis polysaccharide\u2019s protection against bone marrow and spleen injury of rats by X-ray radiation","volume":"33","author":"Xu","year":"2017","journal-title":"Chin. Pharmacol. Bull."},{"key":"10.1016\/j.psj.2026.107022_bib0051","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.theriogenology.2023.11.027","article-title":"Heat stress induces ferroptosis of porcine sertoli cells by enhancing CYP2C9-ras- JNK axis","volume":"215","author":"Yang","year":"2024","journal-title":"Theriogenology"},{"key":"10.1016\/j.psj.2026.107022_bib0052","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.104299","article-title":"Effects of lycopene on the growth performance, meat quality, cecal metagenome, and hepatic untargeted metabolome in heat stressed broilers","volume":"103","author":"Yang","year":"2024","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0053","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.3390\/antiox12122032","article-title":"Biogenic selenium nanoparticles synthesized using alginate oligosaccharides attenuate heat stress-induced impairment of breast meat quality via regulating oxidative stress, metabolome and ferroptosis in broilers","volume":"12","author":"Yang","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.psj.2026.107022_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2025.106005","article-title":"Effects of dietary alginate oligosaccharides on meat quality, oxidative stability and metabolome of the thigh muscle in heat-stressed broilers","volume":"104","author":"Yao","year":"2025","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0055","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/s40104-025-01210-z","article-title":"The ameliorative role of phlorotannin on aflatoxin B1-induced liver oxidative stress and mitochondrial injury is related to the activation of Nrf2 and Nrf1 signaling pathways in broilers","volume":"16","author":"Ye","year":"2025","journal-title":"J. Anim. Sci. Biotechnol."},{"key":"10.1016\/j.psj.2026.107022_bib0056","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.3390\/antiox12111973","article-title":"Biogenic selenium nanoparticles synthesized with alginate oligosaccharides alleviate heat stress-induced oxidative damage to organs in broilers through activating Nrf2-mediated anti-oxidation and anti-ferroptosis pathways","volume":"12","author":"Ye","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.psj.2026.107022_bib0057","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2025.104952","article-title":"Bamboo leaf flavonoids ameliorate cyclic heat stress-induced oxidative damage in broiler liver through activation of Keap1-Nrf2 signaling pathway","volume":"104","author":"Yuan","year":"2025","journal-title":"Poult. Sci."},{"key":"10.1016\/j.psj.2026.107022_bib0058","doi-asserted-by":"crossref","first-page":"926","DOI":"10.3390\/antiox14080926","article-title":"Chronic heat stress caused lipid metabolism disorder and tissue injury in the liver of huso dauricus via oxidative-stress-mediated ferroptosis","volume":"14","author":"Zhang","year":"2025","journal-title":"Antioxidants"},{"key":"10.1016\/j.psj.2026.107022_bib0059","doi-asserted-by":"crossref","DOI":"10.1016\/j.fbio.2025.107522","article-title":"Metabolites from Lactobacillus delbrueckii subsp. Bulgaricus DLPU F-36 and l-Arginine promote immune tolerance to whey protein in rats by modulating Th1\/Th2 and Th17\/treg balance","volume":"72","author":"Zhang","year":"2025","journal-title":"Food Biosci."},{"key":"10.1016\/j.psj.2026.107022_bib0060","doi-asserted-by":"crossref","DOI":"10.1002\/fft2.70177","article-title":"Alginate oligosaccharides attenuate ochratoxin a-induced liver injury through regulating the interaction of Nrf2 and NF-\u03bab signaling pathways","author":"Zhao","year":"2026","journal-title":"Food Front. 7, e70177"}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126006516?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126006516?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T02:56:17Z","timestamp":1784688977000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579126006516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":62,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S0032579126006516"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2026.107022","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fucoidan alleviates spleen damage in heat-stressed broilers by suppressing oxidative stress, ferroptosis and inflammation","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2026.107022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"107022"}}