{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T15:33:02Z","timestamp":1793115182842,"version":"4.5.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:00:00Z","timestamp":1791158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018555","name":"Science and Technology Program of Guizhou Province","doi-asserted-by":"publisher","award":["Qiankehe Foundation-ZK [ 2026 ] General 282"],"award-info":[{"award-number":["Qiankehe Foundation-ZK [ 2026 ] General 282"]}],"id":[{"id":"10.13039\/501100018555","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018555","name":"Science and Technology Program of Guizhou Province","doi-asserted-by":"publisher","award":["QKH-ZC2022-key34"],"award-info":[{"award-number":["QKH-ZC2022-key34"]}],"id":[{"id":"10.13039\/501100018555","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Poultry Science"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.psj.2026.107910","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:50:54Z","timestamp":1791269454000},"page":"107910","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multi-omics analysis reveals gut microbiota\u2013host metabolism\u2013shell gland axis underlying eggshell deterioration in aged laying hens"],"prefix":"10.1016","volume":"105","author":[{"given":"Xudong","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinsong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingping","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8119-1798","authenticated-orcid":false,"given":"Xiongxiong","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Yue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Lei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8180-5983","authenticated-orcid":false,"given":"Fuping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.psj.2026.107910_bib0001","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.103475","article-title":"A systematic review of potential productivity, egg quality, and animal welfare implications of extended lay cycles in commercial laying hens in Canada","volume":"103","author":"Arulnathan","year":"2024","journal-title":"Poult. Sci."},{"issue":"3","key":"10.1016\/j.psj.2026.107910_bib0002","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aar3219","article-title":"Nanostructure, osteopontin, and mechanical properties of calcitic avian eggshell","volume":"4","author":"Athanasiadou","year":"2018","journal-title":"Sci. Adv."},{"issue":"3","key":"10.1016\/j.psj.2026.107910_bib0003","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1080\/00071668.2016.1161727","article-title":"Increasing persistency in lay and stabilising egg quality in longer laying cycles. What are the challenges?","volume":"57","author":"Bain","year":"2016","journal-title":"Br. Poult. Sci."},{"issue":"9","key":"10.1016\/j.psj.2026.107910_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2021.101287","article-title":"Research note: changes in eggshell quality and microstructure related to hen age during a production cycle","volume":"100","author":"Benavides-Reyes","year":"2021","journal-title":"Poult. Sci."},{"issue":"12","key":"10.1016\/j.psj.2026.107910_bib0005","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1038\/s41580-022-00506-6","article-title":"Mechanisms of mitochondrial respiratory adaptation","volume":"23","author":"Bennett","year":"2022","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"7","key":"10.1016\/j.psj.2026.107910_bib0006","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adz2892","article-title":"Elovl6 inhibits colorectal cancer progression through stearic acid-mediated mitochondrial fusion and metabolic reprogramming","volume":"12","author":"Bi","year":"2026","journal-title":"Sci. Adv."},{"key":"10.1016\/j.psj.2026.107910_bib0007","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.redox.2016.05.003","article-title":"Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration","volume":"9","author":"Carlson","year":"2016","journal-title":"Redox. Biol."},{"issue":"2","key":"10.1016\/j.psj.2026.107910_bib0008","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a035113","article-title":"Primary active Ca2+ transport systems in health and disease","volume":"12","author":"Chen","year":"2020","journal-title":"Cold. Spring. Harb. Perspect. Biol."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0009","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/s41392-023-01547-9","article-title":"Mitochondrial dynamics in health and disease: mechanisms and potential targets","volume":"8","author":"Chen","year":"2023","journal-title":"Signal. Transduct. Target. Ther."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2022.102283","article-title":"Research progress on bird eggshell quality defects: a review","volume":"102","author":"Cheng","year":"2023","journal-title":"Poult. Sci."},{"issue":"4","key":"10.1016\/j.psj.2026.107910_bib0011","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/s41579-022-00805-x","article-title":"Bile acids and the gut microbiota: metabolic interactions and impacts on disease","volume":"21","author":"Collins","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.psj.2026.107910_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.138520","article-title":"Gga-miR-34b-3p targets calbindin 1 to regulate cellular calcium ion homeostasis during eggshell calcification in chicken uterus","volume":"286","author":"Cui","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"issue":"4","key":"10.1016\/j.psj.2026.107910_bib0013","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/j.1365-2052.2011.02280.x","article-title":"Genetic variation in eggshell crystal size and orientation is large and these traits are correlated with shell thickness and are associated with eggshell matrix protein markers","volume":"43","author":"Dunn","year":"2012","journal-title":"Anim. Genet."},{"issue":"8","key":"10.1016\/j.psj.2026.107910_bib0014","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1182\/blood-2015-10-678383","article-title":"Full activation of mouse platelets requires ADP secretion regulated by SERCA3 ATPase-dependent calcium stores","volume":"128","author":"Ela\u00efb","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.psj.2026.107910_bib0015","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.theriogenology.2023.04.007","article-title":"Aging-associated increased nitric oxide production is a potential cause of inferior eggshell quality produced by aged laying hens","volume":"205","author":"Elhamouly","year":"2023","journal-title":"Theriogenology"},{"issue":"12","key":"10.1016\/j.psj.2026.107910_bib0016","doi-asserted-by":"crossref","first-page":"5664","DOI":"10.1007\/s12011-024-04121-8","article-title":"Trace minerals in laying hen diets and their effects on egg quality","volume":"202","author":"Elnesr","year":"2024","journal-title":"Biol. Trace Elem. Res."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0017","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41579-020-0433-9","article-title":"Gut microbiota in human metabolic health and disease","volume":"19","author":"Fan","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.psj.2026.107910_bib0019","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.aninu.2023.03.004","article-title":"Uterine inflammation status modulates eggshell mineralization via calcium transport and matrix protein synthesis in laying hens","volume":"13","author":"Feng","year":"2023","journal-title":"Anim. Nutr."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0018","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1186\/s12864-020-07177-7","article-title":"Uterine transcriptome analysis reveals mRNA expression changes associated with the ultrastructure differences of eggshell in young and aged laying hens","volume":"21","author":"Feng","year":"2020","journal-title":"BMC. Genomics."},{"key":"10.1016\/j.psj.2026.107910_bib0020","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.aninu.2025.11.003","article-title":"Optimizing eggshell quality in extended laying periods: insights and strategies","volume":"24","author":"Fu","year":"2026","journal-title":"Anim. Nutr."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0021","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s40104-023-00986-2","article-title":"Decreased eggshell strength caused by impairment of uterine calcium transport coincide with higher bone minerals and quality in aged laying hens","volume":"15","author":"Fu","year":"2024","journal-title":"J. Anim. Sci. Biotechnol."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0022","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12860-021-00350-0","article-title":"Avian eggshell biomineralization: an update on its structure, mineralogy and protein tool kit","volume":"22","author":"Gautron","year":"2021","journal-title":"BMC. Mol. Cell Biol."},{"key":"10.1016\/j.psj.2026.107910_bib0023","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.123308","article-title":"Emerging insights on the role of Elovl6 in human diseases: therapeutic challenges and opportunities","volume":"361","author":"Guo","year":"2025","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0024","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41580-023-00645-4","article-title":"Understanding mechanisms of antioxidant action in health and disease","volume":"25","author":"Halliwell","year":"2024","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.psj.2026.107910_bib0025","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.aninu.2025.03.024","article-title":"Disequilibrium feeding pattern more consistent with egg-laying physiology improves eggshell quality of laying hens during late laying period","volume":"23","author":"Hu","year":"2025","journal-title":"Anim. Nutr."},{"key":"10.1016\/j.psj.2026.107910_bib0027","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.theriogenology.2021.11.019","article-title":"Dietary mulberry-leaf flavonoids improve the eggshell quality of aged breeder hens","volume":"179","author":"Huang","year":"2022","journal-title":"Theriogenology"},{"issue":"8","key":"10.1016\/j.psj.2026.107910_bib0026","doi-asserted-by":"crossref","first-page":"960","DOI":"10.3390\/antiox14080960","article-title":"Puerarin enhances eggshell quality by mitigating uterine senescence in late-phase laying breeder hens","volume":"14","author":"Huang","year":"2025","journal-title":"Antioxidants"},{"issue":"5","key":"10.1016\/j.psj.2026.107910_bib0028","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/nri3430","article-title":"Role of the gut microbiota in immunity and inflammatory disease","volume":"13","author":"Kamada","year":"2013","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0029","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1186\/s12864-019-5460-4","article-title":"RNA-sequencing analysis of shell gland shows differences in gene expression profile at two time-points of eggshell formation in laying chickens","volume":"20","author":"Khan","year":"2019","journal-title":"BMC. Genomics."},{"issue":"2\u20133","key":"10.1016\/j.psj.2026.107910_bib0030","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.mam.2012.07.003","article-title":"The SLC8 gene family of sodium-calcium exchangers (NCX) - structure, function, and regulation in health and disease","volume":"34","author":"Khananshvili","year":"2013","journal-title":"Mol. Aspects. Med."},{"issue":"6","key":"10.1016\/j.psj.2026.107910_bib0031","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/nchembio.1535","article-title":"Gut microbiota-generated metabolites in animal health and disease","volume":"10","author":"Lee","year":"2014","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.psj.2026.107910_bib0032","doi-asserted-by":"crossref","DOI":"10.1016\/j.jia.2025.10.016","article-title":"Age-related functional deterioration of medullary bone is linked with senescent bone marrow microenvironment in laying hens","author":"Liao","year":"2025","journal-title":"J. Integr. Agric. In press."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0033","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/s12917-023-03719-9","article-title":"Effects of dietary Lactobacillus rhamnosus GG supplementation on the production performance, egg quality, eggshell ultrastructure, and lipid metabolism of late-phase laying hens","volume":"19","author":"Liu","year":"2023","journal-title":"BMC. Vet. Res."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0034","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/s40104-024-01074-9","article-title":"Hepatoprotective effects of magnolol in fatty liver hemorrhagic syndrome hens through shaping gut microbiota and tryptophan metabolic profile","volume":"15","author":"Lv","year":"2024","journal-title":"J. Anim. Sci. Biotechnol."},{"issue":"8","key":"10.1016\/j.psj.2026.107910_bib0035","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/s41577-024-01014-8","article-title":"Short-chain fatty acids: linking diet, the microbiome and immunity","volume":"24","author":"Mann","year":"2024","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.psj.2026.107910_bib0036","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2023.1197759","article-title":"Short chain fatty acids: the messengers from down below","volume":"17","author":"Mansuy-Aubert","year":"2023","journal-title":"Front. Neurosci."},{"issue":"6","key":"10.1016\/j.psj.2026.107910_bib0037","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1080\/00071668.2016.1209738","article-title":"Changes in egg quality traits during the last phase of production: is there potential for an extended laying cycle?","volume":"57","author":"Moln\u00e1r","year":"2016","journal-title":"Br. Poult. Sci."},{"issue":"10","key":"10.1016\/j.psj.2026.107910_bib0038","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1038\/s41579-025-01183-w","article-title":"Gut microbiota-derived short-chain fatty acids and their role in human health and disease","volume":"23","author":"Mukhopadhya","year":"2025","journal-title":"Nat. Rev. Microbiol."},{"issue":"5","key":"10.1016\/j.psj.2026.107910_bib0039","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.5851\/kosfa.2018.e41","article-title":"The influence of hen aging on eggshell ultrastructure and shell mineral components","volume":"38","author":"Park","year":"2018","journal-title":"Korean J. Food Sci. Anim. Resour."},{"issue":"5","key":"10.1016\/j.psj.2026.107910_bib0040","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1071\/AN14755","article-title":"Eggshell quality: a comparison between Fayoumi, Gimieizah and Brown Hy-Line strains for mechanical properties and ultrastructure of their eggshells","volume":"56","author":"Radwan","year":"2016","journal-title":"Anim Prod Sci"},{"issue":"2","key":"10.1016\/j.psj.2026.107910_bib0041","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2025.106314","article-title":"Ultrastructural changes in eggshell during incubation: mechanisms and implications","volume":"105","author":"Rayan","year":"2026","journal-title":"Poult. Sci."},{"issue":"3","key":"10.1016\/j.psj.2026.107910_bib0042","doi-asserted-by":"crossref","first-page":"684","DOI":"10.3390\/nu11030684","article-title":"The golden egg: nutritional value, bioactivities, and emerging benefits for Human health","volume":"11","author":"R\u00e9hault-Godbert","year":"2019","journal-title":"Nutrients."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0043","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1757-4749-2-8","article-title":"Enteropathogenic Escherichia coli, Samonella, Shigella and Yersinia: cellular aspects of host-bacteria interactions in enteric diseases","volume":"2","author":"Reis","year":"2010","journal-title":"Gut. Pathog."},{"key":"10.1016\/j.psj.2026.107910_bib0044","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.tifs.2020.10.038","article-title":"Consumer behaviour, perceptions, and preferences towards eggs: a review of the literature and discussion of industry implications","volume":"106","author":"Rondoni","year":"2020","journal-title":"Trends. Food Sci. Technol."},{"issue":"7","key":"10.1016\/j.psj.2026.107910_bib0045","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1038\/s12276-023-01028-7","article-title":"Immune regulation through tryptophan metabolism","volume":"55","author":"Seo","year":"2023","journal-title":"Exp. Mol. Med."},{"issue":"47","key":"10.1016\/j.psj.2026.107910_bib0046","doi-asserted-by":"crossref","first-page":"15853","DOI":"10.1074\/jbc.RA120.014542","article-title":"Avian eggshell formation reveals a new paradigm for vertebrate mineralization via vesicular amorphous calcium carbonate","volume":"295","author":"Stapane","year":"2020","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0047","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s40104-025-01220-x","article-title":"Dihydrosanguinarine enhances tryptophan metabolism and intestinal immune function via AhR pathway activation in broilers","volume":"16","author":"Su","year":"2025","journal-title":"J. Anim. Sci. Biotechnol."},{"issue":"22","key":"10.1016\/j.psj.2026.107910_bib0048","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.3390\/ani15223262","article-title":"Comparative study on growth performance and meat production traits of reciprocal crosses between Guizhou recessive white chickens and Qiandongnan Xiaoxiang chickens","volume":"15","author":"Tian","year":"2025","journal-title":"Animals"},{"key":"10.1016\/j.psj.2026.107910_bib0049","doi-asserted-by":"crossref","DOI":"10.1016\/j.ceca.2025.103079","article-title":"SERCA3, ubiquitous but specific calcium pumps?","volume":"132","author":"Toth","year":"2025","journal-title":"Cell Calcium"},{"issue":"2","key":"10.1016\/j.psj.2026.107910_bib0050","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1080\/00071668.2021.1955329","article-title":"Integument, mortality, and skeletal strength in extended production cycles for laying hens - effects of genotype and dietary zinc source","volume":"63","author":"Wall","year":"2022","journal-title":"Br. Poult. Sci."},{"key":"10.1016\/j.psj.2026.107910_bib0051","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.aninu.2025.06.007","article-title":"Regulatory effects of hawthorn leaf flavonoids and stevioside on the uterine function and eggshell quality in laying hens","volume":"23","author":"Wang","year":"2025","journal-title":"Anim. Nutr."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0052","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s13028-019-0449-1","article-title":"Age-related changes in the shell gland and duodenum in relation to shell quality and bone strength in commercial laying hen hybrids","volume":"61","author":"Wistedt","year":"2019","journal-title":"Acta Vet. Scand."},{"issue":"21","key":"10.1016\/j.psj.2026.107910_bib0053","first-page":"3086","article-title":"Improved eggshell quality in aged hens through circadian gut microbiota and metabolite changes induced by a 28-h","volume":"15","author":"Xu","year":"2025","journal-title":"Ahemeral Light Cycle. Animals."},{"issue":"9","key":"10.1016\/j.psj.2026.107910_bib0054","doi-asserted-by":"crossref","DOI":"10.1016\/j.psj.2024.103983","article-title":"Translucent eggs of laying hens: a review","volume":"103","author":"Xuan","year":"2024","journal-title":"Poult. Sci."},{"issue":"6","key":"10.1016\/j.psj.2026.107910_bib0055","doi-asserted-by":"crossref","DOI":"10.1111\/1541-4337.70317","article-title":"Egg freshness safety and detection techniques: a comprehensive review and future perspective","volume":"24","author":"Yang","year":"2025","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"issue":"10","key":"10.1016\/j.psj.2026.107910_bib0056","first-page":"577","article-title":"Historical influences on antibiotic resistance","volume":"15","author":"York","year":"2017","journal-title":"Nat. Rev. Microbiol."},{"issue":"1","key":"10.1016\/j.psj.2026.107910_bib0057","doi-asserted-by":"crossref","DOI":"10.1080\/19490976.2024.2437247","article-title":"Gut microbiota and microbial metabolites for osteoporosis","volume":"17","author":"Zheng","year":"2025","journal-title":"Gut. Microbes."}],"container-title":["Poultry Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126015440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0032579126015440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:39:09Z","timestamp":1793111949000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0032579126015440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":57,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S0032579126015440"],"URL":"https:\/\/doi.org\/10.1016\/j.psj.2026.107910","relation":{},"ISSN":["0032-5791"],"issn-type":[{"value":"0032-5791","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multi-omics analysis reveals gut microbiota\u2013host metabolism\u2013shell gland axis underlying eggshell deterioration in aged laying hens","name":"articletitle","label":"Article Title"},{"value":"Poultry Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psj.2026.107910","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Inc. on behalf of Poultry Science Association Inc.","name":"copyright","label":"Copyright"}],"article-number":"107910"}}