{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T08:02:27Z","timestamp":1792569747655,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100009670","name":"NARSAD","doi-asserted-by":"crossref","award":["Grant No. 24095"],"award-info":[{"award-number":["Grant No. 24095"]}],"id":[{"id":"10.13039\/100009670","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychosomatics"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.psym.2017.06.002","type":"journal-article","created":{"date-parts":[[2017,6,8]],"date-time":"2017-06-08T13:02:22Z","timestamp":1496926942000},"page":"574-580","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Feeding Systems and the Gut Microbiome: Gut-Brain Interactions With Relevance to Psychiatric Conditions"],"prefix":"10.1016","volume":"58","author":[{"given":"Brittany L.","family":"Mason","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.psym.2017.06.002_bib1","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0896-6273(02)00969-8","article-title":"The need to feed: homeostatic and hedonic control of eating","volume":"36","author":"Saper","year":"2002","journal-title":"Neuron"},{"issue":"3","key":"10.1016\/j.psym.2017.06.002_bib2","doi-asserted-by":"crossref","first-page":"629","DOI":"10.3945\/jn.108.097618","article-title":"Homeostatic and hedonic signals interact in the regulation of food intake","volume":"139","author":"Lutter","year":"2009","journal-title":"J Nutr"},{"key":"10.1016\/j.psym.2017.06.002_bib3","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0079-6123(06)53014-6","article-title":"Staying awake for dinner: hypothalamic integration of sleep, feeding, and circadian rhythms","volume":"153","author":"Saper","year":"2006","journal-title":"Prog Brain Res"},{"issue":"9","key":"10.1016\/j.psym.2017.06.002_bib4","doi-asserted-by":"crossref","first-page":"3749","DOI":"10.1210\/en.2003-0241","article-title":"Mini-review: from anorexia to obesity\u2014the yin and yang of body weight control","volume":"144","author":"Zigman","year":"2003","journal-title":"Endocrinology"},{"key":"10.1016\/j.psym.2017.06.002_bib5","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1146\/annurev-physiol-021113-170310","article-title":"The central nervous system sites mediating the orexigenic actions of ghrelin","volume":"76","author":"Mason","year":"2014","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.psym.2017.06.002_bib6","doi-asserted-by":"crossref","DOI":"10.1155\/2010\/460549","article-title":"Ghrelin\u2019s roles in stress, mood, and anxiety regulation.","volume":"2010","author":"Chuang","year":"2010","journal-title":"Int J Pept"},{"issue":"7","key":"10.1016\/j.psym.2017.06.002_bib7","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1038\/nn.2139","article-title":"The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress","volume":"11","author":"Lutter","year":"2008","journal-title":"Nat Neurosci"},{"issue":"6","key":"10.1016\/j.psym.2017.06.002_bib8","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.npep.2012.08.005","article-title":"Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut-brain axis","volume":"46","author":"Holzer","year":"2012","journal-title":"Neuropeptides"},{"issue":"1","key":"10.1016\/j.psym.2017.06.002_bib9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1055\/s-0035-1565241","article-title":"The effects of antidepressants on neuropeptide Y in patients with depression and anxiety","volume":"49","author":"Ozsoy","year":"2016","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.psym.2017.06.002_bib10","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.psyneuen.2015.11.021","article-title":"GLP-1 is both anxiogenic and antidepressant; divergent effects of acute and chronic GLP-1 on emotionality","volume":"65","author":"Anderberg","year":"2016","journal-title":"Psychoneuroendocrinology"},{"issue":"7","key":"10.1016\/j.psym.2017.06.002_bib11","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.endonu.2012.09.003","article-title":"Contributions of cortisol suppression tests to understanding of psychiatric disorders: a narrative review of literature. Endocrinologia y nutricion: organo de la Sociedad Espanola de","volume":"60","author":"Tajima-Pozo","year":"2013","journal-title":"Endocrinol Nutr"},{"key":"10.1016\/j.psym.2017.06.002_bib12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/7854_2014_304","article-title":"The interface of stress and the HPA axis in behavioural phenotypes of mental illness","volume":"18","author":"Baumeister","year":"2014","journal-title":"Curr Top Behav Neurosci"},{"key":"10.1016\/j.psym.2017.06.002_bib13","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3389\/fnins.2014.00052","article-title":"CRF and urocortin peptides as modulators of energy balance and feeding behavior during stress","volume":"8","author":"Stengel","year":"2014","journal-title":"Front Neurosci"},{"issue":"5","key":"10.1016\/j.psym.2017.06.002_bib14","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.biopsych.2012.02.016","article-title":"The role of ghrelin in reward-based eating","volume":"72","author":"Perello","year":"2012","journal-title":"Biol Psychiatry"},{"issue":"4","key":"10.1016\/j.psym.2017.06.002_bib15","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.yhbeh.2010.06.003","article-title":"Psychosocial stressor effects on cortisol and ghrelin in emotional and non-emotional eaters: influence of anger and shame","volume":"58","author":"Raspopow","year":"2010","journal-title":"Horm Behav"},{"issue":"9","key":"10.1016\/j.psym.2017.06.002_bib16","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.biopsych.2013.01.032","article-title":"Stress as a common risk factor for obesity and addiction","volume":"73","author":"Sinha","year":"2013","journal-title":"Biol Psychiatry"},{"issue":"6","key":"10.1016\/j.psym.2017.06.002_bib17","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1097\/01.psy.0000143637.63508.47","article-title":"Cortisol, hunger, and desire to binge eat following a cold stress test in obese women with binge eating disorder","volume":"66","author":"Gluck","year":"2004","journal-title":"Psychosom Med"},{"key":"10.1016\/j.psym.2017.06.002_bib18","doi-asserted-by":"crossref","first-page":"134","DOI":"10.3389\/fnins.2013.00134","article-title":"Molecular anatomy of the gut-brain axis revealed with transgenic technologies: implications in metabolic research","volume":"7","author":"Udit","year":"2013","journal-title":"Front Neurosci"},{"issue":"6","key":"10.1016\/j.psym.2017.06.002_bib19","first-page":"591","article-title":"Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options","volume":"62","author":"Konturek","year":"2011","journal-title":"J Physiol Pharmacol"},{"issue":"7402","key":"10.1016\/j.psym.2017.06.002_bib20","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nature11234","article-title":"Structure, function and diversity of the healthy human microbiome","volume":"486","author":"Consortium","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.psym.2017.06.002_bib21","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3389\/fphys.2011.00094","article-title":"Brain-gut-microbe communication in health and disease","volume":"2","author":"Grenham","year":"2011","journal-title":"Front Physiol"},{"issue":"2","key":"10.1016\/j.psym.2017.06.002_bib22","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/cmi.2010.67","article-title":"The role of gut microbiota (commensal bacteria) and the mucosal barrier in the pathogenesis of inflammatory and autoimmune diseases and cancer: contribution of germ-free and gnotobiotic animal models of human diseases","volume":"8","author":"Tlaskalova-Hogenova","year":"2011","journal-title":"Cell Mol Immunol"},{"issue":"7461","key":"10.1016\/j.psym.2017.06.002_bib23","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/nature12331","article-title":"Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota","volume":"500","author":"Atarashi","year":"2013","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.psym.2017.06.002_bib24","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.chom.2015.12.016","article-title":"Taking it personally: personalized utilization of the human microbiome in health and disease","volume":"19","author":"Zmora","year":"2016","journal-title":"Cell Host Microbe"},{"issue":"4","key":"10.1016\/j.psym.2017.06.002_bib25","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1124\/mol.112.083550","article-title":"Sex-biased stress signaling: the corticotropin-releasing factor receptor as a model","volume":"83","author":"Valentino","year":"2013","journal-title":"Mol Pharmacol"},{"issue":"6123","key":"10.1016\/j.psym.2017.06.002_bib26","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1126\/science.1233521","article-title":"Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity","volume":"339","author":"Markle","year":"2013","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.psym.2017.06.002_bib27","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1136\/gut.48.5.630","article-title":"Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat","volume":"48","author":"Santos","year":"2001","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.psym.2017.06.002_bib28","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1023\/A:1013204612762","article-title":"Physical and psychological stress in rats enhances colonic epithelial permeability via peripheral CRH","volume":"47","author":"Saunders","year":"2002","journal-title":"Dig Dis Sci"},{"issue":"8","key":"10.1016\/j.psym.2017.06.002_bib29","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/j.1365-2982.2012.01928.x","article-title":"Acute experimental stress evokes a differential gender-determined increase in human intestinal macromolecular permeability","volume":"24","author":"Alonso","year":"2012","journal-title":"Neurogastroenterol Motil"},{"issue":"2","key":"10.1016\/j.psym.2017.06.002_bib30","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/1574-6941.12228","article-title":"A gut microbiota-targeted dietary intervention for amelioration of chronic inflammation underlying metabolic syndrome","volume":"87","author":"Xiao","year":"2014","journal-title":"FEMS Microbiol Ecol"},{"issue":"12","key":"10.1016\/j.psym.2017.06.002_bib31","doi-asserted-by":"crossref","first-page":"R1065","DOI":"10.1152\/ajpregu.00551.2012","article-title":"More than just a gut instinct-the potential interplay between a baby\u2019s nutrition, its gut microbiome, and the epigenome","volume":"304","author":"Mischke","year":"2013","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.psym.2017.06.002_bib32","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.neuint.2016.06.011","article-title":"The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?","volume":"99","author":"Stilling","year":"2016","journal-title":"Neurochem Int"},{"issue":"3","key":"10.1016\/j.psym.2017.06.002_bib33","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1128\/iai.9.3.591-598.1974","article-title":"Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract","volume":"9","author":"Tannock","year":"1974","journal-title":"Infect Immun"},{"issue":"6","key":"10.1016\/j.psym.2017.06.002_bib34","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1038\/mp.2012.77","article-title":"The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner","volume":"18","author":"Clarke","year":"2013","journal-title":"Mol Psychiatry"},{"issue":"9","key":"10.1016\/j.psym.2017.06.002_bib35","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1038\/ijo.2015.84","article-title":"The role of short chain fatty acids in appetite regulation and energy homeostasis","volume":"39","author":"Byrne","year":"2015","journal-title":"Int J Obes"},{"issue":"2","key":"10.1016\/j.psym.2017.06.002_bib36","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1053\/j.gastro.2011.04.052","article-title":"The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice","volume":"141","author":"Bercik","year":"2011","journal-title":"Gastroenterology"},{"issue":"6150","key":"10.1016\/j.psym.2017.06.002_bib37","doi-asserted-by":"crossref","first-page":"1241214","DOI":"10.1126\/science.1241214","article-title":"Gut microbiota from twins discordant for obesity modulate metabolism in mice","volume":"341","author":"Ridaura","year":"2013","journal-title":"Science"},{"issue":"Pt 1","key":"10.1016\/j.psym.2017.06.002_bib38","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1113\/jphysiol.2004.063388","article-title":"Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice","volume":"558","author":"Sudo","year":"2004","journal-title":"J Physiol"},{"issue":"9","key":"10.1016\/j.psym.2017.06.002_bib39","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.psyneuen.2012.03.007","article-title":"Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology","volume":"37","author":"Dinan","year":"2012","journal-title":"Psychoneuroendocrinology"},{"issue":"4","key":"10.1016\/j.psym.2017.06.002_bib40","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.neuroscience.2010.08.005","article-title":"Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression","volume":"170","author":"Desbonnet","year":"2010","journal-title":"Neuroscience"},{"issue":"11","key":"10.1016\/j.psym.2017.06.002_bib41","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1016\/j.psyneuen.2012.03.024","article-title":"Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats","volume":"37","author":"Ait-Belgnaoui","year":"2012","journal-title":"Psychoneuroendocrinology"},{"issue":"2","key":"10.1016\/j.psym.2017.06.002_bib42","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.jpsychires.2008.03.009","article-title":"The probiotic Bifidobacteria infantis: an assessment of potential antidepressant properties in the rat","volume":"43","author":"Desbonnet","year":"2008","journal-title":"J Psychiatr Res"},{"issue":"9","key":"10.1016\/j.psym.2017.06.002_bib43","doi-asserted-by":"crossref","first-page":"e7125","DOI":"10.1371\/journal.pone.0007125","article-title":"Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients","volume":"4","author":"Armougom","year":"2009","journal-title":"PLoS ONE"},{"issue":"9","key":"10.1016\/j.psym.2017.06.002_bib44","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1097\/PSY.0000000000000247","article-title":"The intestinal microbiota in acute anorexia nervosa and during renourishment: relationship to depression, anxiety, and eating disorder psychopathology","volume":"77","author":"Kleiman","year":"2015","journal-title":"Psychosom Med"},{"key":"10.1016\/j.psym.2017.06.002_bib45","doi-asserted-by":"crossref","first-page":"e458","DOI":"10.1038\/tp.2014.98","article-title":"Bacterial ClpB heat-shock protein, an antigen-mimetic of the anorexigenic peptide [alpha]-MSH, at the origin of eating disorders","volume":"4","author":"Tennoune","year":"2014","journal-title":"Transl Psychiatry"},{"issue":"7","key":"10.1016\/j.psym.2017.06.002_bib46","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1073\/pnas.1010529108","article-title":"Normal gut microbiota modulates brain development and behavior","volume":"108","author":"Diaz Heijtz","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"5","key":"10.1016\/j.psym.2017.06.002_bib47","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1017\/S0007114510004319","article-title":"Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects","volume":"105","author":"Messaoudi","year":"2011","journal-title":"Br J Nutr"},{"issue":"1","key":"10.1016\/j.psym.2017.06.002_bib48","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nm1521","article-title":"Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors","volume":"13","author":"Rousseaux","year":"2007","journal-title":"Nat Med"},{"issue":"38","key":"10.1016\/j.psym.2017.06.002_bib49","doi-asserted-by":"crossref","first-page":"16050","DOI":"10.1073\/pnas.1102999108","article-title":"Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve","volume":"108","author":"Bravo","year":"2011","journal-title":"Proc Ntl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.psym.2017.06.002_bib50","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jad.2012.02.023","article-title":"Increased IgA and IgM responses against gut commensals in chronic depression: further evidence for increased bacterial translocation or leaky gut","volume":"141","author":"Maes","year":"2012","journal-title":"J Affect Disord"},{"key":"10.1016\/j.psym.2017.06.002_bib51","doi-asserted-by":"crossref","first-page":"e939","DOI":"10.1038\/tp.2016.191","article-title":"Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognition in healthy volunteers","volume":"6","author":"Allen","year":"2016","journal-title":"Transl Psychiatry"},{"issue":"9","key":"10.1016\/j.psym.2017.06.002_bib52","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1016\/j.nutres.2016.06.009","article-title":"Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials","volume":"36","author":"Pirbaglou","year":"2016","journal-title":"Nutr Res"}],"container-title":["Psychosomatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0033318217301482?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0033318217301482?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T08:12:22Z","timestamp":1635495142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0033318217301482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":52,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S0033318217301482"],"URL":"https:\/\/doi.org\/10.1016\/j.psym.2017.06.002","relation":{},"ISSN":["0033-3182"],"issn-type":[{"value":"0033-3182","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Feeding Systems and the Gut Microbiome: Gut-Brain Interactions With Relevance to Psychiatric Conditions","name":"articletitle","label":"Article Title"},{"value":"Psychosomatics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psym.2017.06.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Academy of Psychosomatic Medicine. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}