{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T13:33:03Z","timestamp":1790947983385,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychosomatics"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.psym.2018.11.002","type":"journal-article","created":{"date-parts":[[2018,11,13]],"date-time":"2018-11-13T12:01:45Z","timestamp":1542110505000},"page":"129-138","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical and Toxicological Profile of NBOMes: A Systematic Review"],"prefix":"10.1016","volume":"60","author":[{"given":"Nino Cesar","family":"Marchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Nichterwitz","family":"Scherer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Let\u00edcia Schwanck","family":"Fara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lysa","family":"Remy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafaela","family":"Ornel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique","family":"Reis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Zamboni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Paim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ta\u00eds Regina","family":"Fiorentin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos Alberto Yasin","family":"Wayhs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisia","family":"Von Diemen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Pechansky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix Henrique Paim","family":"Kessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata Pereira","family":"Limberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psym.2018.11.002_bib0001","doi-asserted-by":"crossref","DOI":"10.1111\/add.12287","article-title":"Getting up to speed with the public health and regulatory challenges posed by new psychoactive substances in the information age","author":"Griffiths","year":"2013","journal-title":"Addiction"},{"key":"10.1016\/j.psym.2018.11.002_bib0003","doi-asserted-by":"crossref","DOI":"10.1002\/dta.1397","article-title":"Analytical characterization of three hallucinogenic N-(2-methoxy)benzyl derivatives of the 2C-series of phenethylamine drugs","author":"Zuba","year":"2013","journal-title":"Drug Test Anal"},{"key":"10.1016\/j.psym.2018.11.002_bib0004","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1177\/0269881114523866","article-title":"The NBOMe hallucinogenic drug series: patterns of use, characteristics of users and self-reported effects in a large international sample","volume":"28","author":"Lawn","year":"2014","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.psym.2018.11.002_bib0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2012.08.027","article-title":"25C-NBOMe\u2014new potent hallucinogenic substance identified on the drug market","author":"Zuba","year":"2013","journal-title":"Forensic Sci Int"},{"key":"10.1016\/j.psym.2018.11.002_bib0006","doi-asserted-by":"crossref","DOI":"10.1021\/cn400216u","article-title":"Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A\/2Cagonists","author":"Hansen","year":"2014","journal-title":"ACS Chem Neurosci"},{"key":"10.1016\/j.psym.2018.11.002_bib0007","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2013.10.015","article-title":"Postmortem detection of 25I-NBOMe [2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine] in fluids and tissues determined by high performance liquid chromatography with tandem mass spectrometry from a traumatic death","author":"Poklis","year":"2014","journal-title":"Forensic Sci Int"},{"key":"10.1016\/j.psym.2018.11.002_bib0008","doi-asserted-by":"crossref","DOI":"10.1016\/j.psym.2014.11.002","article-title":"Toxicities associated with NBOMe ingestion-a novel class of potent hallucinogens: a review of the literature","author":"Suzuki","year":"2015","journal-title":"Psychosomatics"},{"key":"10.1016\/j.psym.2018.11.002_bib0010","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3109\/15563650.2013.802795","article-title":"Severe clinical toxicity associated with analytically confirmed recreational use of 25I-NBOMe: case series","volume":"51","author":"Hill","year":"2013","journal-title":"Clin Toxicol (Phila)"},{"key":"10.1016\/j.psym.2018.11.002_bib0011","doi-asserted-by":"crossref","DOI":"10.3109\/15563650.2013.772191","article-title":"A case of 251-NBOMe (25-1) intoxication: a new potent 5-HT2A agonist designer drug","author":"Rose","year":"2013","journal-title":"Clin Toxicol"},{"key":"10.1016\/j.psym.2018.11.002_bib0012","doi-asserted-by":"crossref","DOI":"10.1007\/s13181-013-0314-y","article-title":"2-(4-Iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine (25I-NBOMe): clinical case with unique confirmatory testing","author":"Stellpflug","year":"2014","journal-title":"J Med Toxicol"},{"key":"10.1016\/j.psym.2018.11.002_bib0014","doi-asserted-by":"crossref","DOI":"10.1590\/1516-4446-2015-1774","article-title":"NBOMe: a new dangerous drug similar to LSD","author":"Remy","year":"2015","journal-title":"Rev Bras Psiquiatr"},{"key":"10.1016\/j.psym.2018.11.002_bib0015","doi-asserted-by":"crossref","DOI":"10.1080\/02791072.2014.960111","article-title":"\u201cMy friend said it was good LSD\u201d: a suicide attempt following analytically confirmed 25I-NBOMe ingestion","author":"Suzuki","year":"2014","journal-title":"J Psychoactive Drugs"},{"key":"10.1016\/j.psym.2018.11.002_bib0016","doi-asserted-by":"crossref","DOI":"10.1002\/dta.2171","article-title":"Characterization of hallucinogenic phenethylamines using high-resolution mass spectrometry for non-targeted screening purposes","author":"Pasin","year":"2017","journal-title":"Drug Test Anal"},{"key":"10.1016\/j.psym.2018.11.002_bib0017","doi-asserted-by":"crossref","DOI":"10.1016\/j.jchromb.2016.12.018","article-title":"Identification of novel psychoactive substances 25B-NBOMe and 4-CMC in biological material using HPLC-Q-TOF-MS and their quantification in blood using UPLC\u2013MS\/MS in case of severe intoxications","author":"Wiergowski","year":"2017","journal-title":"J Chromatogr B Anal Technol Biomed Life Sci"},{"key":"10.1016\/j.psym.2018.11.002_bib0018","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/dta.1815","article-title":"Simple and rapid screening procedure for 143 new psychoactive substances by liquid chromatography-tandem mass spectrometry","volume":"8","author":"Adamowicz","year":"2016","journal-title":"Drug Test Anal"},{"key":"10.1016\/j.psym.2018.11.002_bib0019","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/jat\/bku085","article-title":"An evaluation of 25B-, 25C-, 25D-, 25H-, 25I- and 25T2-NBOMe via LC-MS-MS: method validation and analyte stability","volume":"38","author":"Johnson","year":"2014","journal-title":"J Anal Toxicol"},{"key":"10.1016\/j.psym.2018.11.002_bib0020","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.ijsu.2010.02.007","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"8","author":"Moher","year":"2010","journal-title":"Int J Surg"},{"key":"10.1016\/j.psym.2018.11.002_bib0021","doi-asserted-by":"crossref","DOI":"10.1016\/j.tips.2008.06.006","article-title":"Serotonin research: contributions to understanding psychoses","author":"Geyer","year":"2008","journal-title":"Trends Pharmacol Sci"},{"issue":"3","key":"10.1016\/j.psym.2018.11.002_bib0022","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0022-3565(25)20792-3","article-title":"LSD and the phenethylamine hallucinogen DOI are potent partial agonists at 5-HT2A receptors on interneurons in rat piriform cortex","volume":"278","author":"Marek","year":"1996","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.psym.2018.11.002_bib0023","doi-asserted-by":"crossref","DOI":"10.1097\/PAF.0000000000000082","article-title":"Pathological findings in 2 cases of fatal 25I-NBOMe toxicity","author":"Walterscheid","year":"2014","journal-title":"Am J Forensic Med Pathol"},{"key":"10.1016\/j.psym.2018.11.002_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajem.2015.04.065","article-title":"Severe poisoning after self-reported use of 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine, a novel substituted amphetamine: a case series","volume":"33","author":"Hieger","year":"2015","journal-title":"Am J Emerg Med"},{"issue":"3","key":"10.1016\/j.psym.2018.11.002_bib0025","article-title":"Intoxications associated with agitation, tachycardia, hypertension, and Fever: differential diagnosis, evaluation, and management","volume":"15","author":"Keary","year":"2013","journal-title":"Prim Care Companion CNS Disord"},{"key":"10.1016\/j.psym.2018.11.002_bib0026","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1080\/10550887.2014.950027","article-title":"NBOMe designer drug exposures reported to Texas poison centers","volume":"33","author":"Forrester","year":"2014","journal-title":"J Addict Dis"},{"key":"10.1016\/j.psym.2018.11.002_bib0027","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/734749","article-title":"25C-NBOMe: preliminary data on pharmacology, psychoactive effects, and toxicity of a new potent and dangerous hallucinogenic drug","volume":"2014","author":"Bersani","year":"2014","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.psym.2018.11.002_bib0028","doi-asserted-by":"crossref","DOI":"10.1093\/jat\/bkv058","article-title":"Fatal intoxications with 25B-NBOMe and 25I-NBOMe in Indiana during 2014","author":"Shanks","year":"2015","journal-title":"J Anal Toxicol"}],"container-title":["Psychosomatics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0033318218304882?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0033318218304882?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T01:41:42Z","timestamp":1775266902000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0033318218304882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S0033318218304882"],"URL":"https:\/\/doi.org\/10.1016\/j.psym.2018.11.002","relation":{},"ISSN":["0033-3182"],"issn-type":[{"value":"0033-3182","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical and Toxicological Profile of NBOMes: A Systematic Review","name":"articletitle","label":"Article Title"},{"value":"Psychosomatics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psym.2018.11.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Academy of Consultation-Liaison Psychiatry. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}