{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T17:13:37Z","timestamp":1773422017258,"version":"3.50.1"},"reference-count":53,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,11,1]],"date-time":"2011-11-01T00:00:00Z","timestamp":1320105600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychoneuroendocrinology"],"published-print":{"date-parts":[[2011,11]]},"DOI":"10.1016\/j.psyneuen.2011.03.020","type":"journal-article","created":{"date-parts":[[2011,5,1]],"date-time":"2011-05-01T15:35:29Z","timestamp":1304264129000},"page":"1460-1469","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Glucocorticoid and mineralocorticoid receptor polymorphisms and clinical characteristics in bipolar disorder patients"],"prefix":"10.1016","volume":"36","author":[{"given":"A.T.","family":"Spijker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.J.","family":"Giltay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.F.C.","family":"van Rossum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Manenschijn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.H.","family":"DeRijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Haffmans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.G.","family":"Zitman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Hoencamp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.psyneuen.2011.03.020_bib0005","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1002\/ajmg.b.30886","article-title":"Glucocorticoid receptor gene polymorphisms and childhood adversity are associated with depression: new evidence for a gene-environment interaction","volume":"150B","author":"Bet","year":"2009","journal-title":"Am. J. Med. Genet. B: Neuropsychiatr. Genet."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0010","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1046\/j.1365-2265.2001.01383.x","article-title":"Seasonal variation in glucocorticoid receptor binding characteristics in human mononuclear leucocytes","volume":"55","author":"Blackhurst","year":"2001","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0015","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1365-2826.2010.01955.x","article-title":"Circadian timekeeping and multiple timescale neuroendocrine rhythms","volume":"22","author":"Bonnefont","year":"2010","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0020","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s10519-010-9385-6","article-title":"No associations between single nucleotide polymorphisms in corticoid receptor genes and heart rate and cortisol responses to a standardized social stress test in adolescents: the TRAILS study","volume":"41","author":"Bouma","year":"2011","journal-title":"Behav. Genet."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0025","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0006-3223(97)00274-6","article-title":"Plasma dexamethasone concentration and cortisol response during manic episodes","volume":"43","author":"Cassidy","year":"1998","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0030","first-page":"411","article-title":"Circadian secretion of cortisol in bipolar disorder","volume":"26","author":"Cervantes","year":"2001","journal-title":"J. Psychiatry Neurosci."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0035","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nrn1683","article-title":"Stress and the brain: from adaptation to disease","volume":"6","author":"De Kloet","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0040","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/ncpendmet0403","article-title":"Therapy insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression?","volume":"3","author":"De Kloet","year":"2007","journal-title":"Nat. Clin. Pract. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0050","doi-asserted-by":"crossref","first-page":"5083","DOI":"10.1210\/jc.2006-0915","article-title":"A common polymorphism in the mineralocorticoid receptor modulates stress responsiveness","volume":"12","author":"DeRijk","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0055","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.ejphar.2008.03.012","article-title":"Corticosteroid receptor\u2013gene variants: modulators of the stress\u2013response and implications for mental health","volume":"585","author":"DeRijk","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0060","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.ejphar.2007.11.072","article-title":"Corticosteroid receptor polymorphisms: determinants of vulnerability and resilience","volume":"583","author":"DeRijk","year":"2008","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0065","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1159\/000216192","article-title":"Single nucleotide polymorphisms related to HPA axis reactivity","volume":"16","author":"DeRijk","year":"2009","journal-title":"Neuroimmunomodulation"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0070","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000321235","article-title":"Mineralocorticoid receptor gene variants as determinants of HPA axis regulation and behavior","volume":"20","author":"DeRijk","year":"2011","journal-title":"Endocr. Dev."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0075","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1399-5618.2006.00338.x","article-title":"Salivary cortisol secretion in remitted bipolar patients and offspring of bipolar parents","volume":"8","author":"Deshauer","year":"2006","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0080","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1399-5618.2009.00770.x","article-title":"High cortisol levels in the offspring of parents with bipolar disorder during two weeks of daily sampling","volume":"12","author":"Ellenbogen","year":"2010","journal-title":"Bipolar Disord."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0085","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1176\/ajp.147.9.1194","article-title":"Life events and the course of bipolar disorder","volume":"147","author":"Ellicott","year":"1990","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0090","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1017\/S0033291707000864","article-title":"Clinical and prognostic implications of seasonal pattern in bipolar disorder: a 10-year follow-up of 302 patients","volume":"37","author":"Goikolea","year":"2007","journal-title":"Psychol. Med."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0095","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1176\/appi.ajp.2008.08010098","article-title":"Sleep and circadian rhythms in bipolar disorder: seeking synchrony, harmony, and regulation","volume":"165","author":"Harvey","year":"2008","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0100","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0165-0327(00)00352-9","article-title":"Stress, hypercortisolism and corticosteroid receptors in depression: implications for therapy","volume":"62","author":"Holsboer","year":"2001","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0105","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/j.1365-2826.2005.01326.x","article-title":"Measuring seasonal time within the circadian system: regulation of the suprachiasmatic nuclei by photoperiod","volume":"17","author":"Johnston","year":"2005","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0110","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1038\/sj.npp.1301260","article-title":"Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors","volume":"32","author":"Kuningas","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1601-5215.2008.00342.x","article-title":"Association of glucocorticoid receptor polymorphisms with the susceptibility to major depressive disorder and treatment responses in Korean depressive patients","volume":"21","author":"Lee","year":"2009","journal-title":"Acta Neuropsychiatrica"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0120","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0165-0327(01)00430-X","article-title":"The Stanley Foundation Bipolar Treatment Outcome Network I. Longitudinal methodology","volume":"67","author":"Leverich","year":"2001","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0125","doi-asserted-by":"crossref","first-page":"506","DOI":"10.4088\/JCP.v64n0503","article-title":"Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network","volume":"64","author":"Leverich","year":"2003","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0130","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0165-0327(97)01441-9","article-title":"Seasonal variation in postdexamethasone cortisol values in depressed inpatients: results of least squares cosine spectral analysis","volume":"44","author":"Maes","year":"1997","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0135","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/00048670802607220","article-title":"Characteristics of bipolar disorder in an Australian specialist outpatient clinic: comparison across large datasets","volume":"43","author":"Mitchell","year":"2009","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0140","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1176\/appi.ajp.161.8.1447","article-title":"Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar Network","volume":"161","author":"Nolen","year":"2004","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0145","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.psyneuen.2009.08.016","article-title":"Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award winner","volume":"34","author":"Otte","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0150","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1038\/sj.bjp.0704368","article-title":"Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters","volume":"134","author":"Pariante","year":"2001","journal-title":"Brit. J. Pharmacol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0155","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.biopsych.2004.01.022","article-title":"Long-term implications of early onset in bipolar disorder: data from the first 1000 participants in the systematic treatment enhancement program for bipolar disorder (STEP-BD)","volume":"55","author":"Perlis","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0160","doi-asserted-by":"crossref","first-page":"3402","DOI":"10.1210\/en.2006-1432","article-title":"Short days increase hypothalamic\u2013pituitary\u2013adrenal axis responsiveness","volume":"148","author":"Pyter","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0165","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1210\/me.2004-0467","article-title":"Increased expression of the glucocorticoid receptor-A translational isoform as a result of the ER22\/23EK polymorphism","volume":"19","author":"Russcher","year":"2005","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0170","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.4088\/JCP.09r05259gre","article-title":"The neurobiology of the switch process in bipolar disorder: a review","volume":"71","author":"Salvadore","year":"2010","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0175","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/0006-3223(95)00064-X","article-title":"Combined dexamethasone\/corticotropin-releasing hormone test in acute and remitted manic patients, in acute depression, and in normal controls: I","volume":"38","author":"Schmider","year":"1995","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0180","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1111\/j.1749-6632.2009.04985.x","article-title":"Glucocorticoid receptor polymorphisms in major depression. Focus on glucocorticoid sensitivity and neurocognitive functioning","volume":"1179","author":"Spijker","year":"2009","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0185","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1210\/jc.2003-031235","article-title":"Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype","volume":"89","author":"Stevens","year":"2004","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0190","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0165-0327(01)00432-3","article-title":"The Stanley Foundation Bipolar Treatment Outcome Network II. Demographics and illness characteristics of the first 261 patients","volume":"67","author":"Suppes","year":"2001","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0195","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1111\/j.1460-9568.2007.05421.x","article-title":"Seasonal variations of clock gene expression in the suprachiasmatic nuclei and pars tuberalis of the European hamster (Cricetus cricetus)","volume":"25","author":"Tournier","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0200","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1093\/bioinformatics\/btm058","article-title":"A new JAVA interface implementation of THESIAS: testing haplotype effects in association studies","volume":"23","author":"Tregouet","year":"2007","journal-title":"Bioinformatics"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0205","doi-asserted-by":"crossref","first-page":"2800","DOI":"10.1210\/jc.2005-2119","article-title":"Glucocorticoid receptor polymorphism affects transrepression but not transactivation","volume":"91","author":"Van den Akker","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0210","article-title":"Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: implication for the stress response","author":"Van Leeuwen","year":"2010","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0215","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.psyneuen.2009.07.006","article-title":"Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone","volume":"35","author":"Van Leeuwen","year":"2010","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0220","doi-asserted-by":"crossref","first-page":"3128","DOI":"10.2337\/diabetes.51.10.3128","article-title":"A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels","volume":"51","author":"Van Rossum","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0225","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1046\/j.1365-2265.2003.01888.x","article-title":"Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index","volume":"59","author":"Van Rossum","year":"2003","journal-title":"Clin. Endocrinol."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0230","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1210\/rp.59.1.333","article-title":"Polymorphisms in the glucocorticoid receptor gene and their associations with metabolic parameters and body composition","volume":"59","author":"van Rossum","year":"2004","journal-title":"Recent Prog. Horm. Res."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0235","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.biopsych.2006.02.007","article-title":"Polymorphisms of the glucocorticoid receptor gene and major depression","volume":"59","author":"Van Rossum","year":"2006","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0240","first-page":"393","article-title":"The MINI-International neuropsychiatric interview. A brief structured diagnostic psychiatric interview for DSM-IV en ICD-10 psychiatric disorders","volume":"49","author":"Van Vliet","year":"2007","journal-title":"Tijdschrift voor Psychiatrie"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0245","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1038\/sj.npp.1300898","article-title":"Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression","volume":"31","author":"Van West","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0250","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1210\/jc.2008-2194","article-title":"A glucocorticoid receptor gene haplotype (TthIII1\/ER22\/23EK\/9beta) is associated with a more aggressive disease course in multiple sclerosis","volume":"94","author":"Van Winsen","year":"2009","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0255","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/j.psyneuen.2009.04.024","article-title":"Associations between sociodemographic, sampling and health factors and various salivary cortisol indicators in a large sample without psychopathology","volume":"34","author":"Vreeburg","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0260","first-page":"4015","article-title":"Seasonal variation in glucocorticoid activity in healthy men","volume":"82","author":"Walker","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0265","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1038\/sj.npp.1300471","article-title":"Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder","volume":"29","author":"Young","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2011.03.020_bib0270","doi-asserted-by":"crossref","first-page":"4493","DOI":"10.1523\/JNEUROSCI.4530-04.2005","article-title":"The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers","volume":"25","author":"Zhou","year":"2005","journal-title":"J. Neurosci."}],"container-title":["Psychoneuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453011001090?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453011001090?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:38:03Z","timestamp":1759682283000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306453011001090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,11]]},"references-count":53,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2011,11]]}},"alternative-id":["S0306453011001090"],"URL":"https:\/\/doi.org\/10.1016\/j.psyneuen.2011.03.020","relation":{},"ISSN":["0306-4530"],"issn-type":[{"value":"0306-4530","type":"print"}],"subject":[],"published":{"date-parts":[[2011,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Glucocorticoid and mineralocorticoid receptor polymorphisms and clinical characteristics in bipolar disorder patients","name":"articletitle","label":"Article Title"},{"value":"Psychoneuroendocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psyneuen.2011.03.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}