{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T06:33:51Z","timestamp":1792737231005,"version":"4.5.0"},"reference-count":195,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychoneuroendocrinology"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1016\/j.psyneuen.2011.05.014","type":"journal-article","created":{"date-parts":[[2011,7,8]],"date-time":"2011-07-08T21:01:44Z","timestamp":1310158904000},"page":"1-19","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":100,"title":["Stress and animal models of inflammatory bowel disease\u2014An update on the role of the hypothalamo\u2013pituitary\u2013adrenal axis"],"prefix":"10.1016","volume":"37","author":[{"given":"S.O.","family":"Reber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psyneuen.2011.05.014_bib0005","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/sj.mp.4000473","article-title":"Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia","volume":"4","author":"Agid","year":"1999","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0010","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.psyneuen.2009.03.017","article-title":"Gene\u2013environment interactions predict cortisol responses after acute stress: implications for the etiology of depression","volume":"34","author":"Alexander","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0015","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/nn1399","article-title":"Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus","volume":"8","author":"Amat","year":"2005","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0020","doi-asserted-by":"crossref","first-page":"R2164","DOI":"10.1152\/ajpregu.2000.279.6.R2164","article-title":"Bacterial translocation can increase plasma corticosterone and brain catecholamine and indoleamine metabolism","volume":"279","author":"Ando","year":"2000","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0025","first-page":"29","article-title":"Etiology and pathophysiology of inflammatory bowel disease-environmental factors","volume":"47","author":"Andus","year":"2000","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0030","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1189\/jlb.0303090","article-title":"Expression of glucocorticoid resistance following social stress requires a second signal","volume":"74","author":"Avitsur","year":"2003","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0035","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0165-5728(02)00010-3","article-title":"Social disruption-induced glucocorticoid resistance: kinetics and site specificity","volume":"124","author":"Avitsur","year":"2002","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0040","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1006\/hbeh.2001.1653","article-title":"Social stress induces glucocorticoid resistance in subordinate animals","volume":"39","author":"Avitsur","year":"2001","journal-title":"Horm. Behav."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0045","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.bbi.2010.10.023","article-title":"Exposure to a social stressor alters the structure of the intestinal microbiota: implications for stressor-induced immunomodulation","volume":"25","author":"Bailey","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0050","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1128\/IAI.00862-09","article-title":"Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by citrobacter rodentium","volume":"78","author":"Bailey","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0980","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1152\/ajpregu.00307.2007","article-title":"Repeated social defeat increases the bactericidal activity of splenic macrophages through a toll-like receptor dependent pathway","volume":"293","author":"Bailey","year":"2007","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0060","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jneuroim.2005.09.008","article-title":"Stress induces the translocation of cutaneous and gastrointestinal microflora to secondary lymphoid organs of C57BL\/6 mice","volume":"171","author":"Bailey","year":"2006","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0065","first-page":"414","article-title":"Prenatal stress alters bacterial colonization of the gut in infant monkeys","volume":"38","author":"Bailey","year":"2004","journal-title":"J. Pediatr. Gastroenterol. Nutr."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0070","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0016-5085(87)90319-2","article-title":"Effect of psychological stress on salt and water transport in the human jejunum","volume":"93","author":"Barclay","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0075","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/0016-5085(88)90558-6","article-title":"Effect of cold-induced pain on salt and water transport in the human jejunum","volume":"94","author":"Barclay","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0080","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.yfrne.2007.02.001","article-title":"Social stress, immune functions and disease in rodents","volume":"28","author":"Bartolomucci","year":"2007","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0085","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1136\/gut.43.2.256","article-title":"Level of chronic life stress predicts clinical outcome in irritable bowel syndrome","volume":"43","author":"Bennett","year":"1998","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0090","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1038\/ajg.2010.140","article-title":"A prospective population-based study of triggers of symptomatic flares in IBD","volume":"105","author":"Bernstein","year":"2010","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0095","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0306-4522(98)00742-8","article-title":"Behavioral, neuroendocrine and serotonergic consequences of single social defeat and repeated fluoxetine pretreatment in the Lewis rat strain","volume":"92","author":"Berton","year":"1999","journal-title":"Neuroscience"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0985","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1136\/gut.2007.134817","article-title":"Predicting relapse in Crohn's disease: a biopsychosocial model","volume":"57","author":"Bitton","year":"2008","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0105","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1111\/j.1572-0241.2003.07717.x","article-title":"Psychosocial determinants of relapse in ulcerative colitis: a longitudinal study","volume":"98","author":"Bitton","year":"2003","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0110","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/S0952-7915(99)00032-1","article-title":"Animal models of mucosal inflammation and their relation to human inflammatory bowel disease","volume":"11","author":"Blumberg","year":"1999","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0115","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1001\/jama.285.5.643","article-title":"Prospects for research in inflammatory bowel disease","volume":"285","author":"Blumberg","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0120","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1084\/jem.188.10.1929","article-title":"Oxazolone colitis: a murine model of T helper cell type 2 colitis treatable with antibodies to interleukin 4","volume":"188","author":"Boirivant","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0125","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1080\/00016350152509265","article-title":"Inflammatory bowel disease: clinics and pathology. Do inflammatory bowel disease and periodontal disease have similar immunopathogeneses?","volume":"59","author":"Brandtzaeg","year":"2001","journal-title":"Acta Odontol. Scand."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0130","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1159\/000056219","article-title":"Psychobiological aspects of atopic dermatitis: an overview","volume":"70","author":"Buske-Kirschbaum","year":"2001","journal-title":"Psychother. Psychosom."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0135","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.peptides.2003.11.005","article-title":"The anti-inflammatory effect of leptin on experimental colitis: involvement of endogenous glucocorticoids","volume":"25","author":"Cakir","year":"2004","journal-title":"Peptides"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0140","first-page":"1364","article-title":"The relationship between personality, stress and disease activity in ulcerative colitis","volume":"90","author":"Campbell","year":"1986","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0145","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1001\/archinte.162.10.1157","article-title":"Intimate partner violence and physical health consequences","volume":"162","author":"Campbell","year":"2002","journal-title":"Arch. Int. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0150","series-title":"The Wisdom of the Body","author":"Cannon","year":"1939"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0155","doi-asserted-by":"crossref","first-page":"G884","DOI":"10.1152\/ajpgi.1996.271.5.G884","article-title":"Acute stress causes mucin release from rat colon: role of corticotropin releasing factor and mast cells","volume":"271","author":"Castagliuolo","year":"1996","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0160","doi-asserted-by":"crossref","first-page":"G1094","DOI":"10.1152\/ajpgi.1998.274.6.G1094","article-title":"Colonic mucin release in response to immobilization stress is mast cell dependent","volume":"274","author":"Castagliuolo","year":"1998","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0165","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1196\/annals.1410.037","article-title":"Vasopressin does not mediate hypersensitivity of the hypothalamic pituitary adrenal axis during chronic stress","volume":"1148","author":"Chen","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0170","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1111\/j.1476-5381.1995.tb15089.x","article-title":"Evidence for arginine vasopressin as the primary activator of the HPA axis during adjuvant-induced arthritis","volume":"116","author":"Chowdrey","year":"1995","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0175","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1056\/NEJM199108293250903","article-title":"Psychological stress and susceptibility to the common cold","volume":"325","author":"Cohen","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0180","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1001\/archfami.9.5.451","article-title":"Physical health consequences of physical and psychological intimate partner violence","volume":"9","author":"Coker","year":"2000","journal-title":"Arch. Family Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0185","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1016\/S0016-5085(96)70012-4","article-title":"Previous inflammation alters the response of the rat colon to stress","volume":"111","author":"Collins","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0190","first-page":"238","article-title":"Clinicopathologic study of dextran sulfate sodium experimental murine colitis","volume":"69","author":"Cooper","year":"1993","journal-title":"Lab. Invest."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/YCO.0b013e3280117733","article-title":"Animal models of mood disorders: recent developments","volume":"20","author":"Cryan","year":"2007","journal-title":"Curr. Opin. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0200","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/S1054-3589(10)58016-5","article-title":"GABAB receptors and depression. Current status","volume":"58","author":"Cryan","year":"2010","journal-title":"Adv. Pharmacol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0205","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1017\/S0950268803008410","article-title":"The infectious intestinal disease study of England: a prospective evaluation of symptoms and health care use after an acute episode","volume":"130","author":"Cumberland","year":"2003","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0210","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1055\/s-2006-926796","article-title":"Aminosalicylates and steroids in the treatment of chronic inflammatory bowel diseases\u2014consensus paper of the Working Group for Chronic Inflammatory Bowel Diseases of the OGGH","volume":"44","author":"Dejaco","year":"2006","journal-title":"Z. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0215","first-page":"449","article-title":"In vivo effects of recombinant human interleukin-10 on lymphocyte phenotypes and leukocyte activation markers in inflammatory bowel disease","volume":"48","author":"Dejaco","year":"2000","journal-title":"J. Invest. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0220","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0889-1591(02)00036-3","article-title":"Stress-induced augmentation of immune function\u2014the role of stress hormones, leukocyte trafficking, and cytokines","volume":"16","author":"Dhabhar","year":"2002","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0225","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.4049\/jimmunol.156.7.2608","article-title":"Stress-induced enhancement of antigen-specific cell-mediated immunity","volume":"156","author":"Dhabhar","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0230","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1006\/brbi.1997.0508","article-title":"Acute stress enhances while chronic stress suppresses cell-mediated immunity in vivo: a potential role for leukocyte trafficking","volume":"11","author":"Dhabhar","year":"1997","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0235","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1073\/pnas.96.3.1059","article-title":"Enhancing versus suppressive effects of stress hormones on skin immune function","volume":"96","author":"Dhabhar","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0240","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.3748\/wjg.v10.i16.2373","article-title":"Intestinal barrier damage caused by trauma and lipopolysaccharide","volume":"10","author":"Ding","year":"2004","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0245","doi-asserted-by":"crossref","first-page":"S24","DOI":"10.1007\/BF01296968","article-title":"Is the cotton-topped tamarin a model for behavioral research?","volume":"30","author":"Drossman","year":"1985","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0250","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1080\/08964289.1991.9937553","article-title":"Relevance of major stress events as an indicator of disease activity prevalence in inflammatory bowel disease","volume":"17","author":"Duffy","year":"1991","journal-title":"Behav. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0255","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1096\/fj.99-0885hyp","article-title":"Does the failure to acquire helminthic parasites predispose to Crohn's disease?","volume":"14","author":"Elliott","year":"2000","journal-title":"FASEB J."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0260","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.4049\/jimmunol.157.5.2174","article-title":"Hapten-induced model of murine inflammatory bowel disease: mucosa immune responses and protection by tolerance","volume":"157","author":"Elson","year":"1996","journal-title":"J. Immunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0265","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/0016-5085(95)90599-5","article-title":"Experimental models of inflammatory bowel disease","volume":"109","author":"Elson","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0270","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biopsycho.2009.09.006","article-title":"The role of childhood abuse in HPA-axis reactivity in social anxiety disorder: a pilot study","volume":"83","author":"Elzinga","year":"2010","journal-title":"Biol. Psychol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0275","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.psyneuen.2007.10.007","article-title":"Interleukin-1 receptor type 1-deficient mice fail to develop social stress-associated glucocorticoid resistance in the spleen","volume":"33","author":"Engler","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0280","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jneuroim.2005.03.002","article-title":"Tissue-specific alterations in the glucocorticoid sensitivity of immune cells following repeated social defeat in mice","volume":"163","author":"Engler","year":"2005","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0285","doi-asserted-by":"crossref","first-page":"R905","DOI":"10.1152\/ajpregu.2000.278.4.R905","article-title":"Systemic bacterial invasion induced by sleep deprivation","volume":"278","author":"Everson","year":"2000","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0290","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0016-5085(03)01057-6","article-title":"Stress-induced disruption of colonic epithelial barrier: role of interferon-gamma and myosin light chain kinase in mice","volume":"125","author":"Ferrier","year":"2003","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0295","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/S0016-5085(98)70381-6","article-title":"Inflammatory bowel disease: etiology and pathogenesis","volume":"115","author":"Fiocchi","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0300","first-page":"41","article-title":"The relation between daily stress and Crohn's disease","volume":"1","author":"Garrett","year":"1991","journal-title":"J. Behav. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0305","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1053\/bega.1999.0038","article-title":"The role of psychosocial factors in irritable bowel syndrome","volume":"13","author":"Gaynes","year":"1999","journal-title":"Baillieres Best Pract. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0310","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1080\/10253890701288935","article-title":"Evolution of concepts of stress","volume":"10","author":"Goldstein","year":"2007","journal-title":"Stress"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0315","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1600-0684.1992.tb00623.x","article-title":"Mortality causes of the moustached tamarin (Saguinus mystax) in captivity","volume":"21","author":"Gozalo","year":"1992","journal-title":"J. Med. Primatol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0320","first-page":"G84","article-title":"Stress-induced enhancement of colitis in rats: CRF and arginine vasopressin are not involved","volume":"272","author":"Gue","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0325","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.lfs.2003.12.009","article-title":"Anti-inflammatory effect of acute stress on experimental colitis is mediated by cholecystokinin-B receptors","volume":"75","author":"Gulpinar","year":"2004","journal-title":"Life Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0330","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1749-6632.1995.tb44701.x","article-title":"Evidence for altered control of hypothalamic CRF in immune-mediated diseases","volume":"771","author":"Harbuz","year":"1995","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0335","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1001\/archgenpsychiatry.2008.508","article-title":"Childhood trauma and risk for chronic fatigue syndrome: association with neuroendocrine dysfunction","volume":"66","author":"Heim","year":"2009","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0340","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/S0006-3223(01)01157-X","article-title":"The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies","volume":"49","author":"Heim","year":"2001","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0345","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1126\/science.270.5239.1203","article-title":"Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin","volume":"270","author":"Hermiston","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0350","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0889-857X(05)70167-8","article-title":"Stress and rheumatic diseases","volume":"26","author":"Herrmann","year":"2000","journal-title":"Rheum. Dis. Clin. North Am."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0355","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1128\/aem.31.3.359-375.1976","article-title":"Human fecal flora: variation in bacterial composition within individuals and a possible effect of emotional stress","volume":"31","author":"Holdeman","year":"1976","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0360","doi-asserted-by":"crossref","first-page":"721","DOI":"10.3109\/00365529209011172","article-title":"The intestinal permeability barrier. A hypothesis as to its regulation and involvement in Crohn's disease","volume":"27","author":"Hollander","year":"1992","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0365","doi-asserted-by":"crossref","first-page":"883","DOI":"10.7326\/0003-4819-105-6-883","article-title":"Increased intestinal permeability in patients with Crohn's disease and their relatives. A possible etiologic factor","volume":"105","author":"Hollander","year":"1986","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0370","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.1053\/gast.1997.v112.pm9178676","article-title":"Quantification of the placebo onset in ulcerative colitis","volume":"112","author":"Ilnyckyi","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0375","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.cell.2006.02.016","article-title":"Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer","volume":"124","author":"Karin","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0380","doi-asserted-by":"crossref","first-page":"5931","DOI":"10.1128\/IAI.70.11.5931-5937.2002","article-title":"Intestinal nematode infection ameliorates experimental colitis in mice","volume":"70","author":"Khan","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0385","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/00006842-199505000-00008","article-title":"Psychoneuroimmunology and health consequences: data and shared mechanisms","volume":"57","author":"Kiecolt-Glaser","year":"1995","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0390","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1073\/pnas.93.7.3043","article-title":"Chronic stress alters the immune response to influenza virus vaccine in older adults","volume":"93","author":"Kiecolt-Glaser","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0395","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/S0140-6736(95)92899-5","article-title":"Slowing of wound healing by psychological stress","volume":"346","author":"Kiecolt-Glaser","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0400","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1037\/0003-066X.53.11.1209","article-title":"Psychological influences on surgical recovery. Perspectives from psychoneuroimmunology","volume":"53","author":"Kiecolt-Glaser","year":"1998","journal-title":"Am. Psychol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0405","first-page":"G1037","article-title":"Stress stimulates transepithelial macromolecular uptake in rat jejunum","volume":"275","author":"Kiliaan","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0410","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1254\/fpj.105.145","article-title":"Study on the experimental ulcerative colitis (UC) model induced by dextran sulfate sodium (DSS) in rats (2)","volume":"105","author":"Kimura","year":"1995","journal-title":"Nippon Yakurigaku Zasshi"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0415","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1007\/BF01299867","article-title":"Changes of colonic vasoactive intestinal peptide and cholinergic activity in rats with chemical colitis","volume":"37","author":"Kishimoto","year":"1992","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0420","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1538\/expanim.48.137","article-title":"Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium","volume":"48","author":"Kitajima","year":"1999","journal-title":"Exp. Anim."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0425","first-page":"247","article-title":"Preillness non dietary factors and habits in inflammatory bowel disease","volume":"30","author":"Klein","year":"1998","journal-title":"Ital. J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0430","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2011.02.003","article-title":"Stress revisited: a critical evaluation of the stress concept","author":"Koolhaas","year":"2011","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0435","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1046\/j.1365-2826.1999.00342.x","article-title":"Hyper-reactive hypothalamo\u2013pituitary\u2013adrenocortical axis in rats bred for high anxiety-related behaviour","volume":"11","author":"Landgraf","year":"1999","journal-title":"J. Neuroendocrinol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0440","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1111\/j.1572-0241.2000.02012.x","article-title":"Stress and exacerbation in ulcerative colitis: a prospective study of patients enrolled in remission","volume":"95","author":"Levenstein","year":"2000","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0445","first-page":"1219","article-title":"Physiological stress and disease activity in ulcerative colitis: a multidimensional cross-sectional study","volume":"89","author":"Levenstein","year":"1998","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0450","series-title":"Physiological Mechanisms Controlling Activity of Adrenal Medulla","author":"Lewis","year":"1975"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0455","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1097\/00001574-200001000-00015","article-title":"Chemokines and cytokines in inflammatory bowel disease and their application to disease treatment","volume":"16","author":"Lichtenstein","year":"2000","journal-title":"Curr. Opin. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0460","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1126\/science.1106442","article-title":"Immunity, inflammation, and allergy in the gut","volume":"307","author":"MacDonald","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0465","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0016-5085(85)80126-8","article-title":"Characterization of spontaneous colitis in cotton-top tamarins (Saguinus oedipus) and its response to sulfasalazine","volume":"88","author":"Madara","year":"1985","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0470","series-title":"Pediatric Inflammatory Bowel Disease","article-title":"Puberty and pediatric-onset inflammatory bowel disease","author":"Mamula","year":"2008"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0475","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/00006842-199805000-00025","article-title":"Mucosal wound healing is impaired by examination stress","volume":"60","author":"Marucha","year":"1998","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0480","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1136\/gut.2005.064261","article-title":"Psychological stress in IBD: new insights into pathogenic and therapeutic implications","volume":"54","author":"Mawdsley","year":"2005","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0485","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1159\/000104861","article-title":"The role of psychological stress in inflammatory bowel disease","volume":"13","author":"Mawdsley","year":"2006","journal-title":"Neuroimmunomodulation"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0490","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1016\/0016-5085(93)90638-S","article-title":"Is small intestinal permeability really increased in relatives of patients with Crohn's disease?","volume":"104","author":"May","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0495","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1136\/gut.47.6.861","article-title":"The neurobiology of stress and gastrointestinal disease","volume":"47","author":"Mayer","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0500","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1136\/gut.46.5.595","article-title":"Psychological stress and colitis","volume":"46","author":"Mayer","year":"2000","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0505","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1196\/annals.1314.001","article-title":"Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders","volume":"1032","author":"McEwen","year":"2004","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0510","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/j.1749-6632.1999.tb08103.x","article-title":"Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load","volume":"896","author":"McEwen","year":"1999","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0515","doi-asserted-by":"crossref","first-page":"e8226","DOI":"10.1371\/journal.pone.0008226","article-title":"Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome","volume":"4","author":"McKernan","year":"2009","journal-title":"PLoS ONE"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0520","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0016-5085(98)70636-5","article-title":"Discrimination of site-specific alterations in gastrointestinal permeability in the rat","volume":"114","author":"Meddings","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0525","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1053\/gast.2000.18152","article-title":"Environmental stress-induced gastrointestinal permeability is mediated by endogenous glucocorticoids in the rat","volume":"119","author":"Meddings","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0530","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1210\/en.2004-0416","article-title":"Correlations between hypothalamus\u2013pituitary\u2013adrenal axis parameters depend on age and learning capacity","volume":"146","author":"Meijer","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0535","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1080\/10253890701820166","article-title":"Psychological stress reactivates dextran sulfate sodium-induced chronic colitis in mice","volume":"11","author":"Melgar","year":"2008","journal-title":"Stress"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0540","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/BF02688826","article-title":"A study of the effects of restraint stress on colitis induced by dextran sulphate sodium in singly housed rats","volume":"37","author":"Milde","year":"2002","journal-title":"Integr. Physiol. Behav. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0545","doi-asserted-by":"crossref","first-page":"G1027","DOI":"10.1152\/ajpgi.1999.276.4.G1027","article-title":"Susceptibility of Lewis and Fischer rats to stress-induced worsening of TNB-colitis: protective role of brain CRF","volume":"276","author":"Million","year":"1999","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0550","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/S0016-5085(87)91099-7","article-title":"Survey of the AGA membership relating to patients with functional gastrointestinal disorders","volume":"92","author":"Mitchell","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0555","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0016-5085(89)80079-4","article-title":"Hapten-induced model of chronic inflammation and ulceration in the rat colon","volume":"96","author":"Morris","year":"1989","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0560","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/S0306-4522(99)00433-9","article-title":"Brain oxytocin: differential inhibition of neuroendocrine stress responses and anxiety-related behaviour in virgin, pregnant and lactating rats","volume":"95","author":"Neumann","year":"2000","journal-title":"Neuroscience"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0565","first-page":"30","article-title":"Immunopathogenesis of inflammatory bowel diseases","volume":"71","author":"Neurath","year":"2000","journal-title":"Chirurgia"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0570","doi-asserted-by":"crossref","first-page":"381","DOI":"10.7326\/0003-4819-114-5-381","article-title":"Do life events or depression exacerbate inflammatory bowel disease? A prospective study","volume":"114","author":"North","year":"1991","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0575","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1176\/ajp.147.8.974","article-title":"The relation of ulcerative colitis to psychiatric factors: a review of findings and methods","volume":"147","author":"North","year":"1990","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0580","first-page":"1327","article-title":"Production of experimental ulcerative colitis in hamsters by dextran sulfate sodium and changes in intestinal microflora","volume":"82","author":"Ohkusa","year":"1985","journal-title":"Nippon Shokakibyo Gakkai Zasshi"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0585","first-page":"163","article-title":"Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions","volume":"7","author":"Ohman","year":"2010","journal-title":"Nat. Rev."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0590","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1023\/A:1021616723969","article-title":"Plasma ACTH levels during early, two-way avoidance acquisition in high- and low-avoidance rats (Hatano strains)","volume":"29","author":"Ohta","year":"1999","journal-title":"Behav. Genet."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0595","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/0016-5085(90)90290-H","article-title":"A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice","volume":"98","author":"Okayasu","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0600","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/BF03343838","article-title":"Actual stress, psychopathology and salivary corticol levels in the irritable bowel syndrome (IBS)","volume":"24","author":"Patacchioli","year":"2001","journal-title":"J. Endocrinol. Invest."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0605","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1172\/JCI115047","article-title":"Role of mast cells in ion transport abnormalities associated with intestinal anaphylaxis. Correction of the diminished secretory response in genetically mast cell-deficient W\/Wv mice by bone marrow transplantation","volume":"87","author":"Perdue","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0610","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0928-4257(01)00012-2","article-title":"Reduction of colonic mucus by repeated short-term stress enhances experimental colitis in rats","volume":"95","author":"Pfeiffer","year":"2001","journal-title":"J. Physiol. Paris"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0615","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1056\/NEJM199109263251306","article-title":"Inflammatory bowel disease (1)","volume":"325","author":"Podolsky","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0620","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1056\/NEJM199110033251406","article-title":"Inflammatory bowel disease (2)","volume":"325","author":"Podolsky","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0625","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1056\/NEJMra020831","article-title":"Inflammatory bowel disease","volume":"347","author":"Podolsky","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0630","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0016-5085(85)80127-X","article-title":"Colonic mucin composition in primates. Selective alterations associated with spontaneous colitis in the cotton-top tamarin","volume":"88","author":"Podolsky","year":"1985","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0635","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1097\/00006842-195809000-00006","article-title":"Some experimental observations on gastrointestinal lesions in behaviorally conditioned monkeys","volume":"20","author":"Porter","year":"1958","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0640","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/s00213-004-2134-x","article-title":"Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919)","volume":"180","author":"Post","year":"2005","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0645","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1136\/gut.33.5.687","article-title":"Epidemiological study of ulcerative proctocolitis in Indian migrants and the indigenous population of Leicestershire","volume":"33","author":"Probert","year":"1992","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0650","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1136\/gut.36.5.696","article-title":"South Asian and European colitics show characteristic differences in colonic mucus glycoprotein type and turnover","volume":"36","author":"Probert","year":"1995","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0655","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1038\/13503","article-title":"The role of CD4+ lymphocytes in the susceptibility of mice to stress-induced reactivation of experimental colitis","volume":"5","author":"Qiu","year":"1999","journal-title":"Nat. Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0660","series-title":"Stress, Immune Functions and Health","author":"Rabin","year":"1999"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0665","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1172\/JCI118878","article-title":"Normal luminal bacteria, especially bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27\/Human beta 2 microglobulin transgenic rats","volume":"98","author":"Rath","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0670","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1210\/en.2006-0983","article-title":"Adrenal insufficiency and colonic inflammation after a novel chronic psycho-social stress paradigm in mice: implications and mechanisms","volume":"148","author":"Reber","year":"2007","journal-title":"Endocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0675","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1196\/annals.1410.003","article-title":"Chronic subordinate colony (CSC) housing enhances state anxiety and reduces hypothalamic arginine vasopressin, but not oxytocin, synthesis","volume":"1148","author":"Reber","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0680","doi-asserted-by":"crossref","first-page":"4968","DOI":"10.1210\/en.2006-0347","article-title":"Chronic intermittent psychosocial stress (social defeat\/overcrowding) in mice increases the severity of an acute DSS-induced colitis and impairs regeneration","volume":"147","author":"Reber","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0685","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1080\/10253890701733351","article-title":"Aggravation of DSS-induced colitis after chronic subordinate colony (CSC) housing is partially mediated by adrenal mechanisms","volume":"11","author":"Reber","year":"2008","journal-title":"Int. J. Biol. Stress"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0690","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbi.2011.03.004","article-title":"Mucosal immunosuppression and epithelial barrier defects are key events in murine psychosocial stress-induced colitis","author":"Reber","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0695","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1210\/endo-117-6-2505","article-title":"Two receptor systems for corticosterone in rat brain: microdistribution and differential occupation","volume":"117","author":"Reul","year":"1985","journal-title":"Endocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0700","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1136\/gut.31.2.179","article-title":"Why do patients with ulcerative colitis relapse?","volume":"31","author":"Riley","year":"1990","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0705","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1136\/gut.30.5.623","article-title":"Personality profile and affective state of patients with inflammatory bowel disease","volume":"30","author":"Robertson","year":"1989","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0710","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/00054725-199808000-00002","article-title":"Inflammatory bowel disease: is there any relation between smoking status and disease presentation? European Collaborative IBD Study Group","volume":"4","author":"Russel","year":"1998","journal-title":"Inflamm. Bowel Dis."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0715","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0140-6736(67)91094-X","article-title":"Non-specific ulcerative colitis in Bedouin Arabs","volume":"1","author":"Salem","year":"1967","journal-title":"Lancet"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0720","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s00535-006-1995-7","article-title":"Inflammatory bowel disease: past, present, and future","volume":"42","author":"Sands","year":"2007","journal-title":"J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0725","doi-asserted-by":"crossref","first-page":"G847","DOI":"10.1152\/ajpgi.2000.278.6.G847","article-title":"Chronic stress impairs rat growth and jejunal epithelial barrier function: role of mast cells","volume":"278","author":"Santos","year":"2000","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0730","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/S0016-5085(98)70577-3","article-title":"Release of mast cell mediators into the jejunum by cold pain stress in humans","volume":"114","author":"Santos","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0735","doi-asserted-by":"crossref","first-page":"G391","DOI":"10.1152\/ajpgi.1999.277.2.G391","article-title":"Corticotropin-releasing hormone mimics stress-induced colonic epithelial pathophysiology in the rat","volume":"277","author":"Santos","year":"1999","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0740","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1136\/gut.48.5.630","article-title":"Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat","volume":"48","author":"Santos","year":"2001","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0745","series-title":"Behavioral Endocrinology","first-page":"287","article-title":"Neuroendocrinology of the stress-response","author":"Sapolsky","year":"1992"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0750","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0197-4580(86)90159-4","article-title":"The adrenocortical axis in the aged rat: impaired sensitivity to both fast and delayed feedback inhibition","volume":"7","author":"Sapolsky","year":"1986","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0755","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1210\/edrv-7-3-284","article-title":"The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis","volume":"7","author":"Sapolsky","year":"1986","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0760","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1126\/science.2821621","article-title":"Interleukine-1 stimulates the secretion of hypothalamic corticotropin releasing factor","volume":"238","author":"Sapolsky","year":"1987","journal-title":"Science Wash. DC"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0765","first-page":"55","article-title":"How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions","volume":"21","author":"Sapolsky","year":"2000","journal-title":"Endocr. Rev."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0770","first-page":"G486","article-title":"Cholinergic nerves mediate stress-induced intestinal transport abnormalities in Wistar-Kyoto rats","volume":"273","author":"Saunders","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0775","doi-asserted-by":"crossref","first-page":"G794","DOI":"10.1152\/ajpgi.1994.267.5.G794","article-title":"Acute stressors stimulate ion secretion and increase epithelial permeability in rat intestine","volume":"267","author":"Saunders","year":"1994","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0780","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0014-2999(01)01574-6","article-title":"Peripheral corticotropin-releasing factor induces diarrhea in rats: role of CRF1 receptor in fecal watery excretion","volume":"435","author":"Saunders","year":"2002","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0785","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.autneu.2005.12.002","article-title":"Noradrenergic and cholinergic neural pathways mediate stress-induced reactivation of colitis in the rat","volume":"124","author":"Saunders","year":"2006","journal-title":"Autonom. Neurosci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0790","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1023\/A:1013204612762","article-title":"Physical and psychological stress in rats enhances colonic epithelial permeability via peripheral CRH","volume":"47","author":"Saunders","year":"2002","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0795","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.bbr.2010.08.049","article-title":"The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain","volume":"216","author":"Savignac","year":"2011","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0800","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/j.bbi.2010.04.014","article-title":"Chronic psychosocial stress promotes systemic immune activation and the development of inflammatory Th cell responses","volume":"24","author":"Schmidt","year":"2010","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0805","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/138032a0","article-title":"A syndrome produced by diverse nocous agents","volume":"138","author":"Selye","year":"1936","journal-title":"Nature"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0810","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1080\/0097840X.1975.9940406","article-title":"Confusion and controversy in the stress field","author":"Selye","year":"1975","journal-title":"J. Human Stress"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0815","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/BF01730377","article-title":"Crohn's disease in the Kinneret sub-district, Israel, 1960\u20131990. Incidence and prevalence in different ethnic subgroups","volume":"10","author":"Shapira","year":"1994","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0820","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1046\/j.0007-1323.2001.01909.x","article-title":"Immune therapy in inflammatory bowel disease and models of colitis","volume":"88","author":"Singh","year":"2001","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0825","doi-asserted-by":"crossref","first-page":"G7","DOI":"10.1152\/ajpgi.2001.280.1.G7","article-title":"Stress and the gastrointestinal tract: II. Stress and intestinal barrier function","volume":"280","author":"S\u00f6derholm","year":"2001","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0830","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1053\/gast.2002.36019","article-title":"Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine","volume":"123","author":"S\u00f6derholm","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0835","doi-asserted-by":"crossref","first-page":"G1257","DOI":"10.1152\/ajpgi.00314.2002","article-title":"Neonatal maternal separation predisposes adult rats to colonic barrier dysfunction in response to mild stress","volume":"283","author":"S\u00f6derholm","year":"2002","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0840","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1097\/00003246-199604000-00015","article-title":"Characteristics of the intestinal epithelial barrier during dietary manipulation and glucocorticoid stress","volume":"24","author":"Spitz","year":"1996","journal-title":"Crit. Care Med."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0845","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1073\/pnas.86.7.2374","article-title":"Inflammatory mediator-induced hypothalamic\u2013pituitary\u2013adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats","volume":"86","author":"Sternberg","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0850","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0016-5085(19)33897-1","article-title":"Ulcerative colitis-like lesions in Siamong gibbons","volume":"57","author":"Stout","year":"1969","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0855","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S0165-5728(02)00047-4","article-title":"Uncoupling of the sympathetic nervous system and the hypothalamic\u2013pituitary\u2013adrenal axis in inflammatory bowel disease?","volume":"126","author":"Straub","year":"2002","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0860","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1111\/j.1572-0241.1998.00535.x","article-title":"Association of humoral markers of inflammation and dehydroepiandrosterone sulfate or cortisol serum levels in patients with chronic inflammatory bowel disease","volume":"93","author":"Straub","year":"1998","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0865","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1146\/annurev.immunol.20.100301.064816","article-title":"The immunology of mucosal models of inflammation","volume":"20","author":"Strober","year":"2002","journal-title":"Annu. Rev. Immunol."},{"issue":"Suppl.","key":"10.1016\/j.psyneuen.2011.05.014_bib0870","first-page":"16","article-title":"Role of corticotropin releasing factor receptor subtype 1 in stress-related functional colonic alterations: implications in irritable bowel syndrome","author":"Tache","year":"2002","journal-title":"Eur. J. Surg."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0875","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1038\/sj.bjp.0705760","article-title":"CRF1 receptor signaling pathways are involved in stress-related alterations of colonic function and viscerosensitivity: implications for irritable bowel syndrome","volume":"141","author":"Tache","year":"2004","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0880","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1440-1746.1992.tb00997.x","article-title":"Inflammatory bowel disease: an uncommon problem in Singapore","volume":"7","author":"Tan","year":"1992","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0885","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1016\/S0140-6736(94)91716-7","article-title":"The placebo in general practice","volume":"344","author":"Thomas","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0890","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1080\/1025389021000048638","article-title":"The brain prolactin system: involvement in stress response adaptations in lactation","volume":"5","author":"Torner","year":"2002","journal-title":"Stress"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0895","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1046\/j.1460-9568.2002.01965.x","article-title":"Increased hypothalamic expression of prolactin in lactation: involvement in behavioural and neuroendocrine stress responses","volume":"15","author":"Torner","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0900","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.psyneuen.2008.03.013","article-title":"Mice selected for high versus low stress reactivity: a new animal model for affective disorders","volume":"33","author":"Touma","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0905","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1038\/nature01321","article-title":"The inflammatory reflex","volume":"420","author":"Tracey","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0910","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1038\/nri2566","article-title":"Reflex control of immunity","volume":"9","author":"Tracey","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0915","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1210\/en.2007-1469","article-title":"Early life stress enhances the vulnerability to chronic psychosocial stress and experimental colitis in adult mice","volume":"144","author":"Veenema","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0920","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1016\/j.bbi.2010.06.002","article-title":"Chronological assessment of mast cell-mediated gut dysfunction and mucosal inflammation in a rat model of chronic psychosocial stress","volume":"24","author":"Vicario","year":"2010","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0925","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.3748\/wjg.v10.i11.1619","article-title":"Risk factors of development of gut-derived bacterial translocation in thermally injured rats","volume":"10","author":"Wang","year":"2004","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0930","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0031-9384(98)00300-X","article-title":"Periodic maternal deprivation induces gender-dependent alterations in behavioral and neuroendocrine responses to emotional stress in adult rats","volume":"66","author":"Wigger","year":"1999","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0935","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1023\/A:1018842210330","article-title":"Colitis and colon cancer in cotton-top tamarins (Saguinus oedipus) living wild in their natural habitat","volume":"43","author":"Wood","year":"1998","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0940","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1023\/A:1005485215128","article-title":"Evidence that colitis is initiated by environmental stress and sustained by fecal factors in the cotton-top tamarin (Saguinus oedipus)","volume":"45","author":"Wood","year":"2000","journal-title":"Dig. Dis. Sci."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0945","doi-asserted-by":"crossref","first-page":"A943","DOI":"10.1016\/0016-5085(95)28077-4","article-title":"Environmental stress as a factor in the etiology of colitis in the cotton-top tamarin","volume":"108","author":"Wood","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0950","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/j.jaci.2004.03.032","article-title":"Chronic caregiver stress and IgE expression, allergen-induced proliferation, and cytokine profiles in a birth cohort predisposed to atopy","volume":"113","author":"Wright","year":"2004","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0955","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1016\/0140-6736(93)90882-H","article-title":"Intestinal permeability and the prediction of relapse in Crohn's disease","volume":"341","author":"Wyatt","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0960","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/0016-5085(95)90017-9","article-title":"CD45RO expression on circulating CD19+ B cells in Crohn's disease correlates with intestinal permeability","volume":"108","author":"Yacyshyn","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0965","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1136\/gut.33.11.1521","article-title":"Occurrence of dysplasia and adenocarcinoma after experimental chronic ulcerative colitis in hamsters induced by dextran sulphate sodium","volume":"33","author":"Yamada","year":"1992","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0970","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/0016-5085(93)91011-6","article-title":"Mucosal injury and inflammation in a model of chronic granulomatous colitis in rats","volume":"104","author":"Yamada","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2011.05.014_bib0975","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/978-1-59745-447-6_9","article-title":"Inflammatory bowel disease: a model of chronic inflammation-induced cancer","volume":"511","author":"Yang","year":"2009","journal-title":"Methods Mol. Biol. (Clifton, NJ)"}],"container-title":["Psychoneuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453011001673?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453011001673?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:37:22Z","timestamp":1759682242000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306453011001673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":195,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S0306453011001673"],"URL":"https:\/\/doi.org\/10.1016\/j.psyneuen.2011.05.014","relation":{},"ISSN":["0306-4530"],"issn-type":[{"value":"0306-4530","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stress and animal models of inflammatory bowel disease\u2014An update on the role of the hypothalamo\u2013pituitary\u2013adrenal axis","name":"articletitle","label":"Article Title"},{"value":"Psychoneuroendocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psyneuen.2011.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}