{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T15:56:36Z","timestamp":1793202996494,"version":"4.5.0"},"reference-count":67,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychoneuroendocrinology"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.psyneuen.2012.03.009","type":"journal-article","created":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T09:23:15Z","timestamp":1334049795000},"page":"1589-1599","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":105,"title":["A review of Atypical depression in relation to the course of depression and changes in HPA axis organization"],"prefix":"10.1016","volume":"37","author":[{"given":"Veronica","family":"O\u2019Keane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Frodl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy G.","family":"Dinan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1\u20132","key":"10.1016\/j.psyneuen.2012.03.009_bib0005","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0167-0115(00)00196-8","article-title":"Vasopressinergic regulation of the hypothalamic\u2013pituitary\u2013adrenal axis: implications for stress adaptation?","volume":"96","author":"Aguilera","year":"2000","journal-title":"Regul. Pept."},{"issue":"2\u20133","key":"10.1016\/j.psyneuen.2012.03.009_bib0010","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jad.2004.05.004","article-title":"Atypical depression: a variant of bipolar II or a bridge between unipolar and bipolar II?","volume":"84","author":"Akiskal","year":"2005","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2012.03.009_bib0015","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1600-0447.2007.00965.x","article-title":"Melancholia and atypical depression in the Zurich study: epidemiology, clinical characteristics, course, comorbidity and personality","volume":"433","author":"Angst","year":"2007","journal-title":"Acta Psychiatr. Scand. Suppl."},{"issue":"2","key":"10.1016\/j.psyneuen.2012.03.009_bib0020","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0165-0327(02)00169-6","article-title":"Toward validation of atypical depression in the community: results of the Zurich cohort study","volume":"72","author":"Angst","year":"2002","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0025","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/10253890701378967","article-title":"HPA axis and sleep: identifying subtypes of major depression","volume":"11","author":"Antonijevic","year":"2008","journal-title":"Stress"},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.psyneuen.2005.04.004","article-title":"Depressive disorders \u2013 is it time to endorse different pathophysiologies?","volume":"31","author":"Antonijevic","year":"2006","journal-title":"Psychoneuroendocrinology"},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0035","first-page":"244","article-title":"Is atypical depression a moderate severity depression? A 536-case study","volume":"24","author":"Benazzi","year":"1999","journal-title":"J. Psychiatry Neurosci."},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0040","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0165-1781(99)00035-9","article-title":"Prevalence and clinical features of atypical depression in depressed outpatients: a 467-case study","volume":"86","author":"Benazzi","year":"1999","journal-title":"Psychiatry Res."},{"issue":"4","key":"10.1016\/j.psyneuen.2012.03.009_bib0045","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1001\/archgenpsychiatry.2010.18","article-title":"Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response","volume":"67","author":"Binder","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"issue":"12","key":"10.1016\/j.psyneuen.2012.03.009_bib0050","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1038\/ng1479","article-title":"Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment","volume":"36","author":"Binder","year":"2004","journal-title":"Nat. Genet."},{"key":"10.1016\/j.psyneuen.2012.03.009_bib0055","article-title":"Epidemiology of major depression with atypical features: results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)","author":"Blanco","year":"2011","journal-title":"J. Clin. Psychiatry"},{"issue":"3 Pt 1","key":"10.1016\/j.psyneuen.2012.03.009_bib0060","first-page":"E295","article-title":"Vasopressin regulates human sleep by reducing rapid-eye-movement sleep","volume":"262","author":"Born","year":"1992","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.psyneuen.2012.03.009_bib0065","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1749-6632.2009.04981.x","article-title":"Effects of glucocorticoids on mood, memory, and the hippocampus. Treatment and preventive therapy","volume":"1179","author":"Brown","year":"2009","journal-title":"Ann. N.Y. Acad. Sci."},{"issue":"4","key":"10.1016\/j.psyneuen.2012.03.009_bib0070","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0165-0327(95)00026-J","article-title":"Contrasting neuroendocrine responses in depression and chronic fatigue syndrome","volume":"34","author":"Cleare","year":"1995","journal-title":"J. Affect. Disord."},{"issue":"12","key":"10.1016\/j.psyneuen.2012.03.009_bib0075","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1001\/archpsyc.1984.01790230064010","article-title":"The clinician's illusion","volume":"41","author":"Cohen","year":"1984","journal-title":"Arch. Gen. Psychiatry"},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0080","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1017\/S0033291703001004","article-title":"Further neuroendocrine evidence of enhanced vasopressin V3 receptor responses in melancholic depression","volume":"34","author":"Dinan","year":"2004","journal-title":"Psychol. Med."},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0085","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1469-7580.2005.00443.x","article-title":"Anatomy of melancholia: focus on hypothalamic\u2013pituitary\u2013adrenal axis overactivity and the role of vasopressin","volume":"207","author":"Dinan","year":"2005","journal-title":"J. Anat."},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0090","first-page":"912","article-title":"The longitudinal course of psychopathology in Cushing's syndrome after correction of hypercortisolism","volume":"82","author":"Dorn","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0095","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1046\/j.1471-4159.1997.69010144.x","article-title":"Impact of corticotropin-releasing hormone on extracellular norepinephrine in prefrontal cortex after chronic cold stress","volume":"69","author":"Finlay","year":"1997","journal-title":"J. Neurochem."},{"issue":"5881","key":"10.1016\/j.psyneuen.2012.03.009_bib0100","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/299355a0","article-title":"Corticotropin releasing activity of the new CRF is potentiated several times by vasopressin","volume":"299","author":"Gillies","year":"1982","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0105","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1038\/sj.mp.4001032","article-title":"Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH\/NE states","volume":"7","author":"Gold","year":"2002","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2012.03.009_bib0110","article-title":"Dynamically changing effects of corticosteroids on human hippocampal and prefrontal processing","author":"Henckens","year":"2011","journal-title":"Hum. Brain Mapp."},{"issue":"2\u20133","key":"10.1016\/j.psyneuen.2012.03.009_bib0115","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jad.2004.07.003","article-title":"Depression with atypical features in a sample of primary care outpatients: prevalence, specific characteristics and consequences","volume":"83","author":"Henkel","year":"2004","journal-title":"J. Affect. Disord."},{"issue":"4","key":"10.1016\/j.psyneuen.2012.03.009_bib0120","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0022-3956(94)90017-5","article-title":"The combined dexamethasone\/CRH test: a refined laboratory test for psychiatric disorders","volume":"28","author":"Heuser","year":"1994","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.psyneuen.2012.03.009_bib0125","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.brainres.2008.08.018","article-title":"Differential effects of imipramine and phenelzine on corticosteroid receptor gene expression in mouse brain: potential relevance to antidepressant response","volume":"1238","author":"Heydendael","year":"2008","journal-title":"Brain Res."},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0130","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.jpsychires.2005.07.008","article-title":"Presenting characteristics of depressed outpatients as a function of recurrence: preliminary findings from the STAR*D clinical trial","volume":"40","author":"Hollon","year":"2006","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.psyneuen.2012.03.009_bib0135","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.brainres.2007.07.100","article-title":"Corticotropin-releasing hormone receptors in the medial prefrontal cortex regulate hypothalamic\u2013pituitary\u2013adrenal activity and anxiety-related behavior regardless of prior stress experience","volume":"1186","author":"Jaferi","year":"2007","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0140","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/da.20001","article-title":"Atypical depression, atypical temperament and a differential antidepressant response to fluoxetine and nortriptyline","volume":"19","author":"Joyce","year":"2004","journal-title":"Depress. Anxiety"},{"issue":"4","key":"10.1016\/j.psyneuen.2012.03.009_bib0145","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1192\/bjp.bp.108.050278","article-title":"Prednisolone suppression test in depression: prospective study of the role of HPA axis dysfunction in treatment resistance","volume":"194","author":"Juruena","year":"2009","journal-title":"Br. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.psyneuen.2012.03.009_bib0150","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1016\/S0196-9781(01)00399-0","article-title":"Corticotropin-releasing hormone in depression and post-traumatic stress disorder","volume":"22","author":"Kasckow","year":"2001","journal-title":"Peptides"},{"issue":"4","key":"10.1016\/j.psyneuen.2012.03.009_bib0155","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.psyneuen.2010.07.024","article-title":"Common functional mineralocorticoid receptor polymorphisms modulate the cortisol awakening response: interaction with SSRIs","volume":"36","author":"Klok","year":"2011","journal-title":"Psychoneuroendocrinology"},{"issue":"12","key":"10.1016\/j.psyneuen.2012.03.009_bib0160","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.biopsych.2007.10.026","article-title":"The FKBP5-gene in depression and treatment response\u2014an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort","volume":"63","author":"Lekman","year":"2008","journal-title":"Biol. Psychiatry"},{"issue":"7","key":"10.1016\/j.psyneuen.2012.03.009_bib0165","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1176\/ajp.154.7.934","article-title":"Reversed neurovegetative symptoms of depression: a community study of Ontario","volume":"154","author":"Levitan","year":"1997","journal-title":"Am. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0170","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1139\/jpn.0205","article-title":"Low-dose dexamethasone challenge in women with atypical major depression: pilot study","volume":"27","author":"Levitan","year":"2002","journal-title":"J. Psychiatry Neurosci."},{"issue":"2","key":"10.1016\/j.psyneuen.2012.03.009_bib0175","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1001\/archpsyc.1988.01800260037004","article-title":"Antidepressant specificity in atypical depression","volume":"45","author":"Liebowitz","year":"1988","journal-title":"Arch. Gen. Psychiatry"},{"issue":"6","key":"10.1016\/j.psyneuen.2012.03.009_bib0180","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1111\/j.1365-2826.2008.01711.x","article-title":"The neuroendocrinology of stress: a never ending story","volume":"20","author":"Lightman","year":"2008","journal-title":"J. Neuroendocrinol."},{"issue":"2","key":"10.1016\/j.psyneuen.2012.03.009_bib0185","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.neulet.2006.12.013","article-title":"Association study of corticotropin-releasing hormone receptor1 gene polymorphisms and antidepressant response in major depressive disorders","volume":"414","author":"Liu","year":"2007","journal-title":"Neurosci. Lett."},{"issue":"10","key":"10.1016\/j.psyneuen.2012.03.009_bib0190","doi-asserted-by":"crossref","first-page":"4351","DOI":"10.1210\/endo.138.10.5446","article-title":"Emergence of an isolated arginine vasopressin (AVP) response to stress after repeated restraint: a study of both AVP and corticotropin-releasing hormone messenger ribonucleic acid (RNA) and heteronuclear RNA","volume":"138","author":"Ma","year":"1997","journal-title":"Endocrinology"},{"issue":"9","key":"10.1016\/j.psyneuen.2012.03.009_bib0195","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.euroneuro.2011.03.002","article-title":"Antidepressant use and salivary cortisol in depressive and anxiety disorders","volume":"21","author":"Manthey","year":"2011","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.psyneuen.2012.03.009_bib0200","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/j.1749-6632.2009.05331.x","article-title":"Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disease","volume":"1186","author":"McEwen","year":"2010","journal-title":"Ann. N.Y. Acad. Sci."},{"issue":"2\u20133","key":"10.1016\/j.psyneuen.2012.03.009_bib0205","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0165-1781(96)02781-3","article-title":"Biological and clinical validation of atypical depression?","volume":"60","author":"McGinn","year":"1996","journal-title":"Psychiatry Res."},{"issue":"8","key":"10.1016\/j.psyneuen.2012.03.009_bib0210","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1017\/S0033291704002806","article-title":"Co-morbidity and stability of melancholic features in DSM-IV major depressive disorder","volume":"34","author":"Melartin","year":"2004","journal-title":"Psychol. Med."},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0215","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0022-3956(87)90028-8","article-title":"Stimulation of the pituitary\u2013adrenal axis with arginine vasopressin in patients with depression","volume":"21","author":"Meller","year":"1987","journal-title":"J. Psychiatr. Res."},{"issue":"10","key":"10.1016\/j.psyneuen.2012.03.009_bib0220","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1038\/nn1123","article-title":"Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress","volume":"6","author":"Muller","year":"2003","journal-title":"Nat. Neurosci."},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0225","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/sj.npp.1300071","article-title":"Cerebrospinal fluid corticotropin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: a multiple regression analysis","volume":"28","author":"Newport","year":"2003","journal-title":"Neuropsychopharmacology"},{"issue":"12","key":"10.1016\/j.psyneuen.2012.03.009_bib0230","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.biopsych.2005.04.049","article-title":"Changes in hypothalamic\u2013pituitary\u2013adrenal axis measures after vagus nerve stimulation therapy in chronic depression","volume":"58","author":"O\u2019Keane","year":"2005","journal-title":"Biol. Psychiatry"},{"issue":"11","key":"10.1016\/j.psyneuen.2012.03.009_bib0235","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1111\/j.1365-2826.2011.02139.x","article-title":"Changes in the maternal hypothalamic\u2013pituitary\u2013adrenal axis during the early puerperium may be related to the postpartum \u2018Blues\u2019","volume":"23","author":"O\u2019Keane","year":"2011","journal-title":"J. Neuroendocrinol."},{"issue":"9","key":"10.1016\/j.psyneuen.2012.03.009_bib0240","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1176\/appi.ajp.159.9.1470","article-title":"Atypical depression: a reappraisal","volume":"159","author":"Parker","year":"2002","journal-title":"Am. J. Psychiatry"},{"issue":"5","key":"10.1016\/j.psyneuen.2012.03.009_bib0245","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.psyneuen.2010.10.002","article-title":"Discrimination between patients with melancholic depression and healthy controls: comparison between 24-h cortisol profiles, the DST and the Dex\/CRH test","volume":"36","author":"Paslakis","year":"2011","journal-title":"Psychoneuroendocrinology"},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0250","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s00213-002-1094-2","article-title":"The effects of sub-chronic administration of hydrocortisone on hormonal and psychological responses to L-tryptophan in normal male volunteers","volume":"163","author":"Porter","year":"2002","journal-title":"Psychopharmacology (Berl)"},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0255","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1001\/archpsyc.59.1.70","article-title":"Partial validation of the atypical features subtype of major depressive disorder","volume":"59","author":"Posternak","year":"2002","journal-title":"Arch. Gen. Psychiatry"},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0260","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1210\/jcem-69-3-600","article-title":"Blunted adrenocorticotropin but normal beta-endorphin release after human corticotropin-releasing hormone administration in depression","volume":"69","author":"Rupprecht","year":"1989","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.psyneuen.2012.03.009_bib0265","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s004410051173","article-title":"Dynamic changes in the immunoreactivity of neuropeptide systems of the suprachiasmatic nuclei in golden hamsters during the sleep\u2013wake cycle","volume":"294","author":"Schilling","year":"1998","journal-title":"Cell Tissue Res."},{"issue":"1","key":"10.1016\/j.psyneuen.2012.03.009_bib0270","doi-asserted-by":"crossref","first-page":"e4324","DOI":"10.1371\/journal.pone.0004324","article-title":"The combined dexamethasone\/CRH Test (DEX\/CRH test) and prediction of acute treatment response in major depression","volume":"4","author":"Schule","year":"2009","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.psyneuen.2012.03.009_bib0275","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1097\/PSY.0b013e31820ad12b","article-title":"Depression and hypothalamic\u2013pituitary\u2013adrenal activation: a quantitative summary of four decades of research","volume":"73","author":"Stetler","year":"2011","journal-title":"Psychosom. Med."},{"issue":"13","key":"10.1016\/j.psyneuen.2012.03.009_bib0280","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1038\/npp.2009.99","article-title":"DSM-IV depression with atypical features: is it valid?","volume":"34","author":"Stewart","year":"2009","journal-title":"Neuropsychopharmacology"},{"issue":"13","key":"10.1016\/j.psyneuen.2012.03.009_bib0285","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.1038\/npp.2009.100","article-title":"Atypical depression: useful concept, but it's time to revise the DSM-IV criteria","volume":"34","author":"Thase","year":"2009","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.psyneuen.2012.03.009_bib0290","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/520","article-title":"Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1","volume":"19","author":"Timpl","year":"1998","journal-title":"Nat. Genet."},{"issue":"4","key":"10.1016\/j.psyneuen.2012.03.009_bib0295","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1159\/000126271","article-title":"Effect of metyrapone on the pituitary\u2013adrenal axis in depression: relation to dexamethasone suppressor status","volume":"56","author":"Ur","year":"1992","journal-title":"Neuroendocrinology"},{"issue":"12","key":"10.1016\/j.psyneuen.2012.03.009_bib0300","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1046\/j.1460-9568.2002.02040.x","article-title":"Effects of transgenic overproduction of CRH on anxiety-like behaviour","volume":"15","author":"van Gaalen","year":"2002","journal-title":"Eur. J. Neurosci."},{"issue":"3","key":"10.1016\/j.psyneuen.2012.03.009_bib0305","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/S0006-3223(97)80433-7","article-title":"Plasma arginine vasopressin and motor activity in major depression","volume":"43","author":"van Londen","year":"1998","journal-title":"Biol. Psychiatry"},{"issue":"6","key":"10.1016\/j.psyneuen.2012.03.009_bib0310","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archgenpsychiatry.2009.50","article-title":"Major depressive disorder and hypothalamic\u2013pituitary\u2013adrenal axis activity: results from a large cohort study","volume":"66","author":"Vreeburg","year":"2009","journal-title":"Arch. Gen. Psychiatry"},{"issue":"6","key":"10.1016\/j.psyneuen.2012.03.009_bib0315","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1017\/S0033291702005998","article-title":"Hypothalamic\u2013pituitary\u2013adrenal axis function in patients with chronic depression","volume":"32","author":"Watson","year":"2002","journal-title":"Psychol. Med."},{"issue":"4","key":"10.1016\/j.psyneuen.2012.03.009_bib0335","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.jpsychires.2005.08.001","article-title":"Post-dexamethasone arginine vasopressin levels in patients with severe mood disorders","volume":"40","author":"Watson","year":"2006","journal-title":"J. Psychiatr. Res."},{"issue":"6","key":"10.1016\/j.psyneuen.2012.03.009_bib0320","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0006-3223(94)00153-T","article-title":"Evidence against changes in corticotroph CRF receptors in depressed patients","volume":"37","author":"Young","year":"1995","journal-title":"Biol. Psychiatry"},{"issue":"2","key":"10.1016\/j.psyneuen.2012.03.009_bib0325","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0893-133X(00)00236-0","article-title":"Twenty-four-hour ACTH and cortisol pulsatility in depressed women","volume":"25","author":"Young","year":"2001","journal-title":"Neuropsychopharmacology"},{"issue":"8","key":"10.1016\/j.psyneuen.2012.03.009_bib0330","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1001\/archpsyc.1991.01810320017003","article-title":"Loss of glucocorticoid fast feedback in depression","volume":"48","author":"Young","year":"1991","journal-title":"Arch. Gen. Psychiatry"}],"container-title":["Psychoneuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453012000959?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453012000959?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:39:34Z","timestamp":1759682374000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306453012000959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":67,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0306453012000959"],"URL":"https:\/\/doi.org\/10.1016\/j.psyneuen.2012.03.009","relation":{},"ISSN":["0306-4530"],"issn-type":[{"value":"0306-4530","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A review of Atypical depression in relation to the course of depression and changes in HPA axis organization","name":"articletitle","label":"Article Title"},{"value":"Psychoneuroendocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psyneuen.2012.03.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}