{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T03:39:20Z","timestamp":1784864360955,"version":"3.55.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,4,1]],"date-time":"2013-04-01T00:00:00Z","timestamp":1364774400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychoneuroendocrinology"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1016\/j.psyneuen.2012.07.014","type":"journal-article","created":{"date-parts":[[2012,8,9]],"date-time":"2012-08-09T06:15:39Z","timestamp":1344492939000},"page":"542-551","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"title":["Inhibition of 5\u03b1-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL\/6 mice"],"prefix":"10.1016","volume":"38","author":[{"given":"Roberto","family":"Frau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliano","family":"Pillolla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Bini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Tambaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Devoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Bortolato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psyneuen.2012.07.014_bib0005","doi-asserted-by":"crossref","first-page":"4823","DOI":"10.1523\/JNEUROSCI.16-16-04823.1996","article-title":"Dopaminergic regulation of progesterone receptors: brain D5 dopamine receptors mediate induction of lordosis by D1-like agonists in rats","volume":"16","author":"Apostolakis","year":"1996","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0010","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1038\/sj.npp.1300940","volume":"31","author":"Bardin","year":"2006","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0015","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/S0306-4530(98)00071-7","article-title":"Neurosteroids: a novel function of the brain","volume":"23","author":"Baulieu","year":"1998","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0020","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0166-4328(05)80072-5","article-title":"Behavioural differences between artificially selected aggressive and non-aggressive mice: response to apomorphine","volume":"43","author":"Benus","year":"1991","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0025","series-title":"Proceedings of the 22nd ECNP Congress","article-title":"Blockade of 5-alpha reductase reduces compulsive behaviors in mice","author":"Bini","year":"2009"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0030","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/0006-8993(89)91368-1","article-title":"Enhanced behavioral stereotypies elicited by intrastriatal injection D1 and D2 dopamine agonists in intact rats","volume":"504","author":"Bordi","year":"1989","journal-title":"Brain Res."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0035","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/sj.npp.1300547","article-title":"Activation of D1, but not D2 receptors potentiates dizocilpine-mediated disruption of prepulse inhibition of the startle","volume":"30","author":"Bortolato","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0040","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1176\/appi.ajp.2007.07060978","article-title":"Treatment of Tourette's syndrome with finasteride","volume":"164","author":"Bortolato","year":"2007","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0045","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.1038\/npp.2008.39","article-title":"Antipsychotic-like properties of 5-alpha-reductase inhibitors","volume":"33","author":"Bortolato","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0050","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1001\/archpsyc.1990.01810140081011","article-title":"Sensorimotor gating and schizophrenia. Human and animal model studies","volume":"47","author":"Braff","year":"1990","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0055","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0920-9964(00)00139-0","article-title":"Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia","volume":"49","author":"Braff","year":"2001","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0060","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0014-2999(86)90588-1","article-title":"Obligatory D1\/D2 receptor interaction in the generation of dopamine agonist related behaviors","volume":"131","author":"Braun","year":"1986","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0065","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1038\/sj.npp.1301222","article-title":"Sensorimotor gating and dopamine function in postpartum rats","volume":"32","author":"Byrnes","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0070","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0006-3223(95)00101-8","article-title":"Sensorimotor gating in boys with Tourette's syndrome and ADHD: preliminary results","volume":"39","author":"Castellanos","year":"1996","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0075","doi-asserted-by":"crossref","first-page":"8506","DOI":"10.1523\/JNEUROSCI.23-24-08506.2003","article-title":"Distinct roles of D1 and D5 dopamine receptors in motor activity and striatal synaptic plasticity","volume":"23","author":"Centonze","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0365","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0006-3223(94)90060-4","article-title":"Enhanced stress responsivity of Tourette syndrome patients undergoing lumbar puncture","volume":"36","author":"Chappell","year":"1994","journal-title":"Biol. Psychiatry."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0370","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.psyneuen.2008.03.014","article-title":"Examining cortisol rhythmicity and responsivity to stress in children with Tourette syndrome","volume":"33","author":"Corbett","year":"2008","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0085","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/0006-8993(86)90810-3","article-title":"Differential effects of dopamine agonists on acoustically and electrically elicited startle responses: comparison to effects of strychnine","volume":"371","author":"Davis","year":"1986","journal-title":"Brain Res."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0090","doi-asserted-by":"crossref","unstructured":"Devoto, P., Frau, R., Bini, V., Pillolla, G., Saba, P., Flore, G., Corona, M., Marrosu, F., Bortolato, M. Inhibition of 5alpha-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation. Psychoneuroendocrinology, http:\/\/dx.doi.org\/10.1016\/j.psyneuen.2011.09.018, in press.","DOI":"10.1016\/j.psyneuen.2011.09.018"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0095","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1515\/REVNEURO.1994.5.1.27","article-title":"Modulation of brain dopamine transmission by sex steroids","volume":"5","author":"Di Paolo","year":"1994","journal-title":"Rev. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0100","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1038\/sj.npp.1301657","article-title":"Contributions of dopamine D1, D2, and D3 receptor subtypes to the disruptive effects of cocaine on prepulse inhibition in mice","volume":"33","author":"Doherty","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0105","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.neuropharm.2006.10.015","article-title":"Neurosteroid dehydroepiandrosterone sulfate enhances spontaneous glutamate release in rat prelimbic cortex through activation of dopamine D1 and sigma-1 receptor","volume":"52","author":"Dong","year":"2007","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0110","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fendo.2012.00004","article-title":"Regulation of neurosteroid biosynthesis by neurotransmitters and neuropeptides","volume":"3","author":"Do Rego","year":"2012","journal-title":"Front. Endocrinol."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0115","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.pbb.2006.06.016","article-title":"Neurosteroids, neuroactive steroids, and symptoms of affective disorders","volume":"84","author":"Dubrovsky","year":"2006","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0125","doi-asserted-by":"crossref","first-page":"7349","DOI":"10.1523\/JNEUROSCI.6182-10.2011","article-title":"Contrasting roles for dopamine D1 and D2 receptor subtypes in the dorsomedial striatum but not the nucleus accumbens core during behavioral inhibition in the stop-signal task in rats","volume":"31","author":"Eagle","year":"2011","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0130","doi-asserted-by":"crossref","first-page":"3525","DOI":"10.2174\/138161208786848838","article-title":"Neuroactive steroids as endogenous modulators of anxiety","volume":"14","author":"Eser","year":"2008","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0135","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.bbr.2009.09.028","article-title":"Infusions of anti-sense oligonucleotides for DARPP-32 to the ventral tegmental area reduce effects of progesterone- and a dopamine type 1-like receptor agonist to facilitate lordosis","volume":"206","author":"Frye","year":"2010","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0140","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/j.bbamcr.2010.08.005","article-title":"Sigma-1 receptors amplify dopamine D1 receptor signaling at presynaptic sites in the prelimbic cortex","volume":"1803","author":"Fu","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0145","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0022-3565(24)36980-0","article-title":"Characterization of unconditioned behavioral effects of dopamine D3\/D2 receptor agonists","volume":"283","author":"Geter-Douglass","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0150","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s002130100811","article-title":"Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review","volume":"156","author":"Geyer","year":"2001","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0155","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1017\/S1092852900015650","article-title":"The ventral striatum as an interface between the limbic and motor systems","volume":"12","author":"Groenewegen","year":"2007","journal-title":"CNS Spectr."},{"issue":"Suppl. 2","key":"10.1016\/j.psyneuen.2012.07.014_bib0160","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0306-4530(02)00125-7","article-title":"Gender differences in schizophrenia","author":"H\u00e4fner","year":"2003","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0165","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/(SICI)1098-2396(199705)26:1<81::AID-SYN9>3.0.CO;2-A","article-title":"DA D1- and DA D2-like agonist effects on motor activity of C57 mice: differences compared to rats","volume":"26","author":"Halberda","year":"1997","journal-title":"Synapse"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0175","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/BF02245567","article-title":"D1 and D2 dopamine receptor antagonists reverse prepulse inhibition deficits in an animal model of schizophrenia","volume":"115","author":"Hoffman","year":"1994","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0180","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1037\/0735-7044.115.5.1129","article-title":"Behavioral characterization of dopamine D5 receptor null mutant mice","volume":"115","author":"Holmes","year":"2001","journal-title":"Behav. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0185","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.brainres.2007.07.009","article-title":"Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice","volume":"1169","author":"Kalueff","year":"2007","journal-title":"Brain Res."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0375","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0091-3057(99)00167-7","article-title":"Gender differences in brain and behavior: hormonal and neural bases","volume":"64","author":"Kelly","year":"1999","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0195","doi-asserted-by":"crossref","first-page":"5644","DOI":"10.1523\/JNEUROSCI.19-13-05644.1999","article-title":"Rat strain differences in the ability to disrupt sensorimotor gating are limited to the dopaminergic system, specific to prepulse inhibition, and unrelated to changes in startle amplitude or nucleus accumbens dopamine receptor sensitivity","volume":"19","author":"Kinney","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0200","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1055\/s-2008-1058110","article-title":"Improvement of general symptoms in a chronic psychotic patient treated with finasteride: case report","volume":"41","author":"Koethe","year":"2008","journal-title":"Pharmacopsychiatry"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0205","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0006-8993(96)00392-7","article-title":"Cerebrocortical Fos expression following dopaminergic stimulation: D1\/D2 synergism and its breakdown","volume":"728","author":"LaHoste","year":"1996","journal-title":"Brain Res."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0210","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1126\/science.287.5455.1053","article-title":"Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice","volume":"287","author":"Mani","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0215","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s002130000483","article-title":"PHNO, a selective dopamine D2 receptor agonist, does not reduce prepulse inhibition of the startle reflex in rats","volume":"151","author":"Martin-Iverson","year":"2000","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0220","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0960-0760(93)90075-8","article-title":"Androgen and progesterone metabolism in the central and peripheral nervous system","volume":"47","author":"Martini","year":"1993","journal-title":"J. Steroid Biochem. Mol. Biol."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0225","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/BF02088095","article-title":"Testosterone and progesterone metabolism in the central nervous system: cellular localization and mechanism of control of the enzymes involved","volume":"16","author":"Martini","year":"1996","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0230","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1002\/mds.23810","article-title":"A preliminary study of finasteride in Tourette syndrome","volume":"26","author":"Muroni","year":"2011","journal-title":"Mov. Disord."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0380","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1176\/appi.ajp.159.3.443","article-title":"Are cognitive impairments associated with sensitivity to stress in schizophrenia? An experience sampling study","volume":"159","author":"Myin-Germeys","year":"2002","journal-title":"Am. J. Psychiatry."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0235","doi-asserted-by":"crossref","first-page":"18676","DOI":"10.1073\/pnas.1008911107","article-title":"Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine","volume":"107","author":"Navarro","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0240","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2174\/138161211795049589","article-title":"Steroid 5\u03b1-reductase as a novel therapeutic target for schizophrenia and other neuropsychiatric disorders","volume":"17","author":"Paba","year":"2011","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0245","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1046\/j.1460-9568.2002.01989.x","article-title":"Strain differences in sigma(1) receptor-mediated behaviours are related to neurosteroid levels","volume":"15","author":"Phan","year":"2002","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0250","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/s00213-006-0311-9","article-title":"In the ventral tegmental area, G-proteins mediate progesterone's actions at dopamine type 1 receptors for lordosis of rats and hamsters","volume":"186","author":"Petralia","year":"2006","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0255","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1007\/BF00589908","article-title":"Interaction between accumbens D1 and D2 receptors regulating rat locomotor activity","volume":"99","author":"Plaznik","year":"1989","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0260","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1523\/JNEUROSCI.21-01-00305.2001","article-title":"Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists","volume":"21","author":"Ralph","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0265","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1124\/jpet.104.074468","article-title":"Dopamine D1 and D2 agonist effects on prepulse inhibition and locomotion: comparison of Sprague\u2013Dawley rats to Swiss-Webster, 129X1\/SvJ, C57BL\/6J, and DBA\/2J mice","volume":"312","author":"Ralph","year":"2005","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0270","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1007\/s00213-006-0511-3","article-title":"Effects of selective dopamine D1-like and D2-like agonists on prepulse inhibition of startle in inbred C3H\/HeJ, SPRET\/EiJ, and CAST\/EiJ mice","volume":"191","author":"Ralph","year":"2007","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0275","doi-asserted-by":"crossref","first-page":"9604","DOI":"10.1523\/JNEUROSCI.22-21-09604.2002","article-title":"Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice","volume":"22","author":"Ralph-Williams","year":"2002","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0280","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1038\/sj.npp.1300017","article-title":"Dopamine D1 rather than D2 receptor agonists disrupt prepulse inhibition of startle in mice","volume":"28","author":"Ralph-Williams","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0290","series-title":"The Dopamine Receptors","first-page":"137","article-title":"Dopamine receptor signaling: intracellular pathways to behavior","author":"Romanelli","year":"2010"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0295","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0074-7742(01)46072-7","article-title":"Neuroactive steroids in neuropsychopharmacology","volume":"46","author":"Rupprecht","year":"2001","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0300","doi-asserted-by":"crossref","first-page":"e43","DOI":"10.1111\/j.1755-5949.2010.00163.x","article-title":"Steroids\u2013dopamine interactions in the pathophysiology and treatment of CNS disorders","volume":"16","author":"S\u00e1nchez","year":"2010","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0305","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1097\/00004583-199407000-00004","article-title":"Tourette's syndrome: what are the influences of gender and comorbid obsessive\u2013compulsive disorder?","volume":"33","author":"Santangelo","year":"1994","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0320","doi-asserted-by":"crossref","first-page":"4325","DOI":"10.1523\/JNEUROSCI.20-11-04325.2000","article-title":"Toward understanding the biology of a complex phenotype: rat strain and substrain differences in the sensorimotor gating-disruptive effects of dopamine agonists","volume":"20","author":"Swerdlow","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0325","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s002130100799","article-title":"Neural circuit regulation of prepulse inhibition of startle in the rat: current knowledge and future challenges","volume":"156","author":"Swerdlow","year":"2001","journal-title":"Psychopharmacology (Berl.)"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0330","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.pbb.2005.08.018","article-title":"Reduced startle gating after D1 blockade: effects of concurrent D2 blockade","volume":"82","author":"Swerdlow","year":"2005","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0335","doi-asserted-by":"crossref","first-page":"8577","DOI":"10.1016\/S0021-9258(18)42482-9","article-title":"Four-amino acid segment in steroid 5 alpha-reductase 1 confers sensitivity to finasteride, a competitive inhibitor","volume":"267","author":"Thigpen","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0340","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.tins.2004.06.006","article-title":"Putting a spin on the dorsal\u2013ventral divide of the striatum","volume":"8","author":"Voorn","year":"2004","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0345","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/BF02244341","article-title":"Intra-accumbens infusion of quinpirole impairs sensorimotor gating of acoustic startle in rats","volume":"113","author":"Wan","year":"1993","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0350","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/0893-133X(95)00133-X","article-title":"Do D1\/D2 interactions regulate prepulse inhibition in rats?","volume":"14","author":"Wan","year":"1996","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0355","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/S0022-3565(24)36678-9","article-title":"The full D1 dopamine receptor agonist SKF-82958 induces neuropeptide mRNA in the normosensitive striatum of rats: regulation of D1\/D2 interactions by muscarinic receptors","volume":"281","author":"Wang","year":"1997","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0360","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1038\/nature01262","article-title":"Initial sequencing and comparative analysis of the mouse genome","volume":"420","author":"Waterston","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0385","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s002130000369","article-title":"Role of dopamine in prepulse inhibition of acoustic startle","volume":"149","author":"Zhang","year":"2000","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.psyneuen.2012.07.014_bib0390","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1046\/j.1365-201x.1999.00579.x","article-title":"Neuroactive steroids: their mechanism of action and their function in the stress response","volume":"167","author":"Zinder","year":"1999","journal-title":"Acta Physiol. Scand."}],"container-title":["Psychoneuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453012002661?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453012002661?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T16:41:47Z","timestamp":1759682507000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306453012002661"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":71,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["S0306453012002661"],"URL":"https:\/\/doi.org\/10.1016\/j.psyneuen.2012.07.014","relation":{},"ISSN":["0306-4530"],"issn-type":[{"value":"0306-4530","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inhibition of 5\u03b1-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL\/6 mice","name":"articletitle","label":"Article Title"},{"value":"Psychoneuroendocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psyneuen.2012.07.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}