{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T18:37:26Z","timestamp":1770489446695,"version":"3.49.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"National Research Foundation of Korea (NRF) grant","award":["NRF-2016R1C1B2006793"],"award-info":[{"award-number":["NRF-2016R1C1B2006793"]}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea Grant","doi-asserted-by":"crossref","award":["NRF-2015M3C7A1028899"],"award-info":[{"award-number":["NRF-2015M3C7A1028899"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychoneuroendocrinology"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.psyneuen.2018.10.024","type":"journal-article","created":{"date-parts":[[2018,10,29]],"date-time":"2018-10-29T13:11:03Z","timestamp":1540818663000},"page":"42-49","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Methylation of the glucocorticoid receptor gene associated with depression in patients with acute coronary syndrome"],"prefix":"10.1016","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4784-4820","authenticated-orcid":false,"given":"Hee-Ju","family":"Kang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyung-Yeol","family":"Bae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Wan","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Il-Seon","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0658-3345","authenticated-orcid":false,"given":"Hye-Ran","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung-Geun","family":"Shin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Joon","family":"Hong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youngkeun","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myung Ho","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Sang","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Min","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.psyneuen.2018.10.024_bib0005","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.psyneuen.2009.09.001","article-title":"Differential expression of glucocorticoid receptor transcripts in major depressive disorder is not epigenetically programmed","volume":"35","author":"Alt","year":"2010","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0010","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Arch. Gen. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0015","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1161\/CIR.0000000000000558","article-title":"Heart disease and stroke statistics-2018 update: a report from the American Heart Association","volume":"137","author":"Benjamin","year":"2018","journal-title":"Circulation"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0020","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jpsychores.2008.03.012","article-title":"Depression is associated with flatter cortisol rhythms in patients with coronary artery disease","volume":"65","author":"Bhattacharyya","year":"2008","journal-title":"J. Psychosom. Res."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0025","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jad.2016.07.038","article-title":"Glucocorticoid receptor DNA methylation, childhood maltreatment and major depression","volume":"206","author":"Bustamante","year":"2016","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0030","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.jocn.2017.05.022","article-title":"A review of DNA methylation in depression","volume":"43","author":"Chen","year":"2017","journal-title":"J. Clin. Neurosci."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0035","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1111\/cdev.12391","article-title":"Individual differences in childhood behavior disorders associated with epigenetic modulation of the cortisol receptor gene","volume":"86","author":"Dadds","year":"2015","journal-title":"Child Dev."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0040","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/nrn2297","article-title":"From inflammation to sickness and depression: when the immune system subjugates the brain","volume":"9","author":"Dantzer","year":"2008","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0045","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3389\/fnins.2014.00369","article-title":"Site-specific methylation changes in the glucocorticoid receptor exon 1F promoter in relation to life adversity: systematic review of contributing factors","volume":"8","author":"Daskalakis","year":"2014","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0050","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nrn1683","article-title":"Stress and the brain: from adaptation to disease","volume":"6","author":"de Kloet","year":"2005","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0055","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1093\/hmg\/ddt531","article-title":"Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites","volume":"23","author":"Florath","year":"2014","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0060","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.cardiores.2004.07.006","article-title":"Does altered glucocorticoid homeostasis increase cardiovascular risk?","volume":"64","author":"Girod","year":"2004","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0065","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1177\/0004867415597304","article-title":"Acute coronary syndrome and depression: a review of shared pathophysiological pathways","volume":"49","author":"Granville Smith","year":"2015","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0070","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0075","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJMra043430","article-title":"Inflammation, atherosclerosis, and coronary artery disease","volume":"352","author":"Hansson","year":"2005","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jad.2016.01.033","article-title":"BDNF val66met polymorphism and depressive disorders in patients with acute coronary syndrome","volume":"194","author":"Kang","year":"2015","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0085","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.pnpbp.2016.09.001","article-title":"Relationship between interleukin-1\u03b2 and depressive disorder after acute coronary syndrome","volume":"72","author":"Kang","year":"2017","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0090","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.pnpbp.2018.02.004","article-title":"Longitudinal associations between glucocorticoid receptor methylation and late-life depression","volume":"84","author":"Kang","year":"2018","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0095","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/0002-9149(67)90023-9","article-title":"Treatment of myocardial infarction in a coronary care unit. A two year experience with 250 patients","volume":"20","author":"Killip","year":"1967","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0100","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4306\/pi.2014.11.1.89","article-title":"Design and methodology for the Korean observational and escitalopram treatment studies of depression in acute coronary syndrome: K-DEPACS and EsDEPACS","volume":"11","author":"Kim","year":"2014","journal-title":"Psychiatry Investig."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0105","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.euroneuro.2015.02.006","article-title":"Serotonergic genes and depressive disorder in acute coronary syndrome: the Koream depression in ACS (K-DEPACS) study","volume":"25","author":"Kim","year":"2015","journal-title":"Eur. Neuropsychopharmacol"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0110","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.psyneuen.2015.08.013","article-title":"BDNF methylation and depressive disorder in acute coronary syndrome: the K-DEPACS and EsDEPACS studies","volume":"62","author":"Kim","year":"2015","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0115","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4088\/JCP.14m09281","article-title":"Escitalopram treatment for depressive patients with acute coronary syndrome: a 24 week double-blind placebo-controlled trial","volume":"76","author":"Kim","year":"2015","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0120","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ijcard.2016.03.044","article-title":"Associations of tumor necrosis factor-\u03b1 levels and polymorphisms with depressin in acute coronary syndrome patients","volume":"212","author":"Kim","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0125","doi-asserted-by":"crossref","first-page":"4902","DOI":"10.1210\/jc.2008-0813","article-title":"Two common haplotypes of the glucocorticoid receptor gene are associated with increased susceptibility to cardiovascular disease in men with familial hypercholesterolemia","volume":"93","author":"Koeijvoets","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0130","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1161\/CIR.0000000000000019","article-title":"Depression as a risk factor for poor prognosis among patients with acute coronary syndrome: systematic review and recommendations: a scientific statement from the American Heart Association","volume":"129","author":"Lichtman","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0135","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s13148-016-0180-y","article-title":"The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation","volume":"8","author":"Li-Tempel","year":"2016","journal-title":"Clin. Epigenetics"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0140","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1017\/S0033291707001377","article-title":"Cardiac history, prior depression and personality predict course of depressive symptoms after myocardial infarction","volume":"39","author":"Martens","year":"2008","journal-title":"Psychol. Med."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0145","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.jpsychires.2014.06.011","article-title":"Association between methylation of the glucocorticoid receptor gene, childhood maltreatment, and clinical severity in borderline personality disorder","volume":"57","author":"Martin-Blanco","year":"2014","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0150","first-page":"506","article-title":"5\u2019-heterogeneity of glucocorticoid receptor messenger RNA is tissue specific: differential regulation of variant transcripts by early-life events","volume":"14","author":"McCormick","year":"2000","journal-title":"Mol. Endocrinol."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0155","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1097\/PSY.0b013e3181842e0c","article-title":"Type-D personality and cortisol in survivors of acute coronary syndrome","volume":"70","author":"Molloy","year":"2008","journal-title":"Psychosom. Med."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0160","doi-asserted-by":"crossref","first-page":"581","DOI":"10.3109\/10253890.2011.602146","article-title":"Epigenetic programming of the HPA axis : early life decides","volume":"14","author":"Murgatroyd","year":"2011","journal-title":"Stress"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0165","doi-asserted-by":"crossref","first-page":"19071","DOI":"10.4238\/2015.December.29.15","article-title":"Glucocorticoid receptor gene (NR3C1) promoter is hypermethylated in Thai females with major depressive disorder","volume":"14","author":"Nantharat","year":"2015","journal-title":"Genet. Mol. Res. GMR."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0170","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1080\/07853890802508934","article-title":"Inflammation and cortisol response in coronary artery disease","volume":"41","author":"Nijm","year":"2009","journal-title":"Ann. Med."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0175","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.bbi.2015.02.002","article-title":"Insufficient glucocorticoid signaling and elevated inflammation in coronary heart disease patients with comorbid depression","volume":"48","author":"Nikkheslat","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0180","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.biopsych.2004.06.003","article-title":"Depression and 24-hour urinary cortisol in medical outpatients with coronary heart disease: the Heart and Soul Study","volume":"56","author":"Otte","year":"2004","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0185","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1016\/j.psyneuen.2009.08.016","article-title":"Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award Winner","volume":"34","author":"Otte","year":"2009","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0190","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1210\/jc.2009-2251","article-title":"Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study","volume":"95","author":"Otte","year":"2010","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0195","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.neubiorev.2015.05.016","article-title":"Glucocorticoid receptor gene (NR3C1) methylation processes as mediators of early adversity in stress related disorders causality: a critical review","volume":"55","author":"Palma-Gudiel","year":"2015","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0200","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/j.tins.2008.06.006","article-title":"The HPA axis in major depression: classical theories and new developments","volume":"31","author":"Pariante","year":"2008","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0205","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.euroneuro.2017.04.001","article-title":"Why are depressed patients inflamed? A reflection on 20 years of research on depression, glucocorticoid resistance and inflammation","volume":"27","author":"Pariante","year":"2017","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0210","doi-asserted-by":"crossref","first-page":"e59","DOI":"10.1038\/tp.2011.60","article-title":"Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of trauma","volume":"1","author":"Perroud","year":"2011","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0215","doi-asserted-by":"crossref","first-page":"334","DOI":"10.3109\/15622975.2013.866693","article-title":"The Tutsi genocide and transgenerational transmission of maternal stress: epigenetics and biology of the HPA axis","volume":"15","author":"Perroud","year":"2014","journal-title":"World J. Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0220","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jpsychires.2017.02.005","article-title":"DNA methylation and expression of stress related genes in PBMC of MDD patients with and without serious suicidal ideation","volume":"89","author":"Roy","year":"2017","journal-title":"J. Psychiatr. Res."},{"issue":"suppl","key":"10.1016\/j.psyneuen.2018.10.024_bib0225","first-page":"22","article-title":"The mini-international neuropsychiatric interview (M.I.N.I): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10","volume":"59","author":"Sheehan","year":"1998","journal-title":"J. Clin. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0230","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1159\/000329846","article-title":"Glucocortiocid sensitivity in mood disorders","volume":"95","author":"Spijker","year":"2012","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0235","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3109\/00048674.2011.570427","article-title":"A topographical map of the causal network of mechanisms underlying the relationship between major depressive disorder and coronary heart disease","volume":"45","author":"Stapelberg","year":"2011","journal-title":"Aust. N. Z. J. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0240","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.jad.2011.06.020","article-title":"Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder","volume":"134","author":"Szczepankiewicz","year":"2011","journal-title":"J. Affect. Disord."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0245","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1111\/j.1399-0004.2012.01843.x","article-title":"The early-life social environment and DNA methylation","volume":"81","author":"Szyf","year":"2012","journal-title":"Clin. Genet."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0250","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/ajmg.b.32150","article-title":"On the outside, looking in: a review and evaluation of the comparability of blood and brain\u2019 -omes\u2019","volume":"162B","author":"Tylee","year":"2013","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0255","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030148","article-title":"Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults","volume":"7","author":"Tyrka","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0260","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1038\/nn1276","article-title":"Epigenetic programming by maternal behavior","volume":"7","author":"Weaver","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0265","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1056\/NEJMra012941","article-title":"Post-traumatic stress disorder","volume":"346","author":"Yehuda","year":"2002","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0270","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3389\/fpsyt.2013.00118","article-title":"Epigenetic Biomarker as predictors and correlates of symptom improvement following psychotherapy in combat veterans with PTSD","volume":"4","author":"Yehuda","year":"2013","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0275","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.atherosclerosis.2015.07.007","article-title":"Promoter methylation of glucocorticoid receptor gene is associated with subclinical atherosclerosis: a monozygotic twin study","volume":"242","author":"Zhao","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.psyneuen.2018.10.024_bib0280","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1002\/ajmg.b.30709","article-title":"Unipolar depression and hippocampal volume: impact of DNA sequence variants of the glucocorticoid receptor gene","volume":"147B","author":"Zobel","year":"2008","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."}],"container-title":["Psychoneuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453018307959?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453018307959?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T17:02:29Z","timestamp":1759683749000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306453018307959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":56,"alternative-id":["S0306453018307959"],"URL":"https:\/\/doi.org\/10.1016\/j.psyneuen.2018.10.024","relation":{},"ISSN":["0306-4530"],"issn-type":[{"value":"0306-4530","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Methylation of the glucocorticoid receptor gene associated with depression in patients with acute coronary syndrome","name":"articletitle","label":"Article Title"},{"value":"Psychoneuroendocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psyneuen.2018.10.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}