{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:38:57Z","timestamp":1792795137758,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81741124"],"award-info":[{"award-number":["81741124"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Psychoneuroendocrinology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1016\/j.psyneuen.2019.02.025","type":"journal-article","created":{"date-parts":[[2019,2,26]],"date-time":"2019-02-26T11:32:22Z","timestamp":1551180742000},"page":"132-142","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":220,"special_numbering":"C","title":["Faecalibacterium prausnitzii (ATCC 27766) has preventive and therapeutic effects on chronic unpredictable mild stress-induced depression-like and anxiety-like behavior in rats"],"prefix":"10.1016","volume":"104","author":[{"given":"Zikai","family":"Hao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.psyneuen.2019.02.025_bib0005","doi-asserted-by":"crossref","first-page":"245","DOI":"10.7888\/juoeh.37.245","article-title":"Chronic psychological stress as a risk factor of osteoporosis","volume":"37","author":"Azuma","year":"2015","journal-title":"J. UOEH"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0010","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1111\/j.1440-1746.2008.05490.x","article-title":"Real-time polymerase chain reaction quantification of specific butyrate-producing bacteria, Desulfovibrio and Enterococcus faecalis in the feces of patients with colorectal cancer","volume":"23","author":"Balamurugan","year":"2010","journal-title":"J. Gastroenterol. Hepatol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0015","first-page":"1","article-title":"Toxicological aspect of some selected medicinal plant samples collected from Djelfa, Algeria region","author":"Begaa","year":"2018","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0020","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.psyneuen.2015.10.001","article-title":"Structural & functional consequences of chronic psychosocial stress on the microbiome & host","volume":"63","author":"Bharwani","year":"2016","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0025","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1007\/s12035-016-9701-0","article-title":"Behavioral and biochemical interaction between nicotine and chronic unpredictable mild stress in mice","volume":"54","author":"Biala","year":"2017","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0030","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0969-2126(99)80023-9","article-title":"The physiological structure of human C-reactive protein and its complex with phosphocholine","volume":"7","author":"D","year":"1999","journal-title":"Structure"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0035","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1016\/j.neuroscience.2010.08.005","article-title":"Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression","volume":"170","author":"Desbonnet","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0040","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1016\/j.psyneuen.2012.03.007","article-title":"Regulation of the stress response by the gut microbiota: implications for psychoneuroendocrinology","volume":"37","author":"Dinan","year":"2012","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0045","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/j.biopsych.2013.05.001","article-title":"Psychobiotics: a novel class of psychotropic","volume":"74","author":"Dinan","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpsychires.2015.02.021","article-title":"Collective unconscious: how gut microbes shape human behavior","volume":"63","author":"Dinan","year":"2015","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0055","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1038\/nn.4030","article-title":"Host microbiota constantly control maturation and function of microglia in the CNS","volume":"18","author":"Erny","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0060","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.brainres.2014.07.050","article-title":"Interactions of innate and adaptive immunity in brain development and function","volume":"1617","author":"Filiano","year":"2015","journal-title":"Brain Res."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0065","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.bbi.2009.05.058","article-title":"Mood and gut feelings","volume":"24","author":"Forsythe","year":"2010","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0070","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/MOG.0b013e3283572ffa","article-title":"On communication between gut microbes and the brain","volume":"28","author":"Forsythe","year":"2012","journal-title":"Curr. Opin. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0075","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.tins.2013.01.005","article-title":"Gut-brain axis: how the microbiome influences anxiety and depression","volume":"36","author":"Foster","year":"2013","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0080","doi-asserted-by":"crossref","first-page":"3611","DOI":"10.1038\/ncomms4611","article-title":"The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism","volume":"5","author":"Frost","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0085","doi-asserted-by":"crossref","first-page":"3049","DOI":"10.2337\/db10-0253","article-title":"Differential adaptation of human gut microbiota to bariatric surgery\u2013induced weight loss links with metabolic and low-grade inflammation markers","volume":"59","author":"Furet","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0090","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1385-299X(00)00056-8","article-title":"Animal models for the study of antidepressant activity","volume":"7","author":"Gambarana","year":"2001","journal-title":"Brain Res. Protoc."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0095","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1136\/gut.39.4.551","article-title":"Intestinal transit in anxiety and depression","volume":"39","author":"Gorard","year":"1996","journal-title":"Gut"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0100","doi-asserted-by":"crossref","first-page":"3643","DOI":"10.1111\/1462-2920.14358","article-title":"The influence of bioregenerative life-support system (BLSS) dietary structure and lifestyle on the gut microbiota: a 105-day ground-based space simulation in Lunar Palace 1","volume":"20","author":"Hao","year":"2018","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0105","doi-asserted-by":"crossref","first-page":"4320","DOI":"10.1128\/AEM.69.7.4320-4324.2003","article-title":"Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces","volume":"69","author":"Hold","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0110","doi-asserted-by":"crossref","first-page":"5201","DOI":"10.3748\/wjg.v22.i22.5201","article-title":"Faecalibacterium prausnitzii supernatant ameliorates dextran sulfate sodium induced colitis by regulating Th17 cell differentiation","volume":"22","author":"Huang","year":"2016","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0115","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.neuroimage.2015.11.018","article-title":"Magnetic resonance spectroscopy reveals oral Lactobacillus promotion of increases in brain GABA, N-acetyl aspartate and glutamate","volume":"125","author":"Janik","year":"2016","journal-title":"Neuroimage"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0120","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.bbi.2015.03.016","article-title":"Altered fecal microbiota composition in patients with major depressive disorder","volume":"48","author":"Jiang","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0125","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jpsychires.2016.07.019","article-title":"Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat","volume":"82","author":"Kelly","year":"2016","journal-title":"J. Psychiatr. Res."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0130","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.bbi.2016.11.018","article-title":"Lost in Translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects","volume":"61","author":"Kelly","year":"2017","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0135","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3389\/fnbeh.2018.00266","article-title":"Oral probiotics ameliorate the behavioral deficits induced by chronic mild stress in mice via the gut microbiota-inflammation Axis","volume":"12","author":"Li","year":"2018","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0140","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/sj.mp.4000586","article-title":"The role of inflammatory mediators in the biology of major depression: central nervous system cytokines modulate the biological substrate of depressive symptoms, regulate stress-responsive systems, and contribute to neurotoxicity and neuroprotection","volume":"4","author":"Licinio","year":"1999","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0145","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.mehy.2004.08.019","article-title":"Major depressive disorder: probiotics may be an adjuvant therapy","volume":"64","author":"Logan","year":"2005","journal-title":"Med. Hypotheses"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0150","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1038\/ismej.2016.176","article-title":"Faecalibacterium prausnitzii: from microbiology to diagnostics and prognostics","volume":"11","author":"Lopezsiles","year":"2017","journal-title":"ISME J."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0155","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2009.01514.x","article-title":"Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine","volume":"294","author":"Louis","year":"2010","journal-title":"FEMS Microbiol. Lett."},{"issue":"Suppl","key":"10.1016\/j.psyneuen.2019.02.025_bib0160","doi-asserted-by":"crossref","first-page":"S120","DOI":"10.1097\/MCG.0b013e31822fecfe","article-title":"Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics","volume":"45","author":"Macfarlane","year":"2011","journal-title":"J. Clin. Gastroenterol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0165","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.3389\/fmicb.2017.01226","article-title":"Functional characterization of novel Faecalibacterium prausnitzii strains isolated from healthy volunteers: a step forward in the use of F. prausnitzii as a next-generation probiotic","volume":"8","author":"Martin","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0170","doi-asserted-by":"crossref","first-page":"15490","DOI":"10.1523\/JNEUROSCI.3299-14.2014","article-title":"Gut microbes and the brain: paradigm shift in neuroscience","volume":"34","author":"Mayer","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0175","first-page":"1","article-title":"Dietary intake and content of some micronutrients and toxic elements in two algerian spices (Coriandrum sativum L. and Cuminum cyminum L.)","author":"Messaoudi","year":"2018","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0180","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1017\/S0007114510004319","article-title":"Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects","volume":"105","author":"Messaoudi","year":"2011","journal-title":"Br. J. Nutr."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0185","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.mib.2013.06.003","article-title":"Faecalibacterium prausnitzii and human intestinal health","volume":"16","author":"Miquel","year":"2013","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0190","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1038\/ismej.2017.24","article-title":"Faecalibacterium prausnitzii treatment improves hepatic health and reduces adipose tissue inflammation in high-fat fed mice","volume":"11","author":"Munukka","year":"2017","journal-title":"ISME J."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0195","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/hup.609","article-title":"Cytokines: abnormalities in major depression and implications for pharmacological treatment","volume":"19","author":"O\u2019Brien","year":"2004","journal-title":"Hum. Psychopharmacol."},{"issue":"448-445","key":"10.1016\/j.psyneuen.2019.02.025_bib0200","article-title":"Probiotic Bifidobacterium longum NCC3001 reduces depression scores and alters brain activity: a pilot study in patients with irritable bowel syndrome","volume":"153","author":"Pinto-Sanchez","year":"2017","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0205","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/266730a0","article-title":"Depression: a new animal model sensitive to antidepressant treatments","volume":"266","author":"PORSOLT","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0210","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.psyneuen.2018.05.020","article-title":"Emerging literature in the microbiota-brain Axis and perinatal mood and anxiety disorders","volume":"95","author":"Rackers","year":"2018","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0215","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1053\/j.gastro.2011.07.043","article-title":"Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome","volume":"141","author":"Rajili\u0107stojanovi\u0107","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0220","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1056\/NEJMra073096","article-title":"Major depressive disorder","volume":"358","author":"RH","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0225","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.psyneuen.2018.10.010","article-title":"Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: a double-blind, randomized, placebo controlled study","volume":"100","author":"Rudzki","year":"2019","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0230","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/j.tins.2016.09.002","article-title":"Psychobiotics and the manipulation of bacteria-gut-Brain signals","volume":"39","author":"Sarkar","year":"2016","journal-title":"Trends Neurosci."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0235","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.neuint.2013.10.006","article-title":"Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl- d -aspartate receptor subunits and d -serine \u2606","volume":"63","author":"Savignac","year":"2013","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0240","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1038\/nprot.2012.044","article-title":"Using the rat forced swim test to assess antidepressant-like activity in rodents","volume":"7","author":"Slattery","year":"2012","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0245","doi-asserted-by":"crossref","first-page":"16731","DOI":"10.1073\/pnas.0804812105","article-title":"Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients","volume":"105","author":"Sokol","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0250","doi-asserted-by":"crossref","first-page":"6438","DOI":"10.1128\/AEM.71.10.6438-6442.2005","article-title":"Fecal microbiota composition and frailty","volume":"71","author":"SP","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0255","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.bbi.2015.04.003","article-title":"A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood","volume":"48","author":"Steenbergen","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0260","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.neuint.2016.06.011","article-title":"The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?","volume":"99","author":"Stilling","year":"2016","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0265","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.neuint.2016.06.011","article-title":"The neuropharmacology of butyrate: The bread and butter of the microbiota-gut-brain axis?","volume":"99","author":"Stilling","year":"2016","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0270","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.bbi.2015.06.025","article-title":"The prebiotics 3\u2032Sialyllactose and 6\u2032Sialyllactose diminish stressor-induced anxiety-like behavior and colonic microbiota alterations: evidence for effects on the gut-brain axis","volume":"50","author":"Tarr","year":"2015","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0275","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.2174\/13816128113199990462","article-title":"Role of monocarboxylate transporters in drug delivery to the brain","volume":"20","author":"Vijay","year":"2014","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0280","article-title":"Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene","volume":"18","author":"Wei","year":"2014","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0285","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ynstr.2016.08.002","article-title":"The chronic mild stress (CMS) model of depression: history, evaluation and usage","volume":"6","author":"Willner","year":"2016","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0290","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S0149-7634(05)80194-0","article-title":"Chronic mild stree-induced anhedonia: a realistic animal model of depression","volume":"16","author":"Willner","year":"1992","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0295","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1038\/sj.npp.1301386","article-title":"Mifepristone repairs region-dependent alteration of synapsin I in hippocampus in rat model of depression","volume":"32","author":"Wu","year":"2007","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.psyneuen.2019.02.025_bib0300","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s12264-010-0323-7","article-title":"Behavioral animal models of depression","volume":"26","author":"Yan","year":"2010","journal-title":"Neurosci. Bull."}],"container-title":["Psychoneuroendocrinology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453018312071?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0306453018312071?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T17:04:42Z","timestamp":1759683882000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0306453018312071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":60,"alternative-id":["S0306453018312071"],"URL":"https:\/\/doi.org\/10.1016\/j.psyneuen.2019.02.025","relation":{},"ISSN":["0306-4530"],"issn-type":[{"value":"0306-4530","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Faecalibacterium prausnitzii (ATCC 27766) has preventive and therapeutic effects on chronic unpredictable mild stress-induced depression-like and anxiety-like behavior in rats","name":"articletitle","label":"Article Title"},{"value":"Psychoneuroendocrinology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.psyneuen.2019.02.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}