{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T15:11:21Z","timestamp":1703430681344},"reference-count":24,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trends in Parasitology"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.pt.2008.07.006","type":"journal-article","created":{"date-parts":[[2008,9,8]],"date-time":"2008-09-08T04:19:31Z","timestamp":1220847571000},"page":"479-481","source":"Crossref","is-referenced-by-count":4,"title":["\u03b1+-thalassaemia and malarial anaemia"],"prefix":"10.1016","volume":"24","author":[{"given":"Ina","family":"Danquah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank P.","family":"Mockenhaupt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pt.2008.07.006_bib1","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/321744a0","article-title":"High frequencies of \u03b1-thalassaemia are the result of natural selection by malaria","volume":"321","author":"Flint","year":"1986","journal-title":"Nature"},{"key":"10.1016\/j.pt.2008.07.006_bib2","doi-asserted-by":"crossref","first-page":"e158","DOI":"10.1371\/journal.pmed.0030158","article-title":"The effect of \u03b1+-thalassaemia on the incidence of malaria and other diseases in children living on the coast of Kenya","volume":"3","author":"Wambua","year":"2006","journal-title":"PLoS Med."},{"key":"10.1016\/j.pt.2008.07.006_bib3","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1182\/blood-2005-01-0313","article-title":"Both heterozygous and homozygous \u03b1+ thalassemias protect against severe and fatal Plasmodium falciparum malaria on the coast of Kenya","volume":"106","author":"Williams","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.pt.2008.07.006_bib4","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1046\/j.1365-2141.1996.d01-1906.x","article-title":"Red blood cell phenotypes in the \u03b1+ thalassaemias from early childhood to maturity","volume":"95","author":"Williams","year":"1996","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.pt.2008.07.006_bib5","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1086\/314959","article-title":"Plasmodium falciparum infection: influence on hemoglobin levels in \u03b1-thalassemia and microcytosis","volume":"180","author":"Mockenhaupt","year":"1999","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.pt.2008.07.006_bib6","doi-asserted-by":"crossref","first-page":"14736","DOI":"10.1073\/pnas.94.26.14736","article-title":"\u03b1+-thalassemia protects children against disease caused by other infections as well as malaria","volume":"94","author":"Allen","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.pt.2008.07.006_bib7","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.1182\/blood-2003-11-4090","article-title":"\u03b1+-thalassemia protects African children from severe malaria","volume":"104","author":"Mockenhaupt","year":"2004","journal-title":"Blood"},{"key":"10.1016\/j.pt.2008.07.006_bib8","doi-asserted-by":"crossref","first-page":"2220","DOI":"10.1001\/jama.297.20.2220","article-title":"Hemoglobin variants and disease manifestations in severe falciparum malaria","volume":"297","author":"May","year":"2007","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.pt.2008.07.006_bib9","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1371\/journal.pmed.0050056","article-title":"Increased microerythrocyte count in homozygous \u03b1+-thalassaemia contributes to protection against severe malarial anaemia","volume":"5","author":"Fowkes","year":"2008","journal-title":"PLoS Med."},{"key":"10.1016\/j.pt.2008.07.006_bib10","doi-asserted-by":"crossref","first-page":"714","DOI":"10.4269\/ajtmh.2008.78.714","article-title":"Reduced risk of uncomplicated malaria episodes in children with \u03b1+-thalassemia in Northeastern Tanzania","volume":"78","author":"Enevold","year":"2008","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2008.07.006_bib11","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/0035-9203(93)90129-E","article-title":"A prospective study of the influence of \u03b1 thalassaemia on morbidity from malaria and immune responses to defined Plasmodium falciparum antigens in Gambian children","volume":"87","author":"Allen","year":"1993","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2008.07.006_bib12","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1073\/pnas.0305306101","article-title":"A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria","volume":"101","author":"Cockburn","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.pt.2008.07.006_bib13","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/0035-9203(87)90253-7","article-title":"The interaction of \u03b1 thalassaemia with malaria","volume":"81","author":"Oppenheimer","year":"1987","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2008.07.006_bib14","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0169-4758(00)01774-9","article-title":"Malaria-related anaemia","volume":"16","author":"Menendez","year":"2000","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.pt.2008.07.006_bib15","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1097\/00062752-200303000-00002","article-title":"Malaria and anemia","volume":"10","author":"Ekvall","year":"2003","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.pt.2008.07.006_bib16","doi-asserted-by":"crossref","first-page":"167","DOI":"10.4269\/ajtmh.2004.71.167","article-title":"Manifestation and outcome of severe malaria in children in northern Ghana","volume":"71","author":"Mockenhaupt","year":"2004","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2008.07.006_bib17","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1046\/j.1365-3156.2003.01092.x","article-title":"Seasonal profiles of malaria infection, anaemia, and bednet use among age groups and communities in northern Ghana","volume":"8","author":"Koram","year":"2003","journal-title":"Trop. Med. Int. Health"},{"key":"10.1016\/j.pt.2008.07.006_bib18","first-page":"581","article-title":"The silent burden of anaemia in Tanzanian children: a community-based study","volume":"81","author":"Schellenberg","year":"2003","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.pt.2008.07.006_bib19","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/S0035-9203(00)90057-9","article-title":"Anaemia in pregnant Ghanaian women: importance of malaria, iron deficiency, and haemoglobinopathies","volume":"94","author":"Mockenhaupt","year":"2000","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2008.07.006_bib20","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1086\/589884","article-title":"\u03b1+-thalassemia protects against anemia associated with asymptomatic malaria: evidence from community-based surveys in Kenya and Tanzania","volume":"198","author":"Veenemans","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.pt.2008.07.006_bib21","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1046\/j.1365-2141.1998.00971.x","article-title":"Alpha thalassaemia is associated with increased soluble transferrin receptor levels","volume":"103","author":"Rees","year":"1998","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.pt.2008.07.006_bib22","doi-asserted-by":"crossref","first-page":"6","DOI":"10.4269\/ajtmh.2001.64.6","article-title":"Short report: increased susceptibility to Plasmodium malariae in pregnant \u03b1+-thalassemic women","volume":"64","author":"Mockenhaupt","year":"2001","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2008.07.006_bib23","doi-asserted-by":"crossref","first-page":"5543","DOI":"10.4049\/jimmunol.179.8.5543","article-title":"Hematin promotes complement alternative pathway-mediated deposition of C3 activation fragments on human erythrocytes: potential implications for the pathogenesis of anemia in malaria","volume":"179","author":"Pawluczkowycz","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.pt.2008.07.006_bib24","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.pt.2005.03.004","article-title":"Complement-regulatory proteins in severe malaria: too little or too much of a good thing?","volume":"21","author":"Stoute","year":"2005","journal-title":"Trends Parasitol."}],"container-title":["Trends in Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492208002043?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492208002043?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T17:38:22Z","timestamp":1557769102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1471492208002043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":24,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S1471492208002043"],"URL":"https:\/\/doi.org\/10.1016\/j.pt.2008.07.006","relation":{},"ISSN":["1471-4922"],"issn-type":[{"value":"1471-4922","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}