{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T01:12:49Z","timestamp":1791162769771,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trends in Parasitology"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1016\/j.pt.2010.08.005","type":"journal-article","created":{"date-parts":[[2010,9,18]],"date-time":"2010-09-18T08:58:04Z","timestamp":1284800284000},"page":"11-16","source":"Crossref","is-referenced-by-count":56,"title":["Consideration of ethics in primaquine therapy against malaria transmission"],"prefix":"10.1016","volume":"27","author":[{"given":"J. Kevin","family":"Baird","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Surjadjaja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pt.2010.08.005_bib0005","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4269\/ajtmh.1958.7.207","article-title":"Infectivity of mosquitoes to Plasmodium vivax following treatment with chloroquine and other antimalarials","volume":"7","author":"Jeffery","year":"1958","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2010.08.005_bib0010","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1128\/AAC.48.4.1329-1334.2004","article-title":"Activities of artesunate and primaquine against asexual and sexual stage parasites in falciparum malaria","volume":"48","author":"Pukrittayakamee","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.pt.2010.08.005_bib0015","doi-asserted-by":"crossref","first-page":"3613","DOI":"10.1182\/blood.V84.11.3613.bloodjournal84113613","article-title":"G6PD deficiency","volume":"84","author":"Beutler","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.pt.2010.08.005_bib0020","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.pt.2006.06.006","article-title":"Mapping the global extent of malaria in 2005","volume":"22","author":"Guerra","year":"2006","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.pt.2010.08.005_bib0025","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/376246a0","article-title":"Natural selection of hemi- and heterozygotes for G6PD deficiency in Africa by resistance to severe malaria","volume":"376","author":"Ruwende","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.pt.2010.08.005_bib0030","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.bcmd.2008.12.005","article-title":"The global prevalence of glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis","volume":"42","author":"Nkhoma","year":"2009","journal-title":"Blood Cells Mol. Dis."},{"key":"10.1016\/j.pt.2010.08.005_bib0035","first-page":"285","article-title":"Primaquine, SN 13272, a new curative agent in vivax malaria; a preliminary report","volume":"9","author":"Edgcomb","year":"1950","journal-title":"J. Nat. Malaria Assoc."},{"key":"10.1016\/j.pt.2010.08.005_bib0040","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1126\/science.124.3220.484-a","article-title":"Enzymatic deficiency in primaquine-sensitive erythrocytes","volume":"124","author":"Carson","year":"1956","journal-title":"Science"},{"key":"10.1016\/j.pt.2010.08.005_bib0045","first-page":"171","article-title":"The hemolytic effect of primaquine. II. The natural course of the hemolytic anemia and the mechanism of its self-limited character","author":"Dern","year":"1954","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.pt.2010.08.005_bib0050","first-page":"621","article-title":"Mitigation of the hemolytic effect of primaquine and enhancement of its action against exoerythrocytic forms of Chesson strain of Plasmodium vivax by intermittent regimens of drug administration","volume":"22","author":"Alving","year":"1960","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.pt.2010.08.005_bib0055","first-page":"80","article-title":"Primaquine sensitivity in Caucasians: hemolytic reactions induced by primaquine in G-6-PD deficient subjects","volume":"70","author":"George","year":"1967","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.pt.2010.08.005_bib0060","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1093\/milmed\/134.9.802","article-title":"Gametocytocidal and sporontocidal effects of primaquine upon two strains of Plasmodium falciparum","volume":"134","author":"Rieckmann","year":"1969","journal-title":"Mil. Med."},{"key":"10.1016\/j.pt.2010.08.005_bib0065","first-page":"625","article-title":"Gametocytocidal and sporontocidal effects of primaquine and of sulfadiazine with pyrimethamine in a chloroquine-resistant strain of Plasmodium falciparum","volume":"38","author":"Rieckmann","year":"1968","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.pt.2010.08.005_bib0070","unstructured":"World Health Organization (2000) The Use of Antimalarial Drugs: Report of a WHO Informal Consultation, 13-17 November 2000 (WHO\/CDS\/RBM\/2001.33), World Health Organization"},{"key":"10.1016\/j.pt.2010.08.005_bib0075","doi-asserted-by":"crossref","first-page":"523","DOI":"10.4269\/ajtmh.2001.65.523","article-title":"Risk factors for gametocyte carriage in Gambian children","volume":"65","author":"von Seidlein","year":"2001","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2010.08.005_bib0080","first-page":"203","article-title":"Mass administration of an antimalarial drug combining 4-aminoquinoline and 8-aminoquinoline in Tanganyika","volume":"27","author":"Clyde","year":"1962","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.pt.2010.08.005_bib0085","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1182\/blood.V25.1.92.92","article-title":"The course of experimentally induced hemolytic anemia in a primaquine-sensitive Caucasian: a case study","volume":"25","author":"Pannacciulli","year":"1965","journal-title":"Blood"},{"key":"10.1016\/j.pt.2010.08.005_bib0090","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/0035-9203(70)90023-4","article-title":"Primaquine-induced haemolysis in G6PD-deficient Burmese","volume":"64","author":"Aung-Tha-Batu","year":"1970","journal-title":"Trans. Roy. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2010.08.005_bib0095","first-page":"349","article-title":"Acute intravascular hemolysis in Vanuatu following a single dose of primaquine in individuals with glucose-6-phosphate dehydrogenase deficiency","volume":"95","author":"Reeve","year":"1992","journal-title":"J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2010.08.005_bib0100","first-page":"134","article-title":"Sensitivity to primaquine in Ceylonese children due to deficiency of erythrocytic glucose-6-phosphate dehydrogenase","volume":"27","author":"Abeyaratne","year":"1968","journal-title":"Ceylon Med. J."},{"key":"10.1016\/j.pt.2010.08.005_bib0105","first-page":"720","article-title":"Effect of primaquine standard dose in the treatment of vivax malaria patients in Thailand","volume":"32","author":"Buchachart","year":"2001","journal-title":"Southeast Asian J. Trop. Med. Public Health"},{"key":"10.1016\/j.pt.2010.08.005_bib0110","first-page":"631","article-title":"The haemolytic effect of a single dose of 45mg of primaquine in G-6-PD deficient Thais","volume":"55","author":"Charoenlarp","year":"1972","journal-title":"J. Med. Assoc. Thai."},{"key":"10.1016\/j.pt.2010.08.005_bib0115","first-page":"391","article-title":"Clinical problems associated with the use of primaquine as a tissue schizontocidal and gametocytocidal drug","volume":"59","author":"Clyde","year":"1981","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.pt.2010.08.005_bib0120","doi-asserted-by":"crossref","first-page":"128","DOI":"10.4269\/ajtmh.1961.10.128","article-title":"Effect of intermittent administration of a combination of amodiaquin and primaquine (Camoprim) on the hematocrit of primaquine-sensitive and non-sensitive children","volume":"10","author":"Hodgkinson","year":"1961","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2010.08.005_bib0125","doi-asserted-by":"crossref","first-page":"605","DOI":"10.4269\/ajtmh.1962.11.605","article-title":"The tolerance to large weekly doses of primaquine and amodiaquine in primaquine-sensitive and non-sensitivity subjects","volume":"11","author":"Cahn","year":"1962","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.pt.2010.08.005_bib0130","doi-asserted-by":"crossref","first-page":"e1023","DOI":"10.1371\/journal.pone.0001023","article-title":"Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulfadoxine-pyrimethamine and artesunate","volume":"2","author":"Shekalaghe","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.pt.2010.08.005_bib0135","doi-asserted-by":"crossref","first-page":"1762","DOI":"10.1128\/AAC.01135-09","article-title":"In Tanzania, hemolysis after a single dose of primaquine co-administered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase deficient individuals","volume":"54","author":"Shekalaghe","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.pt.2010.08.005_bib0140","unstructured":"World Health Organization (1995) Ethics of Medicine and Health (EMRO Technical Papers Series 4, WHO\/EM\/PHP\/1\/E\/G), World Health Organization"},{"key":"10.1016\/j.pt.2010.08.005_bib0145","doi-asserted-by":"crossref","first-page":"e5318","DOI":"10.1371\/journal.pone.0005318","article-title":"Strong gametocytocidal activity of methylene blue-based combination therapy against falciparum malaria: a randomized controlled trial","volume":"4","author":"Coulibaly","year":"2009","journal-title":"PLoS one"},{"key":"10.1016\/j.pt.2010.08.005_bib0150","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1475-2875-8-10","article-title":"Failure of artesunate\u2013mefloquine in treatment of uncomplicated Plasmodium falciparum malaria in southern Cambodia","volume":"8","author":"Rogers","year":"2009","journal-title":"Malaria J."},{"key":"10.1016\/j.pt.2010.08.005_bib0155","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1056\/NEJMoa0808859","article-title":"Artemisinin resistance in Plasmodium falciparum malaria","volume":"361","author":"Dondorp","year":"2009","journal-title":"New Engl. J. Med."},{"key":"10.1016\/j.pt.2010.08.005_bib0160","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1179\/000349803235001886","article-title":"The chemotherapy of rodent malaria, LXI. Drug combinations to impede the selection of resistance, part 4: the potential role of 8-aminoquinolines","volume":"97","author":"Peters","year":"2003","journal-title":"Annals Trop. Med. Parasitol."},{"key":"10.1016\/j.pt.2010.08.005_bib0165","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1186\/1475-2875-7-S1-S8","article-title":"The role of antimalarial drugs in eliminating malaria","volume":"7","author":"White","year":"2008","journal-title":"Malaria J."}],"container-title":["Trends in Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492210001765?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492210001765?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T22:24:57Z","timestamp":1591914297000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1471492210001765"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["S1471492210001765"],"URL":"https:\/\/doi.org\/10.1016\/j.pt.2010.08.005","relation":{},"ISSN":["1471-4922"],"issn-type":[{"value":"1471-4922","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}