{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:53:17Z","timestamp":1792507997865,"version":"4.5.0"},"reference-count":93,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["cell.com","bmn.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Parasitology"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.pt.2014.12.006","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T17:21:13Z","timestamp":1422552073000},"page":"72-81","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":395,"title":["Drug resistance in sea lice: a threat to salmonid aquaculture"],"prefix":"10.1016","volume":"31","author":[{"given":"Stian M\u00f8rch","family":"Aaen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kari Olli","family":"Helgesen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marit J\u00f8rgensen","family":"Bakke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiranpreet","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor Einar","family":"Horsberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pt.2014.12.006_bib0980","series-title":"The State of World Fisheries and Aquaculture 2008. Bi-annual Report","author":"FAO Fisheries and Aquaculture Department, Rome","year":"2009"},{"key":"10.1016\/j.pt.2014.12.006_bib0505","doi-asserted-by":"crossref","first-page":"15103","DOI":"10.1073\/pnas.0905235106","article-title":"Feeding aquaculture in an era of finite resources","volume":"106","author":"Naylor","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.pt.2014.12.006_bib0510","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1002\/ps.482","article-title":"Analysis and management of resistance to chemotherapeutants in salmon lice, Lepeophtheirus salmonis (Copepoda: Caligidae)","volume":"58","author":"Denholm","year":"2002","journal-title":"Pest. Manag. Sci."},{"key":"10.1016\/j.pt.2014.12.006_bib0985","article-title":"How sea lice from salmon farms may cause wild salmonid declines in Europe and North America and be a great threat to fishes elsewhere","author":"Costello","year":"2014","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.pt.2014.12.006_bib0990","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1046\/j.1365-2109.2000.00511.x","article-title":"Laboratory and field investigations of salmon lice Lepeophtheirus salmonis infestation on Atlantic salmon (Salmo salar L.) post-smolts","volume":"31","author":"Finstad","year":"2000","journal-title":"Aquac. Res."},{"key":"10.1016\/j.pt.2014.12.006_bib0995","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/jfd.12061","article-title":"Salmon lice \u2013 impact on wild salmonids and salmon aquaculture","volume":"36","author":"Torrisen","year":"2013","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib1000","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/jfd.12052","article-title":"Impact of early salmon louse, Lepeophtheirus salmonis, infestation and differences in survival and marine growth of sea ranched Atlantic salmon, Salmo salar L., smolts in 1997-2009","volume":"36","author":"Skilbrei","year":"2013","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib1005","first-page":"1","article-title":"Acute and chronic toxicity of two formulations of the pyrethroids pesticide deltamethrin to an amphipod, sand shrimp and lobster larvae","volume":"2876","author":"Fairchild","year":"2010","journal-title":"Can. Tech. Rep. Fish Aquat. Sci."},{"key":"10.1016\/j.pt.2014.12.006_bib1010","doi-asserted-by":"crossref","first-page":"e73539","DOI":"10.1371\/journal.pone.0073539","article-title":"The salmon louse Lepeophtheirus salmonis (Copepoda: Caligidae) life cycle has only two chalimus stages","volume":"8","author":"Hamre","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.pt.2014.12.006_bib0555","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.pt.2006.08.006","article-title":"Ecology of sea lice parasitic on farmed and wild fish","volume":"22","author":"Costello","year":"2006","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.pt.2014.12.006_bib1015","series-title":"WHO Technical Report Series No. 125, 1957. (Insecticides: Seventh Report of the Expert Committee)","author":"WHO","year":"1957"},{"key":"10.1016\/j.pt.2014.12.006_bib0560","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3354\/dao017197","article-title":"Laboratory investigations on the efficacy of hydrogen-peroxide against the salmon louse Lepeophtheirus salmonis and its toxicological and histopathological effects on Atlantic salmon Salmo salar and Chinook salmon Oncorhynchus tshawytscha","volume":"17","author":"Johnson","year":"1993","journal-title":"Dis. Aq. Org."},{"key":"10.1016\/j.pt.2014.12.006_bib0565","first-page":"63","article-title":"Pyrethroids influence on fish","volume":"49","author":"Richterova","year":"2012","journal-title":"Slov. Vet. Res."},{"key":"10.1016\/j.pt.2014.12.006_bib0570","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0044-8486(99)00307-5","article-title":"Tolerance of Atlantic salmon, Salmo salar L., and rainbow trout, Oncorhynchus mykiss (Walbaum), to emamectin benzoate, a new orally administered treatment for sea lice","volume":"184","author":"Roy","year":"2000","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0575","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.20506\/rst.13.4.816","article-title":"Insecticides and acaricides \u2013 resistance and environmental impact","volume":"13","author":"Kunz","year":"1994","journal-title":"Rev. Sci. Tech."},{"key":"10.1016\/j.pt.2014.12.006_bib0580","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1126\/science.231.4743.1255","article-title":"Insecticide resistance \u2013 challenge to pest-management and basic research","volume":"231","author":"Brattsten","year":"1986","journal-title":"Science"},{"key":"10.1016\/j.pt.2014.12.006_bib0585","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.vetpar.2013.06.004","article-title":"Amblyomma cajennense (Acari: Ixodidae) tick populations susceptible or resistant to acaricides in the Mexican tropics","volume":"197","author":"Alonso-Diaz","year":"2013","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.pt.2014.12.006_bib1020","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2011","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.pt.2014.12.006_bib0595","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.aquaculture.2013.09.001","article-title":"Emamectin benzoate resistance and fitness in laboratory reared salmon lice (Lepeophtheirus salmonis)","volume":"416\u2013417","author":"Espedal","year":"2013","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0600","first-page":"99","article-title":"Sensitivity assessment in the progeny of Caligus rogercresseyi to emamectin benzoate","volume":"30","author":"Bravo","year":"2010","journal-title":"Bull. Eur. Assoc. Fish Pathol."},{"key":"10.1016\/j.pt.2014.12.006_bib0605","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/10641260500207109","article-title":"The effects of water temperature, salinity, and currents on the survival and distribution of the infective copepodid stage of sea lice (Lepeophtheirus salmonis) originating on Atlantic salmon farms in the Broughton Archipelago of British Columbia, Canada","volume":"13","author":"Brooks","year":"2005","journal-title":"Rev. Fish. Sci."},{"key":"10.1016\/j.pt.2014.12.006_bib0610","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1111\/j.1365-2109.2011.02900.x","article-title":"Fecundity of the sea louse Caligus rogercresseyi on its native host Eleginops maclovinus captured near salmon farms in southern Chile","volume":"43","author":"Gonzalez","year":"2012","journal-title":"Aquac. Res."},{"key":"10.1016\/j.pt.2014.12.006_bib0615","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1111\/jfd.12223","article-title":"Deltamethrin resistance in the sea louse Caligus rogercresseyi (Boxhall and Bravo) in Chile: bioassay results and usage data for antiparasitic agents with reference to Norwegian conditions","volume":"37","author":"Helgesen","year":"2014","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0620","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/jfd.12053","article-title":"Single dose field bioassay for sensitivity testing in sea lice, Lepeophtheirus salmonis: development of a rapid diagnostic tool","volume":"36","author":"Helgesen","year":"2013","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0625","series-title":"The Surveillance Program for Resistance to Chemotherapeutants in L. salmonis in Norway 2013. Annual Report Oslo","author":"Gr\u00f8ntvedt","year":"2014"},{"key":"10.1016\/j.pt.2014.12.006_bib0630","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1111\/j.1365-2761.2012.01422.x","article-title":"Preliminary success using hydrogen peroxide to treat Atlantic salmon, Salmo salar L., affected with experimentally induced amoebic gill disease (AGD)","volume":"35","author":"Adams","year":"2012","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0635","first-page":"198","article-title":"Molecular cloning and characterization of a novel P-glycoprotein in the salmon louse Lepeophtheirus salmonis","author":"Heumann","year":"2012","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.pt.2014.12.006_bib1025","doi-asserted-by":"crossref","first-page":"e1549","DOI":"10.1371\/journal.pone.0001549","article-title":"The efficacy of emamectin benzoate against infestations of Lepeophtheirus salmonis on farmed Atlantic salmon (Salmo salar L.) in Scotland between 2002 and 2006","volume":"3","author":"Lees","year":"2008","journal-title":"PLoS ONE"},{"key":"10.1016\/j.pt.2014.12.006_bib1030","series-title":"Salmon Lice: an Integrated Approach to Understanding Parasite Abundance and Distribution","first-page":"177","article-title":"Ireland: The development of sea lice management methods","author":"Jackson","year":"2011"},{"key":"10.1016\/j.pt.2014.12.006_bib0650","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/jfd.12018","article-title":"Use of Atlantic salmon, Salmo salar L., farm treatment data and bioassays to assess for resistance of sea lice, Lepeophtheirus salmonis, to emamectin benzoate (SLICE\u00ae) in British Columbia, Canada","volume":"36","author":"Saksida","year":"2013","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0655","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/1471-2156-15-32","article-title":"Pacific and Atlantic Lepeophtheirus salmonis (Kr\u00f8yer, 1838) are allopatric subspecies: Lepeophtheirus salmonis salmonis and. L. salmonis oncorhynchi subspecies novo","volume":"15","author":"Skern Mauritzen","year":"2014","journal-title":"BMC Genet."},{"key":"10.1016\/j.pt.2014.12.006_bib0660","series-title":"Salmon Lice: an Integrated Approach to Understanding Parasite Abundance and Distribution","first-page":"83","article-title":"Sea louse abundance on farmed salmon in the southwestern New Brunswick area of the Bay of Fundy","author":"Chang","year":"2011"},{"key":"10.1016\/j.pt.2014.12.006_bib0665","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3354\/dao02517","article-title":"Effectiveness of emamectin benzoate for treatment of Lepeophtheirus salmonis on farmed Atlantic salmon Salmo salar in the Bay of Fundy","volume":"102","author":"Jones","year":"2012","journal-title":"Can. Dis. Aquat. Organ."},{"key":"10.1016\/j.pt.2014.12.006_bib0670","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/jfd.12022","article-title":"Detection of emamectin benzoate tolerance emergence in different life stages of sea lice, Lepeophtheirus salmonis, on farmed Atlantic salmon, Salmo salar L","volume":"36","author":"Jones","year":"2013","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0675","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.aquaculture.2013.11.027","article-title":"Assessment of sea lice (Lepeophtheirus salmonis) management in New Brunswick, Canada using deltamethrin (AlphaMax\u00ae) through clinical field treatment and laboratory bioassay responses","volume":"422\u2013423","author":"Whyte","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0680","series-title":"Integrated Pest Management Sea Lice Treatments Application Requirements and Systemic Use Workshop. Workshop report St. Andrews NB","article-title":"Industry Update on Pesticide Usage","author":"Beattie","year":"2009"},{"key":"10.1016\/j.pt.2014.12.006_bib0685","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.aquaculture.2008.06.011","article-title":"Sensitivity assessment of Caligus rogercresseyi to emamectin benzoate in Chile","volume":"282","author":"Bravo","year":"2008","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib1035","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1186\/1471-2164-15-937","article-title":"Human-induced evolution caught in action: SNP-array reveals rapid amphi-atlantic spread of pesticide resistance in the salmon ecotoparasite Lepeophtheirus salmonis","volume":"15","author":"Besnier","year":"2014","journal-title":"BMC Genomics"},{"key":"10.1016\/j.pt.2014.12.006_bib1040","series-title":"Bioassays in Arthropods","year":"2007"},{"key":"10.1016\/j.pt.2014.12.006_bib0695","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.aquaculture.2004.11.009","article-title":"Monitoring of the sensitivity of sea lice (Lepeophtheirus salmonis) to pyrethroids in Norway, Ireland and Scotland using bioassays and probit modelling","volume":"244","author":"Sevatdal","year":"2005","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0700","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0044-8486(02)00339-3","article-title":"Determination of reduced sensitivity in sea lice (Lepeophtheirus salmonis) against the pyrethroid deltamethrin using bioassays and probit modelling","volume":"218","author":"Sevatdal","year":"2003","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0705","doi-asserted-by":"crossref","first-page":"119","DOI":"10.3354\/dao01887","article-title":"Optimization and field use of a bioassay to monitor sea lice Lepeophtheirus salmonis sensitivity to emamectin benzoate","volume":"79","author":"Westcott","year":"2008","journal-title":"Dis. Aquat. Organ."},{"key":"10.1016\/j.pt.2014.12.006_bib0710","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.aquaculture.2013.10.041","article-title":"The acute lethality of three anti-sea lice formulations: Alphamax\u00ae, Salmosan\u00ae, and Interox\u00aeParamove\u212250 to lobster and shrimp","volume":"420\u2013421","author":"Burridge","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0715","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/jfd.12055","article-title":"A fixed-dose approach to conducting emamectin benzoate tolerance assessments on field-collected sea lice, Lepeophtheirus salmonis","volume":"36","author":"Whyte","year":"2013","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0720","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1365-2761.2008.00980.x","article-title":"Modelling sea lice dispersion under varying environmental forcing in a Scottish sea loch","volume":"32","author":"Amundrud","year":"2009","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib1045","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1365-2761.2012.01415.x","article-title":"Modelling salmon lice, Lepeophtheirus salmonis, reproduction on farmed Atlantic salmon, Salmo salar L","volume":"36","author":"Stormoen","year":"2012","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0725","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/plankt\/fbl067","article-title":"The copepod parasite (Lepeophtheirus salmonis (Kr\u00f8yer), Caligus elongatus Nordmann) interactions between wild and farmed Atlantic salmon (Salmo salar L.) and wild sea trout (Salmo trutta L.): a mini review","volume":"29","author":"Todd","year":"2006","journal-title":"J. Plank. Res."},{"key":"10.1016\/j.pt.2014.12.006_bib1050","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1365-2761.2008.01003.x","article-title":"Sea lice, Lepeophtheirus salmonis, transfer between wild sympatric adult and juvenile salmon on the north coast of British Columbia, Canada","volume":"32","author":"Gottesfeld","year":"2009","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib1055","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1365-2761.2008.00915.x","article-title":"Spatial and temporal distribution of Lepeophtheirus salmonis (Kr\u00f8yer) larvae in a sea loch containing Atlantic salmon, Salmo salar L., farms on the north-west coast of Scotland","volume":"31","author":"Penston","year":"2008","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0740","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1365-2761.2008.00986.x","article-title":"An assessment of salmon farms and wild salmonids as sources of Lepeophtheirus salmonis (Kr\u00f8yer) copepodids in the water column in Loch Torridon, Scotland","volume":"32","author":"Penston","year":"2009","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib1110","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1098\/rspb.2004.3027","article-title":"Transmission dynamics of parasitic sea lice from farm to wild salmon","volume":"272","author":"Krko\u0161ek","year":"2005","journal-title":"Proc. R. Soc. B"},{"key":"10.1016\/j.pt.2014.12.006_bib0750","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/ps.515","article-title":"Salmon farming: towards an integrated pest management strategy for sea lice","volume":"58","author":"Mordue","year":"2002","journal-title":"Pest. Manag. Sci."},{"key":"10.1016\/j.pt.2014.12.006_bib0760","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1365-2761.2008.01013.x","article-title":"Considerations in developing an integrated pest management programme for control of sea lice on farmed salmon in Pacific Canada","volume":"32","author":"Brooks","year":"2009","journal-title":"J. Fish Dis."},{"key":"10.1016\/j.pt.2014.12.006_bib0765","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/S1984-29612012000100002","article-title":"Acaricide resistance mechanisms in Rhipicephalus (Boophilus) microplus","volume":"21","author":"Guerrero","year":"2012","journal-title":"Braz. J. Vet. Parasitol."},{"key":"10.1016\/j.pt.2014.12.006_bib0770","article-title":"Transcriptomic responses to emamectin benzoate in Pacific and Atlantic Canada salmon lice Lepeophtheirus salmonis with differing levels of drug resistance","author":"Sutherland","year":"2014","journal-title":"Ev. App."},{"key":"10.1016\/j.pt.2014.12.006_bib0775","doi-asserted-by":"crossref","first-page":"866","DOI":"10.2174\/138920112800399077","article-title":"Macrocyclic lactone anthelmintics: Spectrum of activity and mechanism of action","volume":"13","author":"Geary","year":"2012","journal-title":"Curr. Pharm. Biotech."},{"key":"10.1016\/j.pt.2014.12.006_bib1060","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.pestbp.2009.08.005","article-title":"Genetic analysis of abamectin resistance in Tetranychus cinnabarinus","volume":"95","author":"He","year":"2009","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.pt.2014.12.006_bib1065","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1126\/science.1214318","article-title":"Natural variation in a chloride channel subunit confers avermectins resistance in C. elegans","volume":"335","author":"Ghosh","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.pt.2014.12.006_bib1070","doi-asserted-by":"crossref","first-page":"873","DOI":"10.2174\/138920112800399239","article-title":"Resistance to macrocyclic lactones","volume":"13","author":"Wolstenholme","year":"2012","journal-title":"Curr. Pharm. Biotech."},{"key":"10.1016\/j.pt.2014.12.006_bib0795","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1365-2583.2010.01017.x","article-title":"A point mutation in a glutamate-gated chloride channel confers abamectin resistance in the two-spotted spider mite, Tetranychus urticae Koch","volume":"19","author":"Kwon","year":"2010","journal-title":"Insect Mol. Biol."},{"key":"10.1016\/j.pt.2014.12.006_bib0800","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.aquaculture.2012.03.026","article-title":"Role of P-glycoprotein in emamectin benzoate (SLICE\u00ae) resistance in sea lice, Lepeophtheirus salmonis","volume":"344\u2013349","author":"Igboeli","year":"2012","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0805","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1186\/1471-2164-14-408","article-title":"Salmon lice (Lepeophtheirus salmonis) showing varying emamactin benzoate susceptibilities differ in neuronal acetylcholine receptor and GABA-gated chloride channel mRNA expression","volume":"14","author":"Carmichael","year":"2013","journal-title":"BMC Genet."},{"key":"10.1016\/j.pt.2014.12.006_bib0810","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1744-7917.2012.01535.x","article-title":"Chitin synthesis inhibitors: old molecules and new developments","volume":"20","author":"Merzendorfer","year":"2013","journal-title":"Insect Sci."},{"key":"10.1016\/j.pt.2014.12.006_bib0815","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/0048-3575(79)90089-0","article-title":"Mechanisms of resistance to diflubenzuron in the house fly Musca domestica (L)","volume":"12","author":"Pimprikar","year":"1979","journal-title":"Pest. Biochem. Physiol."},{"key":"10.1016\/j.pt.2014.12.006_bib0820","doi-asserted-by":"crossref","first-page":"4407","DOI":"10.1073\/pnas.1200068109","article-title":"Population bulk segregant mapping uncovers resistance mutations and the mode of action of a chitin synthesis inhibitor in arthropods","volume":"109","author":"Van Leeuwen","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.pt.2014.12.006_bib0825","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/BF00118529","article-title":"Studies on the use of hydrogen peroxide as a method for the control of sea lice on Atlantic salmon","volume":"2","author":"Bruno","year":"1994","journal-title":"Aquacult. Int."},{"key":"10.1016\/j.pt.2014.12.006_bib0830","series-title":"Fish Farming Technology","first-page":"233","article-title":"A new method for control of salmon lice","author":"Thomassen","year":"1993"},{"key":"10.1016\/j.pt.2014.12.006_bib1075","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0304-3835(00)00368-2","volume":"156","author":"Fiander","year":"2000","journal-title":"Cancer Lett."},{"key":"10.1016\/j.pt.2014.12.006_bib1080","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0003-9861(92)90071-4","article-title":"Mechanisms of cellular resistance to hydrogen-peroxide, hyperoxia and 4-hydroxy-2-nonenal toxicity \u2013 the significance of increased catalase activity in H2O2-resistant fibroblasts","volume":"292","author":"Spitz","year":"1992","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.pt.2014.12.006_bib0845","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1348-0421.2011.00400.x","article-title":"Microbial resistance in relation to catalase activity to oxidative stress induced by photolysis of hydrogen peroxide","volume":"56","author":"Nakamura","year":"2012","journal-title":"Microbiol. Immunol."},{"key":"10.1016\/j.pt.2014.12.006_bib0850","doi-asserted-by":"crossref","first-page":"3589","DOI":"10.1099\/mic.0.031435-0","article-title":"KatP contributes to OxyR-regulated hydrogen peroxide resistance in Escherichia coli serotype O157:H7","volume":"155","author":"Uhlich","year":"2009","journal-title":"Microbiol. Sgm"},{"key":"10.1016\/j.pt.2014.12.006_bib0855","article-title":"First report of reduced hydrogen peroxide sensitivity in the salmon louse Lepeophtheirus salmonis in Norway","author":"Helgesen","year":"2014","journal-title":"Aquacult. Rep."},{"key":"10.1016\/j.pt.2014.12.006_bib0860","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1126\/science.143.3602.129","article-title":"Cholinesterase inhibition in spider mites susceptible and resistant to organophosphate","volume":"143","author":"Smissaert","year":"1964","journal-title":"Science"},{"key":"10.1016\/j.pt.2014.12.006_bib0865","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0124220","article-title":"Identification of the mechanism behind resistance against the organophosphate azamethiphos in salmon lice (Lepeophtheirus salmonis)","author":"Kaur","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.pt.2014.12.006_bib0870","doi-asserted-by":"crossref","first-page":"16532","DOI":"10.1073\/pnas.1302023110","article-title":"Multiple origins of pyrethroid insecticide resistance across the species complex of a nontarget aquatic crustacean, Hyalella azteca","volume":"110","author":"Weston","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.pt.2014.12.006_bib0875","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1471-2164-8-36","article-title":"Transcription profiling of a recently colonized pyrethroids resistant Anopheles gambiae strain from Ghana","volume":"8","author":"M\u00fcller","year":"2007","journal-title":"BMC Genet."},{"key":"10.1016\/j.pt.2014.12.006_bib1085","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.pt.2010.08.004","article-title":"Pyrethroid resistance in African anopheline mosquitoes: what are the implications for malaria control?","volume":"27","author":"Ranson","year":"2011","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.pt.2014.12.006_bib0885","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1042\/0264-6021:3570065","article-title":"Glutathione S-transferases as antioxidant defence agents confer pyrethroids resistance in Nilaparvata lugens","volume":"357","author":"Vontas","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.pt.2014.12.006_bib1090","doi-asserted-by":"crossref","first-page":"e79443","DOI":"10.1371\/journal.pone.0079443","article-title":"Overexpression of multiple detoxification genes in deltamethrin resistant Laodelphax striatellus (Hemiptera: Delphacidae) in China","volume":"8","author":"Xu","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.pt.2014.12.006_bib0895","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev.en.41.010196.001115","article-title":"Ion channels as targets for insecticides","volume":"41","author":"Bloomquist","year":"1996","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.pt.2014.12.006_bib0900","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1080\/15216540701352042","article-title":"DDT, pyrethrins, pyrethroids and insect sodium channels","volume":"59","author":"Davies","year":"2007","journal-title":"IUBMB Life"},{"key":"10.1016\/j.pt.2014.12.006_bib0905","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.pestbp.2013.02.007","article-title":"Diversity and convergence of sodium channel mutations involved in resistance to pyrethroids","volume":"106","author":"Rinkevich","year":"2013","journal-title":"Pest. Biochem. Physiol."},{"key":"10.1016\/j.pt.2014.12.006_bib0910","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.pestbp.2013.01.001","article-title":"Robust cuticular penetration resistance in the common bed bug (Cimex lectularius L.) correlates with increased steady\u2013state transcript levels of CPR-type cuticle protein genes","volume":"106","author":"Koganemaru","year":"2013","journal-title":"Pest. Biochem. Physiol."},{"key":"10.1016\/j.pt.2014.12.006_bib0915","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1002\/ps.1057","article-title":"Monooxygenase mediated pyrethroid detoxification in sea lice (Lepeophtheirus salmonis)","volume":"61","author":"Sevatdal","year":"2005","journal-title":"Pest. Manag. Sci."},{"key":"10.1016\/j.pt.2014.12.006_bib0920","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.aquaculture.2014.05.018","article-title":"Efficacy of deltamethrin in the control of Caligus rogercresseyi (Boxshall and Bravo) using bath treatment","volume":"432","author":"Bravo","year":"2014","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib1095","series-title":"National Survey of Sea Lice (Lepeophtheirus salmonis Kr\u00f8yer and Caligus elongatus Nordmann) on Fish Farms in Ireland \u2013 2011. Irish Fisheries Bulletin No 40","author":"O\u2019Donohoe","year":"2012"},{"key":"10.1016\/j.pt.2014.12.006_bib1100","series-title":"Terapianbefaling: Behandling mot lakselus i oppdrettsanlegg (2000:02)","author":"Grave","year":"2000"},{"key":"10.1016\/j.pt.2014.12.006_bib1105","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3354\/dao060123","article-title":"Consumption of drugs for sea lice infestations in Norwegian fish farms: methods for assessment of treatment patterns and treatment rate","volume":"60","author":"Grave","year":"2004","journal-title":"Dis. Aquat. Organ."},{"key":"10.1016\/j.pt.2014.12.006_bib0955","series-title":"A Review of the Sea Lice Bath Treatment Dispersion Model Used for Discharge Consenting in Scotland. A Report to the Scottish Aquaculture Research Forum","author":"Corner","year":"2006"},{"key":"10.1016\/j.pt.2014.12.006_bib0960","doi-asserted-by":"crossref","DOI":"10.1111\/are.12460","article-title":"Effects of Caligus rogercresseyi (Boxshall & Bravo 2000) chalimus stage condition (dead, moribund, live) on the estimates of Cypermethrin BETAMAX\u00ae efficacy","author":"Marin","year":"2014","journal-title":"Aquac. Res."},{"key":"10.1016\/j.pt.2014.12.006_bib0965","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1163\/18759866-0690102012","article-title":"The availability and use of chemotherapeutic sea lice control products","volume":"69","author":"Roth","year":"2000","journal-title":"Contrib. Zool."},{"key":"10.1016\/j.pt.2014.12.006_bib0970","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.aquaculture.2010.03.007","article-title":"Effectiveness of hydrogen peroxide in the control of Caligus rogercresseyi in Chile and implications for sea louse management","volume":"303","author":"Bravo","year":"2010","journal-title":"Aquaculture"},{"key":"10.1016\/j.pt.2014.12.006_bib0975","series-title":"Strategic Sea Lice Control Implementation and Impact Within Scottish Tripartite Wo-rking Group Area Management Agreements. Report","author":"Lees","year":"2009"}],"container-title":["Trends in Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492214002098?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492214002098?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,6]],"date-time":"2024-06-06T18:22:08Z","timestamp":1717698128000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1471492214002098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":93,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["S1471492214002098"],"URL":"https:\/\/doi.org\/10.1016\/j.pt.2014.12.006","relation":{},"ISSN":["1471-4922"],"issn-type":[{"value":"1471-4922","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Drug resistance in sea lice: a threat to salmonid aquaculture","name":"articletitle","label":"Article Title"},{"value":"Trends in Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pt.2014.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}