{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T07:38:31Z","timestamp":1761464311089,"version":"build-2065373602"},"reference-count":11,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["bmn.com","cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Parasitology"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.pt.2020.02.002","type":"journal-article","created":{"date-parts":[[2020,3,8]],"date-time":"2020-03-08T10:49:10Z","timestamp":1583664550000},"page":"408-410","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["An Omnivore\u2019s Dilemma: Toxoplasma gondii\u2019s Flexible Metabolic Networks"],"prefix":"10.1016","volume":"36","author":[{"given":"Kami","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pt.2020.02.002_bb0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1005397","article-title":"Bioenergetics-based modeling of Plasmodium falciparum metabolism reveals its essential genes, nutritional requirements, and thermodynamic bottlenecks","volume":"13","author":"Chiappino-Pepe","year":"2017","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.pt.2020.02.002_bb0010","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1004261","article-title":"Metabolic needs and capabilities of Toxoplasma gondii through combined computational and experimental analysis","volume":"11","author":"Tymoshenko","year":"2015","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.pt.2020.02.002_bb0015","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.cell.2017.06.030","article-title":"Functional profiling of a Plasmodium genome reveals an abundance of essential genes","volume":"170","author":"Bushell","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.pt.2020.02.002_bb0020","doi-asserted-by":"crossref","DOI":"10.1126\/science.aap7847","article-title":"Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis","volume":"360","author":"Zhang","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.pt.2020.02.002_bb0025","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/j.cell.2016.08.019","article-title":"A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes","volume":"166","author":"Sidik","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.pt.2020.02.002_bb0030","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1016\/j.cell.2019.10.030","article-title":"Genome-scale identification of essential metabolic processes for targeting the Plasmodium liver stage","volume":"179","author":"Stanway","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.pt.2020.02.002_bb0035","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.chom.2020.01.002","article-title":"Functional and computational genomics reveal unprecedented flexibility in stage-specific Toxoplasma metabolism","volume":"27","author":"Krishnan","year":"2020","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.pt.2020.02.002_bb0040","article-title":"Conditional knockdown of proteins using auxin-inducible degron (AID) fusions in Toxoplasma gondii","volume":"8","author":"Brown","year":"2018","journal-title":"Bio Protoc."},{"key":"10.1016\/j.pt.2020.02.002_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1002392","article-title":"A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor","volume":"7","author":"Sheiner","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.pt.2020.02.002_bb0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000364","article-title":"Intestinal delta-6-desaturase activity determines host range for Toxoplasma sexual reproduction","volume":"17","author":"Martorelli Di Genova","year":"2019","journal-title":"PLoS Biol."},{"key":"10.1016\/j.pt.2020.02.002_bb0055","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.cell.2019.12.013","article-title":"Identification of a master regulator of differentiation in Toxoplasma","volume":"180","author":"Waldman","year":"2020","journal-title":"Cell"}],"container-title":["Trends in Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492220300398?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492220300398?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T07:35:43Z","timestamp":1761464143000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1471492220300398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S1471492220300398"],"URL":"https:\/\/doi.org\/10.1016\/j.pt.2020.02.002","relation":{},"ISSN":["1471-4922"],"issn-type":[{"type":"print","value":"1471-4922"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An Omnivore\u2019s Dilemma: Toxoplasma gondii\u2019s Flexible Metabolic Networks","name":"articletitle","label":"Article Title"},{"value":"Trends in Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pt.2020.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.chom.2020.01.002","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}