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Lett."},{"key":"10.1016\/j.pt.2021.12.005_bb0420","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1146\/annurev.ph.49.030187.001233","article-title":"Erythrocyte membrane elasticity and viscosity","volume":"49","author":"Hochmuth","year":"1987","journal-title":"Annu. Rev. Physiol."},{"key":"10.1016\/j.pt.2021.12.005_bb0425","doi-asserted-by":"crossref","first-page":"6731","DOI":"10.1073\/pnas.0909533107","article-title":"Measurement of red blood cell mechanics during morphological changes","volume":"107","author":"Park","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.pt.2021.12.005_bb0430","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2018.00656","article-title":"Squeezing for life \u2013 properties of red blood cell deformability","volume":"9","author":"Huisjes","year":"2018","journal-title":"Front. Physiol."},{"key":"10.1016\/j.pt.2021.12.005_bb0435","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphys.2019.01613","article-title":"Methods to investigate the deformability of RBC during malaria","volume":"10","author":"Depond","year":"2020","journal-title":"Front. Physiol."},{"key":"10.1016\/j.pt.2021.12.005_bb0440","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4269\/ajtmh.2001.64.1.11425154","article-title":"CR1 density polymorphism on erythrocytes of falciparum malaria patients in Thailand","volume":"64","author":"Nagayasu","year":"2001","journal-title":"Am. J. Trop. Med. 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