{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T19:45:01Z","timestamp":1793994301436,"version":"4.8.0"},"reference-count":10,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T00:00:00Z","timestamp":1651363200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["bmn.com","cell.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Parasitology"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1016\/j.pt.2022.02.006","type":"journal-article","created":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T07:34:52Z","timestamp":1646120092000},"page":"351-352","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["A genetic TRP down the channel to praziquantel resistance"],"prefix":"10.1016","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5475-3583","authenticated-orcid":false,"given":"James A.","family":"Cotton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9167-7532","authenticated-orcid":false,"given":"Stephen R.","family":"Doyle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.pt.2022.02.006_bb0005","series-title":"Weekly Epidemiological Record. Schistosomiasis and Soil-Transmitted Helminthiases: Progress Report, 2020","first-page":"96","author":"World Health Organization","year":"2021"},{"key":"10.1016\/j.pt.2022.02.006_bb0010","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.635869","article-title":"Schistosomiasis morbidity hotspots: roles of the human host, the parasite and their interface in the development of severe morbidity","volume":"12","author":"Mawa","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.pt.2022.02.006_bb0015","doi-asserted-by":"crossref","first-page":"eabj9114","DOI":"10.1126\/scitranslmed.abj9114","article-title":"Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel","volume":"13","author":"Le Clec\u2019h, W.","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.pt.2022.02.006_bb0020","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.pt.2019.11.002","article-title":"The journey to discovering a flatworm target of praziquantel: a long TRP","volume":"36","author":"Park","year":"2020","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.pt.2022.02.006_bb0025","doi-asserted-by":"crossref","first-page":"eabj5832","DOI":"10.1126\/scitranslmed.abj5832","article-title":"Mechanism of praziquantel action at a parasitic flatworm ion channel","volume":"13","author":"Park","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.pt.2022.02.006_bb0030","doi-asserted-by":"crossref","first-page":"4776","DOI":"10.1038\/s41467-021-24958-0","article-title":"Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration","volume":"12","author":"Berger","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.pt.2022.02.006_bb0035","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.pt.2019.01.004","article-title":"Genome-wide approaches to investigate anthelmintic resistance","volume":"35","author":"Doyle","year":"2019","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.pt.2022.02.006_bb0040","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1017\/S0031182020000591","article-title":"Post-genomic progress in helminth parasitology","volume":"147","author":"McVeigh","year":"2020","journal-title":"Parasitology"},{"key":"10.1016\/j.pt.2022.02.006_bb0045","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.pt.2018.08.001","article-title":"Genetic crosses and linkage mapping in schistosome parasites","volume":"34","author":"Anderson","year":"2018","journal-title":"Trends Parasitol."},{"issue":"suppl 1","key":"10.1016\/j.pt.2022.02.006_bb0050","doi-asserted-by":"crossref","first-page":"jeb206482","DOI":"10.1242\/jeb.206482","article-title":"Recent advances in functional genomics for parasitic nematodes of mammals","volume":"223","author":"Castelletto","year":"2020","journal-title":"J. Exp. Biol."}],"container-title":["Trends in Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492222000368?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1471492222000368?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T07:38:14Z","timestamp":1761464294000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1471492222000368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["S1471492222000368"],"URL":"https:\/\/doi.org\/10.1016\/j.pt.2022.02.006","relation":{},"ISSN":["1471-4922"],"issn-type":[{"value":"1471-4922","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A genetic TRP down the channel to praziquantel resistance","name":"articletitle","label":"Article Title"},{"value":"Trends in Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pt.2022.02.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}