{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T20:13:54Z","timestamp":1770840834504,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pulmonary Pharmacology &amp; Therapeutics"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.pupt.2007.05.001","type":"journal-article","created":{"date-parts":[[2007,5,19]],"date-time":"2007-05-19T20:24:31Z","timestamp":1179606271000},"page":"259-263","source":"Crossref","is-referenced-by-count":47,"title":["The expectorant activity of naringenin"],"prefix":"10.1016","volume":"21","author":[{"given":"Bao-qin","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pei-bo","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong-gang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-wei","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Ji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pupt.2007.05.001_bib1","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.jpba.2005.07.031","article-title":"A rapid LC\/MS\/MS quantitation assay for naringin and its two metabolites in rats plasma","volume":"40","author":"Fang","year":"2006","journal-title":"J Pharm Biomed Anal"},{"key":"10.1016\/j.pupt.2007.05.001_bib2","series-title":"Acute respiratory failure in COPD, lung biology in health and disease series","first-page":"391","article-title":"Mucus physiology and pathophysiology: therapeutic aspects","author":"King","year":"1996"},{"key":"10.1016\/j.pupt.2007.05.001_bib3","doi-asserted-by":"crossref","first-page":"L1210","DOI":"10.1152\/ajplung.2000.279.6.L1210","article-title":"Bcl-2 in LPS- and allergen-induced hyperplastic mucous cells in airway epithelia of Brown Norway rats","volume":"279","author":"Tesfaigzi","year":"2000","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.pupt.2007.05.001_bib4","series-title":"The pediatric lung","first-page":"155","article-title":"Mucoactive agents: old and new","author":"Rubin","year":"1997"},{"key":"10.1016\/j.pupt.2007.05.001_bib5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1513\/pats.2306018","article-title":"Relationship of airway epithelial ion transport to chronic bronchitis","volume":"1","author":"Boucher","year":"2004","journal-title":"Proc Am Thorac Soc"},{"key":"10.1016\/j.pupt.2007.05.001_bib6","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0160-5402(84)90033-0","article-title":"Tracheal phenol red secretion, a new method for screening mucosecretolytic compounds","volume":"11","author":"Engler","year":"1984","journal-title":"J Pharmacol Meth"},{"key":"10.1016\/j.pupt.2007.05.001_bib7","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1021\/jm00386a018","article-title":"2-[(3-Pyridinylmethyl)thio]pyrimidine derivatives: new bronchosecretolytic agents","volume":"30","author":"Schickaneder","year":"1987","journal-title":"J Med Chem"},{"key":"10.1016\/j.pupt.2007.05.001_bib8","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1254\/jjp.51.11","article-title":"Effects of anticholinergic bronchodilators on mucociliary transport and airway secretion","volume":"51","author":"Miyata","year":"1989","journal-title":"Jpn J Pharmacol"},{"key":"10.1016\/j.pupt.2007.05.001_bib9","first-page":"693","article-title":"Effect of erdosteine and its metabolites on tracheobronchial mucus production and transport","volume":"14","author":"Scuri","year":"1988","journal-title":"Drug Exp Clin Res"},{"key":"10.1016\/j.pupt.2007.05.001_bib10","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1083\/jcb.7.2.283","article-title":"Incorporation and rate of loss of s35-methionine by adult rat trachea in organ cultures and in living animals","volume":"7","author":"Crocker","year":"1969","journal-title":"J Biophys Biochem Cytol"},{"key":"10.1016\/j.pupt.2007.05.001_bib11","first-page":"1176","article-title":"Induction of mucin secretion from human bronchial tissue and epithelial cells by rhinovirus and lipopolysaccharide","volume":"25","author":"He","year":"2004","journal-title":"Acta pharmacol Sin"},{"key":"10.1016\/j.pupt.2007.05.001_bib12","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0034-5687(01)00214-6","article-title":"Regualation of secretion from mucous and serous cells in the excised ferret trachea","volume":"126","author":"Kishioka","year":"2001","journal-title":"Respir Physiol"},{"key":"10.1016\/j.pupt.2007.05.001_bib13","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1476-5381.1987.tb08992.x","article-title":"The effect of vasoactive intestinal peptide on smooth muscle tone and mucus secretion from the ferret trachea","volume":"91","author":"Webber","year":"1987","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.pupt.2007.05.001_bib14","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1146\/annurev.ph.52.030190.000525","article-title":"The serous cell","volume":"52","author":"Basbaum","year":"1990","journal-title":"Ann Rev Physiol"},{"key":"10.1016\/j.pupt.2007.05.001_bib15","doi-asserted-by":"crossref","first-page":"4434","DOI":"10.1016\/S0021-9258(18)83761-9","article-title":"Lipopolysaccharide interaction with lysozyme. Binding of lipopolysaccharide to lysozyme and inhibition of lysozyme enzymatic activity","volume":"264","author":"Ohno","year":"1989","journal-title":"J Biol Chem"},{"key":"10.1016\/j.pupt.2007.05.001_bib16","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.2042-7158.1994.tb03747.x","article-title":"Ulcer-protecting effects of naringenin on gastric lesions induced by ethanol in rat: role of endogenous prostaglandins","volume":"46","author":"Motilva","year":"1994","journal-title":"J Pharm Pharmacol"}],"container-title":["Pulmonary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094553907000442?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094553907000442?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,13]],"date-time":"2021-08-13T23:56:40Z","timestamp":1628899000000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1094553907000442"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S1094553907000442"],"URL":"https:\/\/doi.org\/10.1016\/j.pupt.2007.05.001","relation":{},"ISSN":["1094-5539"],"issn-type":[{"value":"1094-5539","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}