{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T01:22:44Z","timestamp":1771550564151,"version":"3.50.1"},"reference-count":46,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pulmonary Pharmacology &amp; Therapeutics"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.pupt.2011.01.005","type":"journal-article","created":{"date-parts":[[2011,1,20]],"date-time":"2011-01-20T04:32:38Z","timestamp":1295497958000},"page":"334-338","source":"Crossref","is-referenced-by-count":31,"title":["New concepts in the management of chronic cough"],"prefix":"10.1016","volume":"24","author":[{"given":"Surinder S.","family":"Birring","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.pupt.2011.01.005_bib1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1136\/bmj.38677.559005.55","article-title":"Systematic review and meta-analysis of randomised controlled trials of gastro-oesophageal reflux interventions for chronic cough associated with gastro-oesophageal reflux","volume":"332","author":"Chang","year":"2006","journal-title":"BMJ"},{"key":"10.1016\/j.pupt.2011.01.005_bib2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1745-9974-3-7","article-title":"Obstructive sleep apnoea: a cause of chronic cough","volume":"3","author":"Birring","year":"2007","journal-title":"Cough"},{"key":"10.1016\/j.pupt.2011.01.005_bib3","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1183\/09031936.00110409","article-title":"Chronic cough in patients with sleep-disordered breathing","volume":"35","author":"Chan","year":"2010","journal-title":"Eur Respir J"},{"key":"10.1016\/j.pupt.2011.01.005_bib4","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1745-9974-6-2","article-title":"Chronic cough and obstructive sleep apnea in a community-based pulmonary practice","volume":"6","author":"Sundar","year":"2010","journal-title":"Cough"},{"key":"10.1016\/j.pupt.2011.01.005_bib5","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1183\/09031936.03.00066403","article-title":"Chronic tonsillar enlargement and cough: preliminary evidence of a novel and treatable cause of chronic cough","volume":"23","author":"Birring","year":"2004","journal-title":"Eur Respir J"},{"key":"10.1016\/j.pupt.2011.01.005_bib6","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0165-5876(00)00302-5","article-title":"Lingual tonsillectomy for refractory paroxysmal cough","volume":"53","author":"Lewis","year":"2000","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.pupt.2011.01.005_bib7","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1016\/j.rmed.2009.04.016","article-title":"The importance of basidiomycetous fungi cultured from the sputum of chronic idiopathic cough: a study to determine the existence of recognizable clinical patterns to distinguish CIC from non-CIC","volume":"103","author":"Ogawa","year":"2009","journal-title":"Respir Med"},{"key":"10.1016\/j.pupt.2011.01.005_bib8","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1080\/02770900902846331","article-title":"Efficacy of itraconazole in the treatment of patients with chronic cough whose sputa yield basidiomycetous fungi-fungus-associated chronic cough (FACC)","volume":"46","author":"Ogawa","year":"2009","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.pupt.2011.01.005_bib9","first-page":"S47","article-title":"Chronic cough and esomeprazole: a double-blind, randomised placebo-controlled parellel study","volume":"63","author":"Fathi","year":"2008","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib10","first-page":"S46","article-title":"Relationships between micro-aspiration, gastro-oesophageal reflux and cough in chronic cough subjects","volume":"63","author":"Decalmer","year":"2008","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib11","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1365-2036.2007.03255.x","article-title":"Improved diagnosis of gastro-oesophageal reflux in patients with unexplained chronic cough","volume":"25","author":"Blondeau","year":"2007","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.pupt.2011.01.005_bib12","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1053\/j.gastro.2010.06.050","article-title":"Acoustic cough-reflux associations in chronic cough: potential triggers and mechanisms","volume":"139","author":"Smith","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.pupt.2011.01.005_bib13","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1378\/chest.127.5.1710","article-title":"Chronic idiopathic cough: a discrete clinical entity?","volume":"127","author":"Haque","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.pupt.2011.01.005_bib14","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1136\/thorax.58.12.1066","article-title":"Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis","volume":"58","author":"Birring","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib15","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1378\/chest.127.5.1714","article-title":"Noneosinophilic CD4 lymphocytic airway inflammation in menopausal women with chronic dry cough","volume":"127","author":"Mund","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.pupt.2011.01.005_bib16","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1136\/thorax.58.4.339","article-title":"Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ)","volume":"58","author":"Birring","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib17","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1136\/thorax.57.1.91","article-title":"A\u00a0case of cough, lymphocytic bronchoalveolitis and coeliac disease with improvement following a gluten free diet","volume":"57","author":"Brightling","year":"2002","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib18","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.rmed.2003.10.005","article-title":"Idiopathic chronic cough and organ-specific autoimmune diseases: a case-control study","volume":"98","author":"Birring","year":"2004","journal-title":"Respir Med"},{"key":"10.1016\/j.pupt.2011.01.005_bib19","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1136\/thorax.58.6.533","article-title":"Respiratory symptoms in patients with treated hypothyroidism and inflammatory bowel disease","volume":"58","author":"Birring","year":"2003","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib20","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1136\/thx.2004.034900","article-title":"Airway function and markers of airway inflammation in patients with treated hypothyroidism","volume":"60","author":"Birring","year":"2005","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib21","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1164\/rccm.200203-245OC","article-title":"Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study","volume":"166","author":"Birring","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.pupt.2011.01.005_bib22","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1136\/thorax.56.6.450","article-title":"Sex dependent differences in physiological ageing in the immune system of lower airways in healthy non-smoking volunteers: study of lymphocyte subsets in bronchoalveolar lavage fluid and blood","volume":"56","author":"Mund","year":"2001","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib23","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1378\/chest.127.2.550","article-title":"Cough and glottic-stop reflex sensitivity in health and disease","volume":"127","author":"Prudon","year":"2005","journal-title":"Chest"},{"key":"10.1016\/j.pupt.2011.01.005_bib24","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1164\/rccm.200402-174OC","article-title":"Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough","volume":"170","author":"Groneberg","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.pupt.2011.01.005_bib25","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1097\/01.mlg.0000244377.60334.e3","article-title":"Effectiveness of amitriptyline versus cough suppressants in the treatment of chronic cough resulting from postviral vagal neuropathy","volume":"116","author":"Jeyakumar","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.pupt.2011.01.005_bib26","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/S0140-6736(08)60596-6","article-title":"Management of chronic cough","volume":"371","author":"Pavord","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.pupt.2011.01.005_bib27","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.pupt.2008.10.012","article-title":"Developing antitussives: the ideal clinical trial","volume":"22","author":"Birring","year":"2009","journal-title":"Pulm Pharmacol Ther"},{"issue":"Suppl. 1","key":"10.1016\/j.pupt.2011.01.005_bib28","doi-asserted-by":"crossref","first-page":"S87","DOI":"10.1007\/s00408-009-9185-z","article-title":"The cough hypersensitivity syndrome: a novel paradigm for understanding cough","volume":"188","author":"Morice","year":"2010","journal-title":"Lung"},{"key":"10.1016\/j.pupt.2011.01.005_bib29","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1378\/chest.121.4.1123","article-title":"Evaluation of a cough-specific quality-of-life questionnaire","volume":"121","author":"French","year":"2002","journal-title":"Chest"},{"key":"10.1016\/j.pupt.2011.01.005_bib30","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1111\/j.1398-9995.2005.00743.x","article-title":"A\u00a0new tool to assess and monitor the burden of chronic cough on quality of life: chronic cough impact questionnaire","volume":"60","author":"Baiardini","year":"2005","journal-title":"Allergy"},{"key":"10.1016\/j.pupt.2011.01.005_bib31","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1136\/thx.2009.119776","article-title":"Assessment of gender differences in health status with the Leicester Cough Questionnaire (LCQ)","volume":"64","author":"Birring","year":"2009","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib32","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/978-3-540-79842-2_16","article-title":"Clinical cough IV:what is the minimal important difference for the Leicester Cough Questionnaire?","author":"Raj","year":"2009","journal-title":"Handb Exp Pharmacol"},{"key":"10.1016\/j.pupt.2011.01.005_bib33","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.jclinepi.2009.09.015","article-title":"A\u00a0prospective global measure, the Punum Ladder, provides more valid assessments of quality of life than a retrospective transition measure","volume":"63","author":"Fletcher","year":"2010","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.pupt.2011.01.005_bib34","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0895-4356(94)90036-1","article-title":"Determining a minimal important change in a disease-specific quality of life questionnaire","volume":"47","author":"Juniper","year":"1994","journal-title":"J\u00a0Clin Epidemiol"},{"key":"10.1016\/j.pupt.2011.01.005_bib35","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1164\/rccm.200607-892OC","article-title":"Opiate therapy in chronic cough","volume":"175","author":"Morice","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.pupt.2011.01.005_bib36","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1183\/09031936.00057407","article-title":"The Leicester cough monitor: preliminary validation of an automated cough detection system in chronic cough","volume":"31","author":"Birring","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.pupt.2011.01.005_bib37","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1745-9974-2-8","article-title":"The automatic recognition and counting of cough","volume":"2","author":"Barry","year":"2006","journal-title":"Cough"},{"key":"10.1016\/j.pupt.2011.01.005_bib38","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1745-9974-6-3","article-title":"Validation of an ambulatory cough detection and counting application using voluntary cough under different conditions","volume":"6","author":"Vizel","year":"2010","journal-title":"Cough"},{"key":"10.1016\/j.pupt.2011.01.005_bib39","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1745-9974-2-7","article-title":"Evaluation of a new self-contained, ambulatory, objective cough monitor","volume":"2","author":"Paul","year":"2006","journal-title":"Cough"},{"key":"10.1016\/j.pupt.2011.01.005_bib40","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/j.rmed.2005.09.023","article-title":"Cough frequency, cough sensitivity and health status in patients with chronic cough","volume":"100","author":"Birring","year":"2006","journal-title":"Respir Med"},{"key":"10.1016\/j.pupt.2011.01.005_bib41","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1183\/09031936.00060808","article-title":"The Leiceseter cough monitor","volume":"32","author":"Birring","year":"2008","journal-title":"Eur Respir J"},{"key":"10.1016\/j.pupt.2011.01.005_bib42","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1136\/thx.2010.142711","article-title":"Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial","volume":"65","author":"Yousaf","year":"2010","journal-title":"Thorax"},{"key":"10.1016\/j.pupt.2011.01.005_bib43","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1081\/JAS-120002285","article-title":"Antitussive effect of the leukotriene receptor antagonist zafirlukast in subjects with cough-variant asthma","volume":"39","author":"Dicpinigaitis","year":"2002","journal-title":"J\u00a0Asthma"},{"key":"10.1016\/j.pupt.2011.01.005_bib44","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.jaci.2005.09.055","article-title":"Effect of codeine on objective measurement of cough in chronic obstructive pulmonary disease","volume":"117","author":"Smith","year":"2006","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"Suppl. 1","key":"10.1016\/j.pupt.2011.01.005_bib45","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.1007\/s00408-009-9197-8","article-title":"The efficacy of a NOP1 agonist (SCH486757) in subacute cough","volume":"188","author":"Woodcock","year":"2010","journal-title":"Lung"},{"issue":"12","key":"10.1016\/j.pupt.2011.01.005_bib46","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1136\/thx.2006.064337","article-title":"Efficacy of speech pathology management for chronic cough: a randomised placebo controlled trial of treatment efficacy","volume":"61","author":"Vertigan","year":"2006","journal-title":"Thorax"}],"container-title":["Pulmonary Pharmacology &amp; Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094553911000095?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094553911000095?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T06:23:49Z","timestamp":1543991029000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1094553911000095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S1094553911000095"],"URL":"https:\/\/doi.org\/10.1016\/j.pupt.2011.01.005","relation":{},"ISSN":["1094-5539"],"issn-type":[{"value":"1094-5539","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}