{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:59:29Z","timestamp":1771469969093,"version":"3.50.1"},"reference-count":63,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004410","name":"Scientific and Technological Research Council of Turkey","doi-asserted-by":"publisher","award":["315S289"],"award-info":[{"award-number":["315S289"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005378","name":"Hacettepe University Scientific Research Projects Coordination Unit","doi-asserted-by":"publisher","award":["THD-2016-9383"],"award-info":[{"award-number":["THD-2016-9383"]}],"id":[{"id":"10.13039\/501100005378","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Pulmonary Pharmacology & Therapeutics"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.pupt.2017.06.006","type":"journal-article","created":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T23:15:25Z","timestamp":1498000525000},"page":"170-180","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":24,"special_numbering":"C","title":["Effects of intranasal treatment with slow (GYY4137) and rapid (NaHS) donors of hydrogen sulfide in lipopolysaccharide-induced airway inflammation in mice"],"prefix":"10.1016","volume":"45","author":[{"given":"Yesim","family":"Kaya-Yasar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasemin","family":"Karaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turgut Emrah","family":"Bozkurt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevgen Celik","family":"Onder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inci","family":"Sahin-Erdemli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.pupt.2017.06.006_bib1","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1111\/j.1365-2222.2008.02971.x","article-title":"Pathogenesis of asthma","volume":"38","author":"Holgate","year":"2008","journal-title":"Clin. Exp. Allergy"},{"issue":"6","key":"10.1016\/j.pupt.2017.06.006_bib2","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1164\/ajrccm\/137.6.1441","article-title":"Endotoxin-induced inflammation and injury of the Guinea pig respiratory airways cause bronchial hyporeactivity","volume":"137","author":"Folkerts","year":"1988","journal-title":"Am. Rev. Respir. Dis."},{"issue":"3","key":"10.1016\/j.pupt.2017.06.006_bib3","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/j.jaci.2006.07.012","article-title":"Mechanisms of airway hyperresponsiveness","volume":"118","author":"Cockcroft","year":"2006","journal-title":"J.\u00a0Allergy Clin. Immunol."},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib4","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1183\/09031936.00023608","article-title":"Airway hyperresponsiveness in asthma: lessons from in\u00a0vitro model systems and animal models","volume":"32","author":"Meurs","year":"2008","journal-title":"Eur. Respir. J."},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib5","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1042\/cs1030201","article-title":"New insights into the relationship between airway inflammation and asthma","volume":"103","author":"Wardlaw","year":"2002","journal-title":"Clin. Sci. (Lond)"},{"key":"10.1016\/j.pupt.2017.06.006_bib6","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","article-title":"Hydrogen sulfide and cell signaling","volume":"51","author":"Li","year":"2011","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib7","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1096\/fj.06-6255com","article-title":"Hydrogen sulfide-induces DNA damage and changes in apoptotic gene expression in human lung fibroblast cells","volume":"21","author":"Baskar","year":"2007","journal-title":"FASEB J."},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib8","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.cyto.2008.11.009","article-title":"Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma","volume":"45","author":"Chen","year":"2009","journal-title":"Cytokine"},{"issue":"5","key":"10.1016\/j.pupt.2017.06.006_bib9","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1111\/j.1440-1843.2009.01550.x","article-title":"Serum hydrogen sulfide as a novel marker predicting bacterial involvement in patients with community-acquired lower respiratory tract infections","volume":"14","author":"Chen","year":"2009","journal-title":"Respirology"},{"issue":"9","key":"10.1016\/j.pupt.2017.06.006_bib10","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1113\/expphysiol.2011.057448","article-title":"Hydrogen sulfide and asthma","volume":"96","author":"Wang","year":"2011","journal-title":"Exp. Physiol."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib11","doi-asserted-by":"crossref","first-page":"R51","DOI":"10.1152\/ajpregu.00576.2009","article-title":"Hypoxic pulmonary vasodilation: a paradigm shift with a hydrogen sulfide mechanism","volume":"298","author":"Olson","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib12","doi-asserted-by":"crossref","first-page":"R297","DOI":"10.1152\/ajpregu.00045.2011","article-title":"The therapeutic potential of hydrogen sulfide: separating hype from hope","volume":"301","author":"Olson","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib13","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jaci.2012.10.005","article-title":"Sputum hydrogen sulfide as a novel biomarker of obstructive neutrophilic asthma","volume":"131","author":"Saito","year":"2013","journal-title":"J.\u00a0Allergy Clin. Immunol."},{"issue":"3","key":"10.1016\/j.pupt.2017.06.006_bib14","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.cyto.2010.12.006","article-title":"Involvement of endogenous hydrogen sulfide in cigarette smoke-induced changes in airway responsiveness and inflammation of rat lung","volume":"53","author":"Chen","year":"2011","journal-title":"Cytokine"},{"issue":"4","key":"10.1016\/j.pupt.2017.06.006_bib15","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1254\/jphs.SC0070199","article-title":"Hydrogen sulfide causes relaxation in mouse bronchial smooth muscle","volume":"104","author":"Kubo","year":"2007","journal-title":"J.\u00a0Pharmacol. Sci."},{"issue":"4","key":"10.1016\/j.pupt.2017.06.006_bib16","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.ajpath.2012.12.008","article-title":"The inhibitory role of hydrogen sulfide in airway hyperresponsiveness and inflammation in a mouse model of asthma","volume":"182","author":"Zhang","year":"2013","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.pupt.2017.06.006_bib17","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.phrs.2015.07.032","article-title":"Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation","volume":"100","author":"Roviezzo","year":"2015","journal-title":"Pharmacol. Res."},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib18","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.resp.2012.03.009","article-title":"The message in the air: hydrogen sulfide metabolism in chronic respiratory diseases","volume":"184","author":"Chen","year":"2012","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"10","key":"10.1016\/j.pupt.2017.06.006_bib19","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1089\/ars.2009.2899","article-title":"The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages","volume":"12","author":"Whiteman","year":"2010","journal-title":"Antioxid. Redox Signal"},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib20","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.freeradbiomed.2009.04.014","article-title":"GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat","volume":"47","author":"Li","year":"2009","journal-title":"Free Radic. Biol. Med."},{"issue":"18","key":"10.1016\/j.pupt.2017.06.006_bib21","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1161\/CIRCULATIONAHA.107.753467","article-title":"Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide","volume":"117","author":"Li","year":"2008","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib22","doi-asserted-by":"crossref","first-page":"e32110","DOI":"10.1371\/journal.pone.0032110","article-title":"Intranasal administration of poly(I: C) and LPS in BALB\/c mice induces airway hyperresponsiveness and inflammation via different pathways","volume":"7","author":"Starkhammar","year":"2012","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.pupt.2017.06.006_bib23","doi-asserted-by":"crossref","first-page":"e104114","DOI":"10.1371\/journal.pone.0104114","article-title":"Toll-like receptor ligands LPS and poly (I: C) exacerbate airway hyperresponsiveness in a model of airway allergy in mice, independently of inflammation","volume":"9","author":"Starkhammar","year":"2014","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib24","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1042\/bj2060267","article-title":"Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat","volume":"206","author":"Stipanuk","year":"1982","journal-title":"Biochem. J."},{"issue":"21","key":"10.1016\/j.pupt.2017.06.006_bib25","doi-asserted-by":"crossref","first-page":"6008","DOI":"10.1093\/emboj\/20.21.6008","article-title":"The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel opener","volume":"20","author":"Zhao","year":"2001","journal-title":"EMBO J."},{"issue":"12","key":"10.1016\/j.pupt.2017.06.006_bib26","first-page":"1213","article-title":"Exacerbations of chronic obstructive pulmonary disease","volume":"48","author":"Wedzicha","year":"2003","journal-title":"Respir. Care"},{"key":"10.1016\/j.pupt.2017.06.006_bib27","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1159\/000107056","article-title":"Lipopolysaccharide challenge of humans as a model for chronic obstructive lung disease exacerbations","volume":"14","author":"Kharitonov","year":"2007","journal-title":"Contrib. Microbiol."},{"issue":"4","key":"10.1016\/j.pupt.2017.06.006_bib28","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1002\/eji.200324569","article-title":"Toll-like receptor stimulation induces airway hyper-responsiveness to bradykinin, an effect mediated by JNK and NF-kappa B signaling pathways","volume":"34","author":"Bachar","year":"2004","journal-title":"Eur. J. Immunol."},{"issue":"7","key":"10.1016\/j.pupt.2017.06.006_bib29","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/sj.bjp.0704928","article-title":"An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction","volume":"137","author":"Adner","year":"2002","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.pupt.2017.06.006_bib30","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/1465-9921-8-29","article-title":"IL-1beta induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism","volume":"8","author":"Zhang","year":"2007","journal-title":"Respir. Res."},{"key":"10.1016\/j.pupt.2017.06.006_bib31","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.resp.2016.05.012","article-title":"The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice","volume":"231","author":"Bozkurt","year":"2016","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"4 Pt 1","key":"10.1016\/j.pupt.2017.06.006_bib32","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1164\/ajrccm.153.4.8616573","article-title":"Aerosolized human neutrophil elastase induces airway constriction and hyperresponsiveness with protection by intravenous pretreatment with half-length secretory leukoprotease inhibitor","volume":"153","author":"Suzuki","year":"1996","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib33","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1111\/j.1600-0773.1984.tb01955.x","article-title":"Bronchial anaphylaxis in actively sensitized Sprague Dawley rats: studies on mediators involved","volume":"55","author":"Dahlback","year":"1984","journal-title":"Acta Pharmacol Toxicol (Copenh)"},{"issue":"6","key":"10.1016\/j.pupt.2017.06.006_bib34","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1164\/ajrccm.163.6.2007138","article-title":"Immediate allergic response in small airways","volume":"163","author":"Wohlsen","year":"2001","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib35","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/sj.bjp.0702304","article-title":"Anaphylactic bronchoconstriction in BP2 mice: interactions between serotonin and acetylcholine","volume":"126","author":"Eum","year":"1999","journal-title":"Br. J. Pharmacol."},{"issue":"Pt 13","key":"10.1016\/j.pupt.2017.06.006_bib36","doi-asserted-by":"crossref","first-page":"3355","DOI":"10.1113\/jphysiol.2009.173054","article-title":"Mast cell-cholinergic nerve interaction in mouse airways","volume":"587","author":"Weigand","year":"2009","journal-title":"J.\u00a0Physiol."},{"issue":"7","key":"10.1016\/j.pupt.2017.06.006_bib37","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1038\/sj.bjp.0705720","article-title":"Role of the epithelium and acetylcholine in mediating the contraction to 5-hydroxytryptamine in the mouse isolated trachea","volume":"141","author":"Moffatt","year":"2004","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.pupt.2017.06.006_bib38","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1034\/j.1399-3003.1999.14c26.x","article-title":"The effects of 5-HT on cholinergic contraction in human airways in\u00a0vitro","volume":"14","author":"Dupont","year":"1999","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib39","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.resp.2008.11.012","article-title":"Airway nerves and dyspnea associated with inflammatory airway disease","volume":"167","author":"Undem","year":"2009","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"5","key":"10.1016\/j.pupt.2017.06.006_bib40","first-page":"1059","article-title":"Effect of ozone on bronchial reactivity in atopic and nonatopic subjects","volume":"120","author":"Holtzman","year":"1979","journal-title":"Am. Rev. Respir. Dis."},{"issue":"6","key":"10.1016\/j.pupt.2017.06.006_bib41","first-page":"686","article-title":"Importance of airway inflammation for hyperresponsiveness induced by ozone","volume":"127","author":"Holtzman","year":"1983","journal-title":"Am. Rev. Respir. Dis."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib42","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.resp.2008.05.006","article-title":"Respiratory sensations evoked by activation of bronchopulmonary C-fibers","volume":"167","author":"Lee","year":"2009","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"6","key":"10.1016\/j.pupt.2017.06.006_bib43","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1111\/j.1476-5381.2011.01675.x","article-title":"TNF-alpha-induces airway hyperresponsiveness to cholinergic stimulation in Guinea pig airways","volume":"165","author":"Makwana","year":"2012","journal-title":"Br. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib44","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1124\/jpet.114.221283","article-title":"The effect of phytocannabinoids on airway hyper-responsiveness, airway inflammation, and cough","volume":"353","author":"Makwana","year":"2015","journal-title":"J.\u00a0Pharmacol. Exp. Ther."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib45","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1164\/ajrccm.152.1.7599849","article-title":"5-Hydroxytryptamine facilitates cholinergic bronchoconstriction in human and Guinea pig airways","volume":"152","author":"Takahashi","year":"1995","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.pupt.2017.06.006_bib46","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.resp.2015.11.018","article-title":"Allergic sensitization modifies the pulmonary expression of 5-hydroxytryptamine receptors in Guinea pigs","volume":"223","author":"Cordoba-Rodriguez","year":"2016","journal-title":"Respir. Physiol. Neurobiol."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib47","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.pupt.2013.10.003","article-title":"Investigation of 5-HT4 receptors in bronchial hyperresponsiveness in cigarette smoke-exposed mice","volume":"28","author":"Dupont","year":"2014","journal-title":"Pulm. Pharmacol. Ther."},{"issue":"8","key":"10.1016\/j.pupt.2017.06.006_bib48","doi-asserted-by":"crossref","first-page":"e44170","DOI":"10.1371\/journal.pone.0044170","article-title":"Secondhand smoke exposure causes bronchial hyperreactivity via transcriptionally upregulated endothelin and 5-hydroxytryptamine 2A receptors","volume":"7","author":"Cao","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib49","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1365-2222.2009.03412.x","article-title":"Role of 5-HT2A, 5-HT4 and 5-HT7 receptors in the antigen-induced airway hyperresponsiveness in Guinea-pigs","volume":"40","author":"Segura","year":"2010","journal-title":"Clin. Exp. Allergy"},{"issue":"3","key":"10.1016\/j.pupt.2017.06.006_bib50","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1007\/s11882-008-0043-5","article-title":"Regulation of inflammation by airway smooth muscle","volume":"8","author":"Tliba","year":"2008","journal-title":"Curr. Allergy Asthma Rep."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib51","doi-asserted-by":"crossref","first-page":"L77","DOI":"10.1152\/ajplung.00282.2006","article-title":"CD14 is an essential mediator of LPS-induced airway disease","volume":"293","author":"Brass","year":"2007","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"5","key":"10.1016\/j.pupt.2017.06.006_bib52","doi-asserted-by":"crossref","first-page":"L952","DOI":"10.1152\/ajplung.00420.2001","article-title":"Neutrophils play a critical role in development of LPS-induced airway disease","volume":"283","author":"Savov","year":"2002","journal-title":"Am. J. Physiol. Lung Cell Mol. Physiol."},{"issue":"3","key":"10.1016\/j.pupt.2017.06.006_bib53","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.pupt.2004.01.003","article-title":"The role of neutrophils in LPS-induced changes in pulmonary function in conscious rats","volume":"17","author":"Spond","year":"2004","journal-title":"Pulm. Pharmacol. Ther."},{"issue":"7","key":"10.1016\/j.pupt.2017.06.006_bib54","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1007\/s00011-006-0085-x","article-title":"Airway hyperresponsiveness induced by repetitive intraperitoneal injection of lipopolysacharide and the involvement of inflammation and nitric oxide in Guinea pigs","volume":"55","author":"Jiang","year":"2006","journal-title":"Inflamm. Res."},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib55","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0163-4453(03)00043-4","article-title":"Changes in arterial hydrogen sulfide (H(2)S) content during septic shock and endotoxin shock in rats","volume":"47","author":"Hui","year":"2003","journal-title":"J.\u00a0Infect."},{"issue":"9","key":"10.1016\/j.pupt.2017.06.006_bib56","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1096\/fj.04-3583fje","article-title":"Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse","volume":"19","author":"Li","year":"2005","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib57","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1089\/ars.2011.4005","article-title":"Hydrogen sulfide in the mammalian cardiovascular system","volume":"17","author":"Liu","year":"2012","journal-title":"Antioxid. Redox Signal"},{"issue":"3","key":"10.1016\/j.pupt.2017.06.006_bib58","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/jcmm.12016","article-title":"The complex effects of the slow-releasing hydrogen sulfide donor GYY4137 in a model of acute joint inflammation and in human cartilage cells","volume":"17","author":"Li","year":"2013","journal-title":"J.\u00a0Cell Mol. Med."},{"issue":"2","key":"10.1016\/j.pupt.2017.06.006_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.jvs.2015.10.010","article-title":"Hydrogen sulfide ameliorates acute lung injury induced by infrarenal aortic cross-clamping by inhibiting inflammation and angiopoietin 2 release","volume":"65","author":"Tang","year":"2016","journal-title":"J.\u00a0Vasc. Surg."},{"issue":"6","key":"10.1016\/j.pupt.2017.06.006_bib60","article-title":"GYY4137, a slow-releasing hydrogen sulfide donor, ameliorates renal damage associated with chronic obstructive uropathy","volume":"196","author":"Lin","year":"2016","journal-title":"J.\u00a0Urol."},{"issue":"8","key":"10.1016\/j.pupt.2017.06.006_bib61","doi-asserted-by":"crossref","first-page":"2121","DOI":"10.1089\/ars.2010.3821","article-title":"Hydrogen sulfide ameliorates tobacco smoke-induced oxidative stress and emphysema in mice","volume":"15","author":"Han","year":"2011","journal-title":"Antioxid. Redox Signal"},{"issue":"1\u20133","key":"10.1016\/j.pupt.2017.06.006_bib62","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ejphar.2012.11.025","article-title":"Hydrogen sulfide inhibits oxidative stress in lungs from allergic mice in\u00a0vivo","volume":"698","author":"Benetti","year":"2013","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.pupt.2017.06.006_bib63","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1165\/rcmb.2013-0415OC","article-title":"Inhibitory effect of hydrogen sulfide on ozone-induced airway inflammation, oxidative stress, and bronchial hyperresponsiveness","volume":"52","author":"Zhang","year":"2015","journal-title":"Am. J. Respir. Cell Mol. Biol."}],"container-title":["Pulmonary Pharmacology & Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094553917300470?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1094553917300470?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T07:44:45Z","timestamp":1569483885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1094553917300470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":63,"alternative-id":["S1094553917300470"],"URL":"https:\/\/doi.org\/10.1016\/j.pupt.2017.06.006","relation":{},"ISSN":["1094-5539"],"issn-type":[{"value":"1094-5539","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of intranasal treatment with slow (GYY4137) and rapid (NaHS) donors of hydrogen sulfide in lipopolysaccharide-induced airway inflammation in mice","name":"articletitle","label":"Article Title"},{"value":"Pulmonary Pharmacology & Therapeutics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.pupt.2017.06.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}