{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:31:38Z","timestamp":1790443898541,"version":"4.1.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,11,12]],"date-time":"2018-11-12T00:00:00Z","timestamp":1541980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiology Case Reports"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.radcr.2018.11.007","type":"journal-article","created":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T01:09:46Z","timestamp":1543972186000},"page":"309-314","source":"Crossref","is-referenced-by-count":5,"title":["Late adult-onset adrenomyeloneuropathy evolving with atypical severe frontal lobe syndrome: Importance of neuroimaging"],"prefix":"10.1016","volume":"14","author":[{"given":"Clemente","family":"Dato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guglielmo","family":"Capaldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Terracciano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filomena","family":"Napolitano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"D'Amico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabina","family":"Pappat\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filippo Maria","family":"Santorelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Di Iorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1383-6638","authenticated-orcid":false,"given":"Simone","family":"Sampaolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariarosa AB","family":"Melone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radcr.2018.11.007_bib0001","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/j.bbamcr.2006.07.010","article-title":"X-linked adrenoleukodystrophy: clinical, biochemical and pathogenetic aspects","volume":"1763","author":"Berger","year":"2006","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.radcr.2018.11.007_bib0002","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/ncpneuro0421","article-title":"X-linked adrenoleukodystrophy","volume":"3","author":"Moser","year":"2007","journal-title":"Nat Clin Pract Neurol"},{"key":"10.1016\/j.radcr.2018.11.007_bib0003","doi-asserted-by":"crossref","first-page":"4201","DOI":"10.1096\/fj.08-110866","article-title":"The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters","volume":"22","author":"van Roermund","year":"2008","journal-title":"FASEB J"},{"key":"10.1016\/j.radcr.2018.11.007_bib0004","doi-asserted-by":"crossref","first-page":"19269","DOI":"10.1074\/jbc.M112.445445","article-title":"Impaired very long-chain acyl-CoA beta-oxidation in human X-linked adrenoleukodystrophy fibroblasts is a direct consequence of ABCD1 transporter dysfunction","volume":"288","author":"Wiesinger","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.radcr.2018.11.007_bib0005","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1002\/ajmg.1320260410","article-title":"Phenotype heterogeneity among hemizygotes in a family biochemically screened for adrenoleukodystrophy","volume":"26","author":"Cotrufo","year":"1987","journal-title":"Am J Med Genet"},{"key":"10.1016\/j.radcr.2018.11.007_bib0006","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1093\/brain\/120.8.1485","article-title":"Adrenoleukodystrophy: phenotype, genetics, pathogenesis and therapy","volume":"120","author":"Moser","year":"1997","journal-title":"Brain"},{"key":"10.1016\/j.radcr.2018.11.007_bib0007","series-title":"GeneReviews\u00ae[Internet]","article-title":"X-linked adrenoleukodystrophy","author":"Steinberg","year":"1993"},{"key":"10.1016\/j.radcr.2018.11.007_bib0008","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/brain\/awt361","article-title":"X-linked adrenoleukodystrophy in women: a cross-sectional cohort study","volume":"137","author":"Engelen","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.radcr.2018.11.007_bib0009","first-page":"109","article-title":"The genetic landscape of X-linked adrenoleukodystrophy: inheritance, mutations, modifier genes, and diagnosis","volume":"8","author":"Wiesinger","year":"2015","journal-title":"Appl Clin Genet"},{"key":"10.1016\/j.radcr.2018.11.007_bib0010","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1002\/humu.9303","article-title":"Identification of seven novel mutations in ABCD1 by a DHPLC-based assay in Italian patients with X-linked adrenoleukodystrophy","volume":"25","author":"Montagna","year":"2005","journal-title":"Hum Mutat"},{"key":"10.1016\/j.radcr.2018.11.007_bib0011","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1212\/WNL.0000000000000770","article-title":"Brain fluorodeoxyglucose PET in adrenoleukodystrophy","volume":"83","author":"Salsano","year":"2014","journal-title":"Neurology"},{"key":"10.1016\/j.radcr.2018.11.007_bib0012","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1212\/01.WNL.0000079050.91337.83","article-title":"Analysis of MRI patterns aids prediction of progression in X-linked adrenoleukodystrophy","volume":"61","author":"Loes","year":"2003","journal-title":"Neurology"},{"key":"10.1016\/j.radcr.2018.11.007_bib0013","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.2169\/internalmedicine.51.6899","article-title":"A case of adult-onset adrenoleukodystrophy with frontal lobe dysfunction: a novel point mutation in the ABCD1 gene","volume":"51","author":"Inoue","year":"2012","journal-title":"Intern Med"},{"key":"10.1016\/j.radcr.2018.11.007_bib0014","first-page":"524","article-title":"Adrenoleukodystrophy: imaging with CT, MRI, and PET","volume":"28","author":"Volkow","year":"1987","journal-title":"J Nucl Med"},{"key":"10.1016\/j.radcr.2018.11.007_bib0015","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.parkreldis.2011.06.005","article-title":"Diffuse cortical hypometabolism on (18)F-FDG-PET scan in a case of an adult variant cerebello-brainstem dominant form of ALD manifesting dementia","volume":"18","author":"Kim","year":"2012","journal-title":"Parkinsonism Relat Disord"}],"container-title":["Radiology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1930043318303169?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1930043318303169?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,10]],"date-time":"2019-04-10T11:37:53Z","timestamp":1554896273000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1930043318303169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S1930043318303169"],"URL":"https:\/\/doi.org\/10.1016\/j.radcr.2018.11.007","relation":{},"ISSN":["1930-0433"],"issn-type":[{"value":"1930-0433","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]}}}