{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:31:10Z","timestamp":1780345870283,"version":"3.54.1"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiology Case Reports"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.radcr.2025.09.051","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T06:28:10Z","timestamp":1759559290000},"page":"14-20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Unmasking 5-fluorouracil cardiotoxicity: The clinical utility of dynamic myocardial CT perfusion: A case report"],"prefix":"10.1016","volume":"21","author":[{"given":"Mauricio","family":"Garcia-Cardenas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-0569-7029","authenticated-orcid":false,"given":"Gilberto H.","family":"Acosta-Guti\u00e9rrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nayat","family":"Rivera-Trevi\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8436-354X","authenticated-orcid":false,"given":"Hugo A.","family":"Valencia-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8395-8457","authenticated-orcid":false,"given":"Enrique","family":"Ruiz-Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4820-1325","authenticated-orcid":false,"given":"Nilda","family":"Espinola-Zavaleta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.radcr.2025.09.051_bib0001","first-page":"44","article-title":"Fluoropyrimidine cardiotoxicity: time for a contemporaneous appraisal","volume":"18","author":"Upshaw","year":"2019","journal-title":"Clin Colorectal Cancer"},{"issue":"5","key":"10.1016\/j.radcr.2025.09.051_bib0002","doi-asserted-by":"crossref","first-page":"71","DOI":"10.55729\/2000-9666.1094","article-title":"5-Fluorouracil-related cardiotoxicity with coronary vasospasms","volume":"12","author":"Faheem","year":"2022","journal-title":"J Community Hosp Intern Med Perspect"},{"issue":"5","key":"10.1016\/j.radcr.2025.09.051_bib0003","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.3390\/jcm11051244","article-title":"The role of vasospasm and microcirculatory dysfunction in fluoropyrimidine-induced ischemic heart disease","volume":"11","author":"Fabin","year":"2022","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.radcr.2025.09.051_bib0004","article-title":"5-FU induced cardiotoxicity: case series and review of the literature","volume":"5","author":"Yuan","year":"2019","journal-title":"Cardio-Oncol"},{"issue":"19","key":"10.1016\/j.radcr.2025.09.051_bib0005","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10194426","article-title":"Cardiotoxicity of fluoropyrimidines: epidemiology, mechanisms, diagnosis, and management","volume":"10","author":"Jurczyk","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.radcr.2025.09.051_bib0006","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2022.813883","article-title":"New insights in early detection of anticancer drug-related cardiotoxicity using perfusion and metabolic imaging","volume":"9","author":"Cadour","year":"2022","journal-title":"Front Cardiovasc Med"},{"issue":"1","key":"10.1016\/j.radcr.2025.09.051_bib0007","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jcmg.2021.09.027","article-title":"Paving the way for clinical implementation of dynamic CT perfusion","volume":"15","author":"Pontone","year":"2022","journal-title":"JACC Cardiovasc Imag"},{"issue":"8","key":"10.1016\/j.radcr.2025.09.051_bib0008","doi-asserted-by":"crossref","first-page":"5509","DOI":"10.1007\/s00330-023-09550-y","article-title":"Dynamic myocardial CT perfusion imaging\u2014State of the art","volume":"33","author":"Sliwicka","year":"2023","journal-title":"Eur Radiol"},{"issue":"7","key":"10.1016\/j.radcr.2025.09.051_bib0009","doi-asserted-by":"crossref","first-page":"5096","DOI":"10.1007\/s00330-020-07508-y","article-title":"Prospective comparison of integrated on-site CT-fractional flow reserve and static CT perfusion with coronary CT angiography for detection of flow-limiting coronary stenosis","volume":"31","author":"Guo","year":"2021","journal-title":"Eur Radiol"},{"issue":"2","key":"10.1016\/j.radcr.2025.09.051_bib0010","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s12012-024-09834-9","article-title":"Management of fluoropyrimidine-induced cardiac adverse outcomes following cancer treatment","volume":"24","author":"Rajaeinejad","year":"2024","journal-title":"Cardiovasc Toxicol"},{"key":"10.1016\/j.radcr.2025.09.051_bib0011","doi-asserted-by":"crossref","first-page":"4089","DOI":"10.2147\/DDDT.S469331","article-title":"Cardiotoxicity of anticancer drugs: molecular mechanisms, clinical management and innovative treatment","volume":"18","author":"Gao","year":"2024","journal-title":"Drug Des Devel Ther"},{"issue":"36","key":"10.1016\/j.radcr.2025.09.051_bib0012","article-title":"2024 ESC guidelines for the management of chronic coronary syndromes","volume":"45","author":"Vrints","year":"2024","journal-title":"Eur Heart J [Internet]"},{"issue":"7","key":"10.1016\/j.radcr.2025.09.051_bib0013","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.jcmg.2023.06.001","article-title":"Myocardial CT perfusion imaging in 2023","volume":"16","author":"Nieman","year":"2023","journal-title":"JACC Cardiovasc Imag"},{"issue":"6","key":"10.1016\/j.radcr.2025.09.051_bib0014","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jcct.2016.09.003","article-title":"Diagnostic accuracy of static CT perfusion for the detection of myocardial ischemia. A systematic review and meta-analysis","volume":"10","author":"S\u00f8rgaard","year":"2016","journal-title":"J Cardiovasc Comput Tomogr"},{"issue":"1","key":"10.1016\/j.radcr.2025.09.051_bib0015","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jcmg.2021.07.021","article-title":"Dynamic myocardial perfusion CT for the detection of hemodynamically significant coronary artery disease","volume":"15","author":"Nous","year":"2022","journal-title":"JACC Cardiovasc Imag"},{"issue":"41","key":"10.1016\/j.radcr.2025.09.051_bib0016","doi-asserted-by":"crossref","first-page":"4229","DOI":"10.1093\/eurheartj\/ehac244","article-title":"2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS)","volume":"43","author":"Lyon","year":"2022","journal-title":"Eur Heart J"},{"issue":"1","key":"10.1016\/j.radcr.2025.09.051_bib0017","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-022-17856-y","article-title":"Hypverventilation strain CMR imaging in patients with acute chest pain","volume":"12","author":"Siry","year":"2022","journal-title":"Sci Rep"},{"issue":"10","key":"10.1016\/j.radcr.2025.09.051_bib0018","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1016\/j.jcmg.2021.02.022","article-title":"Hyperventilation\/breath-hold maneuver to detect myocardial ischemia by strain-encoded CMR: diagnostic accuracy of a needle-free stress protocol","volume":"14","author":"Ochs","year":"2021","journal-title":"JACC Cardiovasc Imag"}],"container-title":["Radiology Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1930043325008921?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1930043325008921?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T00:12:37Z","timestamp":1763338357000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1930043325008921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S1930043325008921"],"URL":"https:\/\/doi.org\/10.1016\/j.radcr.2025.09.051","relation":{},"ISSN":["1930-0433"],"issn-type":[{"value":"1930-0433","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Unmasking 5-fluorouracil cardiotoxicity: The clinical utility of dynamic myocardial CT perfusion: A case report","name":"articletitle","label":"Article Title"},{"value":"Radiology Case Reports","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radcr.2025.09.051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Inc. on behalf of University of Washington.","name":"copyright","label":"Copyright"}]}}