{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T18:50:53Z","timestamp":1762541453589},"reference-count":20,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1016\/j.radonc.2005.06.014","type":"journal-article","created":{"date-parts":[[2005,7,13]],"date-time":"2005-07-13T19:40:17Z","timestamp":1121283617000},"page":"5-10","source":"Crossref","is-referenced-by-count":119,"title":["Effects of radiotherapy planning with a dedicated combined PET-CT-simulator of patients with non-small cell lung cancer on dose limiting normal tissues and radiation dose-escalation: A planning study"],"prefix":"10.1016","volume":"77","author":[{"given":"Dirk","family":"De Ruysscher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stofferinus","family":"Wanders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre","family":"Minken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aniek","family":"Lumens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline","family":"Schiffelers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cissie","family":"Stultiens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serve","family":"Halders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liesbeth","family":"Boersma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela van","family":"Baardwijk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Verschueren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique","family":"Hochstenbag","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel","family":"Snoep","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad","family":"Wouters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastiaan","family":"Nijsten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00f8ren M.","family":"Bentzen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marinus van","family":"Kroonenburgh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel","family":"\u00d6llers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Lambin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2005.06.014_bib1","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1148\/radiol.2292021598","article-title":"Non-small cell lung cancer: dual-modality PET\/CT in preoperative staging","volume":"229","author":"Antoch","year":"2003","journal-title":"Radiology"},{"key":"10.1016\/j.radonc.2005.06.014_bib2","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1080\/095530097143860","article-title":"Quantifying the steepness of dose-response curves","volume":"71","author":"Bentzen","year":"1997","journal-title":"Int J Radiat Biol"},{"key":"10.1016\/j.radonc.2005.06.014_bib3","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.ijrobp.2003.10.044","article-title":"Impact of FDG-PET on radiation therapy volume delineation in non-small-cell lung cancer","volume":"59","author":"Bradley","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2005.06.014_bib4","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/S0360-3016(02)04609-6","article-title":"provide the 3D extent of tumor motion for individualized internal target volumes? A phantom study of the limitations of CT and the promise of PET","volume":"55","author":"Caldwell","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2005.06.014_bib5","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0360-3016(03)00346-8","article-title":"Radiation treatment planning with an integrated positron emission and computer tomography (PET\/CT): a feasibility study","volume":"57","author":"Ciernik","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2005.06.014_bib6","first-page":"2499","article-title":"Long-term benefit is observed in a phase III comparison of sequential vs concurrent chemo-radiation for patients with unresected stage III nsclc: RTOG 9410 [Abstract]","author":"Curran","year":"2003","journal-title":"Proc ASCO 9410"},{"key":"10.1016\/j.radonc.2005.06.014_bib7","doi-asserted-by":"crossref","unstructured":"De Ruysscher D, Wanders S, van Haren E, et al. Selective mediastinal node irradiation on basis of the FDG-PET scan in patients with non-small cell lung cancer: results of a prospective clinical study. Int J Radiat Oncol Biol Phys 2005; In Press.","DOI":"10.1016\/j.ijrobp.2004.12.019"},{"key":"10.1016\/j.radonc.2005.06.014_bib8","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1200\/JCO.1999.17.9.2692","article-title":"Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer","volume":"17","author":"Furuse","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2005.06.014_bib9","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1148\/radiol.2263011732","article-title":": Respiration-induced attenuation artifact at PET\/CT: technical considerations","volume":"226","author":"Goerres","year":"2003","journal-title":"Radiology"},{"key":"10.1016\/j.radonc.2005.06.014_bib10","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0360-3016(99)00183-2","article-title":"Clinical dose\u2013volume histogram analysis for pneumonitis after 3D treatment for non-small cell lung cancer (NSCLC)","volume":"45","author":"Graham","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2005.06.014_bib11","unstructured":"ICRU Report 50. Prescribing, Recording, and reporting Photon Beam Therapy. International Commission on Radiation Units and Measurements. 1993."},{"key":"10.1016\/j.radonc.2005.06.014_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0360-3016(98)00196-5","article-title":"Radiation pneumonitis as a function of mean lung dose: an analysis of pooled data from 540 patients","volume":"42","author":"Kwa","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2005.06.014_bib13","doi-asserted-by":"crossref","first-page":"2500","DOI":"10.1056\/NEJMoa022136","article-title":"Staging of non-small-cell lung cancer with integrated positron-emission tomography and computed tomography","volume":"348","author":"Lardinois","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2005.06.014_bib14","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0169-5002(99)00019-7","article-title":"Estimation of tumor control probability model parameters from 3-D dose distributions of non-small cell lung cancer patients","volume":"24","author":"Martel","year":"1999","journal-title":"Lung Cancer"},{"key":"10.1016\/j.radonc.2005.06.014_bib15","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/S0022-5223(19)39559-5","article-title":"Lymph node mapping and curability at various levels of metastasis in resected lung cancer","volume":"76","author":"Naruke","year":"1978","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.radonc.2005.06.014_bib16","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0167-8140(99)00087-0","article-title":"Continuous, hyperfractionated, accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: mature data from the randomised multi-center trial","volume":"52","author":"Saunders","year":"1999","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2005.06.014_bib17","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1378\/chest.117.2.358","article-title":"Final results of phase III trial in regionally advanced unresectable non-small cell lung cancer: Radiation Therapy Oncology Group Eastern Cooperative Oncology Group, and Southwest Oncology Group","volume":"117","author":"Sause","year":"2000","journal-title":"Chest"},{"key":"10.1016\/j.radonc.2005.06.014_bib18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.radonc.2003.09.007","article-title":"Literature-based recommendations for treatment planning and execution for high-precision radiotherapy in lung cancer","volume":"71","author":"Senan","year":"2004","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2005.06.014_bib19","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.ijrobp.2004.06.205","article-title":"Increased therapeutic ratio by 18FDG-PET-CT planning in patients with clinical CT stage N2\/N3 M0 non-small cell lung cancer (NSCLC): A modelling study","volume":"61","author":"van der Wel","year":"2005","journal-title":"Int J Radiation Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2005.06.014_bib20","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1007\/s002590050327","article-title":"FDG-PET scan in potentially operable non-small cell lung cancer: Do anatometabolic PET-CT fusion images improve the localisation of regional lymph node metastases?","volume":"25","author":"Vansteenkiste","year":"1998","journal-title":"Eur J Nucl Med"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016781400500215X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016781400500215X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T06:57:04Z","timestamp":1586329024000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016781400500215X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S016781400500215X"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2005.06.014","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]}}}