{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T17:51:13Z","timestamp":1773856273332,"version":"3.50.1"},"reference-count":17,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.radonc.2010.12.013","type":"journal-article","created":{"date-parts":[[2011,2,7]],"date-time":"2011-02-07T09:11:17Z","timestamp":1297069877000},"page":"223-226","source":"Crossref","is-referenced-by-count":20,"title":["Parotid gland as a risk organ in whole brain radiotherapy"],"prefix":"10.1016","volume":"98","author":[{"given":"O Kyu","family":"Noh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mison","family":"Chun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Soo","family":"Nam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyunsoo","family":"Jang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunmi","family":"Jo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young-Taek","family":"Oh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Chul","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2010.12.013_b0005","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1056\/NEJM199908123410703","article-title":"Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission","volume":"341","author":"Auperin","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2010.12.013_b0010","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.ijrobp.2004.12.076","article-title":"Dose\u2013volume modeling of salivary function in patients with head-and-neck cancer receiving radiotherapy","volume":"62","author":"Blanco","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2010.12.013_b0015","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.radonc.2004.02.019","article-title":"Survival following whole brain radiation treatment for cerebral metastases: an audit of 474 patients","volume":"71","author":"Broadbent","year":"2004","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2010.12.013_b0020","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0167-8140(01)00427-3","article-title":"Parotid and submandibular\/sublingual salivary flow during high dose radiotherapy","volume":"61","author":"Burlage","year":"2001","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2010.12.013_b0025","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0360-3016(91)90172-Z","article-title":"Fitting of normal tissue tolerance data to an analytic function","volume":"21","author":"Burman","year":"1991","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2010.12.013_b0030","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0360-3016(92)90567-2","article-title":"The role of radiation therapy in the treatment of brain metastases","volume":"23","author":"Coia","year":"1992","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2010.12.013_b0035","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/j.ijrobp.2009.06.090","article-title":"Radiotherapy dose\u2013volume effects on salivary gland function","volume":"76","author":"Deasy","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2010.12.013_b0040","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0360-3016(99)00247-3","article-title":"Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer","volume":"45","author":"Eisbruch","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2010.12.013_b0045","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s11060-009-0060-9","article-title":"The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline","volume":"96","author":"Gaspar","year":"2010","journal-title":"J Neuro-Oncol"},{"key":"10.1016\/j.radonc.2010.12.013_b0050","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.ijrobp.2004.12.035","article-title":"Volume effects and region-dependent radiosensitivity of the parotid gland","volume":"62","author":"Konings","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2010.12.013_b0055","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.2307\/3583506","article-title":"Complication probability as assessed from dose\u2013volume histograms","volume":"8","author":"Lyman","year":"1985","journal-title":"Radiat Res Suppl"},{"key":"10.1016\/j.radonc.2010.12.013_b0060","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1056\/NEJMra052603","article-title":"Treatment of acute lymphoblastic leukemia","volume":"354","author":"Pui","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2010.12.013_b0065","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/S0360-3016(01)01717-5","article-title":"Quantitative dose\u2013volume response analysis of changes in parotid gland function after radiotherapy in the head-and-neck region","volume":"51","author":"Roesink","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2010.12.013_b0070","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0167-8140(00)00154-7","article-title":"CT-based parotid gland location: implications for preservation of parotid function","volume":"55","author":"Roesink","year":"2000","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2010.12.013_b0075","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.radonc.2006.02.017","article-title":"Sparing of the submandibular glands by intensity modulated radiotherapy in the treatment of head and neck cancer","volume":"78","author":"Saarilahti","year":"2006","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2010.12.013_b0080","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1056\/NEJMoa071780","article-title":"Prophylactic cranial irradiation in extensive small-cell lung cancer","volume":"357","author":"Slotman","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2010.12.013_b0085","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.ijrobp.2009.07.1734","article-title":"A novel dose constraint to reduce xerostomia in head-and-neck cancer patients treated with intensity-modulated radiotherapy","volume":"77","author":"Strigari","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814011000077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814011000077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,5]],"date-time":"2018-12-05T01:22:36Z","timestamp":1543972956000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814011000077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0167814011000077"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2010.12.013","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}