{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T21:01:07Z","timestamp":1791234067863,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2011,12]]},"DOI":"10.1016\/j.radonc.2011.05.040","type":"journal-article","created":{"date-parts":[[2011,6,20]],"date-time":"2011-06-20T22:22:41Z","timestamp":1308608561000},"page":"356-361","source":"Crossref","is-referenced-by-count":46,"title":["Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity"],"prefix":"10.1016","volume":"101","author":[{"given":"James D.","family":"Murphy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen M.","family":"Chisholm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan E.","family":"Daly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen A.","family":"Wiegner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Truong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Iagaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter G.","family":"Maxim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Billy W.","family":"Loo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward E.","family":"Graves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quynh-Thu","family":"Le","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2011.05.040_b0005","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1200\/JCO.20.5.1398","article-title":"Standardized uptake value of 2-[(18)F] fluoro-2-deoxy-d-glucose in predicting outcome in head and neck carcinomas treated by radiotherapy with or without chemotherapy","volume":"20","author":"Allal","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0010","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.ijrobp.2003.12.039","article-title":"Prediction of outcome in head-and-neck cancer patients using the standardized uptake value of 2-[18F]fluoro-2-deoxy-d-glucose","volume":"59","author":"Allal","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0015","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/j.ijrobp.2004.06.254","article-title":"Defining a radiotherapy target with positron emission tomography","volume":"60","author":"Black","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0020","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.mibio.2004.04.006","article-title":"Positron emission tomography\/computed tomography \u2013 imaging protocols, artifacts, and pitfalls","volume":"6","author":"Bockisch","year":"2004","journal-title":"Mol Imaging Biol"},{"key":"10.1016\/j.radonc.2011.05.040_b0025","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/01.rlu.0000191786.35378.47","article-title":"Normal uptake of F-18 FDG in the sublingual gland","volume":"31","author":"Bogsrud","year":"2006","journal-title":"Clin Nucl Med"},{"key":"10.1016\/j.radonc.2011.05.040_b0030","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.1600-0714.1989.tb01339.x","article-title":"New malignancy grading is a better prognostic indicator than Broders\u2019 grading in oral squamous cell carcinomas","volume":"18","author":"Bryne","year":"1989","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.radonc.2011.05.040_b0035","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.ijrobp.2007.10.055","article-title":"Correlation of positron emission tomography standard uptake value and pathologic specimen size in cancer of the head and neck","volume":"71","author":"Burri","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0040","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1365-2559.2010.03616.x","article-title":"Invasive pattern grading score designed as an independent prognostic indicator in oral squamous cell carcinoma","volume":"57","author":"Chang","year":"2010","journal-title":"Histopathology"},{"key":"10.1016\/j.radonc.2011.05.040_b0045","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.radonc.2008.11.014","article-title":"The limitation of PET imaging for biological adaptive-IMRT assessed in animal models","volume":"91","author":"Christian","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0050","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/S0360-3016(03)00346-8","article-title":"Radiation treatment planning with an integrated positron emission and computer tomography (PET\/CT): a feasibility study","volume":"57","author":"Ciernik","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0055","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1148\/radiol.2331030660","article-title":"Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen","volume":"233","author":"Daisne","year":"2004","journal-title":"Radiology"},{"key":"10.1016\/j.radonc.2011.05.040_b0060","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0167-8140(03)00270-6","article-title":"Tri-dimensional automatic segmentation of PET volumes based on measured source-to-background ratios: influence of reconstruction algorithms","volume":"69","author":"Daisne","year":"2003","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0065","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1007\/s00259-006-0363-4","article-title":"A gradient-based method for segmenting FDG-PET images: methodology and validation","volume":"34","author":"Geets","year":"2007","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"10.1016\/j.radonc.2011.05.040_b0070","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.radonc.2007.05.010","article-title":"Adaptive biological image-guided IMRT with anatomic and functional imaging in pharyngo-laryngeal tumors: impact on target volume delineation and dose distribution using helical tomotherapy","volume":"85","author":"Geets","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0075","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1177\/153303460700600207","article-title":"RT_Image: an open-source tool for investigating PET in radiation oncology","volume":"6","author":"Graves","year":"2007","journal-title":"Technol Cancer Res Treat"},{"key":"10.1016\/j.radonc.2011.05.040_b0080","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.radonc.2009.09.010","article-title":"Comparison between CT- and FDG-PET-defined target volumes for radiotherapy planning in head-and-neck cancers","volume":"93","author":"Henriques de Figueiredo","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0085","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1016\/j.ijrobp.2004.05.037","article-title":"Hybrid PET\u2013CT simulation for radiation treatment planning in head-and-neck cancers: a brief technical report","volume":"60","author":"Heron","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0090","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.joms.2007.08.006","article-title":"Quantitative analysis of invasive front in tongue cancer using ultrasonography","volume":"67","author":"Kaneoya","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.radonc.2011.05.040_b0095","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/j.ijrobp.2008.10.060","article-title":"Metabolic tumor volume predicts for recurrence and death in head-and-neck cancer","volume":"74","author":"La","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0100","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1200\/JCO.2009.24.6298","article-title":"Positron emission tomography with [18F]fluorodeoxyglucose improves staging and patient management in patients with head and neck squamous cell carcinoma: a multicenter prospective study","volume":"28","author":"Lonneux","year":"2010","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0105","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.ijrobp.2010.01.057","article-title":"Post-radiation metabolic tumor volume predicts outcome in head-and-neck cancer","volume":"80","author":"Murphy","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0110","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0360-3016(02)02854-7","article-title":"Image fusion between 18FDG-PET and MRI\/CT for radiotherapy planning of oropharyngeal and nasopharyngeal carcinomas","volume":"53","author":"Nishioka","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0115","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.ijrobp.2004.08.037","article-title":"Comparison of CT- and FDG-PET-defined gross tumor volume in intensity-modulated radiotherapy for head-and-neck cancer","volume":"61","author":"Paulino","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2011.05.040_b0120","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1034\/j.1600-0714.2003.00060.x","article-title":"Invasive front grading: reliability and usefulness in the management of oral squamous cell carcinoma","volume":"32","author":"Sawair","year":"2003","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.radonc.2011.05.040_b0125","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.radonc.2009.02.007","article-title":"Can FDG-PET assist in radiotherapy target volume definition of metastatic lymph nodes in head-and-neck cancer?","volume":"91","author":"Schinagl","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0130","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.radonc.2008.03.008","article-title":"Screening for distant metastases in head and neck cancer patients by chest CT or whole body FDG-PET: a prospective multicenter trial","volume":"87","author":"Senft","year":"2008","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0135","first-page":"338","article-title":"Reliability of measuring volume by different methods for tumors of the musculoskeletal system","volume":"67","author":"Somville","year":"2001","journal-title":"Acta Orthop Belg"},{"key":"10.1016\/j.radonc.2011.05.040_b0140","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.radonc.2010.07.017","article-title":"Clinical evidence on PET\u2013CT for radiation therapy planning in head and neck tumours","volume":"96","author":"Troost","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.05.040_b0145","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1007\/s11307-006-0075-y","article-title":"Standardized uptake value atlas: characterization of physiological 2-deoxy-2-[18F]fluoro-d-glucose uptake in normal tissues","volume":"9","author":"Wang","year":"2007","journal-title":"Mol Imaging Biol"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814011002337?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814011002337?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T23:52:40Z","timestamp":1543708360000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814011002337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["S0167814011002337"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2011.05.040","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2011,12]]}}}