{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:06:35Z","timestamp":1791547595383,"version":"4.3.4"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,4,16]],"date-time":"2014-04-16T00:00:00Z","timestamp":1397606400000},"content-version":"vor","delay-in-days":562,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004622","name":"Dutch Cancer Society","doi-asserted-by":"crossref","award":["RUG 2008-3983"],"award-info":[{"award-number":["RUG 2008-3983"]}],"id":[{"id":"10.13039\/501100004622","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.radonc.2011.08.009","type":"journal-article","created":{"date-parts":[[2011,9,9]],"date-time":"2011-09-09T21:19:08Z","timestamp":1315603148000},"page":"107-114","source":"Crossref","is-referenced-by-count":253,"title":["Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study"],"prefix":"10.1016","volume":"105","author":[{"given":"Miranda E.M.C.","family":"Christianen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelis","family":"Schilstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivo","family":"Beetz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina T.","family":"Muijs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Chouvalova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred R.","family":"Burlage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Doornaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phil W.","family":"Koken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Ren\u00e9","family":"Leemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rico N.P.M.","family":"Rinkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke J.","family":"de Bruijn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.H.","family":"de Bock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan L.N.","family":"Roodenburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard F.A.M.","family":"van der Laan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben J.","family":"Slotman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irma M.","family":"Verdonck-de Leeuw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik P.","family":"Bijl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes A.","family":"Langendijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2011.08.009_b0005","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/j.otohns.2006.02.001","article-title":"Dysphagia after sequential chemoradiation therapy for advanced head and neck cancer","volume":"134","author":"Goguen","year":"2006","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.radonc.2011.08.009_b0010","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.radonc.2007.06.004","article-title":"Late swallowing dysfunction and dysphagia after radiotherapy for pharynx cancer: frequency, intensity and correlation with dose and volume parameters","volume":"85","author":"Jensen","year":"2007","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0015","doi-asserted-by":"crossref","first-page":"3770","DOI":"10.1200\/JCO.2007.14.6647","article-title":"Impact of late treatment-related toxicity on quality of life among patients with head and neck cancer treated with radiotherapy","volume":"26","author":"Langendijk","year":"2008","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0020","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1016\/j.ijrobp.2004.06.017","article-title":"Impact of dysphagia on quality of life after treatment of head-and-neck cancer","volume":"61","author":"Nguyen","year":"2005","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0025","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/01.mlg.0000250169.10241.58","article-title":"Distress in spouses and patients after treatment for head and neck cancer","volume":"117","author":"Verdonck-de Leeuw","year":"2007","journal-title":"Laryngoscope"},{"key":"10.1016\/j.radonc.2011.08.009_b0030","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.oraloncology.2009.11.001","article-title":"Employment and return to work in head and neck cancer survivors","volume":"46","author":"Verdonck-de Leeuw","year":"2010","journal-title":"Oral Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0035","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1016\/j.oraloncology.2011.05.012","article-title":"The impact of late treatment-toxicity on generic health-related quality of life in head and neck cancer patients after radiotherapy","volume":"47","author":"Ramaekers","year":"2011","journal-title":"Oral Oncol"},{"key":"10.1016\/j.radonc.2011.08.009_b0040","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijrobp.2008.07.059","article-title":"Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program","volume":"74","author":"Vergeer","year":"2009","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0045","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/hed.20672","article-title":"Swallowing disorders in the first year after radiation and chemoradiation","volume":"30","author":"Logemann","year":"2008","journal-title":"Head Neck"},{"key":"10.1016\/j.radonc.2011.08.009_b0050","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1097\/MOO.0b013e32832af12f","article-title":"Effects of chemoradiotherapy on voice and swallowing","volume":"17","author":"Lazarus","year":"2009","journal-title":"Curr. Opin. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.radonc.2011.08.009_b0055","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1044\/jslhr.4304.1011","article-title":"Swallowing and tongue function following treatment for oral and oropharyngeal cancer","volume":"43","author":"Lazarus","year":"2000","journal-title":"J. Speech Lang. Hear. Res."},{"key":"10.1016\/j.radonc.2011.08.009_b0060","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.radonc.2009.05.013","article-title":"Anatomical changes in the pharyngeal constrictors after chemo-irradiation of head and neck cancer and their dose-effect relationships: MRI-based study","volume":"93","author":"Popovtzer","year":"2009","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0065","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.ijrobp.2008.02.048","article-title":"Dose to larynx predicts for swallowing complications after intensity-modulated radiotherapy","volume":"72","author":"Caglar","year":"2008","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0070","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ijrobp.2009.02.017","article-title":"Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck","volume":"76","author":"Caudell","year":"2010","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0075","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.ijrobp.2007.01.047","article-title":"Radiation doses to structures within and adjacent to the larynx are correlated with long-term diet- and speech-related quality of life","volume":"68","author":"Dornfeld","year":"2007","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0080","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1016\/j.ijrobp.2007.04.083","article-title":"Can IMRT or brachytherapy reduce dysphagia associated with chemoradiotherapy of head and neck cancer? The Michigan and Rotterdam experiences","volume":"69","author":"Eisbruch","year":"2007","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0085","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/j.ijrobp.2004.05.050","article-title":"Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: which anatomic structures are affected and can they be spared by IMRT?","volume":"60","author":"Eisbruch","year":"2004","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0090","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.ijrobp.2007.02.049","article-title":"Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures","volume":"68","author":"Feng","year":"2007","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0095","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.ijrobp.2008.11.041","article-title":"Dysphagia after chemoradiotherapy for head-and-neck squamous cell carcinoma: dose-effect relationships for the swallowing structures","volume":"75","author":"Dirix","year":"2009","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0100","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.radonc.2008.12.017","article-title":"A predictive model for swallowing dysfunction after curative radiotherapy in head and neck cancer","volume":"90","author":"Langendijk","year":"2009","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0105","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.radonc.2007.07.009","article-title":"Dysphagia disorders in patients with cancer of the oropharynx are significantly affected by the radiation therapy dose to the superior and middle constrictor muscle: a dose-effect relationship","volume":"85","author":"Levendag","year":"2007","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0110","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.ijrobp.2008.04.048","article-title":"Factors associated with long-term dysphagia after definitive radiotherapy for locally advanced head-and-neck cancer","volume":"73","author":"Caudell","year":"2009","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0115","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/0360-3016(95)00060-C","article-title":"Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)","volume":"31","author":"Cox","year":"1995","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0120","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jnci\/85.5.365","article-title":"The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology","volume":"85","author":"Aaronson","year":"1993","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.radonc.2011.08.009_b0125","doi-asserted-by":"crossref","unstructured":"Bjordal K, de Graeff A, Fayers PM, et al. A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (EORTC QLQ-H&N35) in head and neck patients. EORTC Quality of Life Group. Eur. J. Cancer 2000;36:1796\u20131807.","DOI":"10.1016\/S0959-8049(00)00186-6"},{"key":"10.1016\/j.radonc.2011.08.009_b0130","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1200\/JCO.1999.17.3.1008","article-title":"Quality of life in head and neck cancer patients: validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H&N35","volume":"17","author":"Bjordal","year":"1999","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0135","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.radonc.2011.05.015","article-title":"Delineation of organs at risk involved in swallowing for radiotherapy treatment planning","volume":"101","author":"Christianen","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2011.08.009_b0205","doi-asserted-by":"crossref","unstructured":"van de Water TA, Bijl HP, Westerlaan HE, Langendijk JA. Delineation guidelines for organs at risk involved in radiation-induced salivary dysfunction and xerostomia. Radiother. Oncol. 2009;93:545-552.","DOI":"10.1016\/j.radonc.2009.09.008"},{"key":"10.1016\/j.radonc.2011.08.009_b0145","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1016\/j.ijrobp.2005.11.022","article-title":"Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors","volume":"64","author":"El Naqa","year":"2006","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0150","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.ijrobp.2006.10.028","article-title":"Intensity-modulated radiotherapy for nasopharyngeal carcinoma: clinical correlation of dose to the pharyngo-esophageal axis and dysphagia","volume":"67","author":"Fua","year":"2007","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0155","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.radonc.2008.07.012","article-title":"Results of fiberoptic endoscopic evaluation of swallowing vs Radiation dose in the swallowing muscles after radiotherapy of cancer in the oropharynx","volume":"89","author":"Teguh","year":"2008","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0160","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.ijrobp.2008.02.061","article-title":"Treatment techniques and site considerations regarding dysphagia-related quality of life in cancer of the oropharynx and nasopharynx","volume":"72","author":"Teguh","year":"2008","journal-title":"Int. J. Radiat. Oncol. Biol. Phys."},{"key":"10.1016\/j.radonc.2011.08.009_b0165","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.radonc.2009.09.017","article-title":"Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer","volume":"93","author":"Bhide","year":"2009","journal-title":"Radiother. Oncol."},{"key":"10.1016\/j.radonc.2011.08.009_b0170","doi-asserted-by":"crossref","unstructured":"Li B, Li D, Lau DH, et al. Clinical-dosimetric analysis of measures of dysphagia including gastrostomy-tube dependence among head and neck cancer patients treated definitively by intensity-modulated radiotherapy with concurrent chemotherapy. Radiat.Oncol. 2009;4:52.","DOI":"10.1186\/1748-717X-4-52"},{"key":"10.1016\/j.radonc.2011.08.009_b0175","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.bpg.2007.03.006","article-title":"Swallowing disorders","volume":"21","author":"Logemann","year":"2007","journal-title":"Best. Pract. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.radonc.2011.08.009_b0180","doi-asserted-by":"crossref","unstructured":"Logemann JA. Evaluation and treatment of swallowing disorders; 1998.","DOI":"10.1097\/00020840-199812000-00008"},{"key":"10.1016\/j.radonc.2011.08.009_b0185","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1002\/hed.20459","article-title":"Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy","volume":"28","author":"Pauloski","year":"2006","journal-title":"Head Neck"},{"key":"10.1016\/j.radonc.2011.08.009_b0190","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1001\/archotol.1988.01860240063025","article-title":"Timing of major events of pharyngeal swallowing","volume":"114","author":"McConnel","year":"1988","journal-title":"Arch. Otolaryngol. Head Neck Surg."},{"key":"10.1016\/j.radonc.2011.08.009_b0195","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.radonc.2010.08.013","article-title":"Characteristics of response of oral and pharyngeal mucosa in patients receiving chemo-IMRT for head and neck cancer using hypofractionated accelerated radiotherapy","volume":"97","author":"Bhide","year":"2010","journal-title":"Radiother. Oncol."}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814011004592?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814011004592?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,15]],"date-time":"2019-06-15T03:27:17Z","timestamp":1560569237000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814011004592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0167814011004592"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2011.08.009","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2012,10]]}}}