{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:40:56Z","timestamp":1789908056067,"version":"4.0.1"},"reference-count":14,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Health, Labour and Welfare of Japan"},{"name":"National Cancer Center Research and Development Fund","award":["23-A-21"],"award-info":[{"award-number":["23-A-21"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.radonc.2012.11.005","type":"journal-article","created":{"date-parts":[[2013,1,19]],"date-time":"2013-01-19T04:54:33Z","timestamp":1358571273000},"page":"85-89","source":"Crossref","is-referenced-by-count":80,"title":["Volume and dosimetric changes and initial clinical experience of a two-step adaptive intensity modulated radiation therapy (IMRT) scheme for head and neck cancer"],"prefix":"10.1016","volume":"106","author":[{"given":"Tamaki","family":"Nishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasumasa","family":"Nishimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Shibata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohiro","family":"Nishigaito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Okumura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2012.11.005_b0005","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.ijrobp.2006.06.013","article-title":"Xerostomia and quality of life after intensity-modulated radiotherapy vs. conventional radiotherapy for early-stage nasopharyngeal carcinoma: initial report on a randomized controlled clinical trial","volume":"66","author":"Pow","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0010","doi-asserted-by":"crossref","first-page":"4873","DOI":"10.1200\/JCO.2007.11.5501","article-title":"Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients","volume":"25","author":"Kam","year":"2007","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2012.11.005_b0015","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/j.ijrobp.2008.08.061","article-title":"Radiotherapy for head and neck cancer; is the \u201cnext level\u201d down?","volume":"73","author":"Mendenhall","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0020","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.ijrobp.2011.08.017","article-title":"Adaptive radiotherapy for head-and-neck cancer: initial clinical outcomes from a prospective trial","volume":"83","author":"Schwartz","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0025","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.ijrobp.2003.12.024","article-title":"Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT\/linear accelerator system","volume":"59","author":"Barker","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0030","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/jjco\/hyi108","article-title":"Importance of the initial volume of parotid glands in xerostomia for patients with head and neck cancers treated with IMRT","volume":"35","author":"Nishimura","year":"2005","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.radonc.2012.11.005_b0035","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1093\/jjco\/hyp136","article-title":"A two-step intensity-modulated radiation therapy method for nasopharyngeal cancer: the Kinki University experience","volume":"40","author":"Nishimura","year":"2010","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.radonc.2012.11.005_b0040","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.ijrobp.2007.09.018","article-title":"Recurrence in region of spared parotid gland after definitive intensity-modulated radiotherapy for head and neck cancer","volume":"70","author":"Cannon","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0045","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.ijrobp.2009.05.025","article-title":"Radiation treatment planning using positron emission and computed tomography (PET\/CT) for lung and pharyngeal cancers: a multiple thresholds method for FDG activity","volume":"77","author":"Okubo","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0050","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/j.ijrobp.2010.03.014","article-title":"Adaptive planning in intensity-modulated radiation therapy for head and neck cancers: single-institution experience and clinical implications","volume":"80","author":"Ahn","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0055","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.radonc.2010.10.009","article-title":"The role of replanning in fractionated intensity modulated radiotherapy for nasopharyngeal carcinoma","volume":"98","author":"Zhao","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2012.11.005_b0060","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ijrobp.2005.07.957","article-title":"Repeat CT imaging and replanning during the course of IMRT for head-and-neck cancer","volume":"64","author":"Hansen","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2012.11.005_b0065","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.radonc.2011.12.010","article-title":"Intensity-modulated radiotherapy in head and neck cancer: results of the prospective study GORTEC 2004\u201303","volume":"103","author":"Toledano","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2012.11.005_b0070","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1470-2045(10)70290-4","article-title":"Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial","volume":"12","author":"Nutting","year":"2011","journal-title":"Lancet Oncol"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016781401200518X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016781401200518X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T11:50:37Z","timestamp":1539949837000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016781401200518X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["S016781401200518X"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2012.11.005","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}