{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T18:19:08Z","timestamp":1759774748884},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.radonc.2014.10.008","type":"journal-article","created":{"date-parts":[[2014,11,4]],"date-time":"2014-11-04T17:53:27Z","timestamp":1415123607000},"page":"267-271","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Different treatment planning protocols can lead to large differences in organ at risk sparing"],"prefix":"10.1016","volume":"113","clinical-trial-number":[{"clinical-trial-number":"nct01302834","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct01880359","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Jim P.","family":"Tol","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max","family":"Dahele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Doornaert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ben J.","family":"Slotman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wilko F.A.R.","family":"Verbakel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2014.10.008_b0005","doi-asserted-by":"crossref","first-page":"3399","DOI":"10.1118\/1.2335486","article-title":"Approximating convex Pareto surfaces in multiobjective radiotherapy planning","volume":"33","author":"Craft","year":"2006","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0010","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.ijrobp.2012.05.045","article-title":"Pareto fronts in clinical practice for pinnacle","volume":"85","author":"Janssen","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0015","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1088\/0031-9155\/57\/10\/2943","article-title":"The dosimetric impact of leaf interdigitation and leaf width on VMAT treatment planning in pinnacle: comparing pareto fronts","volume":"57","author":"Van Kesteren","year":"2012","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.radonc.2014.10.008_b0020","doi-asserted-by":"crossref","first-page":"021722","DOI":"10.1118\/1.4862521","article-title":"Toward optimal organ at risk sparing in complex volumetric modulated arc therapy: an exponential trade-off with target volume dose homogeneity","volume":"41","author":"Tol","year":"2014","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0025","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.radonc.2003.09.011","article-title":"CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines.","volume":"69","author":"Gr\u00e9goire","year":"2003","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0030","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.radonc.2013.10.010","article-title":"Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines","volume":"110","author":"Gr\u00e9goire","year":"2014","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0035","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.radonc.2011.05.015","article-title":"Delineation of organs at risk involved in swallowing for radiotherapy treatment planning","volume":"101","author":"Christianen","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0040","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ijrobp.2009.11.014","article-title":"RapidArc planning and delivery in patients with locally advanced head-and-neck cancer undergoing chemoradiotherapy","volume":"79","author":"Doornaert","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0045","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/1748-717X-6-74","article-title":"Sparing the contralateral submandibular gland without compromising PTV coverage by using volumetric modulated arc therapy","volume":"6","author":"Doornaert","year":"2011","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0050","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.radonc.2012.03.004","article-title":"NTCP models for patient-rated xerostomia and sticky saliva after treatment with intensity modulated radiotherapy for head and neck cancer: the role of dosimetric and clinical factors","volume":"105","author":"Beetz","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0055","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ijrobp.2007.12.033","article-title":"Dose-effect relationships for the submandibular salivary glands and implications for their sparing by intensity modulated radiotherapy","volume":"72","author":"Murdoch-Kinch","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0060","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/j.ijrobp.2009.06.090","article-title":"Radiotherapy dose-volume effects on salivary gland function","volume":"76","author":"Deasy","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0065","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/j.ijrobp.2009.07.1708","article-title":"Parotid gland function after radiotherapy: the combined Michigan and Utrecht experience","volume":"78","author":"Dijkema","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0070","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/j.ijrobp.2007.02.049","article-title":"Intensity-modulated radiotherapy of head and neck cancer aiming to reduce dysphagia: early dose-effect relationships for the swallowing structures","volume":"68","author":"Feng","year":"2007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0075","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.radonc.2013.12.007","article-title":"Dose to the inferior pharyngeal constrictor predicts prolonged gastrostomy tube dependence with concurrent intensity-modulated radiation therapy and chemotherapy for locally-advanced head and neck cancer","volume":"110","author":"Vlacich","year":"2014","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.radonc.2011.08.009","article-title":"Predictive modelling for swallowing dysfunction after primary (chemo) radiation: results of a prospective observational study","volume":"105","author":"Christianen","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0085","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/j.ijrobp.2012.02.042","article-title":"Origin of tumor recurrence after intensity modulated radiation therapy for oropharyngeal squamous cell carcinoma","volume":"85","author":"Raktoe","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2014.10.008_b0090","first-page":"1","article-title":"Recurrences after intensity modulated radiotherapy for head and neck squamous cell carcinoma more likely to originate from regions with high baseline [18F]-FDG uptake","author":"Due","year":"2014","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0095","first-page":"1","article-title":"Patterns of failure after intensity-modulated radiotherapy in head and neck squamous cell carcinoma using compartmental clinical target volume delineation","volume":"D","author":"Bayman","year":"2014","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.1016\/j.radonc.2014.10.008_b0100","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S1470-2045(10)70290-4","article-title":"Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial","volume":"12","author":"Nutting","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2014.10.008_b0105","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.clon.2007.07.001","article-title":"Target volume definition for head and neck intensity modulated radiotherapy: pre-clinical evaluation of PARSPORT trial guidelines","volume":"19","author":"Guerrero Urbano","year":"2007","journal-title":"Clin Oncol (R Coll Radiol)"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814014004162?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814014004162?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,27]],"date-time":"2018-09-27T21:24:46Z","timestamp":1538083486000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814014004162"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S0167814014004162"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2014.10.008","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Different treatment planning protocols can lead to large differences in organ at risk sparing","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2014.10.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}