{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T02:45:39Z","timestamp":1770777939143,"version":"3.50.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004895","name":"ESF","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Greek National Funds"}],"content-domain":{"domain":["thegreenjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.radonc.2016.01.022","type":"journal-article","created":{"date-parts":[[2016,2,9]],"date-time":"2016-02-09T09:18:31Z","timestamp":1455009511000},"page":"92-97","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["On the impact of improved dosimetric accuracy on head and neck high dose rate brachytherapy"],"prefix":"10.1016","volume":"120","author":[{"given":"Vasiliki","family":"Peppa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleftherios","family":"Pappas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tibor","family":"Major","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Tak\u00e1csi-Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evaggelos","family":"Pantelis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6122-9624","authenticated-orcid":false,"given":"Panagiotis","family":"Papagiannis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2016.01.022_b0005","doi-asserted-by":"crossref","first-page":"6208","DOI":"10.1118\/1.4747264","article-title":"Report of the Task Group 186 on model-based dose calculation methods in brachytherapy beyond the TG-43 formalism: current status and recommendations for clinical implementation","volume":"39","author":"Davis","year":"2012","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0010","doi-asserted-by":"crossref","first-page":"20140163","DOI":"10.1259\/bjr.20140163","article-title":"Current state of the art brachytherapy treatment planning dosimetry algorithms","volume":"87","author":"Papagiannis","year":"2014","journal-title":"Br J Radiol"},{"key":"10.1016\/j.radonc.2016.01.022_b0015","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.radonc.2013.09.010","article-title":"Monte Carlo dosimetry of high dose rate gynecologic interstitial brachytherapy","volume":"109","author":"Desbiens","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.01.022_b0020","doi-asserted-by":"crossref","first-page":"232","DOI":"10.5114\/jcb.2013.39444","article-title":"Head and neck (192)Ir HDR-brachytherapy dosimetry using a grid-based Boltzmann solver","volume":"5","author":"Siebert","year":"2013","journal-title":"J Contemp Brachyther"},{"key":"10.1016\/j.radonc.2016.01.022_b0025","first-page":"1","article-title":"A retrospective dosimetric comparison of TG43 and a commercially available MBDCA for an APBI brachytherapy patient cohort","author":"Zourari","year":"2015","journal-title":"Phys Med"},{"key":"10.1016\/j.radonc.2016.01.022_b0030","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.radonc.2009.01.005","article-title":"GEC-ESTRO recommendations for brachytherapy for head and neck squamous cell carcinomas","volume":"91","author":"Mazeron","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.01.022_b0035","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.radonc.2007.04.002","article-title":"Evidence-based radiation oncology in head and neck squamous cell carcinoma","volume":"85","author":"Corv\u00f2","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.01.022_b0040","doi-asserted-by":"crossref","first-page":"298","DOI":"10.13182\/NT11-135","article-title":"Initial MCNP6 release overview","volume":"180","author":"Goorley","year":"2012","journal-title":"Nucl Technol"},{"key":"10.1016\/j.radonc.2016.01.022_b0045","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1120\/jacmp.v16i1.5136","article-title":"BrachyGuide: a brachytherapy-dedicated DICOM RT viewer and interface to Monte Carlo simulation software","volume":"16","author":"Pantelis","year":"2015","journal-title":"J Appl Clin Med Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1040-8428(03)00026-X","article-title":"Inter-society standards for the performance of brachytherapy: a joint report from ABS, ACMP and ACRO","volume":"48","author":"Nag","year":"2003","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.radonc.2016.01.022_b0055","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.brachy.2013.07.001","article-title":"Long-term outcomes with high-dose-rate brachytherapy for the management of base of tongue cancer","volume":"12","author":"Tak\u00e1csi-Nagy","year":"2013","journal-title":"Brachytherapy"},{"key":"10.1016\/j.radonc.2016.01.022_b0060","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S0360-3016(97)00732-3","article-title":"A conformal index (COIN) to evaluate implant quality and dose specification in brachytherapy","volume":"40","author":"Baltas","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0065","doi-asserted-by":"crossref","first-page":"N101","DOI":"10.1088\/0031-9155\/59\/13\/N101","article-title":"Two non-parametric methods for derivation of constraints from radiotherapy dose-histogram data","volume":"59","author":"Ebert","year":"2014","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.radonc.2016.01.022_b0070","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.ijrobp.2008.11.039","article-title":"Sensitivity analysis of parameters in linear-quadratic radiobiologic modeling","volume":"73","author":"Fowler","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0075","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0167-8140(99)00042-0","article-title":"Fractionation sensitivities and dose-control relations of head and neck carcinomas: analysis of the randomized hyperfractionation trials","volume":"51","author":"Stuschke","year":"1999","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.01.022_b0080","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1118\/1.598063","article-title":"Reporting and analyzing dose distributions: a concept of equivalent uniform dose","volume":"24","author":"Niemierko","year":"1997","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0085","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3390\/cancers4020566","article-title":"An estimation of radiobiological parameters for head-and-neck cancer cells and the clinical implications","volume":"4","author":"Qi","year":"2012","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.radonc.2016.01.022_b0090","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1053\/ejso.1999.0907","article-title":"Cell production rates in human tissues and tumours and their significance. Part II: clinical data","volume":"26","author":"Rew","year":"2000","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.radonc.2016.01.022_b0095","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.radonc.2007.07.004","article-title":"Comparison of three accelerated partial breast irradiation techniques: treatment effectiveness based upon biological models","volume":"84","author":"Bovi","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.01.022_b0100","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S0360-3016(97)00096-5","article-title":"Calculation of integrated biological response in brachytherapy","volume":"38","author":"Dale","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0105","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.2307\/3583506","article-title":"Complication probability as assessed from dose\u2013volume histograms","volume":"8","author":"Lyman","year":"1985","journal-title":"Radiat Res Suppl"},{"key":"10.1016\/j.radonc.2016.01.022_b0110","doi-asserted-by":"crossref","first-page":"1623","DOI":"10.1016\/0360-3016(89)90972-3","article-title":"Calculation of complication probability factors for non-uniform normal tissue irradiation: the effective volume method","volume":"16","author":"Kutcher","year":"1989","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0115","article-title":"A generalized concept of equivalent uniform dose ({EUD})","volume":"26","author":"Niemierko","year":"1999","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0120","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1088\/0031-9155\/53\/3\/014","article-title":"Lyman\u2013Kutcher\u2013Burman NTCP model parameters for radiation pneumonitis and xerostomia based on combined analysis of published clinical data","volume":"53","author":"Semenenko","year":"2008","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.radonc.2016.01.022_b0125","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0360-3016(91)90171-Y","article-title":"Tolerance of normal tissue to therapeutic irradiation","volume":"21","author":"Emami","year":"1991","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0130","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0360-3016(91)90172-Z","article-title":"Fitting of normal tissue tolerance data to an analytic function","volume":"21","author":"Burman","year":"1991","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0135","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0167-8140(97)00092-3","article-title":"Analysis of risk factors for mandibular bone radionecrosis after exclusive low dose-rate brachytherapy for oral cancer","volume":"44","author":"Lozza","year":"1997","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.01.022_b0140","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1088\/0031-9155\/60\/11\/4565","article-title":"Dose specification for 192Ir high dose rate brachytherapy in terms of dose-to-water-in-medium and dose-to-medium-in-medium","volume":"60","author":"Fonseca","year":"2015","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.radonc.2016.01.022_b0145","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1088\/0031-9155\/58\/4\/1123","article-title":"On the biological basis for competing macroscopic dose descriptors for kilovoltage dosimetry: cellular dosimetry for brachytherapy and diagnostic radiology","volume":"58","author":"Thomson","year":"2013","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.radonc.2016.01.022_b0150","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1016\/j.ijrobp.2004.12.065","article-title":"The effect of finite patient dimensions and tissue inhomogeneities on dosimetry planning of 192Ir HDR breast brachytherapy: a Monte Carlo dose verification study","volume":"61","author":"Pantelis","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0155","doi-asserted-by":"crossref","first-page":"011712","DOI":"10.1118\/1.4770275","article-title":"Dosimetric accuracy of a deterministic radiation transport based (192)Ir brachytherapy treatment planning system. Part III. Comparison to Monte Carlo simulation in voxelized anatomical computational models","volume":"40","author":"Zourari","year":"2013","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2016.01.022_b0160","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.radonc.2013.11.002","article-title":"Review of clinical brachytherapy uncertainties: analysis guidelines of GEC-ESTRO and the AAPM","volume":"110","author":"Kirisits","year":"2014","journal-title":"Radiother Oncol"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016000530?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016000530?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,15]],"date-time":"2018-09-15T11:30:12Z","timestamp":1537011012000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814016000530"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0167814016000530"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2016.01.022","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"On the impact of improved dosimetric accuracy on head and neck high dose rate brachytherapy","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2016.01.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}