{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T21:52:14Z","timestamp":1790545934544,"version":"4.1.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,16]],"date-time":"2016-06-16T00:00:00Z","timestamp":1466035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["thegreenjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2016,7]]},"DOI":"10.1016\/j.radonc.2016.05.025","type":"journal-article","created":{"date-parts":[[2016,6,23]],"date-time":"2016-06-23T16:01:14Z","timestamp":1466697674000},"page":"36-40","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"title":["Selection of head and neck cancer patients for adaptive radiotherapy to decrease xerostomia"],"prefix":"10.1016","volume":"120","author":[{"given":"Charlotte L.","family":"Brouwer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roel J.H.M.","family":"Steenbakkers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjen","family":"van der Schaaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal T.C.","family":"Sopacua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisanne V.","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roel G.J.","family":"Kierkels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hendrik P.","family":"Bijl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes G.M.","family":"Burgerhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes A.","family":"Langendijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanna M.","family":"Sijtsema","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2016.05.025_b0005","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/j.ijrobp.2009.04.047","article-title":"Adaptive replanning strategies accounting for shrinkage in head and neck IMRT","volume":"75","author":"Wu","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.05.025_b0010","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.radonc.2012.10.010","article-title":"Adaptive radiotherapy for head and neck cancer-dosimetric results from a prospective clinical trial","volume":"106","author":"Schwartz","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0015","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s00066-011-0041-8","article-title":"Adaptive radiotherapy for soft tissue changes during helical tomotherapy for head and neck cancer","volume":"188","author":"Duma","year":"2012","journal-title":"Strahlenther Onkol"},{"key":"10.1016\/j.radonc.2016.05.025_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2015.06.025","article-title":"Predicting the need for adaptive radiotherapy in head and neck cancer","author":"Brown","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0025","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.radonc.2015.05.018","article-title":"Identifying patients who may benefit from adaptive radiotherapy: Does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help?","volume":"115","author":"Brouwer","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0030","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13014-014-0318-z","article-title":"Impact of head and neck cancer adaptive radiotherapy to spare the parotid glands and decrease the risk of xerostomia","volume":"10","author":"Castelli","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0035","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.radonc.2011.06.011","article-title":"Adaptive functional image-guided IMRT in pharyngo-laryngeal squamous cell carcinoma: Is the gain in dose distribution worth the effort?","volume":"101","author":"Castadot","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0040","article-title":"Predictive modelling for swallowing dysfunction after primary (chemo)radiation: Results of a prospective observational study","author":"Christianen","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0045","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1371\/journal.pone.0094879","article-title":"Development and validation of a prediction model for tube feeding dependence after curative (Chemo-) radiation in head and neck cancer","volume":"9","author":"Wopken","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1016\/j.radonc.2016.05.025_b0050","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.radonc.2012.03.004","article-title":"NTCP models for patient-rated xerostomia and sticky saliva after treatment with intensity modulated radiotherapy for head and neck cancer: the role of dosimetric and clinical factors","volume":"105","author":"Beetz","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0055","doi-asserted-by":"crossref","first-page":"e351","DOI":"10.1016\/j.ijrobp.2012.05.020","article-title":"A prospective cohort study on radiation-induced hypothyroidism: development of an NTCP model","volume":"84","author":"Boomsma","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.05.025_b0060","first-page":"1","article-title":"A quantitative assessment of volumetric and anatomic changes of the parotid gland during intensity-modulated radiotherapy for head and neck cancer using serial computed tomography","author":"Ajani","year":"2013","journal-title":"Med Dosim"},{"key":"10.1016\/j.radonc.2016.05.025_b0065","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1002\/lary.20601","article-title":"Radiation-induced volume changes in parotid and submandibular glands in patients with head and neck cancer receiving postoperative radiotherapy: a longitudinal study","volume":"119","author":"Wang","year":"2009","journal-title":"Laryngoscope"},{"key":"10.1016\/j.radonc.2016.05.025_b0070","first-page":"285","article-title":"Identifying patients who may benefit from adaptive radiotherapy: Does the literature on anatomic and dosimetric changes in head and neck organs at risk during radiotherapy provide information to help?","volume":"115","author":"Brouwer","year":"2015"},{"key":"10.1016\/j.radonc.2016.05.025_b0075","first-page":"267","article-title":"Selection of patients for radiotherapy with protons aiming at reduction of side effects: the model-based approach","volume":"107","author":"Langendijk","year":"2013"},{"key":"10.1016\/j.radonc.2016.05.025_b0080","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.radonc.2009.12.014","article-title":"A two-variable linear model of parotid shrinkage during IMRT for head and neck cancer","volume":"94","author":"Broggi","year":"2010","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0085","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1007\/s11547-014-0386-z","article-title":"Volumetric and positional changes of planning target volumes and organs at risk using computed tomography imaging during intensity-modulated radiation therapy for head\u2013neck cancer: an \u201cold\u201d adaptive radiation therapy approach","volume":"119","author":"Reali","year":"2014","journal-title":"Radiol Med"},{"key":"10.1016\/j.radonc.2016.05.025_b0090","doi-asserted-by":"crossref","first-page":"20130363","DOI":"10.1259\/bjr.20130363","article-title":"Pattern and predictors of volumetric change of parotid glands during intensity modulated radiotherapy","volume":"86","author":"Sanguineti","year":"2013","journal-title":"Br J Radiol"},{"key":"10.1016\/j.radonc.2016.05.025_b0095","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13014-015-0331-x","article-title":"Parotid gland shrinkage during IMRT predicts the time to Xerostomia resolution","volume":"10","author":"Sanguineti","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0100","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/j.ijrobp.2007.10.063","article-title":"Local anatomic changes in parotid and submandibular glands during radiotherapy for oropharynx cancer and correlation with dose, studied in detail with nonrigid registration","volume":"70","author":"V\u00e1squez Osorio","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.05.025_b0105","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.meddos.2009.06.007","article-title":"Anatomic and dosimetric changes during the treatment course of intensity-modulated radiotherapy for locally advanced nasopharyngeal carcinoma","volume":"35","author":"Wang","year":"2010","journal-title":"Med Dosim"},{"key":"10.1016\/j.radonc.2016.05.025_b0110","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/j.ijrobp.2009.07.1685","article-title":"A comparison of dose-response models for the parotid gland in a large group of head-and-neck cancer patients","volume":"76","author":"Houweling","year":"2010","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.05.025_b0115","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1016\/j.ijrobp.2012.09.033","article-title":"Replanning during intensity modulated radiation therapy improved quality of life in patients with nasopharyngeal carcinoma","volume":"85","author":"Yang","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.05.025_b0120","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.radonc.2010.10.009","article-title":"The role of replanning in fractionated intensity modulated radiotherapy for nasopharyngeal carcinoma","volume":"98","author":"Zhao","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.05.025_b0125","first-page":"811","article-title":"Replanning during intensity modulated radiation therapy improved quality of life in patients with nasopharyngeal carcinoma: in regard to Yang et al.","volume":"86","author":"Levy","year":"2013"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016311495?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016311495?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T02:23:19Z","timestamp":1536632599000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814016311495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["S0167814016311495"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2016.05.025","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2016,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selection of head and neck cancer patients for adaptive radiotherapy to decrease xerostomia","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2016.05.025","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Author(s). Published by Elsevier Ireland Ltd.","name":"copyright","label":"Copyright"}]}}