{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T16:08:49Z","timestamp":1774368529073,"version":"3.50.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T00:00:00Z","timestamp":1472688000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["thegreenjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1016\/j.radonc.2016.07.003","type":"journal-article","created":{"date-parts":[[2016,9,10]],"date-time":"2016-09-10T00:33:48Z","timestamp":1473467628000},"page":"455-459","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Preoperative image-guided brachytherapy in early stage cervical cancers"],"prefix":"10.1016","volume":"120","clinical-trial-number":[{"clinical-trial-number":"nct01658930","registry":"10.18810\/clinical-trials-gov"}],"author":[{"given":"Alexandre","family":"Escande","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renaud","family":"Mazeron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastien","family":"Gouy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrica","family":"Bentivegna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Maroun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georges","family":"Fahra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Sophie","family":"Oberlander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Dumas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pauline","family":"Castelnau-Marchand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Deutsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippe","family":"Morice","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Haie-Meder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cyrus","family":"Chargari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2016.07.003_b0005","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.radonc.2004.12.015","article-title":"Recommendations from Gynaecological (GYN) GEC ESTRO Working Group (I): concepts and terms in 3D image-based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV","volume":"74","author":"Haie-Meder","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0010","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.radonc.2007.04.012","article-title":"Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer","volume":"83","author":"P\u00f6tter","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0015","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.radonc.2009.07.001","article-title":"Dose\u2013effect relationship for local control of cervical cancer by magnetic resonance image guided brachytherapy","volume":"93","author":"Dimopoulos","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0020","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ijrobp.2008.06.1912","article-title":"Physics contribution and clinical outcome with 3D-MRI-based pulsed-dose-rate intracavitary brachytherapy in cervical cancer patients","volume":"74","author":"Chargari","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.003_b0025","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.radonc.2014.11.045","article-title":"Impact of treatment time and dose escalation on local control in locally advanced cervical cancer treated by chemoradiation and image-guided pulsed-dose rate adaptive brachytherapy","volume":"114","author":"Mazeron","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0030","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.3109\/0284186X.2013.818253","article-title":"MRI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective","volume":"52","author":"Lindegaard","year":"2013","journal-title":"Acta Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0035","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.radonc.2012.04.007","article-title":"Impact of 3D image-based PDR brachytherapy on outcome of patients treated for cervix carcinoma in France: results of the French STIC prospective study","volume":"103","author":"Charra-Brunaud","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0040","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0167-8140(92)90337-T","article-title":"Combined radiotherapy and surgery: local control and complications in early carcinoma of the uterine cervix \u2013 the Villejuif experience, 1975\u20131984","volume":"23","author":"Gerbaulet","year":"1992","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0045","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/0167-8140(92)90351-T","article-title":"Preoperative radiation therapy and surgery in the treatment of \u00abbulky\u00bb squamous cell carcinoma of the uterine cervix (stage Ib, IIa, and IIb operable tumors)","volume":"24","author":"Touboul","year":"1992","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0050","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0140-6736(97)02250-2","article-title":"Randomized study of radical surgery versus radiotherapy for stage Ib-IIa cervical cancer","volume":"350","author":"Landoni","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.radonc.2016.07.003_b0055","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S0360-3016(99)00217-5","article-title":"Lack of effect of tumor size on the prognosis of carcinoma of the uterine cervix stage IB and IIA treated with preoperative irradiation and surgery","volume":"45","author":"Grigsby","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.003_b0060","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/00000421-199902000-00018","article-title":"Preoperative intracavitary brachytherapy in early-stage cervical carcinoma","volume":"22","author":"Mundt","year":"1999","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0065","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0360-3016(01)01602-9","article-title":"Combined brachytherapy and surgery for early carcinoma of the uterine cervix: analysis of extent of surgery on outcome","volume":"50","author":"Resbeut","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.003_b0070","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0360-3016(02)02971-1","article-title":"Operable Stages IB and II cervical carcinomas: a retrospective study comparing preoperative uterovaginal brachytherapy and postoperative radiotherapy","volume":"54","author":"Atlan","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.003_b0075","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S1278-3218(02)00148-8","article-title":"Epidermoid carcinoma of the uterine cervix at operable bulky stages IB and II treated with combined primary radiation therapy and surgery","volume":"6","author":"Bernard","year":"2002","journal-title":"Cancer Radiother"},{"key":"10.1016\/j.radonc.2016.07.003_b0080","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0090-8258(03)00173-2","article-title":"Radiation therapy with and without extrafascial hysterectomy for bulky stage IB cervical carcinoma: a randomized-trial of the Gynecologic Oncology Group","volume":"89","author":"Keys","year":"2003","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0085","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/j.ijrobp.2008.03.054","article-title":"Preoperative concurrent radiation therapy and chemotherapy for bulky IB2, IIA and IIB carcinoma of the uterine cervix with proximal parametrial invasion","volume":"72","author":"Huguet","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.003_b0090","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.radonc.2009.05.004","article-title":"DVH parameters and outcome for patients with early-stage cervical cancer treated with preoperative MRI-based low dose rate brachytherapy followed by surgery","volume":"93","author":"Haie-Meder","year":"2009","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0095","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/j.ygyno.2011.08.011","article-title":"Outcome in early cervical cancer following pre-operative low dose rate brachytherapy: a ten-year follow up of 257 patients treated at a single institution","volume":"132","author":"Ng\u00f4","year":"2011","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0100","doi-asserted-by":"crossref","first-page":"e49","DOI":"10.1016\/j.ijrobp.2011.01.022","article-title":"Prospective multi-institutional study of definitive radiotherapy with high dose rate intracavitary brachytherapy in patients with nonbulky (<4cm) stage I and II uterin cervical cancer (JAROG0401\/JROSG04-2)","volume":"82","author":"Toita","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.003_b0105","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1245\/s10434-012-2630-x","article-title":"Laparoscopic radical hysterectomy after preoperative brachytherapy for stage Ib1 cervical cancer: feasibility, results, and surgical implications in a large bicentric study of 162 consecutive cases","volume":"20","author":"Uzan","year":"2013","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0110","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.ejso.2015.12.003","article-title":"Early stage cervical cancer: Brachytherapy followed by type a hysterectomy versus type B radical hysterectomy alone, a retrospective evaluation","volume":"42","author":"Lacorre","year":"2016","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0115","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/aogs.12819","article-title":"Results of radical surgery in women with stage IB2\/IIA2 cervical cancer","volume":"95","author":"Derks","year":"2016","journal-title":"Acta Obstet Gynecol Scand"},{"key":"10.1016\/j.radonc.2016.07.003_b0120","first-page":"333","article-title":"Standards, options and recommendations for the management of invasive cervical cancer patients (non metastastic)","volume":"90","author":"Resbeut","year":"2003","journal-title":"Bull Cancer"},{"key":"10.1016\/j.radonc.2016.07.003_b0125","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1006\/gyno.1999.5387","article-title":"A randomized trial of pelvic radiation therapy versus no further therapy in selected patients with stage IB carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: A Gynecologic Oncology Group Study","volume":"73","author":"Sedlis","year":"1999","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0130","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ijrobp.2005.10.019","article-title":"A phase III randomized trial of postoperative pelvic irradiation in Stage IB cervical carcinoma with poor prognostic features: follow-up of a gynecologic oncology group study","volume":"65","author":"Rotman","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys."},{"key":"10.1016\/j.radonc.2016.07.003_b0135","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S1470-2045(08)70074-3","article-title":"Classification of radical hysterectomy","volume":"9","author":"Querleu","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0140","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1006\/gyno.2000.6010","article-title":"Class II versus class III radical hysterectomy in stage IB-IIA cervical cancer: a prospective randomized study","volume":"80","author":"Landoni","year":"2001","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0145","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.ejso.2011.12.017","article-title":"Class I versus class III radical hysterectomy in stage IB1-IIA cervical cancer. A prospective randomized study","volume":"38","author":"Landoni","year":"2012","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.radonc.2016.07.003_b0150","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1245\/s10434-012-2630-x","article-title":"Laparoscopic radical hysterectomy after preoperative brachytherapy for stage IB1 cervical cancer: feasibility, results, and surgical implications in a large bicentric study of 162 consecutive cases","volume":"20","author":"Uzan","year":"2013","journal-title":"Ann Surg Oncol"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016311951?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016311951?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T10:28:50Z","timestamp":1568370530000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814016311951"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,9]]}},"alternative-id":["S0167814016311951"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2016.07.003","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2016,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preoperative image-guided brachytherapy in early stage cervical cancers","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2016.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}