{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T07:24:25Z","timestamp":1789802665702,"version":"4.0.1"},"reference-count":28,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100008363","name":"Danish Cancer Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008363","id-type":"DOI","asserted-by":"publisher"}]},{"name":"CIRRO"},{"DOI":"10.13039\/100007210","name":"Varian Medical Systems","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thegreenjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.radonc.2016.07.015","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T18:23:42Z","timestamp":1470248622000},"page":"52-58","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Cardiac and respiration induced motion of mediastinal lymph node targets in lung cancer patients throughout the radiotherapy treatment course"],"prefix":"10.1016","volume":"121","author":[{"given":"Mai Lykkegaard","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lone","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne Marquard","family":"Knap","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torben Riis","family":"Rasmussen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgitte Holst","family":"Folkersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Toftegaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ditte Sloth","family":"M\u00f8ller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per Rug\u00e5rd","family":"Poulsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2016.07.015_b0005","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1097\/JTO.0b013e3182429682","article-title":"Defining local-regional control and its importance in locally advanced non-small cell lung carcinoma","volume":"7","author":"Machtay","year":"2012","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0010","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.ijrobp.2010.09.004","article-title":"Higher biologically effective dose of radiotherapy is associated with improved outcomes for locally advanced non-small cell lung carcinoma treated with chemoradiation: an analysis of the Radiation Therapy Oncology Group","volume":"82","author":"Machtay","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0015","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.ijrobp.2005.02.010","article-title":"High-dose radiation improved local tumor control and overall survival in patients with inoperable\/unresectable non-small-cell lung cancer: long-term results of a radiation dose escalation study","volume":"63","author":"Kong","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0020","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1470-2045(14)71207-0","article-title":"Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial p","volume":"16","author":"Bradley","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0025","doi-asserted-by":"crossref","first-page":"3874","DOI":"10.1118\/1.2349696","article-title":"The management of respiratory motion in radiation oncology report of AAPM Task Group 76","volume":"33","author":"Keall","year":"2006","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0030","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0360-3016(02)02803-1","article-title":"Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy","volume":"53","author":"Seppenwoolde","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0035","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.radonc.2013.10.013","article-title":"Adaptive radiotherapy of lung cancer patients with pleural effusion or atelectasis","volume":"110","author":"M\u00f8ller","year":"2014","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0040","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.3109\/0284186X.2013.815798","article-title":"Dosimetric impact of respiratory motion, interfraction baseline shifts, and anatomical changes in radiotherapy of non-small cell lung cancer","volume":"52","author":"Schmidt","year":"2013","journal-title":"Acta Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0045","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/j.ijrobp.2008.09.048","article-title":"Tumor localization using cone-beam CT reduces setup margins in conventionally fractionated radiotherapy for lung tumors","volume":"74","author":"Yeung","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0050","first-page":"9","article-title":"Anatomical landmarks accurately determine interfractional lymph node shifts during radiotherapy of lung cancer patients","author":"Hoffmann","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0055","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.radonc.2012.09.007","article-title":"Mediastinal lymph node position variability in non-small cell lung cancer patients treated with radical irradiation","volume":"105","author":"Schaake","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0060","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.ijrobp.2013.09.050","article-title":"Interfraction displacement of primary tumor and involved lymph nodes relative to anatomic landmarks in image guided radiation therapy of locally advanced lung cancer","volume":"88","author":"Jan","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0065","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/j.ijrobp.2008.09.031","article-title":"Motion analysis of 100 mediastinal lymph nodes: potential pitfalls in treatment planning and adaptive strategies","volume":"74","author":"Pantarotto","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0070","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.ijrobp.2014.07.038","article-title":"Differential motion between mediastinal lymph nodes and primary tumor in radically irradiated lung cancer patients","volume":"90","author":"Schaake","year":"2014","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0075","doi-asserted-by":"crossref","first-page":"1587","DOI":"10.1016\/j.ijrobp.2008.07.037","article-title":"A method to estimate mean position, motion magnitude, motion correlation, and trajectory of a tumor from cone-beam CT projections for image-guided radiotherapy","volume":"72","author":"Poulsen","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0080","doi-asserted-by":"crossref","first-page":"e655","DOI":"10.1016\/j.ijrobp.2012.07.2367","article-title":"Kilovoltage intrafraction monitoring for prostate intensity modulated arc therapy: first clinical results","volume":"84","author":"Ng","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0085","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.ijrobp.2014.09.040","article-title":"Six degrees-of-freedom prostate and lung tumor motion measurements using kilovoltage intrafraction monitoring","volume":"91","author":"Huang","year":"2015","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0090","first-page":"217","article-title":"Kilovoltage intrafraction motion monitoring and target dose reconstruction for stereotactic volumetric modulated arc therapy of tumors in the liver","volume":"115","author":"Poulsen","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0095","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.radonc.2015.03.029","article-title":"Adaptive motion mapping in pancreatic SBRT patients using Fourier transforms","volume":"115","author":"Jones","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0100","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1378\/chest.111.6.1718","article-title":"Regional lymph node classification for lung cancer staging","volume":"111","author":"Mountain","year":"1997","journal-title":"Chest"},{"key":"10.1016\/j.radonc.2016.07.015_b0105","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/JTO.0b013e3181622bdd","article-title":"Image-guided radiation therapy for non-small cell lung cancer","volume":"3","author":"Chang","year":"2008","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0110","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1118\/1.3555295","article-title":"A method for robust segmentation of arbitrarily shaped radiopaque structures in cone-beam CT projections","volume":"38","author":"Poulsen","year":"2011","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0115","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1053\/j.semradonc.2003.10.003","article-title":"Errors and margins in radiotherapy","volume":"14","author":"van Herk","year":"2004","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0120","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1118\/1.4904023","article-title":"The first clinical treatment with kilovoltage intrafraction monitoring (KIM): A real-time image guidance method","volume":"42","author":"Keall","year":"2015","journal-title":"Med Phys"},{"key":"10.1016\/j.radonc.2016.07.015_b0125","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1186\/s13014-015-0435-3","article-title":"Respiratory motion variability of primary tumors and lymph nodes during radiotherapy of locally advanced non-small-cell lung cancers","volume":"10","author":"Jan","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.radonc.2016.07.015_b0130","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jvir.2008.09.026","article-title":"Safety and efficacy of percutaneous fiducial marker implantation for image-guided radiation therapy","volume":"20","author":"Kothary","year":"2009","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.radonc.2016.07.015_b0135","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1007\/s00270-011-0242-7","article-title":"Airway migration of lung fiducial marker after autologous blood-patch injection","volume":"35","author":"Lee","year":"2012","journal-title":"Cardiovasc Intervent Radiol"},{"key":"10.1016\/j.radonc.2016.07.015_b0140","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1378\/chest.07-0522","article-title":"Electromagnetic navigation bronchoscopy-guided fiducial placement for robotic stereotactic radiosurgery of lung tumors: a feasibility study","volume":"132","author":"Anantham","year":"2007","journal-title":"CHEST J"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016312117?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814016312117?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,9]],"date-time":"2018-09-09T17:23:24Z","timestamp":1536513804000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814016312117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["S0167814016312117"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2016.07.015","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cardiac and respiration induced motion of mediastinal lymph node targets in lung cancer patients throughout the radiotherapy treatment course","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2016.07.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ireland Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}