{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:17:46Z","timestamp":1792275466312,"version":"4.4.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100011676","name":"Elekta","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011676","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007210","name":"Varian Medical Systems","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007210","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.radonc.2019.08.004","type":"journal-article","created":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T08:43:16Z","timestamp":1567672996000},"page":"123-129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Vienna-II ring applicator for distal parametrial\/pelvic wall disease in cervical cancer brachytherapy: An experience from two institutions: Clinical feasibility and outcome"],"prefix":"10.1016","volume":"141","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8391-4956","authenticated-orcid":false,"given":"Umesh","family":"Mahantshetty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Sturdza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pushpa","family":"Naga CH","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israel","family":"Fortin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Motisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian P.","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dheera","family":"Aravindakshan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yogesh","family":"Ghadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamema V.","family":"Swamidas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supriya","family":"Chopra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lavanya","family":"Gurram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Nesvacil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2815-8083","authenticated-orcid":false,"given":"Christian","family":"Kirisits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"P\u00f6tter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2019.08.004_b0005","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/j.ijrobp.2006.01.036","article-title":"The Vienna applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: design, application, treatment planning, and dosimetric results","volume":"65","author":"Kirisits","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0010","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.ijrobp.2011.04.044","article-title":"Clinical use of the Utrecht applicator for combined intracavitary\/interstitial brachytherapy treatment in locally advanced cervical cancer","volume":"82","author":"Nomden","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0015","first-page":"1","article-title":"Transperineal interstitial-intracavitary \u201cSyed-Neblett\u201d applicator in the treatment of carcinoma of the uterine cervix","volume":"2","author":"Syed","year":"1986","journal-title":"Endocurie Hypertherm Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0020","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0360-3016(84)90016-6","article-title":"A multiple-site perineal applicator (MUPIT) for treatment of prostatic, anorectal, and gynecological malignancies","volume":"10","author":"Martinez","year":"1984","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0025","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0360-3016(99)00124-8","article-title":"High dose rate transperineal interstitial brachytherapy for cervical cancer: high pelvic control and low complication rates","volume":"45","author":"Demanes","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0030","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.ijrobp.2006.04.041","article-title":"The Vienna applicator for combined intracavitary and interstitial brachytherapy of cervical cancer: clinical feasibility and preliminary results","volume":"66","author":"Dimopoulos","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0035","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.radonc.2013.01.010","article-title":"Clinical feasibility of combined intracavitary\/interstitial brachytherapy in locally advanced cervical cancer employing MRI with a tandem\/ring applicator in situ and virtual preplanning of the interstitial component","volume":"107","author":"Fokdal","year":"2013","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0040","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.radonc.2016.03.020","article-title":"Image guided adaptive brachytherapy with combined intracavitary and interstitial technique improves the therapeutic ratio in locally advanced cervical cancer: Analysis from the retroEMBRACE study","volume":"120","author":"Fokdal","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0045","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.radonc.2007.04.012","article-title":"Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer","volume":"83","author":"P\u00f6tter","year":"2007","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0050","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.radonc.2011.07.012","article-title":"Clinical outcome of protocol based image (MRI) guided adaptive brachytherapy combined with 3D conformal radiotherapy with or without chemotherapy in patients with locally advanced cervical cancer","volume":"100","author":"P\u00f6tter","year":"2011","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0055","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.radonc.2016.03.011","article-title":"Image guided brachytherapy in locally advanced cervical cancer: Improved pelvic control and survival in RetroEMBRACE, a multicenter cohort study","volume":"120","author":"Sturdza","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0060","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1016\/j.ijrobp.2017.06.010","article-title":"Magnetic resonance image guided adaptive brachytherapy in locally advanced cervical cancer: an experience from a tertiary cancer center in a low and middle income countries setting","volume":"99","author":"Mahantshetty","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0065","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.3109\/0284186X.2013.818251","article-title":"Magnetic resonance imaging for assessment of parametrial tumour spread and regression patterns in adaptive cervix cancer radiotherapy","volume":"52","author":"Schmid","year":"2013","journal-title":"Acta Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0070","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.radonc.2016.05.029","article-title":"A volumetric analysis of GTV D and CTV HR as defined by the GEC ESTRO recommendations in FIGO stage IIB and IIIB cervical cancer patients treated with IGABT in a prospective multicentric trial (EMBRACE)","volume":"120","author":"Jastaniyah","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0075","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.radonc.2016.05.014","article-title":"Effect of tumor dose, volume and overall treatment time on local control after radiochemotherapy including MRI guided brachytherapy of locally advanced cervical cancer","volume":"120","author":"Tanderup","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0080","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.radonc.2004.12.015","article-title":"Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group(I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV","volume":"74","author":"Haie-Meder","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/jicru_ndw027","article-title":"International Commission on Radiation Units and Measurements. Prescribing, recording, and reporting brachytherapy for cancer of the cervix: issue 89 of ICRU report","volume":"13","author":"Potter","year":"2013","journal-title":"J ICRU Bethesda"},{"key":"10.1016\/j.radonc.2019.08.004_b0090","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.radonc.2005.11.014","article-title":"Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose\u2013volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology","volume":"78","author":"P\u00f6tter","year":"2006","journal-title":"Radiother Oncol"},{"issue":"9","key":"10.1016\/j.radonc.2019.08.004_b0095","first-page":"48","article-title":"The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies","volume":"11","author":"P\u00f6tter","year":"2018","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0100","unstructured":"Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0, (http:\/\/ctep.cancer.gov) DCTD, NCI, NIH, DHHS, 2003 Mar 31, 2006 Aug 9; 1\u201371."},{"key":"10.1016\/j.radonc.2019.08.004_b0105","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ygyno.2016.10.020","article-title":"Long term results from a prospective database on high dose rate (HDR) interstitial brachytherapy for primary cervical carcinoma","volume":"144","author":"Fallon","year":"2017","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0110","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.brachy.2008.12.002","article-title":"High-dose-rate interstitial brachytherapy for previously untreated cervical carcinoma","volume":"8","author":"Isohashi","year":"2009","journal-title":"Brachytherapy"},{"issue":"19","key":"10.1016\/j.radonc.2019.08.004_b0115","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.gore.2016.11.007","article-title":"Clinical trials in low and middle-income countries-successes and challenges","volume":"1","author":"Grover","year":"2017","journal-title":"Gynecol Oncol Rep"},{"key":"10.1016\/j.radonc.2019.08.004_b0120","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.ijrobp.2012.05.033","article-title":"Outcomes of high-dose-rate interstitial brachytherapy in the treatment of locally advanced cervical cancer: long-term results","volume":"85","author":"Pinn-Bingham","year":"2013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijrobp.2018.05.080","article-title":"A prospective comparison of computed tomography with transrectal ultrasonography assistance and magnetic resonance imaging-based target-volume definition during image guided adaptive brachytherapy for cervical cancers","author":"Mahantshetty","year":"2018","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0130","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.radonc.2016.01.021","article-title":"Transrectal ultrasound for image-guided adaptive brachytherapy in cervix cancer \u2013 an alternative to MRI for target definition?","volume":"120","author":"Schmid","year":"2016","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2019.08.004_b0135","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1016\/j.brachy.2018.04.006","article-title":"Real-time Doppler ultrasound to identify vessels and guide needle placement for gynecologic interstitial brachytherapy","volume":"17","author":"Sethi","year":"2018","journal-title":"Brachytherapy"},{"key":"10.1016\/j.radonc.2019.08.004_b0140","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0360-3016(85)90163-4","article-title":"Combination of external beam irradiation and multiplesite perineal applicator (MUPIT) for treatment of locally advanced or recurrent prostatic, anorectal, and gynecologic malignancies","volume":"11","author":"Martinez","year":"1985","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2019.08.004_b0145","doi-asserted-by":"crossref","first-page":"S21","DOI":"10.1016\/j.brachy.2016.04.010","article-title":"Image guided brachytherapy in cervical cancer: a comparison between intracavitary and combined intracavitary\/interstitial brachytherapy in regard to doses to HR CTV, OARs and late morbidity-early results from the embrace study in 999 patients","volume":"15","author":"Fortin","year":"2016","journal-title":"Brachytherapy"},{"key":"10.1016\/j.radonc.2019.08.004_b0150","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.brachy.2018.05.009","article-title":"Combined intracavitary and interstitial brachytherapy of cervical cancer using the novel hybrid applicator Venezia: clinical feasibility and initial results","volume":"17","author":"Walter","year":"2018","journal-title":"Brachytherapy"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814019330439?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814019330439?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T05:09:18Z","timestamp":1759122558000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814019330439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":30,"alternative-id":["S0167814019330439"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2019.08.004","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vienna-II ring applicator for distal parametrial\/pelvic wall disease in cervical cancer brachytherapy: An experience from two institutions: Clinical feasibility and outcome","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2019.08.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}