{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T12:58:14Z","timestamp":1768913894332,"version":"3.49.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.radonc.2021.02.030","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T01:56:22Z","timestamp":1614563782000},"page":"285-292","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["End to end intussusception anastomosis decreases the risk of anastomotic leakage after neoadjvant chemoradiation and McKeown oesophagectomy"],"prefix":"10.1016","volume":"158","author":[{"given":"Yutian","family":"Lai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoxiao","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2016-3398","authenticated-orcid":false,"given":"Kun","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojuan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongmei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5437-3457","authenticated-orcid":false,"given":"Yang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2021.02.030_b0005","first-page":"394","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray","year":"2018","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.radonc.2021.02.030_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.21147\/j.issn.1000-9604.2018.01.01","article-title":"Cancer incidence and mortality in China, 2014","volume":"30","author":"Chen","year":"2018","journal-title":"Chin J Cancer Res"},{"key":"10.1016\/j.radonc.2021.02.030_b0015","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1016\/S1470-2045(14)70419-X","article-title":"Assessment of the quality of surgery within randomised controlled trials for the treatment of gastro-oesophageal cancer: a systematic review","volume":"16","author":"Markar","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0020","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/S1470-2045(15)00040-6","article-title":"Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial","volume":"16","author":"Shapiro","year":"2015","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0025","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1002\/bjs.9792","article-title":"Determinants of improved survival after oesophagectomy for cancer","volume":"102","author":"Talsma","year":"2015","journal-title":"Br J Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0030","doi-asserted-by":"crossref","first-page":"2074","DOI":"10.1056\/NEJMoa1112088","article-title":"Preoperative chemoradiotherapy for esophageal or junctional cancer","volume":"366","author":"van Hagen","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2021.02.030_b0035","first-page":"76","article-title":"Radiation dose mapping and anastomotic complications after trimodality therapy for esophageal cancers","volume":"15","author":"Bang","year":"2019","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0040","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1016\/j.athoracsur.2013.07.119","article-title":"Predictors of anastomotic leak after esophagectomy: an analysis of the society of thoracic surgeons general thoracic database","volume":"96","author":"Kassis","year":"2013","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0045","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S1010-7940(03)00274-4","article-title":"Effects of preoperative chemoradiotherapy on postsurgical morbidity and mortality in cT3-4 +\/- cM1lymph cancer of the oesophagus and gastro-oesophageal junction","volume":"24","author":"Hagry","year":"2003","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0050","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.jtcvs.2006.05.015","article-title":"Neoadjuvant chemoradiation may increase the risk of respiratory complications and sepsis after transthoracic esophagectomy","volume":"132","author":"Reynolds","year":"2006","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0055","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1200\/JCO.2005.05.0658","article-title":"Surgical mortality in patients with esophageal cancer: development and validation of a simple risk score","volume":"24","author":"Steyerberg","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0060","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/JTO.0000000000000100","article-title":"Influence of preoperative radiation field on postoperative leak rates in esophageal cancer patients after trimodality therapy","volume":"9","author":"Juloori","year":"2014","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0065","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1016\/j.athoracsur.2016.08.027","article-title":"Radiation to the gastric fundus increases the risk of anastomotic leakage after esophagectomy","volume":"102","author":"Goense","year":"2016","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0070","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/s13014-015-0361-4","article-title":"Radiation dose does not influence anastomotic complications in patients with esophageal cancer treated with neoadjuvant chemoradiation and transhiatal esophagectomy","volume":"10","author":"Ko\u00ebter","year":"2015","journal-title":"Radiat Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0075","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.ijrobp.2016.11.054","article-title":"Influence of the extent and dose of radiation on complications after neoadjuvant chemoradiation and subsequent esophagectomy with gastric tube reconstruction with a cervical anastomosis","volume":"97","author":"Ko\u00ebter","year":"2017","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.02.030_b0080","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1097\/SLA.0b013e31822676a9","article-title":"End-to-end versus end-to-side esophagogastrostomy after esophageal cancer resection: a prospective randomized study","volume":"254","author":"Nederlof","year":"2011","journal-title":"Ann Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0085","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1148\/radiol.14140410","article-title":"Calcification of arteries supplying the gastric tube: a new risk factor for anastomotic leakage after esophageal surgery","volume":"274","author":"van Rossum","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.radonc.2021.02.030_b0090","doi-asserted-by":"crossref","first-page":"4062","DOI":"10.1245\/s10434-019-07630-2","article-title":"End-to-end versus end-to-side hand-sewn anastomosis for minimally invasive mckeown esophagectomy","volume":"26","author":"Mao","year":"2019","journal-title":"Ann Surg Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0095","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/dote.12171","article-title":"Esophageal anastomosis","volume":"28","author":"Yuan","year":"2015","journal-title":"Dis Esophagus"},{"key":"10.1016\/j.radonc.2021.02.030_b0100","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","author":"Dindo","year":"2004","journal-title":"Ann Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0105","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jtho.2016.10.016","article-title":"Cancer of the esophagus and esophagogastric junction: an eighth edition staging primer","volume":"12","author":"Rice","year":"2017","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.radonc.2021.02.030_b0110","unstructured":"Tang HT, Berlin J, Branton P, Burgart LJ, Carter DK, Compton CC, et al. Protocol for the examination of specimens from patients with arcinoma of the stomach. In: CANCER PROTOCOL. College of American Pathologists, Http:\/\/www.cap.org\/ShowProperty?nodePath=\/UCMCon\/Contribution%20Folders\/WebContent\/pdf\/cp-stomach14-protocol.pdf; 2014 [accessed 11 June 2014]."},{"key":"10.1016\/j.radonc.2021.02.030_b0115","doi-asserted-by":"crossref","first-page":"e513","DOI":"10.1016\/j.ijrobp.2011.05.071","article-title":"Anastomotic complications after Ivor Lewis esophagectomy in patients treated with neoadjuvant chemoradiation are related to radiation dose to the gastric fundus","volume":"82","author":"Vande Walle","year":"2012","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.02.030_b0120","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1056\/NEJMoa022343","article-title":"Extended transthoracic resection compared with limited transhiatal resection for adenocarcinoma of the esophagus","volume":"347","author":"Hulscher","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2021.02.030_b0125","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1016\/j.athoracsur.2011.05.121","article-title":"Morbidity and mortality after esophagectomy following neoadjuvant chemoradiation","volume":"92","author":"Merritt","year":"2011","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0130","doi-asserted-by":"crossref","unstructured":"Gronnier C, Tr\u00e9chot B, Duhamel A, Mabrut JY, Bail JP, Carrere N, et al. Impact of neoadjuvant chemoradiotherapy on postoperative outcomes after esophageal cancer resection: results of a European multicenter study. Ann Surg 2014;260:764\u201370; discussion 70\u20131. https:\/\/doi.org\/10.1097\/sla.0000000000000955.","DOI":"10.1097\/SLA.0000000000000955"},{"key":"10.1016\/j.radonc.2021.02.030_b0135","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1002\/bjs.9418","article-title":"Meta-analysis of postoperative morbidity and perioperative mortality in patients receiving neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal and gastro-oesophageal junctional cancers","volume":"101","author":"Kumagai","year":"2014","journal-title":"Br J Surg"},{"key":"10.1016\/j.radonc.2021.02.030_b0140","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.athoracsur.2015.09.094","article-title":"Embedded three-layer esophagogastric anastomosis reduces morbidity and improves short-term outcomes after esophagectomy for cancer","volume":"101","author":"Sun","year":"2016","journal-title":"Ann Thorac Surg"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016781402106093X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016781402106093X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T05:17:15Z","timestamp":1759123035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016781402106093X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":28,"alternative-id":["S016781402106093X"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2021.02.030","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"End to end intussusception anastomosis decreases the risk of anastomotic leakage after neoadjvant chemoradiation and McKeown oesophagectomy","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2021.02.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}