{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:25:08Z","timestamp":1790645108478,"version":"4.1.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.radonc.2021.04.026","type":"journal-article","created":{"date-parts":[[2021,5,10]],"date-time":"2021-05-10T22:30:41Z","timestamp":1620685841000},"page":"140-147","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"special_numbering":"C","title":["Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: A GORTEC internationally-reviewed HNCIG-endorsed consensus"],"prefix":"10.1016","volume":"160","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5574-8559","authenticated-orcid":false,"given":"Florent","family":"Carsuzaa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Lapeyre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Gregoire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5364-9979","authenticated-orcid":false,"given":"Philippe","family":"Maingon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5512-4161","authenticated-orcid":false,"given":"Arnaud","family":"Beddok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre-Yves","family":"Marcy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Salleron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Coutte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Severine","family":"Racadot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoann","family":"Pointreau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Graff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5497-2831","authenticated-orcid":false,"given":"Beth","family":"Beadle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Benezery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1570-4487","authenticated-orcid":false,"given":"Julian","family":"Biau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7156-9750","authenticated-orcid":false,"given":"Valentin","family":"Calugaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel","family":"Castelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1648-1473","authenticated-orcid":false,"given":"Melvin","family":"Chua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessia","family":"Di Rito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Dore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2747-165X","authenticated-orcid":false,"given":"Pirus","family":"Ghadjar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florence","family":"Huguet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5780-6687","authenticated-orcid":false,"given":"Pauline","family":"Jardel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorgen","family":"Johansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall","family":"Kimple","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2064-8379","authenticated-orcid":false,"given":"Marco","family":"Krengli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarbani","family":"Laskar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lachlan","family":"Mcdowell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Nichols","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silke","family":"tribius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1675-7281","authenticated-orcid":false,"given":"Izaskun","family":"Valduvieco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaosu","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Liem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1260-1762","authenticated-orcid":false,"given":"Antoine","family":"Moya-Plana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ida","family":"D'onofrio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Upendra","family":"Parvathaneni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2499-3516","authenticated-orcid":false,"given":"Vinita","family":"Takiar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester","family":"Orlandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Psyrri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Shenouda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3943-7480","authenticated-orcid":false,"given":"David","family":"Sher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conor","family":"Steuer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Shan Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yungan","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Thomson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1251-7862","authenticated-orcid":false,"given":"Mu-Hung","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noemie","family":"Vulquin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Gorphe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisham","family":"Mehanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0779-7476","authenticated-orcid":false,"given":"Sue S.","family":"Yom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Bourhis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4755-496X","authenticated-orcid":false,"given":"Juliette","family":"Thariat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2021.04.026_b0005","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1097\/00005537-200309000-00008","article-title":"Advances in head and neck reconstruction","volume":"113","author":"Urken","year":"2003","journal-title":"Laryngoscope"},{"key":"10.1016\/j.radonc.2021.04.026_b0010","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.bulcan.2020.04.011","article-title":"Ten years of advances in head and neck surgery, how does this influence postoperative radiotherapy?","volume":"107","author":"Thariat","year":"2020","journal-title":"Bull Cancer (Paris)"},{"key":"10.1016\/j.radonc.2021.04.026_b0015","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/0007-1226(84)90049-3","article-title":"A classification of fascio-cutaneous flaps according to their patterns of vascularisation","volume":"37","author":"Cormack","year":"1984","journal-title":"Br J Plast Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0020","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1007\/BF01670524","article-title":"Progress in flap surgery: greater anatomical understanding and increased sophistication in application","volume":"14","author":"Lamberty","year":"1990","journal-title":"World J Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0025","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.suronc.2017.11.005","article-title":"Long-term quality of life and psycho-social outcomes after oropharyngeal cancer surgery and radial forearm free-flap reconstruction: a GETTEC prospective multicentric study","volume":"27","author":"Bozec","year":"2018","journal-title":"Surg Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0030","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.radonc.2017.10.016","volume":"126","author":"Gr\u00e9goire","year":"2018","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0035","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S0360-3016(02)03940-8","article-title":"Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer","volume":"55","author":"Chao","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.04.026_b0040","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.radonc.2006.03.009","article-title":"Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck","volume":"79","author":"Gr\u00e9goire","year":"2006","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0045","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.radonc.2003.09.011","article-title":"CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC, RTOG consensus guidelines","volume":"69","author":"Gr\u00e9goire","year":"2003","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0050","doi-asserted-by":"crossref","first-page":"3916","DOI":"10.1002\/hed.25928","article-title":"Patterns of local recurrence after curative resection and reconstruction for oropharyngeal and oral cancers: implications for postoperative radiotherapy target volumes","volume":"41","author":"Cho","year":"2019","journal-title":"Head Neck"},{"key":"10.1016\/j.radonc.2021.04.026_b0055","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.oraloncology.2018.08.011","article-title":"Target delineation for postoperative treatment of head and neck cancer","volume":"86","author":"Evans","year":"2018","journal-title":"Oral Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0060","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/hed.20279","article-title":"Defining risk levels in locally advanced head and neck cancers: a comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)","volume":"27","author":"Bernier","year":"2005","journal-title":"Head Neck"},{"key":"10.1016\/j.radonc.2021.04.026_b0065","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1056\/NEJMoa032641","article-title":"Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer","volume":"350","author":"Bernier","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2021.04.026_b0070","first-page":"649","article-title":"Impact of reconstructive or minimal invasive surgery on the assessment of current definitions of postoperative clinical target volume for head and neck cancers","volume":"24","author":"Racadot","year":"2020","journal-title":"Cancer Radiother J Soc Francaise Radiother Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0075","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.radonc.2020.08.025","article-title":"Flap delineation guidelines in postoperative head and neck radiation therapy for head and neck cancers","volume":"151","author":"Le Guevelou","year":"2020","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0080","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1055\/s-0040-1709493","article-title":"Analysis of speech and functional outcomes in tongue reconstruction after hemiglossectomy","volume":"36","author":"Yi","year":"2020","journal-title":"J Reconstr Microsurg"},{"key":"10.1016\/j.radonc.2021.04.026_b0085","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.3109\/00016489.2014.913809","article-title":"Long-term functional outcomes and quality of life after oncologic surgery and microvascular reconstruction in patients with oral or oropharyngeal cancer","volume":"134","author":"Pierre","year":"2014","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"10.1016\/j.radonc.2021.04.026_b0090","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1177\/0194599813498063","article-title":"Flap selection and functional outcomes in total glossectomy with laryngeal preservation","volume":"149","author":"Rihani","year":"2013","journal-title":"Otolaryngol-Head Neck Surg Off J Am Acad Otolaryngol-Head Neck Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0095","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1080\/00016480802369260","article-title":"Radical ablative surgery and radial forearm free flap (RFFF) reconstruction for patients with oral or oropharyngeal cancer: postoperative outcomes and oncologic and functional results","volume":"129","author":"Bozec","year":"2009","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"10.1016\/j.radonc.2021.04.026_b0100","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1097\/MLG.0b013e3181644abd","article-title":"Free-flap head and neck reconstruction and quality of life: a 2-year prospective study","volume":"118","author":"Bozec","year":"2008","journal-title":"Laryngoscope"},{"key":"10.1016\/j.radonc.2021.04.026_b0105","first-page":"401","article-title":"Quality of life after oral and oropharyngeal reconstruction with a radial forearm free flap: prospective study","volume":"38","author":"Bozec","year":"2009","journal-title":"J Otolaryngol - Head Neck Surg J Oto-Rhino-Laryngol Chir Cervico-Faciale"},{"key":"10.1016\/j.radonc.2021.04.026_b0110","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1097\/SCS.0000000000000443","article-title":"A comparison between the pectoralis major myocutaneous flap and the free anterolateral thigh perforator flap for reconstruction in head and neck cancer patients: assessment of the quality of life","volume":"25","author":"Zhang","year":"2014","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0115","first-page":"2553","article-title":"Factors influencing neck and shoulder function after oral oncology treatment: a five-year prospective cohort study in 113 patients","volume":"27","author":"van Hinte","year":"2019","journal-title":"Support Care Cancer Off J Multinatl Assoc Support Care Cancer"},{"key":"10.1016\/j.radonc.2021.04.026_b0120","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.joms.2011.04.014","article-title":"Radiotherapy deteriorates postoperative functional outcome after partial glossectomy with free flap reconstruction","volume":"70","author":"Shin","year":"2012","journal-title":"J Oral Maxillofac Surg Off J Am Assoc Oral Maxillofac Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0125","first-page":"851","article-title":"Postoperative radiotherapy after flap reconstructive surgery in patients with head and neck cancer: a retrospective monocentric study with flap delineation to assess toxicity and relapse","volume":"24","author":"G\u00e9rard","year":"2020","journal-title":"Cancer Radiother J Soc Francaise Radiother Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0130","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1016\/j.bjps.2016.02.001","article-title":"Identification of independent risk factors for flap failure: a retrospective analysis of 1530 free flaps for breast, head and neck and extremity reconstruction","volume":"69","author":"Las","year":"2016","journal-title":"J Plast Reconstr Aesthetic Surg JPRAS"},{"key":"10.1016\/j.radonc.2021.04.026_b0135","doi-asserted-by":"crossref","unstructured":"Ooishi M, Motegi A, Kawashima M, Arahira S, Zenda S, Nakamura N, et al. Patterns of failure after postoperative intensity-modulated radiotherapy for locally advanced and recurrent head and neck cancer. Jpn J Clin Oncol 2016;46:919\u201327. https:\/\/doi.org\/10.1093\/jjco\/hyw095.","DOI":"10.1093\/jjco\/hyw095"},{"key":"10.1016\/j.radonc.2021.04.026_b0140","doi-asserted-by":"crossref","first-page":"e1253","DOI":"10.1097\/GOX.0000000000001253","article-title":"Improved head and neck free flap outcome-effects of a treatment protocol adjustment from pre- to postoperative radiotherapy","volume":"5","author":"Halle","year":"2017","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"10.1016\/j.radonc.2021.04.026_b0145","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1001\/archotol.130.11.1308","article-title":"Radiation therapy does not impact local complication rates after free flap reconstruction for head and neck cancer","volume":"130","author":"Choi","year":"2004","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0150","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1136\/bmj.311.7001.376","article-title":"Consensus methods for medical and health services research","volume":"311","author":"Jones","year":"1995","journal-title":"BMJ"},{"key":"10.1016\/j.radonc.2021.04.026_b0155","unstructured":"French Haute autorit\u00e9 de sant\u00e9. Elaboration de recommandation de bonne pratique - Recommandations par consensus formalis\u00e9 2010."},{"key":"10.1016\/j.radonc.2021.04.026_b0160","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1080\/00016480802163366","article-title":"Comparison of radiotherapy strategies for locally advanced hypopharyngeal cancer after resection and ileocolic flap reconstruction","volume":"129","author":"Tai","year":"2009","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"10.1016\/j.radonc.2021.04.026_b0165","first-page":"742","article-title":"The effect of adjuvant radiotherapy on radial forearm free flap volume after soft palate reconstruction in 13 patients","volume":"43","author":"Haymerle","year":"2018","journal-title":"Clin Otolaryngol Off J ENT-UK Off J Neth Soc Oto-Rhino-Laryngol Cervico-Facial Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0170","doi-asserted-by":"crossref","unstructured":"Yamazaki M, Suzuki T, Hiraga C, Yoshida Y, Baba A, Saitou H, et al. Effect of postoperative radiotherapy for free flap volume changing after tongue reconstruction. Oral Radiol 2020. https:\/\/doi.org\/10.1007\/s11282-020-00489-0.","DOI":"10.1007\/s11282-020-00489-0"},{"key":"10.1016\/j.radonc.2021.04.026_b0175","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.1365-2273.2004.00812.x","article-title":"Quality of life following resection, free flap reconstruction and postoperative external beam radiotherapy for squamous cell carcinoma of the base of tongue","volume":"29","author":"Winter","year":"2004","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"10.1016\/j.radonc.2021.04.026_b0180","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1080\/00016480510027457","article-title":"Ileocolic free flap reconstruction, concomitant chemotherapy and radiotherapy and assessment of speech and swallowing function during management of advanced cancer of the larynx and hypopharynx: preliminary report","volume":"125","author":"Leu","year":"2005","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"10.1016\/j.radonc.2021.04.026_b0185","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/hed.21471","article-title":"Functional and psychological evaluation after flap reconstruction plus radiotherapy in oral cancer","volume":"33","author":"Airoldi","year":"2011","journal-title":"Head Neck"},{"key":"10.1016\/j.radonc.2021.04.026_b0190","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1002\/lary.22509","article-title":"Volumetric changes of the anterolateral thigh free flap following adjuvant radiotherapy in total parotidectomy reconstruction","volume":"122","author":"Higgins","year":"2012","journal-title":"Laryngoscope"},{"key":"10.1016\/j.radonc.2021.04.026_b0195","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.jcms.2016.04.031","article-title":"Microvascular reconstruction of the tongue using a free anterolateral thigh flap: three-dimensional evaluation of volume loss after radiotherapy","volume":"44","author":"Tarsitano","year":"2016","journal-title":"J Cranio-Maxillo-Fac Surg Off Publ Eur Assoc Cranio-Maxillo-Fac Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0200","first-page":"959","article-title":"Olfactory and gustatory functions after free flap reconstruction and radiotherapy for oral and pharyngeal cancer: a prospective follow-up study","volume":"275","author":"Lilja","year":"2018","journal-title":"Eur Arch Oto-Rhino-Laryngol Off J Eur Fed Oto-Rhino-Laryngol Soc EUFOS Affil Ger Soc Oto-Rhino-Laryngol - Head Neck Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0205","first-page":"666","article-title":"Microscopic extensions of head and neck squamous cell carcinomas: impact for clinical target volume definition","volume":"18","author":"Fleury","year":"2014","journal-title":"Cancer Radiother J Soc Francaise Radiother Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0210","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.radonc.2015.04.025","article-title":"Clipping of tumour resection margins allows accurate target volume delineation in head and neck cancer adjuvant radiation therapy","volume":"116","author":"Bittermann","year":"2015","journal-title":"Radiother Oncol J Eur Soc Ther Radiol Oncol"},{"key":"10.1016\/j.radonc.2021.04.026_b0215","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.jcms.2015.04.005","article-title":"The validity of surgical clips as radiographic markers for the tumour resection cavity in head and neck cancer treatment","volume":"43","author":"Bittermann","year":"2015","journal-title":"J Cranio-Maxillo-Fac Surg Off Publ Eur Assoc Cranio-Maxillo-Fac Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0220","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.jcms.2015.02.021","article-title":"Marking of tumor resection borders for improved radiation planning facilitates reduction of radiation dose to free flap reconstruction in head and neck cancer surgery","volume":"43","author":"Bittermann","year":"2015","journal-title":"J Cranio-Maxillo-Fac Surg Off Publ Eur Assoc Cranio-Maxillo-Fac Surg"},{"key":"10.1016\/j.radonc.2021.04.026_b0225","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/hed.2880130308","article-title":"Irradiation and free tissue transfer in head and neck cancer","volume":"13","author":"Jose","year":"1991","journal-title":"Head Neck"},{"key":"10.1016\/j.radonc.2021.04.026_b0230","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.anl.2004.03.003","article-title":"Use of free flaps for reconstruction in head and neck surgery: a retrospective study of 182 cases","volume":"31","author":"Nakamizo","year":"2004","journal-title":"Auris Nasus Larynx"},{"key":"10.1016\/j.radonc.2021.04.026_b0235","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1002\/hed.26490","article-title":"Systematic review of postoperative therapy for resected squamous cell carcinoma of the head and neck: Executive summary of the American Radium Society appropriate use criteria","volume":"43","author":"Margalit","year":"2021","journal-title":"Head Neck"},{"key":"10.1016\/j.radonc.2021.04.026_b0240","first-page":"1908","article-title":"Impact of HPV-associated p16-expression and other clinical factors on therapeutic decision-making in patients with oropharyngeal cancer: a GETTEC multicentric study","volume":"44","author":"Culi\u00e9","year":"2018","journal-title":"Eur J Surg Oncol J Eur Soc Surg Oncol Br Assoc Surg Oncol"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814021062265?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814021062265?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T05:15:49Z","timestamp":1759122949000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814021062265"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":48,"alternative-id":["S0167814021062265"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2021.04.026","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Recommendations for postoperative radiotherapy in head & neck squamous cell carcinoma in the presence of flaps: A GORTEC internationally-reviewed HNCIG-endorsed consensus","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2021.04.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}