{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:03:20Z","timestamp":1759190600708,"version":"3.44.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.radonc.2021.07.008","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T01:20:22Z","timestamp":1626312022000},"page":"156-161","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Extreme weekly locoregional hypofractionated radiation in elderly women with non-metastatic breast cancer"],"prefix":"10.1016","volume":"162","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4982-8696","authenticated-orcid":false,"given":"Fadoua","family":"Rais","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James Man Git","family":"Tsui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Daianska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mame Daro","family":"Faye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"David","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie","family":"Panet-Raymond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melissa","family":"Azoulay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asma","family":"Saidi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9341-1735","authenticated-orcid":false,"given":"Tarek","family":"Hijal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2021.07.008_b0005","doi-asserted-by":"crossref","unstructured":"Breast cancer in the elderly\u2014Should it be treated differently? Rep Pract Oncol Radiother 2013;18: 26\u201333.","DOI":"10.1016\/j.rpor.2012.05.005"},{"key":"10.1016\/j.radonc.2021.07.008_b0010","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ijrobp.2004.04.059","article-title":"Long-term results of adjuvant hypofractionated radiotherapy for breast cancer in elderly patients","volume":"61","author":"Ortholan","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.07.008_b0015","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1002\/(SICI)1097-0142(20000515)88:10<2260::AID-CNCR9>3.0.CO;2-M","article-title":"The effects of radiation therapy on quality of life of women with breast carcinoma","volume":"88","author":"Whelan","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.radonc.2021.07.008_b0020","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1002\/1097-0142(19941001)74:7+<2208::AID-CNCR2820741737>3.0.CO;2-#","article-title":"Representation of older patients in cancer treatment trials","volume":"74","author":"Trimble","year":"1994","journal-title":"Cancer"},{"key":"10.1016\/j.radonc.2021.07.008_b0025","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/0360-3016(95)00060-C","article-title":"Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)","volume":"31","author":"Cox","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.07.008_b0030","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/0360-3016(95)90159-0","volume":"31","author":"LENT-SOMA scales for all anatomic sites","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.07.008_b0035","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1023\/A:1011136326943","article-title":"Radiotherapy after breast-conserving surgery in small breast carcinoma: Longterm results of a randomized trial","volume":"12","author":"Veronesi","year":"2001","journal-title":"Ann Oncol"},{"key":"10.1016\/j.radonc.2021.07.008_b0040","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1023\/A:1006064608360","article-title":"It is possible to omit postoperative irradiation in a highly selected group of elderly breast cancer patients","volume":"50","author":"Gruenberger","year":"1998","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.radonc.2021.07.008_b0045","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0959-8049(03)00149-7","article-title":"Quality of life in breast cancer patients aged over 70 years, participating in the EORTC 10850 randomised clinical trial","volume":"39","author":"de Haes","year":"2003","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.radonc.2021.07.008_b0050","doi-asserted-by":"crossref","first-page":"3580","DOI":"10.1200\/JCO.2003.02.046","article-title":"Undertreatment strongly decreases prognosis of breast cancer in elderly women","volume":"21","author":"Bouchardy","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2021.07.008_b0055","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ijrobp.2008.11.005","article-title":"Breast conserving treatment in the elderly: long-term results of adjuvant hypofractionated and normofractionated radiotherapy","volume":"75","author":"Kirova","year":"2009","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.07.008_b0060","unstructured":"Kirova, Y.M., et al., Breast-conserving treatment in the elderly: long-term results of adjuvant hypofractionated and normofractionated radiotherapy. Int J Radiat."},{"key":"10.1016\/j.radonc.2021.07.008_b0065","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.critrevonc.2008.09.011","article-title":"Breast conserving treatment (BCT) for stage I-II breast cancer in elderly women: analysis of 927 cases","volume":"71","author":"Cutuli","year":"2009","journal-title":"Crit Rev Oncol Hematol"},{"key":"10.1016\/j.radonc.2021.07.008_b0070","doi-asserted-by":"crossref","unstructured":"Brunt, A.M., et al. A 5-fraction regimen of adjuvant radiotherapy for women with early breast cancer: first analysis of the randomised UK FAST trial (ISRCTN62488883, CRUKE\/04\/015). EJC Supplements. Presidential sessions late breaking and best of ECCO 15-ESMO 34 Abstracts, 2009. 7(3): p.2.","DOI":"10.1016\/S1359-6349(09)72026-9"},{"key":"10.1016\/j.radonc.2021.07.008_b0075","article-title":"Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial","author":"Brunt","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.radonc.2021.07.008_b0080","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1016\/S0140-6736(05)67887-7","article-title":"Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials","volume":"366","author":"Clarke","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.radonc.2021.07.008_b0085","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1016\/S0140-6736(11)61629-2","article-title":"Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials","volume":"378","author":"Darby","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.radonc.2021.07.008_b0090","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0360-3016(92)90895-O","article-title":"Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer","volume":"23","author":"Pierce","year":"1992","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2021.07.008_b0095","unstructured":"Haviland JS, Mannino M, Griffin C, Porta N, Sydenham MA, Bliss JM, Yarnold JR on behalf of the START Trialists\u2019 Group et al. Late normal tissue effects in the arm and shoulder following lymphatic radiotherapy: Results from the UK START (Standardisation of Breast Radiotherapy) trials. Radiother Oncol. 2017. pii: S0167-8140(17)32687-7."},{"key":"10.1016\/j.radonc.2021.07.008_b0100","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.breast.2010.04.004","article-title":"The impact of the loco-regional treatment in elderly breast cancer patients: hypo-fractionated exclusive radiotherapy, single institution long-term results","volume":"19","author":"Chargari","year":"2010","journal-title":"The Breast"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814021066457?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814021066457?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T05:19:31Z","timestamp":1759123171000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814021066457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":20,"alternative-id":["S0167814021066457"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2021.07.008","relation":{},"ISSN":["0167-8140"],"issn-type":[{"type":"print","value":"0167-8140"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Extreme weekly locoregional hypofractionated radiation in elderly women with non-metastatic breast cancer","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2021.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}