{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:56:27Z","timestamp":1787316987076,"version":"build-2736575974"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P41EB022544"],"award-info":[{"award-number":["P41EB022544"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA165221"],"award-info":[{"award-number":["R01CA165221"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01EB033582"],"award-info":[{"award-number":["R01EB033582"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["T32EB013180"],"award-info":[{"award-number":["T32EB013180"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.radonc.2024.110186","type":"journal-article","created":{"date-parts":[[2024,2,25]],"date-time":"2024-02-25T17:53:22Z","timestamp":1708883602000},"page":"110186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["The role of 18F-FDG PET in minimizing variability in gross tumor volume delineation of soft tissue sarcomas"],"prefix":"10.1016","volume":"194","author":[{"given":"Elie","family":"Najem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8669-1003","authenticated-orcid":false,"given":"Thibault","family":"Marin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita Maria","family":"Lahoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5512-4161","authenticated-orcid":false,"given":"Arnaud","family":"Beddok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6306-8008","authenticated-orcid":false,"given":"Laura","family":"Rozenblum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0517-0952","authenticated-orcid":false,"given":"Fangxu","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Moteabbed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0386-0578","authenticated-orcid":false,"given":"Ruth","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4514-2016","authenticated-orcid":false,"given":"Xiaofeng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonghye","family":"Woo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen John","family":"Lostetter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdallah","family":"Lamane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen-Lin Evelyn","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"El Fakhri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2024.110186_b0005","first-page":"9","article-title":"Cancer statistics, 2012","volume":"64","author":"Siegal","year":"2014","journal-title":"CA: A Cancer J Clin"},{"key":"10.1016\/j.radonc.2024.110186_b0010","unstructured":"American Cancer Society. Cancer Facts & Figures 2023. Atlanta, Ga: American Cancer Society; 2023."},{"key":"10.1016\/j.radonc.2024.110186_b0015","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3949\/ccjm.89a.21078","article-title":"Soft tissue sarcoma: recognizing a rare disease","volume":"89","author":"Ardakani","year":"2022","journal-title":"Cleveland Clin J Med"},{"key":"10.1016\/j.radonc.2024.110186_b0020","article-title":"SELNET clinical practice guidelines for soft tissue sarcoma and GIST","volume":"1","author":"Blay","year":"2022","journal-title":"Cancer Treatment Rev"},{"key":"10.1016\/j.radonc.2024.110186_b0025","doi-asserted-by":"crossref","first-page":"e775","DOI":"10.1016\/j.ijrobp.2010.11.033","article-title":"Variation in the gross tumor volume and clinical target volume for preoperative radiotherapy of primary large high-grade soft tissue sarcoma of the extremity among RTOG sarcoma radiation oncologists","volume":"81","author":"Wang","year":"2011","journal-title":"Int J Radiat Oncol* Biol* Phys"},{"key":"10.1016\/j.radonc.2024.110186_b0030","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0360-3016(03)00090-7","article-title":"Image guidance for precise conformal radiotherapy","volume":"56","author":"Mackie","year":"2003","journal-title":"Int J Radiat Oncol* Biol* Phys"},{"key":"10.1016\/j.radonc.2024.110186_b0035","doi-asserted-by":"crossref","unstructured":"Yan D, Lockman D, Martinez A, Wong J, Brabbins D, Vicini F, et al. Computed tomography guided management of interfractional patient variation. In: Seminars in radiation oncology 2005 Jul 1, Vol. 15, No. 3. WB Saunders. p. 168\u201379.","DOI":"10.1016\/j.semradonc.2005.01.007"},{"key":"10.1016\/j.radonc.2024.110186_b0040","doi-asserted-by":"crossref","unstructured":"Mackie TR, Balog J, Ruchala K, Shepard D, Aldridge S, Fitchard E, et al. Tomotherapy. In: Seminars in Radiation Oncology 1999 Jan 1, Vol. 9, No. 1. WB Saunders. p. 108\u201317.","DOI":"10.1016\/S1053-4296(99)80058-7"},{"key":"10.1016\/j.radonc.2024.110186_b0045","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/j.ijrobp.2004.11.033","article-title":"Use of deformed intensity distributions for on-line modification of image-guided IMRT to account for interfractional anatomic changes","volume":"61","author":"Mohan","year":"2005","journal-title":"Int J Radiat Oncol* Biol* Phys"},{"key":"10.1016\/j.radonc.2024.110186_b0050","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s11864-003-0046-3","article-title":"Techniques to modulate radiotherapy toxicity and outcome in soft tissue sarcoma","volume":"4","author":"O\u2019Sullivan","year":"2003","journal-title":"Curr Treatment Options Oncol"},{"key":"10.1016\/j.radonc.2024.110186_b0055","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00066-003-0976-5","article-title":"The impact of gross tumor volume (GTV) and clinical target volume (CTV) definition on the total accuracy in radiotherapy","volume":"179","author":"Weiss","year":"2003","journal-title":"Strahlentherapie und Onkologie"},{"key":"10.1016\/j.radonc.2024.110186_b0060","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.canrad.2013.11.011","article-title":"Interobserver variability of clinical target volume delineation in soft-tissue sarcomas","volume":"18","author":"Genovesi","year":"2014","journal-title":"Cancer\/Radioth\u00e9rapie"},{"key":"10.1016\/j.radonc.2024.110186_b0065","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/j.ijrobp.2015.04.039","article-title":"Retroperitoneal sarcoma target volume and organ at risk contour delineation agreement among NRG sarcoma radiation oncologists","volume":"92","author":"Baldini","year":"2015","journal-title":"Int J Radiat Oncol* Biol* Phys"},{"key":"10.1016\/j.radonc.2024.110186_b0070","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.2967\/jnumed.114.141424","article-title":"Molecular imaging to plan radiotherapy and evaluate its efficacy","volume":"56","author":"Jeraj","year":"2015","journal-title":"J Nucl Med"},{"key":"10.1016\/j.radonc.2024.110186_b0075","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1148\/radiol.2331030660","article-title":"Tumor volume in pharyngolaryngeal squamous cell carcinoma: comparison at CT, MR imaging, and FDG PET and validation with surgical specimen","volume":"233","author":"Daisne","year":"2004","journal-title":"Radiology"},{"key":"10.1016\/j.radonc.2024.110186_b0080","doi-asserted-by":"crossref","first-page":"5471","DOI":"10.1088\/0031-9155\/60\/14\/5471","article-title":"A radiomics model from joint FDG-PET and MRI texture features for the prediction of lung metastases in soft-tissue sarcomas of the extremities","volume":"60","author":"Valli\u00e8res","year":"2015","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.radonc.2024.110186_b0085","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.prro.2021.04.005","article-title":"Radiation therapy for treatment of soft tissue sarcoma in adults: executive summary of an ASTRO clinical practice guideline","volume":"11","author":"Salerno","year":"2021","journal-title":"Pract Radiat Oncol"},{"key":"10.1016\/j.radonc.2024.110186_b0090","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.3109\/0284186X.2012.754989","article-title":"Clinical validation of atlas-based auto-segmentation of pelvic volumes and normal tissue in rectal tumors using auto-segmentation computed system","volume":"52","author":"Gambacorta","year":"2013","journal-title":"Acta Oncologica"},{"key":"10.1016\/j.radonc.2024.110186_b0095","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.radonc.2011.08.043","article-title":"Performance of an atlas-based autosegmentation software for delineation of target volumes for radiotherapy of breast and anorectal cancer","volume":"102","author":"Anders","year":"2012","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2024.110186_b0100","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1109\/42.363096","article-title":"Morphometric analysis of white matter lesions in MR images: method and validation","volume":"13","author":"Zijdenbos","year":"1994","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1016\/j.radonc.2024.110186_b0105","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.acra.2012.11.009","article-title":"Semiautomatic volumetric tumor segmentation for hepatocellular carcinoma: comparison between C-arm cone beam computed tomography and MRI","volume":"20","author":"Tacher","year":"2013","journal-title":"Acad Radiol"},{"key":"10.1016\/j.radonc.2024.110186_b0110","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.3109\/0284186X.2013.813069","article-title":"Automatic delineation for replanning in nasopharynx radiotherapy: what is the agreement among experts to be considered as benchmark?","volume":"52","author":"Mattiucci","year":"2013","journal-title":"Acta Oncologica"},{"key":"10.1016\/j.radonc.2024.110186_b0115","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1109\/TMI.2004.828354","article-title":"Simultaneous truth and performance level estimation (STAPLE): an algorithm for the validation of image segmentation","volume":"23","author":"Warfield","year":"2004","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1016\/j.radonc.2024.110186_b0120","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/j.ijrobp.2004.08.036","article-title":"Histologic assessment of peritumoral edema in soft tissue sarcoma","volume":"61","author":"White","year":"2005","journal-title":"Int J Radiat Oncol* Biol* Phys"},{"key":"10.1016\/j.radonc.2024.110186_b0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s41747-020-00200-2","article-title":"On the usage of average Hausdorff distance for segmentation performance assessment: hidden error when used for ranking","volume":"5","author":"Aydin","year":"2021","journal-title":"Eur Radiol Experimental"},{"key":"10.1016\/j.radonc.2024.110186_b0130","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1590\/0100-3984.2020.0028","article-title":"Manual versus semiautomatic segmentation of soft-tissue sarcomas on magnetic resonance imaging: evaluation of similarity and comparison of segmentation times","volume":"24","author":"Dionisio","year":"2021","journal-title":"Radiologia Brasileira"},{"key":"10.1016\/j.radonc.2024.110186_b0135","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.radonc.2021.09.034","article-title":"Deep learning-based GTV contouring modeling inter-and intra-observer variability in sarcomas","volume":"1","author":"Marin","year":"2022","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2024.110186_b0140","first-page":"33","article-title":"Gross tumour delineation on computed tomography and positron emission tomography-computed tomography in oesophageal cancer: a nationwide study","volume":"1","author":"Nowee","year":"2019","journal-title":"Clin Transl. Radiat. Oncol."},{"key":"10.1016\/j.radonc.2024.110186_b0145","first-page":"006","article-title":"Interobserver and intermodality variability in GTV delineation on simulation CT, FDG-PET, and MR images of head and neck cancer","volume":"1","author":"Anderson","year":"2014","journal-title":"Jacobs J Radiat Oncol"},{"key":"10.1016\/j.radonc.2024.110186_b0150","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.meddos.2007.08.003","article-title":"Variability of gross tumor volume delineation in head-and-neck cancer using PET\/CT fusion, Part II: the impact of a contouring protocol","volume":"34","author":"Berson","year":"2009","journal-title":"Medical Dosimetry"},{"key":"10.1016\/j.radonc.2024.110186_b0155","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.clon.2008.06.004","article-title":"Improving observer variability in target delineation for gastro-oesophageal cancer\u2014the role of 18Ffluoro-2-deoxy-D-glucose positron emission tomography\/computed tomography","volume":"20","author":"Vesprini","year":"2008","journal-title":"Clin Oncol"},{"key":"10.1016\/j.radonc.2024.110186_b0160","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.ijrobp.2008.11.055","article-title":"PET\/CT for radiotherapy treatment planning in patients with soft tissue sarcomas","volume":"75","author":"Karam","year":"2009","journal-title":"Int J Radiat Oncol* Biol* Phys"}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814024001075?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814024001075?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T05:29:09Z","timestamp":1759123749000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814024001075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":32,"alternative-id":["S0167814024001075"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2024.110186","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The role of 18F-FDG PET in minimizing variability in gross tumor volume delineation of soft tissue sarcomas","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2024.110186","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"110186"}}