{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T03:45:27Z","timestamp":1794109527419,"version":"4.8.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T00:00:00Z","timestamp":1777075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thegreenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Radiotherapy and Oncology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.radonc.2026.111547","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:36:52Z","timestamp":1777527412000},"page":"111547","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Factors associated with arm swelling in patients undergoing surgery and radiotherapy for breast cancer within the FAST-Forward trial nodal sub-study"],"prefix":"10.1016","volume":"220","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8583-1066","authenticated-orcid":false,"given":"Saranya","family":"Ravindra","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0973-660X","authenticated-orcid":false,"given":"Fay H.","family":"Cafferty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Gulliford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Miles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5690-8630","authenticated-orcid":false,"given":"Jaymini","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9157-9710","authenticated-orcid":false,"given":"Mark A.","family":"Sydenham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sambhav","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3564-1177","authenticated-orcid":false,"given":"Zohal","family":"Nabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0434-8034","authenticated-orcid":false,"given":"Sarah","family":"Mason","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4351-8136","authenticated-orcid":false,"given":"Simeon","family":"Nill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Dunlop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4797-5097","authenticated-orcid":false,"given":"A. Murray","family":"Brunt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith M.","family":"Bliss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5528-1669","authenticated-orcid":false,"given":"Anna M.","family":"Kirby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.radonc.2026.111547_b0005","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S1470-2045(13)70076-7","article-title":"Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis","volume":"14","author":"DiSipio","year":"2013","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0010","article-title":"Self-reported signs and symptoms of secondary upper limb lymphoedema related to breast cancer treatment: Systematic review","volume":"30","author":"Gursen","year":"2021","journal-title":"Eur J Cancer Care (Engl)"},{"key":"10.1016\/j.radonc.2026.111547_b0015","first-page":"79","article-title":"Impact of breast cancer-related lymphedema on working women","volume":"28","author":"Vignes","year":"2020","journal-title":"Supp Care Cancer"},{"key":"10.1016\/j.radonc.2026.111547_b0020","first-page":"665","article-title":"Upper limb function and quality of life in breast cancer related lymphedema: a cross-sectional study","volume":"49","author":"Pinto","year":"2013","journal-title":"Eur J Phys Rehabil Med"},{"key":"10.1016\/j.radonc.2026.111547_b0025","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1001\/jama.2017.11470","article-title":"Effect of axillary dissection vs no axillary dissection on 10-year overall survival among women with invasive breast cancer and sentinel node metastasis: the ACOSOG Z0011 (Alliance) randomized clinical trial","volume":"318","author":"Giuliano","year":"2017","journal-title":"J Am Med Assoc"},{"key":"10.1016\/j.radonc.2026.111547_b0030","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1016\/j.ejso.2012.05.008","article-title":"Association of breast tumour bed seroma with post-operative complications and late normal tissue toxicity: results from the Cambridge Breast IMRT trial","volume":"38","author":"Mukesh","year":"2012","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0035","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1016\/S1470-2045(14)70460-7","article-title":"Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial","volume":"15","author":"Donker","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0040","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.ijrobp.2019.06.2509","article-title":"Determining the organ at risk for lymphedema after regional nodal irradiation in breast cancer","volume":"105","author":"Gross","year":"2019","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111547_b0045","article-title":"Incorporating axillary-lateral thoracic vessel juncture dosimetric variables improves model for predicting lymphedema in patients with breast cancer: a validation analysis","volume":"41","author":"Suk Chang","year":"2023","journal-title":"Clin Transl Radiat Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0050","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ijrobp.2023.04.003","article-title":"The axillary lateral vessel thoracic junction is not an organ at risk for breast cancer-related lymphedema","volume":"117","author":"Healy","year":"2023","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111547_b0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2025.110915","article-title":"Patient- and clinician-assessed five-year normal tissue effects following one-week versus three-week axillary radiotherapy for breast cancer: results from the phase III FAST-Forward trial randomised nodal sub-study","volume":"207","author":"Brunt","year":"2025","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0060","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1016\/S0140-6736(20)30932-6","article-title":"Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial","volume":"395","author":"Murray Brunt","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.radonc.2026.111547_b0065","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.radonc.2014.11.030","article-title":"ESTRO consensus guideline on target volume delineation for elective radiation therapy of early stage breast cancer","volume":"114","author":"Offersen","year":"2015","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0070","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0167-8140(83)80021-8","article-title":"A new isoeffect curve for change in dose per fraction","volume":"1","author":"Withers","year":"1983","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0075","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1200\/JCO.22.01565","article-title":"Radiotherapy or Surgery of the Axilla after a positive Sentinel Node in Breast Cancer: 10-Year results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial","volume":"41","author":"Bartels","year":"2023","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0080","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.ejso.2016.12.011","article-title":"Eight-year follow up result of the OTOASOR trial: the optimal treatment of the axilla - surgery or radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: a randomized, single centre, phase III, non-inferiority trial","volume":"43","author":"S\u00e1volt","year":"2017","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0085","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1056\/NEJMoa2313487","article-title":"Omitting axillary dissection in breast cancer with sentinel-node metastases","volume":"390","author":"de Boniface","year":"2024","journal-title":"N Engl J Med"},{"key":"10.1016\/j.radonc.2026.111547_b0090","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s10549-013-2715-7","article-title":"Impact of body mass index and weight fluctuation on lymphedema risk in patients treated for breast cancer","volume":"142","author":"Jammallo","year":"2013","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.radonc.2026.111547_b0095","first-page":"991","article-title":"Risk factors and prediction model for persistent breast-cancer-related lymphedema: a 5-year cohort study","volume":"27","author":"Penn","year":"2019","journal-title":"Supp Care Cancer"},{"key":"10.1016\/j.radonc.2026.111547_b0100","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.clon.2016.01.011","article-title":"Do patient-reported outcome measures agree with clinical and photographic assessments of normal tissue effects after breast radiotherapy? The experience of the Standardisation of Breast Radiotherapy (START) trials in early breast cancer","volume":"28","author":"Haviland","year":"2016","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"10.1016\/j.radonc.2026.111547_b0105","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.radonc.2018.07.006","article-title":"Impact of modern-day axillary treatment on patient reported arm morbidity and physical functioning in breast cancer patients","volume":"131","author":"Gregorowitsch","year":"2019","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0110","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1016\/j.ijrobp.2023.01.056","article-title":"Development and validation of a normal tissue complication probability model for lymphedema after radiation therapy in breast cancer","volume":"116","author":"Park","year":"2023","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.radonc.2026.111547_b0115","first-page":"301","article-title":"Lymphedema and axillary-lateral thoracic vessel juncture irradiation: a clinical dilemma","volume":"21","author":"\u015eeny\u00fcrek","year":"2025","journal-title":"Eur J Breast Health"},{"key":"10.1016\/j.radonc.2026.111547_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2024.110372","article-title":"Quality assessment of radiotherapy in the prospective randomized SENOMAC trial","volume":"197","author":"Alkner","year":"2024","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0125","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.radonc.2019.01.036","article-title":"Can patient-reported outcomes be used instead of clinician-reported outcomes and photographs as primary endpoints of late normal tissue effects in breast radiotherapy trials? results from the IMPORT LOW trial","volume":"134","author":"Bhattacharya","year":"2019","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.radonc.2026.111547_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.radonc.2026.111454","article-title":"Association between shoulder joint radiation dose and arm morbidity in the randomized breast cancer trial SENOMAC","volume":"218","author":"Alkner","year":"2026","journal-title":"Radiother Oncol"}],"updated-by":[{"DOI":"10.1016\/j.radonc.2026.111547","type":"removal","label":"Removal","source":"publisher","updated":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000}}],"container-title":["Radiotherapy and Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814026003865?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167814026003865?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T12:48:50Z","timestamp":1783169330000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167814026003865"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":26,"alternative-id":["S0167814026003865"],"URL":"https:\/\/doi.org\/10.1016\/j.radonc.2026.111547","relation":{},"ISSN":["0167-8140"],"issn-type":[{"value":"0167-8140","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Factors associated with arm swelling in patients undergoing surgery and radiotherapy for breast cancer within the FAST-Forward trial nodal sub-study","name":"articletitle","label":"Article Title"},{"value":"Radiotherapy and Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.radonc.2026.111547","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"111547"}}